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The map label for this gene is grsT [H]

Identifier: 238027513

GI number: 238027513

Start: 2112136

End: 2112924

Strand: Reverse

Name: grsT [H]

Synonym: bglu_1g19270

Alternate gene names: 238027513

Gene position: 2112924-2112136 (Counterclockwise)

Preceding gene: 238027514

Following gene: 238027512

Centisome position: 54.09

GC content: 56.65

Gene sequence:

>789_bases
TTGCCATTTCCCCCTGATTCCGAGACCGAAAGAGAAAGCCGGCACGACCTCCGATGGCTAGCCCCCAATCTTCTCGATCC
AACTGCAGTCCCAATTGGCCGCGTGTTCTGTATTCCGCACGCGGGCGGCACTTCTTCACTATTTGCACGGTGGCCCAGCC
TTTTTTTGCCCGACATTGAAGTCTGTGGAATCGATTTGCCTGGCCGCGGAACCCGTTTCAAGGAACCGTTCGTAACCGAT
ATGCTGTACCTCGCTTCGCAAATCGCAAGGGTCATCGCAAGAATTGCCGACGTACCTTTCGCGATCTACGGAGAGTGCAG
TGGCGGACTGATAGCGCTGGCTACCGCGCGCGCGCTGGCAAGCGAGCATCAGCTCGTGCCTACGCACCTGTTTGCAACAG
GCATGAAGAGTCCCCGCGTTGGCAGTGGCCGTGGTGTCTATCGATTTTCCGATGAGGACCTGCAACGCGAGATCGTCGAA
AAAGGCCTGCTCGATCCGGCAATTGCCTCGAATAGCGAGGCCATGGAATTTTTCCTGCCGCAGATCCGCGCCGATTACGA
ATTGTGCGAAACCTATGAGTCGTCCTCGCATGATCGCATAGGCTGCCCAATCACCACCATCGCGAATTCGAGAGACTTTC
ATGCCGCACCGGCCGCTTTCGAAGACTGGAGGAACGAGACAGCTGTTGTCTGGCAGCATTTCGCAATCAACTTCCCCATG
GTGGCGAGCGACCCAGACAAATTACTGAAGTCGCTAATTCGACAGACCCTGGTCGGCGGCGTGCGGTAG

Upstream 100 bases:

>100_bases
TTCAGACGATTCTCTTCCTATCGGTGAACAGGAATTTTCGCTACACTTCTGAGTGCCCTGATGACTTCCGGATCAACATC
GAATTACGCGGAGGCATGCC

Downstream 100 bases:

>100_bases
AAAACACCACTGTCGGTCACGATCGTCGCGACAGGAGTGCATGCCAACGAGCTTTAACCGCACACCTTCGCTCGCGAGCC
GGGCGCAAAGAGCGGCCGGC

Product: non-ribosomal peptide biosynthesis thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPFPPDSETERESRHDLRWLAPNLLDPTAVPIGRVFCIPHAGGTSSLFARWPSLFLPDIEVCGIDLPGRGTRFKEPFVTD
MLYLASQIARVIARIADVPFAIYGECSGGLIALATARALASEHQLVPTHLFATGMKSPRVGSGRGVYRFSDEDLQREIVE
KGLLDPAIASNSEAMEFFLPQIRADYELCETYESSSHDRIGCPITTIANSRDFHAAPAAFEDWRNETAVVWQHFAINFPM
VASDPDKLLKSLIRQTLVGGVR

Sequences:

>Translated_262_residues
MPFPPDSETERESRHDLRWLAPNLLDPTAVPIGRVFCIPHAGGTSSLFARWPSLFLPDIEVCGIDLPGRGTRFKEPFVTD
MLYLASQIARVIARIADVPFAIYGECSGGLIALATARALASEHQLVPTHLFATGMKSPRVGSGRGVYRFSDEDLQREIVE
KGLLDPAIASNSEAMEFFLPQIRADYELCETYESSSHDRIGCPITTIANSRDFHAAPAAFEDWRNETAVVWQHFAINFPM
VASDPDKLLKSLIRQTLVGGVR
>Mature_261_residues
PFPPDSETERESRHDLRWLAPNLLDPTAVPIGRVFCIPHAGGTSSLFARWPSLFLPDIEVCGIDLPGRGTRFKEPFVTDM
LYLASQIARVIARIADVPFAIYGECSGGLIALATARALASEHQLVPTHLFATGMKSPRVGSGRGVYRFSDEDLQREIVEK
GLLDPAIASNSEAMEFFLPQIRADYELCETYESSSHDRIGCPITTIANSRDFHAAPAAFEDWRNETAVVWQHFAINFPMV
ASDPDKLLKSLIRQTLVGGVR

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI8922871, Length=200, Percent_Identity=26.5, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28985; Mature: 28854

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFPPDSETERESRHDLRWLAPNLLDPTAVPIGRVFCIPHAGGTSSLFARWPSLFLPDIE
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCHHCCCCCC
VCGIDLPGRGTRFKEPFVTDMLYLASQIARVIARIADVPFAIYGECSGGLIALATARALA
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHH
SEHQLVPTHLFATGMKSPRVGSGRGVYRFSDEDLQREIVEKGLLDPAIASNSEAMEFFLP
HCCCCCHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCHHCCCCHHHHHHHH
QIRADYELCETYESSSHDRIGCPITTIANSRDFHAAPAAFEDWRNETAVVWQHFAINFPM
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHCCCHHEEHHHHHCCCCC
VASDPDKLLKSLIRQTLVGGVR
CCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFPPDSETERESRHDLRWLAPNLLDPTAVPIGRVFCIPHAGGTSSLFARWPSLFLPDIE
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCHHCCCCCC
VCGIDLPGRGTRFKEPFVTDMLYLASQIARVIARIADVPFAIYGECSGGLIALATARALA
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHH
SEHQLVPTHLFATGMKSPRVGSGRGVYRFSDEDLQREIVEKGLLDPAIASNSEAMEFFLP
HCCCCCHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCHHCCCCHHHHHHHH
QIRADYELCETYESSSHDRIGCPITTIANSRDFHAAPAAFEDWRNETAVVWQHFAINFPM
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHCCCHHEEHHHHHCCCCC
VASDPDKLLKSLIRQTLVGGVR
CCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]