Click here to switch to the map view.

The map label for this gene is ychM [C]

Identifier: 238027546

GI number: 238027546

Start: 2146539

End: 2148260

Strand: Reverse

Name: ychM [C]

Synonym: bglu_1g19640

Alternate gene names: 238027546

Gene position: 2148260-2146539 (Counterclockwise)

Preceding gene: 238027547

Following gene: 238027545

Centisome position: 54.99

GC content: 71.95

Gene sequence:

>1722_bases
ATGCGCCAGTCGCGCCATGCCGTGATCCGGCCGACGTCGACGCGGGCGGTGTCCGAGGCGATGCCGCACGATGCCGCTCA
TGTTTCGCCGCGCGCCGCGCCCGACCCGACGCGCGGCGCGCGGCGCTGGCGCGACGCGCTGGCCGGCCTGTCGATCGCCG
GGCTGCTGATTCCCGAGGCGGTCGCCTATGCCGGGCTCGCGAACCTGCCGCCGCAGGCCGGCCTGATCGCGCTGCTGGTC
GGGCTGGTGGTCTACGCGGCGCTCGGCAGCAGCCGCTTCGCGATCGTCTCGTCGACCTCGTCGTCGGCCGCCGTGCTGGC
CGCCACCGTGCTGTCCGAGACCGGCACCAGCGCGGCCGAGCAGCTTGCGCTCGCGGCCGCGCTGGTGGCCGCCACCGGCC
TGCTGTTCGTGATCGCGGGCGCCGCGCGGCTCGGCGGCATCTCGGACTTCATCGCGCGGCCCGTGCTGCGCGGCTTCACG
TTCGGGCTCGCGCTGACGATCGTGATCAAGCAGTTGCCGAAGATCCTCGTGGTCCCCGTGCATCACAGCGATACGCCGCA
GGTGGCGCTGGACCTCGTGCGCGGCCTGCCGCACGCCAACCTCGCCAGCCTCGCGCTCGGCGCCGCGGCGCTCGCGATCC
TGTTCGCGCTCGGCCGGCGCTCGCGCGTGCCGGCCACGCTGATCGTGATCGTGCTCGGCATCGCGGCCGGTTATGGGATC
GACTGGGCAGCTCATGGCATCGCCGTGGTCGGGCATATCGACCTGCAGCATCTCTCGTTCGGGCTGCCGTCGCTCGATCG
CGCCGGCTGGACGCAGACCGTGGAGCTCGGCTTCGCGCTGATGCTGATCCTGTATGCCGAATCGTATGGCTCGATCCGCA
ATTTCGCGCTGAAGCACGGCGACGCGATCGCGCCGAATCGCGATCTGGTCGCGCTCGGCTGCGCGAACCTGGTATCGGGT
CTGCTGCATGGCATGCCCGTGGGCGCCGGTTATTCGGCGAGCTCGGCCAACGAGGCGGCCGGCGCGCAGAGCCGGCTCGC
GGGCGCGTGCGCGGCCGTGGTGATCGGGTTGATCGTCTGGCTGCTGCTGCCGCAGCTCGCGCGCACGCCGGAGCCGGTGC
TCGCCGCGATCGTGATCTTCGCGGTCAGCCACTCGCTGCATCCGGCCGTGTTCCGGCCGTATTGGCTCTGGCACCGCGAC
CGGCTGCTGGCGCTCGCCGCGATTCTCGCGGTGCTCGTGCTCGGCGTGCTGAACGGCCTGCTCGCGGCGATCGCGGCGAG
CCTGCTGCTGACCGTGCGCAAGCTGTCCGAGCCGAAGCTCAGCGAGTTGGGCCGGCTGCGCGACAGCCGCGATTTCGTCG
ACGTGCGCAATCATGCCGATGCGACGCCGGTGCCGGGCATGCTGATCGTCCGACCCGAGGGGCAGCTGTTCTTCGCGAAC
GCGGAGCGCGTGCTGGGGCGGGTTCGGCAACTGGGGCGCGCGGTCAGGGGGCTGCGGACGGTGGTGCTGAGCCTCGAGGA
ATCGCCGGATCTCGATGGCACCGCGATCGAGGCGCTGATCACGTTCGCCGCCGAATGCGAGGCGCGCGGCTGGCGGCTGG
CGCTGGTGCGCTTGAAGCCGGAAGTGCTCGAGGTGCTGCGGCGAGCCAGTGGCGGGGGGCTCGGTGAGGACGCGCTCTCG
GAGTTGAGCGTCGATGATGCGGTGGGGCGGCTGGCAGGGTGA

Upstream 100 bases:

>100_bases
CATTTCTCGAAGGCGCTCGACGCGGCGCTCGCCCATGCGCATGCGCCCGACGCACGCTATCTGCCTGGCTGGTCCGGCGT
GTTCGAGCCGAGGCCCTGAG

Downstream 100 bases:

>100_bases
GGCCTGACTTGACGCGTCGCTTCACGAAGCCTCGTGCCCGCCCATGGCTCAGGCATGCTGCTTTCCGGGCAGCAATGAAA
AAGGCCGGCGTTTAGCCGGC

Product: sulfate transporter/antisigma-factor antagonist STAS

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MRQSRHAVIRPTSTRAVSEAMPHDAAHVSPRAAPDPTRGARRWRDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLV
GLVVYAALGSSRFAIVSSTSSSAAVLAATVLSETGTSAAEQLALAAALVAATGLLFVIAGAARLGGISDFIARPVLRGFT
FGLALTIVIKQLPKILVVPVHHSDTPQVALDLVRGLPHANLASLALGAAALAILFALGRRSRVPATLIVIVLGIAAGYGI
DWAAHGIAVVGHIDLQHLSFGLPSLDRAGWTQTVELGFALMLILYAESYGSIRNFALKHGDAIAPNRDLVALGCANLVSG
LLHGMPVGAGYSASSANEAAGAQSRLAGACAAVVIGLIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWLWHRD
RLLALAAILAVLVLGVLNGLLAAIAASLLLTVRKLSEPKLSELGRLRDSRDFVDVRNHADATPVPGMLIVRPEGQLFFAN
AERVLGRVRQLGRAVRGLRTVVLSLEESPDLDGTAIEALITFAAECEARGWRLALVRLKPEVLEVLRRASGGGLGEDALS
ELSVDDAVGRLAG

Sequences:

>Translated_573_residues
MRQSRHAVIRPTSTRAVSEAMPHDAAHVSPRAAPDPTRGARRWRDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLV
GLVVYAALGSSRFAIVSSTSSSAAVLAATVLSETGTSAAEQLALAAALVAATGLLFVIAGAARLGGISDFIARPVLRGFT
FGLALTIVIKQLPKILVVPVHHSDTPQVALDLVRGLPHANLASLALGAAALAILFALGRRSRVPATLIVIVLGIAAGYGI
DWAAHGIAVVGHIDLQHLSFGLPSLDRAGWTQTVELGFALMLILYAESYGSIRNFALKHGDAIAPNRDLVALGCANLVSG
LLHGMPVGAGYSASSANEAAGAQSRLAGACAAVVIGLIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWLWHRD
RLLALAAILAVLVLGVLNGLLAAIAASLLLTVRKLSEPKLSELGRLRDSRDFVDVRNHADATPVPGMLIVRPEGQLFFAN
AERVLGRVRQLGRAVRGLRTVVLSLEESPDLDGTAIEALITFAAECEARGWRLALVRLKPEVLEVLRRASGGGLGEDALS
ELSVDDAVGRLAG
>Mature_573_residues
MRQSRHAVIRPTSTRAVSEAMPHDAAHVSPRAAPDPTRGARRWRDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLV
GLVVYAALGSSRFAIVSSTSSSAAVLAATVLSETGTSAAEQLALAAALVAATGLLFVIAGAARLGGISDFIARPVLRGFT
FGLALTIVIKQLPKILVVPVHHSDTPQVALDLVRGLPHANLASLALGAAALAILFALGRRSRVPATLIVIVLGIAAGYGI
DWAAHGIAVVGHIDLQHLSFGLPSLDRAGWTQTVELGFALMLILYAESYGSIRNFALKHGDAIAPNRDLVALGCANLVSG
LLHGMPVGAGYSASSANEAAGAQSRLAGACAAVVIGLIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWLWHRD
RLLALAAILAVLVLGVLNGLLAAIAASLLLTVRKLSEPKLSELGRLRDSRDFVDVRNHADATPVPGMLIVRPEGQLFFAN
AERVLGRVRQLGRAVRGLRTVVLSLEESPDLDGTAIEALITFAAECEARGWRLALVRLKPEVLEVLRRASGGGLGEDALS
ELSVDDAVGRLAG

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721253, Length=468, Percent_Identity=27.7777777777778, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI94721255, Length=468, Percent_Identity=27.7777777777778, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI94721259, Length=468, Percent_Identity=27.7777777777778, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI94721257, Length=468, Percent_Identity=27.7777777777778, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI45827800, Length=472, Percent_Identity=24.1525423728814, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI39752683, Length=472, Percent_Identity=24.1525423728814, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI16418413, Length=477, Percent_Identity=26.4150943396226, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI217272867, Length=477, Percent_Identity=26.4150943396226, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI47131207, Length=637, Percent_Identity=25.5886970172684, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI20336272, Length=637, Percent_Identity=25.5886970172684, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI269784651, Length=469, Percent_Identity=23.8805970149254, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI4557535, Length=596, Percent_Identity=23.489932885906, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI45827802, Length=435, Percent_Identity=24.367816091954, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4505697, Length=489, Percent_Identity=22.9038854805726, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI100913030, Length=489, Percent_Identity=22.9038854805726, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI20336282, Length=480, Percent_Identity=20.8333333333333, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI16306483, Length=480, Percent_Identity=20.8333333333333, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI262206105, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI262206075, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI262206069, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI262206063, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081859, Length=546, Percent_Identity=25.8241758241758, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551690, Length=512, Percent_Identity=25, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17566848, Length=571, Percent_Identity=27.3204903677758, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI86565215, Length=503, Percent_Identity=23.8568588469185, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86564876, Length=521, Percent_Identity=22.2648752399232, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI86564196, Length=475, Percent_Identity=22.3157894736842, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562578, Length=499, Percent_Identity=23.6472945891784, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325260, Length=556, Percent_Identity=23.5611510791367, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323121, Length=459, Percent_Identity=22.6579520697168, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651449, Length=551, Percent_Identity=23.956442831216, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24649801, Length=565, Percent_Identity=23.716814159292, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21358229, Length=582, Percent_Identity=24.0549828178694, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24666186, Length=514, Percent_Identity=24.3190661478599, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24663084, Length=525, Percent_Identity=25.3333333333333, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357695, Length=525, Percent_Identity=25.3333333333333, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21358633, Length=415, Percent_Identity=23.855421686747, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19922482, Length=522, Percent_Identity=22.2222222222222, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI85815873, Length=432, Percent_Identity=22.6851851851852, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59730; Mature: 59730

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSRHAVIRPTSTRAVSEAMPHDAAHVSPRAAPDPTRGARRWRDALAGLSIAGLLIPEA
CCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAYAGLANLPPQAGLIALLVGLVVYAALGSSRFAIVSSTSSSAAVLAATVLSETGTSAAE
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHH
QLALAAALVAATGLLFVIAGAARLGGISDFIARPVLRGFTFGLALTIVIKQLPKILVVPV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
HHSDTPQVALDLVRGLPHANLASLALGAAALAILFALGRRSRVPATLIVIVLGIAAGYGI
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
DWAAHGIAVVGHIDLQHLSFGLPSLDRAGWTQTVELGFALMLILYAESYGSIRNFALKHG
CHHHCCEEEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAIAPNRDLVALGCANLVSGLLHGMPVGAGYSASSANEAAGAQSRLAGACAAVVIGLIVW
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
LLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWLWHRDRLLALAAILAVLVLGVLNGL
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIAASLLLTVRKLSEPKLSELGRLRDSRDFVDVRNHADATPVPGMLIVRPEGQLFFAN
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCCCEEECC
AERVLGRVRQLGRAVRGLRTVVLSLEESPDLDGTAIEALITFAAECEARGWRLALVRLKP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECH
EVLEVLRRASGGGLGEDALSELSVDDAVGRLAG
HHHHHHHHHCCCCCCHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MRQSRHAVIRPTSTRAVSEAMPHDAAHVSPRAAPDPTRGARRWRDALAGLSIAGLLIPEA
CCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAYAGLANLPPQAGLIALLVGLVVYAALGSSRFAIVSSTSSSAAVLAATVLSETGTSAAE
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHH
QLALAAALVAATGLLFVIAGAARLGGISDFIARPVLRGFTFGLALTIVIKQLPKILVVPV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
HHSDTPQVALDLVRGLPHANLASLALGAAALAILFALGRRSRVPATLIVIVLGIAAGYGI
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
DWAAHGIAVVGHIDLQHLSFGLPSLDRAGWTQTVELGFALMLILYAESYGSIRNFALKHG
CHHHCCEEEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAIAPNRDLVALGCANLVSGLLHGMPVGAGYSASSANEAAGAQSRLAGACAAVVIGLIVW
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
LLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWLWHRDRLLALAAILAVLVLGVLNGL
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIAASLLLTVRKLSEPKLSELGRLRDSRDFVDVRNHADATPVPGMLIVRPEGQLFFAN
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCCCEEECC
AERVLGRVRQLGRAVRGLRTVVLSLEESPDLDGTAIEALITFAAECEARGWRLALVRLKP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECH
EVLEVLRRASGGGLGEDALSELSVDDAVGRLAG
HHHHHHHHHCCCCCCHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]