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The map label for this gene is cobL [H]

Identifier: 238027439

GI number: 238027439

Start: 2015095

End: 2016315

Strand: Reverse

Name: cobL [H]

Synonym: bglu_1g18420

Alternate gene names: 238027439

Gene position: 2016315-2015095 (Counterclockwise)

Preceding gene: 238027445

Following gene: 238027438

Centisome position: 51.61

GC content: 77.15

Gene sequence:

>1221_bases
ATGACGGCGTGGCTGACGGTGGTCGGAATCGGTGACGACGGATTCGCGGGGCTCGGCAAGCCCGCACGGCGCGCGCTGAT
CGACGCGGCCGTGGTGATCGGCGGCGAGCGTCACCTGGCGATGCTGCCGGCCCGCCTGCGCGCGCGGCGCGAGCCGTGGC
CGAAGCCGTTCGATCTCGCCGCGCTGCTGGCGCGGCGCGGCGAGGCCGTATGCGTGCTCGCGAGCGGCGACCCGATGTTC
TACGGTGTCGGCGCGACGCTCGCGCGGCAACTGCCGGCAGAGGAGCTGCGCGTGCTGCCGGCGCCGTCGTCGGCCTCGCT
GGCCGCGGCGCGGCTCGGCTGGGCGCTGCACGACTTGGAGGTCGTGTCGTGCGTCGGCCGTCCGCTCGCGGCGCTCGCGC
GCCATCTGCATCATGGCCGGCGCCTGCTGGTGCTGAGCGCCGACGGCGCGACGCCGGCCGCGCTGGCGGCGCTGCTGGCC
GAGGCCGGCTACGGCGCGACGCGCATGAGCGTGTTCGAGCATCTGGGCGGGCCCGACGAGCGCCGCATCGACGCGCTCGC
GCGGGCCTGGCCCATGGCGCGCGTCGCCGCGCTGAACCTGATCGCGCTCGACTGCGCACGCGCGGCCGACACGCCCCCCG
TGCCGCTCACGCCGGGCCTGCCCGACGATGCCTACCAGCACGACGGCCAGCTGACCAAGCGCGACATGCGCGCGATCACG
CTGGGGCGGCTCGCGCCGACCCCGGGCGAGTTGCTGTGGGACGTGGGCGCGGGCTCCGGCTCGATCGGCATCGAATGGAT
GCGCGCGCATCCGTCCTGCATGGCGCTCGCCATCGAGGCCGACGCGGCGCGCCGCCAGACCATCGCGCTGAACCGCGACC
GGCTCGGCGTGCCGGGGCTCGCGATCGTGGCGGGCCGCGCGCCCGAGGCGCTCGCCGGGCTCGCCGCGCCCGACGCGGTG
TTCGTCGGCGGCGGGGGCAGCGAGCCCGGCGTGCTGGCCGCCTGCTGGGCCGCGCTGAAGCCGGGCGGGCGGCTGGTGGC
CAACGCGGTGACGCTGCAGGCCGAGGCGGCGCTGCTCGACTGGCGCGACCGCCACGGCGGCACGCTCACGCGCGTCGCGC
TCGCCGGCGCGGCGCCGCTGGGCGGCTTCGATACCTGGCGCCCGGCCTTGCCCGTCACGCTCTACGAGGTCCGCAAGCCG
CTTGCGGAAGGCGGCGCATGA

Upstream 100 bases:

>100_bases
CTGCTTTCGTTCGGCCGAGATACGCCGCGCGCGCCGCTCGGGCGCGCCCGAGCGGCGGCCGGCAACGCGGCGAGGGTGGG
GCACGGATGGGGAACGGGGC

Downstream 100 bases:

>100_bases
GCGGCACCGCGCCCGCCACCGCCCGCGCCGCCGCGCGCGTGCTGCTGCTCGGCGGCACCGGCGACGCGCTGGCGATCGCG
CGCACGCTGCCGGCCGGCGA

Product: precorrin-6y C5,15-methyltransferase, subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTAWLTVVGIGDDGFAGLGKPARRALIDAAVVIGGERHLAMLPARLRARREPWPKPFDLAALLARRGEAVCVLASGDPMF
YGVGATLARQLPAEELRVLPAPSSASLAAARLGWALHDLEVVSCVGRPLAALARHLHHGRRLLVLSADGATPAALAALLA
EAGYGATRMSVFEHLGGPDERRIDALARAWPMARVAALNLIALDCARAADTPPVPLTPGLPDDAYQHDGQLTKRDMRAIT
LGRLAPTPGELLWDVGAGSGSIGIEWMRAHPSCMALAIEADAARRQTIALNRDRLGVPGLAIVAGRAPEALAGLAAPDAV
FVGGGGSEPGVLAACWAALKPGGRLVANAVTLQAEAALLDWRDRHGGTLTRVALAGAAPLGGFDTWRPALPVTLYEVRKP
LAEGGA

