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The map label for this gene is dapE [H]

Identifier: 238026890

GI number: 238026890

Start: 1376980

End: 1378119

Strand: Reverse

Name: dapE [H]

Synonym: bglu_1g12580

Alternate gene names: 238026890

Gene position: 1378119-1376980 (Counterclockwise)

Preceding gene: 238026891

Following gene: 238026889

Centisome position: 35.28

GC content: 69.21

Gene sequence:

>1140_bases
ATGTCCGCCACCCTTGCCCTTACCGAACAGCTGATCGCCCGCGCGTCGGTGACGCCCGACGACCAGCACTGCCAGCAGAT
CATGATCGAGCGCCTCGCCGCGATCGGCTTCGACTGCGAGACCCTCGCTTCAAACGGCGTGACCAATCTGTGGGCCGTCA
GGCGCGGCAGCGCCGGCCGCGACGGCAAGCTGCTCGCGTTCGCGGGCCACACCGACGTGGTGCCGACCGGCCCGCTCGAA
CAGTGGAGCTCGCCGCCCTTCGTCCCCGCGCATCGCGACGGCAGGCTCTACGGCCGCGGTGCGGCCGACATGAAGACCTC
GCTGGCCGGCTTCGTGGTGGCAAGCGAGGAGTTCGTGGCCGCCCACCCGGACCATCGCGGCTCGATCGCGATGCTGATCA
CGAGCGACGAGGAAGGCCCCGCCACCGACGGCACCGTCAAGGTGATCGAGGCGCTCGCCGCGCGCGGCGAGCGCCTCGAC
TACTGCATCGTCGGCGAGCCGACCTCGTCGGCCACGCTCGGCGACATGGTCAAGAACGGCCGGCGCGGCTCGATGTCGGG
CGAACTCGTCGTGAAGGGCGTGCAAGGCCACATCGCCTATCCGCATCTGGCGAAGAATCCGATCCACCTGCTCGCGCCGG
CGCTGGCCGAACTGGCCGCCGAACGCTGGGACGACGGCAACGAGTATTTCCCGCCCACCACCTGGCAGGTCTCGAACCTG
CACGGCGGCACCGGCGCGACCAACGTGATTCCCGGCCACGTCACGCTGCTGTTCAACTTCCGCTTCTCGACCGCGAGCAC
GGTGGACGGGCTCAAGGCGCGTGTCCACGCGATCCTCGACCGGCACGGCTTCGAATACGCGCTGACCTGGTCGGTCAGCG
GGCTGCCGTTCCTGACGCCGCGCGGCGAGCTGTCGGACGCGCTGGAGCGGGCGATCCTCGCCGAAACCGGCGTGGTGACC
GAGCTGTCGACCACGGGCGGGACCTCCGACGGCCGCTTCATCGCGCGGATCTGCCCGCAGGTGATCGAGTTCGGCCCGCC
CAACGGCTCGATCCACAAGATCGACGAGCACATCGAGCTGCGCTTCGTCGACCCGCTCAAGAACGTGTACCGCCGCGTGC
TCGAACAACTGATCGCCTGA

Upstream 100 bases:

>100_bases
TAGGCCGGCGGCGCGGCGCGCGCGACACCCGGCGCGCCGCTGCGCCACCCCGCCCTGCCGGCCGCCGCGCCGGCATTTTT
CATCGAAAGTGGTCCGAACC

Downstream 100 bases:

>100_bases
CGGAGCCGCCATGACGACCCCCACGCCCACCACGCCGTTCCAGACCGTCCGCGACCTGGTCCGCTATGCGGTGACGCGCT
TCTCGGCCGCGCAGCTCGCG

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSATLALTEQLIARASVTPDDQHCQQIMIERLAAIGFDCETLASNGVTNLWAVRRGSAGRDGKLLAFAGHTDVVPTGPLE
QWSSPPFVPAHRDGRLYGRGAADMKTSLAGFVVASEEFVAAHPDHRGSIAMLITSDEEGPATDGTVKVIEALAARGERLD
YCIVGEPTSSATLGDMVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAERWDDGNEYFPPTTWQVSNL
HGGTGATNVIPGHVTLLFNFRFSTASTVDGLKARVHAILDRHGFEYALTWSVSGLPFLTPRGELSDALERAILAETGVVT
ELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIELRFVDPLKNVYRRVLEQLIA

Sequences:

>Translated_379_residues
MSATLALTEQLIARASVTPDDQHCQQIMIERLAAIGFDCETLASNGVTNLWAVRRGSAGRDGKLLAFAGHTDVVPTGPLE
QWSSPPFVPAHRDGRLYGRGAADMKTSLAGFVVASEEFVAAHPDHRGSIAMLITSDEEGPATDGTVKVIEALAARGERLD
YCIVGEPTSSATLGDMVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAERWDDGNEYFPPTTWQVSNL
HGGTGATNVIPGHVTLLFNFRFSTASTVDGLKARVHAILDRHGFEYALTWSVSGLPFLTPRGELSDALERAILAETGVVT
ELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIELRFVDPLKNVYRRVLEQLIA
>Mature_378_residues
SATLALTEQLIARASVTPDDQHCQQIMIERLAAIGFDCETLASNGVTNLWAVRRGSAGRDGKLLAFAGHTDVVPTGPLEQ
WSSPPFVPAHRDGRLYGRGAADMKTSLAGFVVASEEFVAAHPDHRGSIAMLITSDEEGPATDGTVKVIEALAARGERLDY
CIVGEPTSSATLGDMVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAERWDDGNEYFPPTTWQVSNLH
GGTGATNVIPGHVTLLFNFRFSTASTVDGLKARVHAILDRHGFEYALTWSVSGLPFLTPRGELSDALERAILAETGVVTE
LSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIELRFVDPLKNVYRRVLEQLIA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=376, Percent_Identity=55.3191489361702, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1790395, Length=389, Percent_Identity=26.4781491002571, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 40729; Mature: 40597

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATLALTEQLIARASVTPDDQHCQQIMIERLAAIGFDCETLASNGVTNLWAVRRGSAGR
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCC
DGKLLAFAGHTDVVPTGPLEQWSSPPFVPAHRDGRLYGRGAADMKTSLAGFVVASEEFVA
CCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHEEEEECCCCEE
AHPDHRGSIAMLITSDEEGPATDGTVKVIEALAARGERLDYCIVGEPTSSATLGDMVKNG
ECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCC
RRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAERWDDGNEYFPPTTWQVSNL
CCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
HGGTGATNVIPGHVTLLFNFRFSTASTVDGLKARVHAILDRHGFEYALTWSVSGLPFLTP
CCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEECC
RGELSDALERAILAETGVVTELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIEL
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCEEEE
RFVDPLKNVYRRVLEQLIA
EEECHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SATLALTEQLIARASVTPDDQHCQQIMIERLAAIGFDCETLASNGVTNLWAVRRGSAGR
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCC
DGKLLAFAGHTDVVPTGPLEQWSSPPFVPAHRDGRLYGRGAADMKTSLAGFVVASEEFVA
CCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHEEEEECCCCEE
AHPDHRGSIAMLITSDEEGPATDGTVKVIEALAARGERLDYCIVGEPTSSATLGDMVKNG
ECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCC
RRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAERWDDGNEYFPPTTWQVSNL
CCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
HGGTGATNVIPGHVTLLFNFRFSTASTVDGLKARVHAILDRHGFEYALTWSVSGLPFLTP
CCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEECC
RGELSDALERAILAETGVVTELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIEL
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCEEEE
RFVDPLKNVYRRVLEQLIA
EEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA