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The map label for this gene is carA [H]

Identifier: 238026777

GI number: 238026777

Start: 1244719

End: 1245861

Strand: Direct

Name: carA [H]

Synonym: bglu_1g11350

Alternate gene names: 238026777

Gene position: 1244719-1245861 (Clockwise)

Preceding gene: 238026776

Following gene: 238026778

Centisome position: 31.86

GC content: 67.8

Gene sequence:

>1143_bases
GTGTTGCCGTCTTTTTCTCCCGCCTTGCTCGCACTTGCCGACGGCACGGTCTTTCGCGGTTATTCGATCGGTGCGACCGG
CCATACGATCGGCGAAGTCGTGTTCAATACCGCGATCACCGGCTATCAGGAAATCCTCACCGACCCGAGCTACGCGCGCC
AGATCGTGACGCTCACGTATCCGCACATCGGTAACGTCGGCGTGAACCGCGAAGACGTCGAGGCGACCAAGGTCCATGCG
GCCGGCCTCATCATCCGCGACCTGCCGGTGCTGGCCTCGAACTTCCGCATGGATCGCACGCTCGACGCCTACCTGCGCGA
CGAAGGCGTGGTCGCGATCGCCGGCATCGACACCCGCAAGCTGACCCGCGTGCTGCGCGACAAGGGCGCCCAGAACGGCT
GCATCCTGACCGGTGCCGACGACGAGGCGAAGGCGATCGAACTCGCGCGCTCGTTCCCGGGCCTGGCCGGCATGGATCTC
GCGAAGGTCGTCTCGACCGACAAGCCGTTCGCCTGGAAGCAGACCGAATGGCGCCTCGAAGGCGGCTACGGCGAGCAGAC
CGCGCCGCGCTACAAGGTCGTGGCCTACGATTTCGGCGTCAAGTACAACATCCTGCGCATGCTGGCCGAGCGCGGCTGCG
ACGTTACCGTGCTGCCCGCGCAGACGAGCGCGGCCGACGCGCTGGCGCTGAATCCGGATGGCATCTTCCTGTCGAACGGC
CCCGGCGACCCGGAGCCGTGCGACTACGCGATCGCGGCGACGCGCGAATTCATCGCGCGCGGCGTGCCGACCTTCGGCAT
CTGCCTCGGCCATCAGATCATGGGGCTCGCGGTCGGCGCGAAGACGCTGAAGATGAAGACCGGCCACCACGGCGCGAACC
ACCCGGTGAAGGACCTGGCCGACGGCCGCGTCGTGATCACCTCGCAGAACCACGGCTTCGCGGTCGACGCCGCGTCGCTG
CCGGCCAACGCGCGCGCGACCCACGTCTCGCTGTTCGACGGCACGCTGCAGGGCTTCGCGCTGACCGACAAGCCGGCGTT
CTGCTTCCAGGGCCACCCGGAAGCCTCGCCCGGTCCGCACGACATCGGCTACCTGTTCGACCGCTTCACCGCGCTGATGG
ACACGGCCAAGGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
GGGCCGGCCGGGCGAACGCCGGCGAACGCCCCTCGATGGGGCGAACCGGCCGCGACAGGTCGACAGGTCGGCAGCAAGGG
TGTCCCCCAAGGAGCCCCCC

Downstream 100 bases:

>100_bases
GGCTCACGGGAGACGGCACATCATGTTCGGCCACGCACTCGGAATCACCGACTTCTGGACCTACGTCGTCGGTGCGGTGT
TCATCGTCCTGCTGCCCGGT

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLPSFSPALLALADGTVFRGYSIGATGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTYPHIGNVGVNREDVEATKVHA
AGLIIRDLPVLASNFRMDRTLDAYLRDEGVVAIAGIDTRKLTRVLRDKGAQNGCILTGADDEAKAIELARSFPGLAGMDL
AKVVSTDKPFAWKQTEWRLEGGYGEQTAPRYKVVAYDFGVKYNILRMLAERGCDVTVLPAQTSAADALALNPDGIFLSNG
PGDPEPCDYAIAATREFIARGVPTFGICLGHQIMGLAVGAKTLKMKTGHHGANHPVKDLADGRVVITSQNHGFAVDAASL
PANARATHVSLFDGTLQGFALTDKPAFCFQGHPEASPGPHDIGYLFDRFTALMDTAKARA

Sequences:

