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The map label for this gene is pyrH [H]

Identifier: 238026904

GI number: 238026904

Start: 1397478

End: 1398257

Strand: Direct

Name: pyrH [H]

Synonym: bglu_1g12740

Alternate gene names: 238026904

Gene position: 1397478-1398257 (Clockwise)

Preceding gene: 238026903

Following gene: 238026905

Centisome position: 35.77

GC content: 65.77

Gene sequence:

>780_bases
TTGCCCGAATCAGTATTTCGCCCCTACAGTTCGTGGTTGTCATCCTTTCGTCGCTTGGAAGCCTCTATGCCCAATGCCTA
TAAACGCATCCTCCTCAAACTTTCCGGCGAAGCGCTGATGGGCGACGATGCCTTCGGCATCAACCGCGCGACGATCGAAC
GGATGGTGGCGGACATTGCCGAAGTGGTGCGGCTCGGCACGCAGCTGGCCGTGGTGATCGGCGGCGGCAATATTTTCCGC
GGCGTGGCGGGCGGCGCGGCCGGCATGGACCGCGCGACGGCGGACTACATGGGGATGCTGGCCACCATGATGAACGCGCT
GGCGCTGCAGGACGCGATGCGCCACGCCGGCATCGAGGCGCGCGTGCAGTCGGCGCTGCGCATGGACCAGGTGGTCGAGC
CGTACATCCGGCCCCGCGCGATCCGTCAGCTCGAGGAAGGGCGCGTGGTGATCTTCGCCGCCGGCACCGGCAACCCGTTC
TTCACGACCGACACGGCCGCCGCGCTGCGCGGCTCGGAAGTCGGGGCCGAGGTCGTGCTGAAGGCCACCAAGGTCGATGG
CGTCTACACGGCCGACCCGAAGAAGGACCCGTCGGCCACGCGCTATGCATCGATCAGCTTCGATGAGGCGATCGGCCGCA
ATCTGCAGGTGATGGACGCGACGGCGTTCGCGCTGTGCCGCGACCAGAAGCTGCCGATCCGCGTGTTCTCGATCAACAAG
CCCGGTGCACTCAAGCGCATCGTGCAGGGTGAGGACGAGGGTACGCTCGTTCACGTGTAA

Upstream 100 bases:

>100_bases
CCGTCAGCAGCAAGGTTGGACCCGCGGCGGGCGCTCGCTCCGCCGCGGTTCGGCAGCGCCGCGCGCCGCGGCCTTCGCGG
GCCGCGCAATTTGGCGGCGC

Downstream 100 bases:

>100_bases
ACTCACGCCGATTCGGGCCCGGCATGACGCCGTCGGCGGGATGCGGGCCTGTGTCTTTTCGAAGGTTCGAAGGTTCGGAG
GTTGAAATGAGTGTCGCTGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MPESVFRPYSSWLSSFRRLEASMPNAYKRILLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFR
GVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGRVVIFAAGTGNPF
FTTDTAAALRGSEVGAEVVLKATKVDGVYTADPKKDPSATRYASISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINK
PGALKRIVQGEDEGTLVHV

Sequences:

>Translated_259_residues
MPESVFRPYSSWLSSFRRLEASMPNAYKRILLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFR
GVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGRVVIFAAGTGNPF
FTTDTAAALRGSEVGAEVVLKATKVDGVYTADPKKDPSATRYASISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINK
PGALKRIVQGEDEGTLVHV
>Mature_258_residues
PESVFRPYSSWLSSFRRLEASMPNAYKRILLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRG
VAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGRVVIFAAGTGNPFF
TTDTAAALRGSEVGAEVVLKATKVDGVYTADPKKDPSATRYASISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKP
GALKRIVQGEDEGTLVHV

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=58.8744588744589, Blast_Score=283, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27985; Mature: 27853

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESVFRPYSSWLSSFRRLEASMPNAYKRILLKLSGEALMGDDAFGINRATIERMVADIA
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH
EVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEA
HHHHCCCEEEEEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RVQSALRMDQVVEPYIRPRAIRQLEEGRVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVL
HHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEECCCCCCEECCHHHHHCCCCCCHHHEE
KATKVDGVYTADPKKDPSATRYASISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINK
EEEECCCEEECCCCCCCCCCEEEECCHHHHHCCCEEEEHHHHHHHHCCCCCCEEEEEECC
PGALKRIVQGEDEGTLVHV
CHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure 
PESVFRPYSSWLSSFRRLEASMPNAYKRILLKLSGEALMGDDAFGINRATIERMVADIA
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH
EVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEA
HHHHCCCEEEEEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RVQSALRMDQVVEPYIRPRAIRQLEEGRVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVL
HHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEECCCCCCEECCHHHHHCCCCCCHHHEE
KATKVDGVYTADPKKDPSATRYASISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINK
EEEECCCEEECCCCCCCCCCEEEECCHHHHHCCCEEEEHHHHHHHHCCCCCCEEEEEECC
PGALKRIVQGEDEGTLVHV
CHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA