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The map label for this gene is mntH [H]

Identifier: 238026742

GI number: 238026742

Start: 1208889

End: 1210202

Strand: Direct

Name: mntH [H]

Synonym: bglu_1g11000

Alternate gene names: 238026742

Gene position: 1208889-1210202 (Clockwise)

Preceding gene: 238026741

Following gene: 238026743

Centisome position: 30.95

GC content: 70.09

Gene sequence:

>1314_bases
ATGCCGCTCCCGACCATACCGACCGCCCCCTTCTGCCCCGCCGAAGTGAAGGGCAGCATCACGATCGATTCGCGCGCACC
GTGGTTCGCCAAGCTGCGCCGCTTCGCCGGGCCGGGCCTGCTGATCGCGATCGGCTACATGGACCCCGGCAACTGGGCCA
CCGACATCCAGGCCGGCTCGCAGTTCGGCTATGCGTTGCTGTGGGTGGTGGCGTTCTCCAGCCTCGCCGCGATCTTCCTG
CAGATGCTGGCCGCGCGGCTCGGCCTGGTCGCCGGCCGCGATCTCGCGCAGGCCAGCTACGAGCGTTACGGCCGGTTCGG
CAAGTGGCTGCAGTGGGTGACGGCCGAGATCTCGATCATCGCCTGCGACATCGCCGAGGTGCTCGGCTGCGCGCTCGCAT
TCAAGCTGCTGCTCGGCGTGCCGGTGGCATGGGGCATCGTGCTGACCGCGCTCGACACGGTGATCGTGCTCGGGCTGCAG
GGCAAGGGCTTCCGCCAGATCGAGGCGATCGTGCTGGGCCTGATCGGCACGATGGCGTTCTGCTTCGTCGCGCAGCTCGC
GCTGCTGCCGATCGACTGGCACGCGGTGGCCGCGGGCCTGGTGCCCGGCGATCCGGGCCACGACCGCAAGGACGCGATCG
TGCTGGCGCTCGGCATCGTCGGGGCGACCATCATGCCGCACAACCTCTACCTGCATTCGTCGGTGGTGCAGACGCGCCGC
GTGGTGGGCGGCGCGGGCGGGCCGATCCGCGACACGCTGGCGATGGTGCGCGTCGACACCTGGGTGTCGCTGCTGATCGC
GATGGGCGTGAACGCGGCGATCCTGATCCTGGCCGGCGCCGCGTTCCATGCGGCCGGCCATACCGGCGTGACCGACATCG
AGCAGGCCTACCAGCTGATCACGCCGCTGGTGGGCGGCGGTGCCGCGCTGCTGTTCGGCATTGCGCTGCTGGCCTCGGGG
CAGAGCTCGACGCTGACCGGCACGATCGCCGGGCAGGTGATCATGGACGGCTTCCTGCAGGTGAAGATTCCCTGCTACCA
GCGCCGACTGATCACGCGCGCGCTGGCGCTGGTGCCGGCGCTGATCGGGGTGCTGGTGCTCGGCGACGGCGCGGTGGGCA
AGCTGCTGGTGTGGAGCCAGGTGCTGCTGAGCCTGCAACTGCCGTTCGCGATGTGGCCGCTGATCCGCTCGGTCAGCGAC
GAGCGGCTGATGCGCGGCAACGCGATCGGCCGGCCCACGCGGCTGTTCGCGTGGCTGCTGTTCGCCGTGATCGGCGGCAC
CAACCTGCTGCTGATCACCGGCGTGATCGGCTGA

Upstream 100 bases:

>100_bases
GGGTGGGATGCCGCCGCCCGCCGGTGACGCAATGCCTCGCTACCTCAGTACAATGCGCGGATTCCCGTCCACCGCCGTTC
CTCGCGCCTGCCCGCCGCCG

Downstream 100 bases:

>100_bases
GCCGACGCGCCTTGTCCGCTCGCCCGGCCCGGCTGGCCCGGCTGGCCGGCCGCGAGGCCGCCCCGAAGCCTGCCAGGCGC
TGCGGTATGCTGCGGGGCTG

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MPLPTIPTAPFCPAEVKGSITIDSRAPWFAKLRRFAGPGLLIAIGYMDPGNWATDIQAGSQFGYALLWVVAFSSLAAIFL
QMLAARLGLVAGRDLAQASYERYGRFGKWLQWVTAEISIIACDIAEVLGCALAFKLLLGVPVAWGIVLTALDTVIVLGLQ
GKGFRQIEAIVLGLIGTMAFCFVAQLALLPIDWHAVAAGLVPGDPGHDRKDAIVLALGIVGATIMPHNLYLHSSVVQTRR
VVGGAGGPIRDTLAMVRVDTWVSLLIAMGVNAAILILAGAAFHAAGHTGVTDIEQAYQLITPLVGGGAALLFGIALLASG
QSSTLTGTIAGQVIMDGFLQVKIPCYQRRLITRALALVPALIGVLVLGDGAVGKLLVWSQVLLSLQLPFAMWPLIRSVSD
ERLMRGNAIGRPTRLFAWLLFAVIGGTNLLLITGVIG

Sequences:

>Translated_437_residues
MPLPTIPTAPFCPAEVKGSITIDSRAPWFAKLRRFAGPGLLIAIGYMDPGNWATDIQAGSQFGYALLWVVAFSSLAAIFL
QMLAARLGLVAGRDLAQASYERYGRFGKWLQWVTAEISIIACDIAEVLGCALAFKLLLGVPVAWGIVLTALDTVIVLGLQ
GKGFRQIEAIVLGLIGTMAFCFVAQLALLPIDWHAVAAGLVPGDPGHDRKDAIVLALGIVGATIMPHNLYLHSSVVQTRR
VVGGAGGPIRDTLAMVRVDTWVSLLIAMGVNAAILILAGAAFHAAGHTGVTDIEQAYQLITPLVGGGAALLFGIALLASG
QSSTLTGTIAGQVIMDGFLQVKIPCYQRRLITRALALVPALIGVLVLGDGAVGKLLVWSQVLLSLQLPFAMWPLIRSVSD
ERLMRGNAIGRPTRLFAWLLFAVIGGTNLLLITGVIG
>Mature_436_residues
PLPTIPTAPFCPAEVKGSITIDSRAPWFAKLRRFAGPGLLIAIGYMDPGNWATDIQAGSQFGYALLWVVAFSSLAAIFLQ
MLAARLGLVAGRDLAQASYERYGRFGKWLQWVTAEISIIACDIAEVLGCALAFKLLLGVPVAWGIVLTALDTVIVLGLQG
KGFRQIEAIVLGLIGTMAFCFVAQLALLPIDWHAVAAGLVPGDPGHDRKDAIVLALGIVGATIMPHNLYLHSSVVQTRRV
VGGAGGPIRDTLAMVRVDTWVSLLIAMGVNAAILILAGAAFHAAGHTGVTDIEQAYQLITPLVGGGAALLFGIALLASGQ
SSTLTGTIAGQVIMDGFLQVKIPCYQRRLITRALALVPALIGVLVLGDGAVGKLLVWSQVLLSLQLPFAMWPLIRSVSDE
RLMRGNAIGRPTRLFAWLLFAVIGGTNLLLITGVIG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=458, Percent_Identity=31.8777292576419, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI295293167, Length=430, Percent_Identity=32.7906976744186, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI295293171, Length=430, Percent_Identity=32.5581395348837, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI295293169, Length=430, Percent_Identity=32.5581395348837, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI295293178, Length=430, Percent_Identity=32.7906976744186, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI295293175, Length=430, Percent_Identity=32.7906976744186, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI295293173, Length=430, Percent_Identity=32.7906976744186, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI10835169, Length=430, Percent_Identity=32.7906976744186, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1788736, Length=415, Percent_Identity=39.0361445783133, Blast_Score=268, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17569473, Length=427, Percent_Identity=32.0843091334895, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI193210616, Length=454, Percent_Identity=31.4977973568282, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71999499, Length=455, Percent_Identity=30.989010989011, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71993856, Length=232, Percent_Identity=37.0689655172414, Blast_Score=148, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6323062, Length=394, Percent_Identity=36.5482233502538, Blast_Score=236, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6321841, Length=406, Percent_Identity=37.4384236453202, Blast_Score=219, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6324450, Length=420, Percent_Identity=32.3809523809524, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24648607, Length=434, Percent_Identity=31.3364055299539, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI281362176, Length=434, Percent_Identity=31.3364055299539, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24648609, Length=434, Percent_Identity=31.3364055299539, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI45553443, Length=406, Percent_Identity=31.7733990147783, Blast_Score=205, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 46092; Mature: 45961

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPTIPTAPFCPAEVKGSITIDSRAPWFAKLRRFAGPGLLIAIGYMDPGNWATDIQAGS
CCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
QFGYALLWVVAFSSLAAIFLQMLAARLGLVAGRDLAQASYERYGRFGKWLQWVTAEISII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
ACDIAEVLGCALAFKLLLGVPVAWGIVLTALDTVIVLGLQGKGFRQIEAIVLGLIGTMAF
EECHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
CFVAQLALLPIDWHAVAAGLVPGDPGHDRKDAIVLALGIVGATIMPHNLYLHSSVVQTRR
HHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
VVGGAGGPIRDTLAMVRVDTWVSLLIAMGVNAAILILAGAAFHAAGHTGVTDIEQAYQLI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHH
TPLVGGGAALLFGIALLASGQSSTLTGTIAGQVIMDGFLQVKIPCYQRRLITRALALVPA
HHHHCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHH
LIGVLVLGDGAVGKLLVWSQVLLSLQLPFAMWPLIRSVSDERLMRGNAIGRPTRLFAWLL
HHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHH
FAVIGGTNLLLITGVIG
HHHHCCCCEEEEEECCC
>Mature Secondary Structure 
PLPTIPTAPFCPAEVKGSITIDSRAPWFAKLRRFAGPGLLIAIGYMDPGNWATDIQAGS
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
QFGYALLWVVAFSSLAAIFLQMLAARLGLVAGRDLAQASYERYGRFGKWLQWVTAEISII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
ACDIAEVLGCALAFKLLLGVPVAWGIVLTALDTVIVLGLQGKGFRQIEAIVLGLIGTMAF
EECHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
CFVAQLALLPIDWHAVAAGLVPGDPGHDRKDAIVLALGIVGATIMPHNLYLHSSVVQTRR
HHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
VVGGAGGPIRDTLAMVRVDTWVSLLIAMGVNAAILILAGAAFHAAGHTGVTDIEQAYQLI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHH
TPLVGGGAALLFGIALLASGQSSTLTGTIAGQVIMDGFLQVKIPCYQRRLITRALALVPA
HHHHCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHH
LIGVLVLGDGAVGKLLVWSQVLLSLQLPFAMWPLIRSVSDERLMRGNAIGRPTRLFAWLL
HHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHH
FAVIGGTNLLLITGVIG
HHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]