>Translated_380_residues
MLPSFSPALLALADGTVFRGYSIGATGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTYPHIGNVGVNREDVEATKVHA
AGLIIRDLPVLASNFRMDRTLDAYLRDEGVVAIAGIDTRKLTRVLRDKGAQNGCILTGADDEAKAIELARSFPGLAGMDL
AKVVSTDKPFAWKQTEWRLEGGYGEQTAPRYKVVAYDFGVKYNILRMLAERGCDVTVLPAQTSAADALALNPDGIFLSNG
PGDPEPCDYAIAATREFIARGVPTFGICLGHQIMGLAVGAKTLKMKTGHHGANHPVKDLADGRVVITSQNHGFAVDAASL
PANARATHVSLFDGTLQGFALTDKPAFCFQGHPEASPGPHDIGYLFDRFTALMDTAKARA
>Mature_380_residues
MLPSFSPALLALADGTVFRGYSIGATGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTYPHIGNVGVNREDVEATKVHA
AGLIIRDLPVLASNFRMDRTLDAYLRDEGVVAIAGIDTRKLTRVLRDKGAQNGCILTGADDEAKAIELARSFPGLAGMDL
AKVVSTDKPFAWKQTEWRLEGGYGEQTAPRYKVVAYDFGVKYNILRMLAERGCDVTVLPAQTSAADALALNPDGIFLSNG
PGDPEPCDYAIAATREFIARGVPTFGICLGHQIMGLAVGAKTLKMKTGHHGANHPVKDLADGRVVITSQNHGFAVDAASL
PANARATHVSLFDGTLQGFALTDKPAFCFQGHPEASPGPHDIGYLFDRFTALMDTAKARA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=384, Percent_Identity=38.5416666666667, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI169790915, Length=384, Percent_Identity=36.4583333333333, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI21361331, Length=384, Percent_Identity=36.4583333333333, Blast_Score=221, Evalue=1e-57,
Organism=Escherichia coli, GI1786215, Length=377, Percent_Identity=65.2519893899204, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1789760, Length=128, Percent_Identity=30.46875, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193204318, Length=384, Percent_Identity=39.3229166666667, Blast_Score=248, Evalue=5e-66,
Organism=Saccharomyces cerevisiae, GI6324878, Length=377, Percent_Identity=38.4615384615385, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322331, Length=393, Percent_Identity=37.1501272264631, Blast_Score=234, Evalue=1e-62,
Organism=Drosophila melanogaster, GI45555749, Length=379, Percent_Identity=38.7862796833773, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24642586, Length=379, Percent_Identity=38.7862796833773, Blast_Score=231, Evalue=8e-61,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40600; Mature: 40600

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSFSPALLALADGTVFRGYSIGATGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTY
CCCCCCCCEEEEECCCEEECEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEEC
PHIGNVGVNREDVEATKVHAAGLIIRDLPVLASNFRMDRTLDAYLRDEGVVAIAGIDTRK
CCCCCCCCCCCCCHHHHHHHHCEEEHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCHHH
LTRVLRDKGAQNGCILTGADDEAKAIELARSFPGLAGMDLAKVVSTDKPFAWKQTEWRLE
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEECCCEEEEE
GGYGEQTAPRYKVVAYDFGVKYNILRMLAERGCDVTVLPAQTSAADALALNPDGIFLSNG
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCEEEECC
PGDPEPCDYAIAATREFIARGVPTFGICLGHQIMGLAVGAKTLKMKTGHHGANHPVKDLA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHC
DGRVVITSQNHGFAVDAASLPANARATHVSLFDGTLQGFALTDKPAFCFQGHPEASPGPH
CCEEEEEECCCCEEEECCCCCCCCCEEEEEEECCCCCCEEECCCCCEEECCCCCCCCCCC
DIGYLFDRFTALMDTAKARA
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLPSFSPALLALADGTVFRGYSIGATGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTY
CCCCCCCCEEEEECCCEEECEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEEC
PHIGNVGVNREDVEATKVHAAGLIIRDLPVLASNFRMDRTLDAYLRDEGVVAIAGIDTRK
CCCCCCCCCCCCCHHHHHHHHCEEEHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCHHH
LTRVLRDKGAQNGCILTGADDEAKAIELARSFPGLAGMDLAKVVSTDKPFAWKQTEWRLE
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEECCCEEEEE
GGYGEQTAPRYKVVAYDFGVKYNILRMLAERGCDVTVLPAQTSAADALALNPDGIFLSNG
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCEEEECC
PGDPEPCDYAIAATREFIARGVPTFGICLGHQIMGLAVGAKTLKMKTGHHGANHPVKDLA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHC
DGRVVITSQNHGFAVDAASLPANARATHVSLFDGTLQGFALTDKPAFCFQGHPEASPGPH
CCEEEEEECCCCEEEECCCCCCCCCEEEEEEECCCCCCEEECCCCCEEECCCCCCCCCCC
DIGYLFDRFTALMDTAKARA
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]