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The map label for this gene is ynfJ [C]

Identifier: 238027233

GI number: 238027233

Start: 1775478

End: 1777211

Strand: Reverse

Name: ynfJ [C]

Synonym: bglu_1g16190

Alternate gene names: 238027233

Gene position: 1777211-1775478 (Counterclockwise)

Preceding gene: 238027234

Following gene: 238027231

Centisome position: 45.49

GC content: 70.76

Gene sequence:

>1734_bases
GTGCTGTCCTTTCTGCTGAAGCTGCGCACCCGCGCACAAACGCTGTTCCGCCTGTCGGACGCCCATACCATGCTGATCTG
GTCGGTGATCGCCGGCATCAGCGGCGCGTTCGCGACGATCCTGTTCCGCGAGGGCATCGACACGATCCAGCGGCTGGTGT
CCGGCTCGTCCGGCAGCTTCGTCGAGATGGCCAAGCGCCTGCCGTGGCAGACCCGGGTCTGGCTGCCCGCCGCGGGCGGC
TTCCTGGCCGGCTGCGTGCTGCTGGCCGCGCAGCGCGGCCAGGCCAGGAAACCGGGTGCCGACTACATGGAGGCGGTGGC
GCTCGGCGACGGCGTGGTGCCGGTCGGGGAAAGCCTGTGGCGCAGCGCGTCGTCGCTGCTGACGATCGGCAGCGGCGGCT
CGATTGGCCGCGAAGGGCCGATGGTCCAGCTCGCCGCGCTGGCCGCCTCGCTGGTCGGGCGCCTCGCGCGCTTCGATCCG
CCGCGCCTGCGCCTGCTGGTGGCCTGCGGCGCCGCGGCCGGCATCACCTCGGCCTACAACGCGCCGATCGCCGGCGCGTT
CTTCGTCGGCGAGATCGTGCTCGGCGCGATCGCGATGGAAAGCTTCGGACCGATGCTGGTGGCCTCGGTGGTGGCCAACA
TCACGATGCGCGAATTCGCCGGCTACCGCCCCCCCTACGAGATGCCGGTGTTCCCGGCCGTGACGGGCCTCGAGGTGCTC
GCGTTCGTCGCGCTCGGCCTGCTCTGCGGCGCGGCCGCGCCGCAGTTCCTGCGCCTGCTGGCCGCCTCGAAGGCGCGCTT
TCGCCAGTTGCCCGCGCCGCTGCCGGTGCGGCTCGCACTAGGCGGGCTGGTGGTCGGCGTGATCTCGGTGTGGGTGCCCG
ACGTCTGGGGCAACGGCTACAGCGTGGTCAACTCGATCCTGCACACGCCGTGGACCTGGCAGGCGCTCGTCGTGGTGCTC
GCATTCAAGCTGCTGGCCACCGCCGCCACCTCGGGCTCGGGCGCGGTGGGCGGGATCTTCACGCCCACGCTGTTCGTCGG
CGCCACGGCGGGCGCCTTGTTCGGCCTCGCCATGCAGGCGCTGCTGCCGGGCCACGTGTCGGCCTCGTACGCCTACGCGA
TAGTCGGGATGGGCGCGTTCCTGGCCGGCGCGACGCAGGCGCCGCTGATGGCGATCCTGATGATCTTCGAGATGACGCTG
AGCTACCAGGTGGTGCTGCCGCTGATGGTGTCGTGCGTGGTGGCCTACTTCGGCGCGCGCGCGCTCGGCCGCACCTCGAT
GTACGAGATCACGCTGCGCCGCCATCGCGACGAGGAAGAACGGCTGCGGCTGCGCGCCACCCAGATGCGCGCGCTGATCC
AGCCCGCGCAGACGGTGGTGCGGCCCGACGCGAGCGTGGCCGAAATGGCGCGCGTGTTCCTCGAGTATCCGGTCAAATAC
CTTTATGTGACCGACCACGACGGCCGCTTTCGCGGCGCGGTGGCGCTGAAGGACATCACCTCGGACCTGCTGGAAGGCCA
GGACACGCAGCACCGCACGGCCGCCAGCTATGCCCACACGCCGTTCCCGCTGCTCACGCCGGACATGGCGCTCGGCGCCG
CCTTCGAGCACTTCATGAACTTTCAGGGCGAACGGCTGCCGGTGGTGGAGAGCCTCGCGGAGCCGGTGCTGGCGGGAGTG
GTCTACAAGACCTCGCTGCTCGACGCATACCGGCGCATGAACGCGAGCCGCTGA

