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The map label for this gene is blh [H]

Identifier: 238027227

GI number: 238027227

Start: 1765899

End: 1766801

Strand: Reverse

Name: blh [H]

Synonym: bglu_1g16130

Alternate gene names: 238027227

Gene position: 1766801-1765899 (Counterclockwise)

Preceding gene: 238027229

Following gene: 238027226

Centisome position: 45.23

GC content: 71.43

Gene sequence:

>903_bases
ATGACGTCCCAACCCGCCTTCACCGTCGATTCGTTCTTCGACCCGGCCACCAATACGGCCACGCACGTCGTGGTCGACAC
CGCCACGCGCGAGTGCGCGATCGTCGACCCCGTGCTCGATTTCGATCCGAAGTCCGGCCGCACCCACCACCGCAGCGCCG
AGCGCGTCGCCGCGCAGGTGGAGGCACTCGGCGCGCGCGTGCGCTGGCTGCTGGAAACCCATGTGCACGCCGACCACCTC
TCGGCCGCGCCGCTGCTGCAGGCGCGCTTGGGCGGCGAGATCGCGATCGGCCGCGAGGTCACGCAGGTACAGAAGGTGTT
CGGCACGCTGTTCGACGCCGGCCCGGACTTCGTGCCGGACGGCCGCCCGTTCGACCGGCTCGTCGACGACGGCGACACGC
TCGCGCTCGGCAGGCTCGCGATCCGCGCGATGCATACGCCCGGCCACACGCCGGCCTGCATGACCTACCTGGTGGCGCGC
GCGGATGGCACCTCGGCGCCGGCCGAGACGGCCGCGTTCGTCGGCGACACGCTGTTCATGCCCGACTACGGCACCGCGCG
CTGCGACTTCCCCGGCGGCGACGCGCGCACGCTCTACCGCTCGATCCGCAAGGTGCTGAGCCTGCCGCCCGACACGCCGC
TCTATCTGTGCCACGACTACGCGCCCCAGGGCCGACCGGTCTGCCTCGTCACCACCGTGGGCGCACAGCGGCGCGACAAC
ATCCACGTCCACGAGGGAATCGACGAGGACACGTTCGTGGCGATGCGTACCGCGCGCGATGCGACGCTGGAGATGCCGGT
GCTGATCCTGCCGTCGGTGCAGGTCAACATGCGCGCGGGGCGGCTGCCGGAGCCCGCGGCCAACGGGGTGCGCTACCTGA
AGCTGCCGATCGACGCGCTCTAA

Upstream 100 bases:

>100_bases
CGGATCAATTGATTAAGCGATACGCGCGCGCCGTGCACGACGCTGGCACGCATCTTGTCTCGCTCAGGCGTTTTCCCGAT
TTCTGATTCCGGAGCATTGC

Downstream 100 bases:

>100_bases
GGCGCCGCCCGCGCCGCCGGGCAGCGCCGCTTCGCTGCACCACCACAACAACGCCATCAAGCATATCCCCTGCCAGGAGC
CCCAACATGTCCGTCCCGTC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTSQPAFTVDSFFDPATNTATHVVVDTATRECAIVDPVLDFDPKSGRTHHRSAERVAAQVEALGARVRWLLETHVHADHL
SAAPLLQARLGGEIAIGREVTQVQKVFGTLFDAGPDFVPDGRPFDRLVDDGDTLALGRLAIRAMHTPGHTPACMTYLVAR
ADGTSAPAETAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIRKVLSLPPDTPLYLCHDYAPQGRPVCLVTTVGAQRRDN
IHVHEGIDEDTFVAMRTARDATLEMPVLILPSVQVNMRAGRLPEPAANGVRYLKLPIDAL

Sequences:

>Translated_300_residues
MTSQPAFTVDSFFDPATNTATHVVVDTATRECAIVDPVLDFDPKSGRTHHRSAERVAAQVEALGARVRWLLETHVHADHL
SAAPLLQARLGGEIAIGREVTQVQKVFGTLFDAGPDFVPDGRPFDRLVDDGDTLALGRLAIRAMHTPGHTPACMTYLVAR
ADGTSAPAETAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIRKVLSLPPDTPLYLCHDYAPQGRPVCLVTTVGAQRRDN
IHVHEGIDEDTFVAMRTARDATLEMPVLILPSVQVNMRAGRLPEPAANGVRYLKLPIDAL
>Mature_299_residues
TSQPAFTVDSFFDPATNTATHVVVDTATRECAIVDPVLDFDPKSGRTHHRSAERVAAQVEALGARVRWLLETHVHADHLS
AAPLLQARLGGEIAIGREVTQVQKVFGTLFDAGPDFVPDGRPFDRLVDDGDTLALGRLAIRAMHTPGHTPACMTYLVARA
DGTSAPAETAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIRKVLSLPPDTPLYLCHDYAPQGRPVCLVTTVGAQRRDNI
HVHEGIDEDTFVAMRTARDATLEMPVLILPSVQVNMRAGRLPEPAANGVRYLKLPIDAL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=271, Percent_Identity=30.9963099630996, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI94538320, Length=205, Percent_Identity=28.780487804878, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI94538322, Length=205, Percent_Identity=28.780487804878, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI116642887, Length=207, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI21703352, Length=207, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787158, Length=214, Percent_Identity=28.0373831775701, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=266, Percent_Identity=26.6917293233083, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI221330176, Length=277, Percent_Identity=28.5198555956679, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32541; Mature: 32410

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQPAFTVDSFFDPATNTATHVVVDTATRECAIVDPVLDFDPKSGRTHHRSAERVAAQV
CCCCCCEEHHHCCCCCCCCEEEEEEECCCCCEEEECCHHCCCCCCCCCHHHHHHHHHHHH
EALGARVRWLLETHVHADHLSAAPLLQARLGGEIAIGREVTQVQKVFGTLFDAGPDFVPD
HHHHHHHHHHHHHHCCHHHHCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCCCCC
GRPFDRLVDDGDTLALGRLAIRAMHTPGHTPACMTYLVARADGTSAPAETAAFVGDTLFM
CCCHHHHHCCCCEEEHHHHHHEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCEEEC
PDYGTARCDFPGGDARTLYRSIRKVLSLPPDTPLYLCHDYAPQGRPVCLVTTVGAQRRDN
CCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCC
IHVHEGIDEDTFVAMRTARDATLEMPVLILPSVQVNMRAGRLPEPAANGVRYLKLPIDAL
EEEECCCCCCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TSQPAFTVDSFFDPATNTATHVVVDTATRECAIVDPVLDFDPKSGRTHHRSAERVAAQV
CCCCCEEHHHCCCCCCCCEEEEEEECCCCCEEEECCHHCCCCCCCCCHHHHHHHHHHHH
EALGARVRWLLETHVHADHLSAAPLLQARLGGEIAIGREVTQVQKVFGTLFDAGPDFVPD
HHHHHHHHHHHHHHCCHHHHCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCCCCC
GRPFDRLVDDGDTLALGRLAIRAMHTPGHTPACMTYLVARADGTSAPAETAAFVGDTLFM
CCCHHHHHCCCCEEEHHHHHHEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCEEEC
PDYGTARCDFPGGDARTLYRSIRKVLSLPPDTPLYLCHDYAPQGRPVCLVTTVGAQRRDN
CCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCC
IHVHEGIDEDTFVAMRTARDATLEMPVLILPSVQVNMRAGRLPEPAANGVRYLKLPIDAL
EEEECCCCCCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]