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The map label for this gene is lgrC [H]

Identifier: 238027507

GI number: 238027507

Start: 2103094

End: 2106324

Strand: Reverse

Name: lgrC [H]

Synonym: bglu_1g19210

Alternate gene names: 238027507

Gene position: 2106324-2103094 (Counterclockwise)

Preceding gene: 238027508

Following gene: 238027506

Centisome position: 53.92

GC content: 59.42

Gene sequence:

>3231_bases
ATGCGCACCAAACTTGGCCCTGACCGTGTTTACTCGCCTGAGGTCAACGATGCAAACACAACCCGATTGTCGATTGCGCA
GGAGAGCTTCTGGCTGTTGAGCCGACATGCGCGAAACGACGGTGCATTCAACGTGAGTCGGGCGTGGCGACTGCGCGGCG
CGTTGGACGAAGCGGCACTGCAAGGTGCGGTGCAGGATGTGGCACACCGACATGACATCCTCAACAGCCACATCGAGGTG
CGCGAGGACATGCCGTACTGGGTCTACGACGCAGGGAGGCCGCTTTGCGTCGAATGTGTGGACCTATCGAGTTCGCCCCA
ATCCGCCATGGACGAGGCGTTTCGTCTCGTTGCCTCCCTGGCTCGAAACGATCTCGATGTCGAGGCCGGTCCGTTGGCGT
CAGTGACGCTCTTTCGTCTTGGCCGTGACGACCACGTGCTGCTCATCGTCCTGCACCATCTGATTTCGGACGCATGGTCG
ATCAAGGTCTTTATCGACGAGGTTTCCCAATGTTATTCGGCTCGTGTGAACGGTGAAGTGGTTGCGCCGGGCCGGCGCCC
CCTCCAGTACATGGACTATGCGTTGCTTCAGAAATGCAATTTGACGACTCCGCTTTTTGAGCGGAAAGCTGCTTTCTGGC
GTTCGCGCTTGTCCGATGTCCCTGCGCCCTTTTCCTTGCCGGCTAGAAGAGTGGTAAAAGAGAGGGGGACCACGACCGGG
GCAGCTCAACAACACGCGCTTTCTCCTTTGGTGATATCCGCCGTCGCGGGATGGGCAGAAACACGCGGGTTGTCGTTGAA
CATGATTTGTCTCGCAGCCTACGCGATGGTGATGGCGCGGCAAAGCGGCCAGAGTGAATTCATGATTTGCATGCCGGTCC
ATTGCAGAACAAAGGTTGAAACGAAGAACATCATAGGGCCCGTGGTCAATCCGCTGGCGATAGCTATTCGCGTAGATCAG
TGCATGACGGTCGAGGACTTCCTATCGGAAGTGCGCCGCGCTGTGCTTGACGCTTACAGGCATCACGAATATCCCCTCGA
AAGGGCCATTCGCGACATAAAGGCCTACGGAGCGGTAAGCTGGCAGGTGCCCTTTAACCTCTTCTTCAATTTCTATAGTG
AGCCGTCGGCCACGCCAATCCTGAGCAGCGTCACTGCAGAAAGGCTGGATCTGGGGCCAAAGGGCGTGAAATTCGACCTC
AGCTTGACCGTTCGAATATCGCACGATAACTCTCGGTACTGCATCGATTACGATTCGTCGCTGTTCGATGCGGCGCAGAT
CGGTGGCGTCTGCCGGCAATTCGAATCGGCATTGACGCGCATCCCGGGGTCGAGCGGGCAGCGTCTAGCGGACATCGAAT
TGCTGTCCGATGAAGAATGGGATGATTTGGTTGAGTGCAGGAATGCAACTCGCGCGGCGTCAGCTCGACAAGGGAGCCTC
GTTGACCGGTTCGCCGAGACGGCCGCCCAGTATGCGGATCGGGTCGCGGTGGCAAGCGGCGACGAGACGTTGACATTTCG
CTCACTAAGTCAGCGATCGACCCAATTCGCGGACTATCTGCGGGCTCAGGGATGCGAACCGCAAGCCATTGTCGCGCTTT
ATTTGCGGCGCTCGCCGGAATTCGTCGTTGCGTTGCTAGCCACCCTGAAGGCGGGCGCCGTTGCGTTACCAATTGACCCG
GTTCTGCCGCAGGCGCGTGTTCAGCATATTCTTCGCGACGCCGGCGCGTCGTGGGTAGTGGCTCACGCCGATACGCTCGG
CGACCTTCCCTCCGGGTCTCATCGCGTTCTCGACGTGAATGCGCCGTTGCCGCCCATCGATCCCCTGATGTCCAGCATAC
CGCCTGACGCGCCTCGATCGATCGAAGACATCGCTTACATTATCTATACGTCGGGTTCCACCGGTATTCCGAAGGGGGTG
ATGGCGACACACCGCGGATTGCTTAATCGAATCGATGCACAGCAGGAAGTCGCACCGTGCGGCCCTGGAAGCATCATTTG
CCAGAAGACGTCCGTCTCGTTCGTCGACAGCGTGTTGGAGATACTCGGTCCCGTCGTCAACGGCGGATTGCTTGCGGTGA
TGCCCGACGACGTTCGATCGAGTATCGCGGGATTCGTCGAGTTTCTCGTCCATCGGCAGGTAACCCACCTCGTCTGTGTG
CCTTCGCTCGCGGAAGCACTACTGCCCGAGATCGTCCGGCAAGCGCCTACGTTAAAGTTGCGCTATTGGGCTTTGAGTGG
CGAACTCTTGCCGGACGAACTTGGCCGCGCGCTGCACCGGATACTGCCGAAATGCACGTTCGTCAATATTTATGGTTCGT
CCGAAGTTGCCGCAGATGCGACGTTTCACTGTTTTTCGGCAAGCCAAGCAGCGCCCTCGTTGATCGGCAAACCGCTGCGC
AACGTTGCCGTCTACGTACTCGACGCAACAATGCACCCGGTGCCCGCCGGCACATGGGGAGAGTTGTATGTGGGCGGAGA
CGGCCTGGCCGCAGGCTATCTCGGTCAGCCGGAACTGACAGCGGCGGCGTTCTTGCCGTCACCCTTCGTTCCGGGCCTGC
GACTGTACCGCACGGGTGATCTGGCAAGGTGGGGAGAAGGTGGCAACCTGGAATACATGGGGCGCGTGGATCGTCAGGTG
AAACTTCGCGGGCAACGCATTGAGCTTGGTGAGATCGAAGCCATCGTCGGCGAACATCCATTCGTTCGCGAGGCGGCGGT
CGTTGCTCGGCCTACGCCGACGGGAAGCCTGCAGCTGAATGTCTATGTGGTCGGCAAGCACGAAGAAACGATCGACGTCG
ACGCGCTTCGTCGGCATCTTGCACGACGTATCCCGGAGGCCGGCCTGCAGACAGCGATCGTAGTGCTTCGGGAATTGCCC
CGAACGGCCAGCGGCAAACTCGATTACGCGGCGTTGCCGACGCGAACTCCTCGCCCCGGCATTAAGCACGTCGCGCCCGC
CACGGCGAACCAGATGCGCTTACTCGATATTTGGCAGGAGGCGCTGAAAATCGATGGCCTCGGCATTCGCGCTGGCTTCT
TCGACCTGGGAGGTGATTCGCTGTCAGCGATGAAGGCCGTGGCGCGCATTGCCGAGCAATGGGGTATTCGGGTTCCGCTA
CGCGCGATGTTCGAACATGACACGGTGGAAGAATTTGCACAGTGGCTGGAGGATCGTCTCGGCGCTGAACGCGCCGATGC
ACAATCGCTGGCCGGAGGAGGCGCTCTATGA

Upstream 100 bases:

>100_bases
TATCCGGCGTTTGGCGAAGGACGCCGGTAGCGAGGTATCGGGCCACCGGCCTGCGGGATAACGATATTCCAGTCAATCCG
GAATGCAATGAGGTGGCGAA

Downstream 100 bases:

>100_bases
ATCTTGACCCGGCTGCGCGCGCTGTTATGTCTCTCCCCGACCGATATGCGCCGGCGCACAATCCTCTGGAGCCCGAGGCA
CTGCCCCGGTGGCTGTCCTG

Product: Non-ribosomal peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1076; Mature: 1076

Protein sequence:

>1076_residues
MRTKLGPDRVYSPEVNDANTTRLSIAQESFWLLSRHARNDGAFNVSRAWRLRGALDEAALQGAVQDVAHRHDILNSHIEV
REDMPYWVYDAGRPLCVECVDLSSSPQSAMDEAFRLVASLARNDLDVEAGPLASVTLFRLGRDDHVLLIVLHHLISDAWS
IKVFIDEVSQCYSARVNGEVVAPGRRPLQYMDYALLQKCNLTTPLFERKAAFWRSRLSDVPAPFSLPARRVVKERGTTTG
AAQQHALSPLVISAVAGWAETRGLSLNMICLAAYAMVMARQSGQSEFMICMPVHCRTKVETKNIIGPVVNPLAIAIRVDQ
CMTVEDFLSEVRRAVLDAYRHHEYPLERAIRDIKAYGAVSWQVPFNLFFNFYSEPSATPILSSVTAERLDLGPKGVKFDL
SLTVRISHDNSRYCIDYDSSLFDAAQIGGVCRQFESALTRIPGSSGQRLADIELLSDEEWDDLVECRNATRAASARQGSL
VDRFAETAAQYADRVAVASGDETLTFRSLSQRSTQFADYLRAQGCEPQAIVALYLRRSPEFVVALLATLKAGAVALPIDP
VLPQARVQHILRDAGASWVVAHADTLGDLPSGSHRVLDVNAPLPPIDPLMSSIPPDAPRSIEDIAYIIYTSGSTGIPKGV
MATHRGLLNRIDAQQEVAPCGPGSIICQKTSVSFVDSVLEILGPVVNGGLLAVMPDDVRSSIAGFVEFLVHRQVTHLVCV
PSLAEALLPEIVRQAPTLKLRYWALSGELLPDELGRALHRILPKCTFVNIYGSSEVAADATFHCFSASQAAPSLIGKPLR
NVAVYVLDATMHPVPAGTWGELYVGGDGLAAGYLGQPELTAAAFLPSPFVPGLRLYRTGDLARWGEGGNLEYMGRVDRQV
KLRGQRIELGEIEAIVGEHPFVREAAVVARPTPTGSLQLNVYVVGKHEETIDVDALRRHLARRIPEAGLQTAIVVLRELP
RTASGKLDYAALPTRTPRPGIKHVAPATANQMRLLDIWQEALKIDGLGIRAGFFDLGGDSLSAMKAVARIAEQWGIRVPL
RAMFEHDTVEEFAQWLEDRLGAERADAQSLAGGGAL

Sequences:

>Translated_1076_residues
MRTKLGPDRVYSPEVNDANTTRLSIAQESFWLLSRHARNDGAFNVSRAWRLRGALDEAALQGAVQDVAHRHDILNSHIEV
REDMPYWVYDAGRPLCVECVDLSSSPQSAMDEAFRLVASLARNDLDVEAGPLASVTLFRLGRDDHVLLIVLHHLISDAWS
IKVFIDEVSQCYSARVNGEVVAPGRRPLQYMDYALLQKCNLTTPLFERKAAFWRSRLSDVPAPFSLPARRVVKERGTTTG
AAQQHALSPLVISAVAGWAETRGLSLNMICLAAYAMVMARQSGQSEFMICMPVHCRTKVETKNIIGPVVNPLAIAIRVDQ
CMTVEDFLSEVRRAVLDAYRHHEYPLERAIRDIKAYGAVSWQVPFNLFFNFYSEPSATPILSSVTAERLDLGPKGVKFDL
SLTVRISHDNSRYCIDYDSSLFDAAQIGGVCRQFESALTRIPGSSGQRLADIELLSDEEWDDLVECRNATRAASARQGSL
VDRFAETAAQYADRVAVASGDETLTFRSLSQRSTQFADYLRAQGCEPQAIVALYLRRSPEFVVALLATLKAGAVALPIDP
VLPQARVQHILRDAGASWVVAHADTLGDLPSGSHRVLDVNAPLPPIDPLMSSIPPDAPRSIEDIAYIIYTSGSTGIPKGV
MATHRGLLNRIDAQQEVAPCGPGSIICQKTSVSFVDSVLEILGPVVNGGLLAVMPDDVRSSIAGFVEFLVHRQVTHLVCV
PSLAEALLPEIVRQAPTLKLRYWALSGELLPDELGRALHRILPKCTFVNIYGSSEVAADATFHCFSASQAAPSLIGKPLR
NVAVYVLDATMHPVPAGTWGELYVGGDGLAAGYLGQPELTAAAFLPSPFVPGLRLYRTGDLARWGEGGNLEYMGRVDRQV
KLRGQRIELGEIEAIVGEHPFVREAAVVARPTPTGSLQLNVYVVGKHEETIDVDALRRHLARRIPEAGLQTAIVVLRELP
RTASGKLDYAALPTRTPRPGIKHVAPATANQMRLLDIWQEALKIDGLGIRAGFFDLGGDSLSAMKAVARIAEQWGIRVPL
RAMFEHDTVEEFAQWLEDRLGAERADAQSLAGGGAL
>Mature_1076_residues
MRTKLGPDRVYSPEVNDANTTRLSIAQESFWLLSRHARNDGAFNVSRAWRLRGALDEAALQGAVQDVAHRHDILNSHIEV
REDMPYWVYDAGRPLCVECVDLSSSPQSAMDEAFRLVASLARNDLDVEAGPLASVTLFRLGRDDHVLLIVLHHLISDAWS
IKVFIDEVSQCYSARVNGEVVAPGRRPLQYMDYALLQKCNLTTPLFERKAAFWRSRLSDVPAPFSLPARRVVKERGTTTG
AAQQHALSPLVISAVAGWAETRGLSLNMICLAAYAMVMARQSGQSEFMICMPVHCRTKVETKNIIGPVVNPLAIAIRVDQ
CMTVEDFLSEVRRAVLDAYRHHEYPLERAIRDIKAYGAVSWQVPFNLFFNFYSEPSATPILSSVTAERLDLGPKGVKFDL
SLTVRISHDNSRYCIDYDSSLFDAAQIGGVCRQFESALTRIPGSSGQRLADIELLSDEEWDDLVECRNATRAASARQGSL
VDRFAETAAQYADRVAVASGDETLTFRSLSQRSTQFADYLRAQGCEPQAIVALYLRRSPEFVVALLATLKAGAVALPIDP
VLPQARVQHILRDAGASWVVAHADTLGDLPSGSHRVLDVNAPLPPIDPLMSSIPPDAPRSIEDIAYIIYTSGSTGIPKGV
MATHRGLLNRIDAQQEVAPCGPGSIICQKTSVSFVDSVLEILGPVVNGGLLAVMPDDVRSSIAGFVEFLVHRQVTHLVCV
PSLAEALLPEIVRQAPTLKLRYWALSGELLPDELGRALHRILPKCTFVNIYGSSEVAADATFHCFSASQAAPSLIGKPLR
NVAVYVLDATMHPVPAGTWGELYVGGDGLAAGYLGQPELTAAAFLPSPFVPGLRLYRTGDLARWGEGGNLEYMGRVDRQV
KLRGQRIELGEIEAIVGEHPFVREAAVVARPTPTGSLQLNVYVVGKHEETIDVDALRRHLARRIPEAGLQTAIVVLRELP
RTASGKLDYAALPTRTPRPGIKHVAPATANQMRLLDIWQEALKIDGLGIRAGFFDLGGDSLSAMKAVARIAEQWGIRVPL
RAMFEHDTVEEFAQWLEDRLGAERADAQSLAGGGAL

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=634, Percent_Identity=21.7665615141956, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI28416953, Length=509, Percent_Identity=24.5579567779961, Blast_Score=107, Evalue=7e-23,
Organism=Homo sapiens, GI187761345, Length=549, Percent_Identity=22.7686703096539, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI187761343, Length=549, Percent_Identity=22.7686703096539, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI42544132, Length=501, Percent_Identity=22.5548902195609, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI38505220, Length=495, Percent_Identity=24.2424242424242, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI115511026, Length=510, Percent_Identity=22.5490196078431, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI157311624, Length=515, Percent_Identity=23.3009708737864, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI157311622, Length=515, Percent_Identity=23.3009708737864, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI13375727, Length=575, Percent_Identity=22.9565217391304, Blast_Score=74, Evalue=8e-13,
Organism=Escherichia coli, GI1786801, Length=757, Percent_Identity=32.4966974900925, Blast_Score=293, Evalue=4e-80,
Organism=Escherichia coli, GI1788107, Length=551, Percent_Identity=27.4047186932849, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI145693145, Length=542, Percent_Identity=25.830258302583, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1786810, Length=529, Percent_Identity=25.7088846880907, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1790505, Length=361, Percent_Identity=27.4238227146814, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556356, Length=539, Percent_Identity=25.7884972170686, Blast_Score=113, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17560140, Length=517, Percent_Identity=22.6305609284333, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=521, Percent_Identity=21.6890595009597, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560308, Length=527, Percent_Identity=21.6318785578748, Blast_Score=74, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71982997, Length=554, Percent_Identity=24.9097472924188, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983001, Length=554, Percent_Identity=24.9097472924188, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71985884, Length=349, Percent_Identity=22.9226361031519, Blast_Score=71, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=783, Percent_Identity=24.0102171136654, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319699, Length=547, Percent_Identity=22.1206581352834, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323182, Length=532, Percent_Identity=24.2481203007519, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24648676, Length=625, Percent_Identity=30.24, Blast_Score=201, Evalue=2e-51,
Organism=Drosophila melanogaster, GI18859661, Length=508, Percent_Identity=23.4251968503937, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667955, Length=364, Percent_Identity=26.0989010989011, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667959, Length=364, Percent_Identity=26.0989010989011, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI62472339, Length=364, Percent_Identity=26.0989010989011, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24656500, Length=355, Percent_Identity=24.2253521126761, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19922652, Length=527, Percent_Identity=23.9089184060721, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356947, Length=486, Percent_Identity=20.3703703703704, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24581924, Length=542, Percent_Identity=20.6642066420664, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 117632; Mature: 117632