Upstream 100 bases:

>100_bases
GCCCCCGGACCGCCTTCCCCGCCCCGCGCCGCGCCCGCCTCCCCGGGCGGGCGCGGCGCGGTGCTATGCTTGCGGTCGAC
TTTCTCCGCCCGCCGACCCC

Downstream 100 bases:

>100_bases
GACGGCGCGGGCAGGCCGCGGGGCAACAGGCGCGCACGCCCAGGAAGCAGCAAGGAAGCCGCGAAGAAACGACCAGCAAC
AGCCGCAAGGACGCGGCGGG

Product: putative voltage-gated ClC-type chloride channel ClcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MLSFLLKLRTRAQTLFRLSDAHTMLIWSVIAGISGAFATILFREGIDTIQRLVSGSSGSFVEMAKRLPWQTRVWLPAAGG
FLAGCVLLAAQRGQARKPGADYMEAVALGDGVVPVGESLWRSASSLLTIGSGGSIGREGPMVQLAALAASLVGRLARFDP
PRLRLLVACGAAAGITSAYNAPIAGAFFVGEIVLGAIAMESFGPMLVASVVANITMREFAGYRPPYEMPVFPAVTGLEVL
AFVALGLLCGAAAPQFLRLLAASKARFRQLPAPLPVRLALGGLVVGVISVWVPDVWGNGYSVVNSILHTPWTWQALVVVL
AFKLLATAATSGSGAVGGIFTPTLFVGATAGALFGLAMQALLPGHVSASYAYAIVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMVSCVVAYFGARALGRTSMYEITLRRHRDEEERLRLRATQMRALIQPAQTVVRPDASVAEMARVFLEYPVKY
LYVTDHDGRFRGAVALKDITSDLLEGQDTQHRTAASYAHTPFPLLTPDMALGAAFEHFMNFQGERLPVVESLAEPVLAGV
VYKTSLLDAYRRMNASR

Sequences:

>Translated_577_residues
MLSFLLKLRTRAQTLFRLSDAHTMLIWSVIAGISGAFATILFREGIDTIQRLVSGSSGSFVEMAKRLPWQTRVWLPAAGG
FLAGCVLLAAQRGQARKPGADYMEAVALGDGVVPVGESLWRSASSLLTIGSGGSIGREGPMVQLAALAASLVGRLARFDP
PRLRLLVACGAAAGITSAYNAPIAGAFFVGEIVLGAIAMESFGPMLVASVVANITMREFAGYRPPYEMPVFPAVTGLEVL
AFVALGLLCGAAAPQFLRLLAASKARFRQLPAPLPVRLALGGLVVGVISVWVPDVWGNGYSVVNSILHTPWTWQALVVVL
AFKLLATAATSGSGAVGGIFTPTLFVGATAGALFGLAMQALLPGHVSASYAYAIVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMVSCVVAYFGARALGRTSMYEITLRRHRDEEERLRLRATQMRALIQPAQTVVRPDASVAEMARVFLEYPVKY
LYVTDHDGRFRGAVALKDITSDLLEGQDTQHRTAASYAHTPFPLLTPDMALGAAFEHFMNFQGERLPVVESLAEPVLAGV
VYKTSLLDAYRRMNASR
>Mature_577_residues
MLSFLLKLRTRAQTLFRLSDAHTMLIWSVIAGISGAFATILFREGIDTIQRLVSGSSGSFVEMAKRLPWQTRVWLPAAGG
FLAGCVLLAAQRGQARKPGADYMEAVALGDGVVPVGESLWRSASSLLTIGSGGSIGREGPMVQLAALAASLVGRLARFDP
PRLRLLVACGAAAGITSAYNAPIAGAFFVGEIVLGAIAMESFGPMLVASVVANITMREFAGYRPPYEMPVFPAVTGLEVL
AFVALGLLCGAAAPQFLRLLAASKARFRQLPAPLPVRLALGGLVVGVISVWVPDVWGNGYSVVNSILHTPWTWQALVVVL
AFKLLATAATSGSGAVGGIFTPTLFVGATAGALFGLAMQALLPGHVSASYAYAIVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMVSCVVAYFGARALGRTSMYEITLRRHRDEEERLRLRATQMRALIQPAQTVVRPDASVAEMARVFLEYPVKY
LYVTDHDGRFRGAVALKDITSDLLEGQDTQHRTAASYAHTPFPLLTPDMALGAAFEHFMNFQGERLPVVESLAEPVLAGV
VYKTSLLDAYRRMNASR

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI153252026, Length=446, Percent_Identity=23.7668161434978, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI55770840, Length=382, Percent_Identity=24.0837696335079, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI55770838, Length=382, Percent_Identity=24.0837696335079, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI87081943, Length=426, Percent_Identity=39.2018779342723, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1786350, Length=316, Percent_Identity=27.2151898734177, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17532615, Length=354, Percent_Identity=24.2937853107345, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 61553; Mature: 61553

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFLLKLRTRAQTLFRLSDAHTMLIWSVIAGISGAFATILFREGIDTIQRLVSGSSGSF
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VEMAKRLPWQTRVWLPAAGGFLAGCVLLAAQRGQARKPGADYMEAVALGDGVVPVGESLW
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
RSASSLLTIGSGGSIGREGPMVQLAALAASLVGRLARFDPPRLRLLVACGAAAGITSAYN
HCHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEHEECCCHHCCCHHCC
APIAGAFFVGEIVLGAIAMESFGPMLVASVVANITMREFAGYRPPYEMPVFPAVTGLEVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
AFVALGLLCGAAAPQFLRLLAASKARFRQLPAPLPVRLALGGLVVGVISVWVPDVWGNGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
SVVNSILHTPWTWQALVVVLAFKLLATAATSGSGAVGGIFTPTLFVGATAGALFGLAMQA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLPGHVSASYAYAIVGMGAFLAGATQAPLMAILMIFEMTLSYQVVLPLMVSCVVAYFGAR
HCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGRTSMYEITLRRHRDEEERLRLRATQMRALIQPAQTVVRPDASVAEMARVFLEYPVKY
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEE
LYVTDHDGRFRGAVALKDITSDLLEGQDTQHRTAASYAHTPFPLLTPDMALGAAFEHFMN
EEEECCCCCEEHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
FQGERLPVVESLAEPVLAGVVYKTSLLDAYRRMNASR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSFLLKLRTRAQTLFRLSDAHTMLIWSVIAGISGAFATILFREGIDTIQRLVSGSSGSF
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VEMAKRLPWQTRVWLPAAGGFLAGCVLLAAQRGQARKPGADYMEAVALGDGVVPVGESLW
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
RSASSLLTIGSGGSIGREGPMVQLAALAASLVGRLARFDPPRLRLLVACGAAAGITSAYN
HCHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEHEECCCHHCCCHHCC
APIAGAFFVGEIVLGAIAMESFGPMLVASVVANITMREFAGYRPPYEMPVFPAVTGLEVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
AFVALGLLCGAAAPQFLRLLAASKARFRQLPAPLPVRLALGGLVVGVISVWVPDVWGNGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
SVVNSILHTPWTWQALVVVLAFKLLATAATSGSGAVGGIFTPTLFVGATAGALFGLAMQA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLPGHVSASYAYAIVGMGAFLAGATQAPLMAILMIFEMTLSYQVVLPLMVSCVVAYFGAR
HCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGRTSMYEITLRRHRDEEERLRLRATQMRALIQPAQTVVRPDASVAEMARVFLEYPVKY
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEE
LYVTDHDGRFRGAVALKDITSDLLEGQDTQHRTAASYAHTPFPLLTPDMALGAAFEHFMN
EEEECCCCCEEHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
FQGERLPVVESLAEPVLAGVVYKTSLLDAYRRMNASR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]