Sequences:

>Translated_406_residues
MTAWLTVVGIGDDGFAGLGKPARRALIDAAVVIGGERHLAMLPARLRARREPWPKPFDLAALLARRGEAVCVLASGDPMF
YGVGATLARQLPAEELRVLPAPSSASLAAARLGWALHDLEVVSCVGRPLAALARHLHHGRRLLVLSADGATPAALAALLA
EAGYGATRMSVFEHLGGPDERRIDALARAWPMARVAALNLIALDCARAADTPPVPLTPGLPDDAYQHDGQLTKRDMRAIT
LGRLAPTPGELLWDVGAGSGSIGIEWMRAHPSCMALAIEADAARRQTIALNRDRLGVPGLAIVAGRAPEALAGLAAPDAV
FVGGGGSEPGVLAACWAALKPGGRLVANAVTLQAEAALLDWRDRHGGTLTRVALAGAAPLGGFDTWRPALPVTLYEVRKP
LAEGGA
>Mature_405_residues
TAWLTVVGIGDDGFAGLGKPARRALIDAAVVIGGERHLAMLPARLRARREPWPKPFDLAALLARRGEAVCVLASGDPMFY
GVGATLARQLPAEELRVLPAPSSASLAAARLGWALHDLEVVSCVGRPLAALARHLHHGRRLLVLSADGATPAALAALLAE
AGYGATRMSVFEHLGGPDERRIDALARAWPMARVAALNLIALDCARAADTPPVPLTPGLPDDAYQHDGQLTKRDMRAITL
GRLAPTPGELLWDVGAGSGSIGIEWMRAHPSCMALAIEADAARRQTIALNRDRLGVPGLAIVAGRAPEALAGLAAPDAVF
VGGGGSEPGVLAACWAALKPGGRLVANAVTLQAEAALLDWRDRHGGTLTRVALAGAAPLGGFDTWRPALPVTLYEVRKPL
AEGGA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 42174; Mature: 42043

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWLTVVGIGDDGFAGLGKPARRALIDAAVVIGGERHLAMLPARLRARREPWPKPFDLA
CCEEEEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCCEECCCHHHHHCCCCCCCCHHHH
ALLARRGEAVCVLASGDPMFYGVGATLARQLPAEELRVLPAPSSASLAAARLGWALHDLE
HHHHCCCCEEEEEECCCCEEEECHHHHHHHCCHHHHEEECCCCCCHHHHHHHHHHHHHHH
VVSCVGRPLAALARHLHHGRRLLVLSADGATPAALAALLAEAGYGATRMSVFEHLGGPDE
HHHHCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCH
RRIDALARAWPMARVAALNLIALDCARAADTPPVPLTPGLPDDAYQHDGQLTKRDMRAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHE
LGRLAPTPGELLWDVGAGSGSIGIEWMRAHPSCMALAIEADAARRQTIALNRDRLGVPGL
ECCCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEEEECCCHHCCEEEECCCCCCCCCE
AIVAGRAPEALAGLAAPDAVFVGGGGSEPGVLAACWAALKPGGRLVANAVTLQAEAALLD
EEEECCCCHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEHHHHHHC
WRDRHGGTLTRVALAGAAPLGGFDTWRPALPVTLYEVRKPLAEGGA
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAWLTVVGIGDDGFAGLGKPARRALIDAAVVIGGERHLAMLPARLRARREPWPKPFDLA
CEEEEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCCEECCCHHHHHCCCCCCCCHHHH
ALLARRGEAVCVLASGDPMFYGVGATLARQLPAEELRVLPAPSSASLAAARLGWALHDLE
HHHHCCCCEEEEEECCCCEEEECHHHHHHHCCHHHHEEECCCCCCHHHHHHHHHHHHHHH
VVSCVGRPLAALARHLHHGRRLLVLSADGATPAALAALLAEAGYGATRMSVFEHLGGPDE
HHHHCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCH
RRIDALARAWPMARVAALNLIALDCARAADTPPVPLTPGLPDDAYQHDGQLTKRDMRAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHE
LGRLAPTPGELLWDVGAGSGSIGIEWMRAHPSCMALAIEADAARRQTIALNRDRLGVPGL
ECCCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEEEECCCHHCCEEEECCCCCCCCCE
AIVAGRAPEALAGLAAPDAVFVGGGGSEPGVLAACWAALKPGGRLVANAVTLQAEAALLD
EEEECCCCHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEHHHHHHC
WRDRHGGTLTRVALAGAAPLGGFDTWRPALPVTLYEVRKPLAEGGA
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]