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTKLGPDRVYSPEVNDANTTRLSIAQESFWLLSRHARNDGAFNVSRAWRLRGALDEAAL
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHH
QGAVQDVAHRHDILNSHIEVREDMPYWVYDAGRPLCVECVDLSSSPQSAMDEAFRLVASL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHH
ARNDLDVEAGPLASVTLFRLGRDDHVLLIVLHHLISDAWSIKVFIDEVSQCYSARVNGEV
HHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCEE
VAPGRRPLQYMDYALLQKCNLTTPLFERKAAFWRSRLSDVPAPFSLPARRVVKERGTTTG
ECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCC
AAQQHALSPLVISAVAGWAETRGLSLNMICLAAYAMVMARQSGQSEFMICMPVHCRTKVE
HHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
TKNIIGPVVNPLAIAIRVDQCMTVEDFLSEVRRAVLDAYRHHEYPLERAIRDIKAYGAVS
HHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEE
WQVPFNLFFNFYSEPSATPILSSVTAERLDLGPKGVKFDLSLTVRISHDNSRYCIDYDSS
EECCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEECCCH
LFDAAQIGGVCRQFESALTRIPGSSGQRLADIELLSDEEWDDLVECRNATRAASARQGSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHH
VDRFAETAAQYADRVAVASGDETLTFRSLSQRSTQFADYLRAQGCEPQAIVALYLRRSPE
HHHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
FVVALLATLKAGAVALPIDPVLPQARVQHILRDAGASWVVAHADTLGDLPSGSHRVLDVN
HHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEECHHCCCCCCCCCEEEECC
APLPPIDPLMSSIPPDAPRSIEDIAYIIYTSGSTGIPKGVMATHRGLLNRIDAQQEVAPC
CCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHCCCC
GPGSIICQKTSVSFVDSVLEILGPVVNGGLLAVMPDDVRSSIAGFVEFLVHRQVTHLVCV
CCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
PSLAEALLPEIVRQAPTLKLRYWALSGELLPDELGRALHRILPKCTFVNIYGSSEVAADA
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
TFHCFSASQAAPSLIGKPLRNVAVYVLDATMHPVPAGTWGELYVGGDGLAAGYLGQPELT
EEEECCCCCCCHHHHHCHHHHEEEEEEECCCCCCCCCCCCEEEECCCCCEECCCCCCCHH
AAAFLPSPFVPGLRLYRTGDLARWGEGGNLEYMGRVDRQVKLRGQRIELGEIEAIVGEHP
HHHHCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCEECCCEECCCHHHHHHCCCC
FVREAAVVARPTPTGSLQLNVYVVGKHEETIDVDALRRHLARRIPEAGLQTAIVVLRELP
CHHHHHEEECCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCC
RTASGKLDYAALPTRTPRPGIKHVAPATANQMRLLDIWQEALKIDGLGIRAGFFDLGGDS
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECEEECCCCH
LSAMKAVARIAEQWGIRVPLRAMFEHDTVEEFAQWLEDRLGAERADAQSLAGGGAL
HHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MRTKLGPDRVYSPEVNDANTTRLSIAQESFWLLSRHARNDGAFNVSRAWRLRGALDEAAL
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHH
QGAVQDVAHRHDILNSHIEVREDMPYWVYDAGRPLCVECVDLSSSPQSAMDEAFRLVASL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHH
ARNDLDVEAGPLASVTLFRLGRDDHVLLIVLHHLISDAWSIKVFIDEVSQCYSARVNGEV
HHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCEE
VAPGRRPLQYMDYALLQKCNLTTPLFERKAAFWRSRLSDVPAPFSLPARRVVKERGTTTG
ECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCC
AAQQHALSPLVISAVAGWAETRGLSLNMICLAAYAMVMARQSGQSEFMICMPVHCRTKVE
HHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
TKNIIGPVVNPLAIAIRVDQCMTVEDFLSEVRRAVLDAYRHHEYPLERAIRDIKAYGAVS
HHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEE
WQVPFNLFFNFYSEPSATPILSSVTAERLDLGPKGVKFDLSLTVRISHDNSRYCIDYDSS
EECCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEECCCH
LFDAAQIGGVCRQFESALTRIPGSSGQRLADIELLSDEEWDDLVECRNATRAASARQGSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHH
VDRFAETAAQYADRVAVASGDETLTFRSLSQRSTQFADYLRAQGCEPQAIVALYLRRSPE
HHHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
FVVALLATLKAGAVALPIDPVLPQARVQHILRDAGASWVVAHADTLGDLPSGSHRVLDVN
HHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEECHHCCCCCCCCCEEEECC
APLPPIDPLMSSIPPDAPRSIEDIAYIIYTSGSTGIPKGVMATHRGLLNRIDAQQEVAPC
CCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHCCCC
GPGSIICQKTSVSFVDSVLEILGPVVNGGLLAVMPDDVRSSIAGFVEFLVHRQVTHLVCV
CCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
PSLAEALLPEIVRQAPTLKLRYWALSGELLPDELGRALHRILPKCTFVNIYGSSEVAADA
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
TFHCFSASQAAPSLIGKPLRNVAVYVLDATMHPVPAGTWGELYVGGDGLAAGYLGQPELT
EEEECCCCCCCHHHHHCHHHHEEEEEEECCCCCCCCCCCCEEEECCCCCEECCCCCCCHH
AAAFLPSPFVPGLRLYRTGDLARWGEGGNLEYMGRVDRQVKLRGQRIELGEIEAIVGEHP
HHHHCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCEECCCEECCCHHHHHHCCCC
FVREAAVVARPTPTGSLQLNVYVVGKHEETIDVDALRRHLARRIPEAGLQTAIVVLRELP
CHHHHHEEECCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCC
RTASGKLDYAALPTRTPRPGIKHVAPATANQMRLLDIWQEALKIDGLGIRAGFFDLGGDS
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECEEECCCCH
LSAMKAVARIAEQWGIRVPLRAMFEHDTVEEFAQWLEDRLGAERADAQSLAGGGAL
HHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA