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The map label for this gene is kdpE [H]

Identifier: 238028172

GI number: 238028172

Start: 2987643

End: 2988341

Strand: Reverse

Name: kdpE [H]

Synonym: bglu_1g26240

Alternate gene names: 238028172

Gene position: 2988341-2987643 (Counterclockwise)

Preceding gene: 238028173

Following gene: 238028171

Centisome position: 76.5

GC content: 70.53

Gene sequence:

>699_bases
ATGAGTGAACCGACGCTGACCGTCGTCCTGATCGAAGACGAAAAACAGATCCGCCGCTTCGTGCGCACCGCGCTCGAGGC
CGAGGGCATCGCCGTGTTCGATGCCGAGACCGGCAAGCAGGGGCTGATCGAGACGGCCACGCGCAAGCCCGATCTGGTCA
TCGTCGATCTCGGGCTGCCCGACACCGACGGCCTGGACGTGATCCGCGAGCTGCGCGGCTGGTCCGAGCTGCCGGTGATC
GTCCTGTCGGCGCGCACGCGCGAGGACGAGAAGGTGGCCGCGCTCGACGCCGGGGCCGACGATTACCTGACCAAGCCGTT
CGGCGTGTCCGAGCTGCTGGCGCGGATTCGCGCGCACCTGCGGCGGCGCAACCTCGGCGGCGCGAACGATACGCCGTGCG
TGAAGTTCGGCGCGGTCACGGTGGATCTCGCGCTGCGCGTCGTCACGCGCGCCGGCGCGCCGGTACACCTGACGCCGCTC
GAATACCGCCTGCTCGCGACGCTGGTGCGCCACGCGGGCCGCGTGCTGACGCACCGGCAGCTGCTGCGCGACGTCTGGGG
GCCGTCGCACGTCGAGAGCCACCACTATCTGCGGATCTACATGGCGCATCTGCGCCAGAAGCTCGAGGCCGACCCGGCGC
AGCCGGAGCACATCGTCACCGAAACCGGCGTGGGCTACCGGCTGGTCGGCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCGGCCGGCAGCGCGCCGGACGAGGACGGGCCAGGCGGTGCCGGCCAGACTCGTGCGCGCGTCGCCCGCGCCGCTTTCGA
ACCTCCGTTGAAGCCCGACC

Downstream 100 bases:

>100_bases
GCGGCGGCCGGCTCGGCAAGCGGCAGCGATGCGGGAGCCGCGGCCGGTAACTACGGTCGGCTTTTTGTCGTGATTTTGAT
ATAATTCGGGCCGAACCGGG

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSEPTLTVVLIEDEKQIRRFVRTALEAEGIAVFDAETGKQGLIETATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPVI
VLSARTREDEKVAALDAGADDYLTKPFGVSELLARIRAHLRRRNLGGANDTPCVKFGAVTVDLALRVVTRAGAPVHLTPL
EYRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAA

Sequences:

>Translated_232_residues
MSEPTLTVVLIEDEKQIRRFVRTALEAEGIAVFDAETGKQGLIETATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPVI
VLSARTREDEKVAALDAGADDYLTKPFGVSELLARIRAHLRRRNLGGANDTPCVKFGAVTVDLALRVVTRAGAPVHLTPL
EYRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAA
>Mature_231_residues
SEPTLTVVLIEDEKQIRRFVRTALEAEGIAVFDAETGKQGLIETATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPVIV
LSARTREDEKVAALDAGADDYLTKPFGVSELLARIRAHLRRRNLGGANDTPCVKFGAVTVDLALRVVTRAGAPVHLTPLE
YRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=64.5739910313901, Blast_Score=297, Evalue=5e-82,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=36.9369369369369, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.8407079646018, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=37.3333333333333, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=34.6666666666667, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=32.4444444444444, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=32.9004329004329, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=32.3275862068966, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.4444444444444, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=35.1111111111111, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.0043668122271, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=30.8695652173913, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=30.7017543859649, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.3842794759825, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.9622641509434, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788191, Length=126, Percent_Identity=29.3650793650794, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI48994928, Length=121, Percent_Identity=39.6694214876033, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25679; Mature: 25548

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPTLTVVLIEDEKQIRRFVRTALEAEGIAVFDAETGKQGLIETATRKPDLVIVDLGLP
CCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSELPVIVLSARTREDEKVAALDAGADDYLTKPFGVSELLARIRAHL
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHH
RRRNLGGANDTPCVKFGAVTVDLALRVVTRAGAPVHLTPLEYRLLATLVRHAGRVLTHRQ
HHCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
LLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCC
>Mature Secondary Structure 
SEPTLTVVLIEDEKQIRRFVRTALEAEGIAVFDAETGKQGLIETATRKPDLVIVDLGLP
CCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSELPVIVLSARTREDEKVAALDAGADDYLTKPFGVSELLARIRAHL
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHH
RRRNLGGANDTPCVKFGAVTVDLALRVVTRAGAPVHLTPLEYRLLATLVRHAGRVLTHRQ
HHCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
LLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]