Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 238028395

GI number: 238028395

Start: 3240424

End: 3241818

Strand: Direct

Name: argD [H]

Synonym: bglu_1g28590

Alternate gene names: 238028395

Gene position: 3240424-3241818 (Clockwise)

Preceding gene: 238028394

Following gene: 238028396

Centisome position: 82.95

GC content: 66.24

Gene sequence:

>1395_bases
GTGCGGCTCGATGCCGTATGCTTGCGCCATGAACCGCTTCCTGTCCGCCCTCCGACGCCGCTCGCCGCTCCTCATGGATG
CCGCAGGCTCGTCACGGACGCACGCGTAACCCCCTCCTCGTTACGCCAAGCTGTTCGGACCACCAAGCCACGGCATTCCG
TGGCTTTTTTATTGTCTTTTTCCCGTCGCTACCCGCTGGAGCTCGCCGCCATGCCTTTGAACGAATATCCGATCGACTCG
CTGATGTACATCACGAACCGCCCTGACATCGTGTTCACGCACGGCAAGGGTTCGTGGCTCTACGATCACACCGGCAAGCG
CTATCTGGATTTCATCCAGGGCTGGGCGGTAAATGCGCTCGGTCACTGCAACGAAGGCATGGTCGAGGCGCTGAAATCGC
AGGCCGAGACGCTGCTGAACCCGTCGCCGGCGTTCTACAACGAGCCGATGGCGCGGCTCGCCGCGCTGCTCACGCAGCAC
AGCGTGTTCGACAAGGTGTTCTTCGCCAACAGCGGCGCGGAAGCGAACGAAGGCGCGATCAAGCTCGCACGCAAGTGGGG
CCGCAAGTTCCGCAACGGCGCCTACGAGATCATCACGTTCGACCACAGCTTCCACGGCCGCACGCTCGCGACCATGTCGG
CGAGCGGCAAGCCGGGCTGGGACACGATCTACGCGCCGCAGGTGCCGGGCTTCCCGAAGGCCGACCTGAACGACATCGCC
TCGGTCGAGAAGCTGATCAACGAGAAGACCGTGGCGGTCATGCTCGAACCGATCCAGGGCGAAGGCGGCGTGATCCCGGC
CACGCGCGAATTCATGCAGCAGCTGCGCGCGCTGACCCAGCAGCACGGCCTGCTGCTGATCGTCGACGAAGTGCAAAGCG
GCTGCGGCCGCGCGGGCACGCTGTTCGCCTACGAGCTGGCCGGCGTCGAGCCGGACATCATGACGCTCGGCAAGGGCATC
GGCGGCGGCGTGCCGCTCGCCGCCCTGCTCTCGAAAGCCGAGGTCGCGGTGTTCGAGGCGGGCGACCAGGGCGGCACCTA
CAACGGCAACCCGCTGATGACGGCGGTCGGCCATTCGGTGATCTCGCAGCTGGTCGCGCCGGGCTTCCTCGAAGGCGTGC
GCGAGCGCGGCGAATACCTGAAGCGGCGCCTGCTCGAGCTGTCGGAGGAGCGCGGCTTCGCGGGCGAGCGCGGCGAGGGG
CTGCTGCGCGCGCTGCTGCTCGGCAAGGACATCGGCCCGCAGATCGTCGAAAGGGCGCGCGAAATGCAGCCCGACGGCCT
GCTGCTGAACGCGGCGCGCCCCAACCTGCTGCGCTTCATGCCGGCGCTGAACGTGACGAACGAGGAAATCGACCAGATGA
TGGCGATGCTGCGTTCGATCCTCGACACCCTCTGA

Upstream 100 bases:

>100_bases
CGCCCACGCCGTCTGAGCGCATCGGCGCGCGTGCCCGGCGGCGCGGAACGCGGAAATTCGCGCGGCGACACCCGTTTGTC
GCAACCAGGCGGTTTACTTG

Downstream 100 bases:

>100_bases
GCCTTCCCGGGAGCCGCCCATGCGCCTCGACGACGACGTGACGATCCGCGCCTTCGCGCGCGCCGATACCGAGCCCGTGA
TCGCGCTGTGGGCCGACGCG

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MRLDAVCLRHEPLPVRPPTPLAAPHGCRRLVTDARVTPSSLRQAVRTTKPRHSVAFLLSFSRRYPLELAAMPLNEYPIDS
LMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNALGHCNEGMVEALKSQAETLLNPSPAFYNEPMARLAALLTQH
SVFDKVFFANSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKADLNDIA
SVEKLINEKTVAVMLEPIQGEGGVIPATREFMQQLRALTQQHGLLLIVDEVQSGCGRAGTLFAYELAGVEPDIMTLGKGI
GGGVPLAALLSKAEVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFLEGVRERGEYLKRRLLELSEERGFAGERGEG
LLRALLLGKDIGPQIVERAREMQPDGLLLNAARPNLLRFMPALNVTNEEIDQMMAMLRSILDTL

Sequences:

>Translated_464_residues
MRLDAVCLRHEPLPVRPPTPLAAPHGCRRLVTDARVTPSSLRQAVRTTKPRHSVAFLLSFSRRYPLELAAMPLNEYPIDS
LMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNALGHCNEGMVEALKSQAETLLNPSPAFYNEPMARLAALLTQH
SVFDKVFFANSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKADLNDIA
SVEKLINEKTVAVMLEPIQGEGGVIPATREFMQQLRALTQQHGLLLIVDEVQSGCGRAGTLFAYELAGVEPDIMTLGKGI
GGGVPLAALLSKAEVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFLEGVRERGEYLKRRLLELSEERGFAGERGEG
LLRALLLGKDIGPQIVERAREMQPDGLLLNAARPNLLRFMPALNVTNEEIDQMMAMLRSILDTL
>Mature_464_residues
MRLDAVCLRHEPLPVRPPTPLAAPHGCRRLVTDARVTPSSLRQAVRTTKPRHSVAFLLSFSRRYPLELAAMPLNEYPIDS
LMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNALGHCNEGMVEALKSQAETLLNPSPAFYNEPMARLAALLTQH
SVFDKVFFANSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKADLNDIA
SVEKLINEKTVAVMLEPIQGEGGVIPATREFMQQLRALTQQHGLLLIVDEVQSGCGRAGTLFAYELAGVEPDIMTLGKGI
GGGVPLAALLSKAEVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFLEGVRERGEYLKRRLLELSEERGFAGERGEG
LLRALLLGKDIGPQIVERAREMQPDGLLLNAARPNLLRFMPALNVTNEEIDQMMAMLRSILDTL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=31.7460317460317, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=31.2080536912752, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=28.1030444964871, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI37574042, Length=409, Percent_Identity=30.8068459657702, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI226442705, Length=409, Percent_Identity=30.0733496332518, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=30.6701030927835, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=27.4038461538462, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=23.3100233100233, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=23.3100233100233, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=23.3100233100233, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788044, Length=386, Percent_Identity=43.2642487046632, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1789759, Length=369, Percent_Identity=42.5474254742547, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=34.1708542713568, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI145693181, Length=392, Percent_Identity=30.6122448979592, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787560, Length=399, Percent_Identity=31.8295739348371, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=32.5301204819277, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786991, Length=328, Percent_Identity=30.4878048780488, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=32.3684210526316, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI32564660, Length=417, Percent_Identity=27.5779376498801, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=32.5925925925926, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=415, Percent_Identity=28.6746987951807, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=30.6748466257669, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=347, Percent_Identity=27.0893371757925, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=33.6658354114713, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=397, Percent_Identity=31.4861460957179, Blast_Score=189, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=24.7663551401869, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324386, Length=485, Percent_Identity=25.5670103092783, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=32.5396825396825, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=28.0487804878049, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=27.710843373494, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21356575, Length=424, Percent_Identity=27.8301886792453, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=24.1784037558685, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=24.1784037558685, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=24.1784037558685, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 50861; Mature: 50861

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDAVCLRHEPLPVRPPTPLAAPHGCRRLVTDARVTPSSLRQAVRTTKPRHSVAFLLSF
CCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
SRRYPLELAAMPLNEYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNAL
CCCCCCEEEECCCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHH
GHCNEGMVEALKSQAETLLNPSPAFYNEPMARLAALLTQHSVFDKVFFANSGAEANEGAI
HCCCHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
KLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKADLNDIA
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCHHHHH
SVEKLINEKTVAVMLEPIQGEGGVIPATREFMQQLRALTQQHGLLLIVDEVQSGCGRAGT
HHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCC
LFAYELAGVEPDIMTLGKGIGGGVPLAALLSKAEVAVFEAGDQGGTYNGNPLMTAVGHSV
EEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHH
ISQLVAPGFLEGVRERGEYLKRRLLELSEERGFAGERGEGLLRALLLGKDIGPQIVERAR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
EMQPDGLLLNAARPNLLRFMPALNVTNEEIDQMMAMLRSILDTL
HCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRLDAVCLRHEPLPVRPPTPLAAPHGCRRLVTDARVTPSSLRQAVRTTKPRHSVAFLLSF
CCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
SRRYPLELAAMPLNEYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNAL
CCCCCCEEEECCCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHH
GHCNEGMVEALKSQAETLLNPSPAFYNEPMARLAALLTQHSVFDKVFFANSGAEANEGAI
HCCCHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
KLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKADLNDIA
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCHHHHH
SVEKLINEKTVAVMLEPIQGEGGVIPATREFMQQLRALTQQHGLLLIVDEVQSGCGRAGT
HHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCC
LFAYELAGVEPDIMTLGKGIGGGVPLAALLSKAEVAVFEAGDQGGTYNGNPLMTAVGHSV
EEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHH
ISQLVAPGFLEGVRERGEYLKRRLLELSEERGFAGERGEGLLRALLLGKDIGPQIVERAR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
EMQPDGLLLNAARPNLLRFMPALNVTNEEIDQMMAMLRSILDTL
HCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]