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The map label for this gene is rnc [H]

Identifier: 238026617

GI number: 238026617

Start: 1039716

End: 1040999

Strand: Direct

Name: rnc [H]

Synonym: bglu_1g09640

Alternate gene names: 238026617

Gene position: 1039716-1040999 (Clockwise)

Preceding gene: 238026616

Following gene: 238026618

Centisome position: 26.61

GC content: 70.95

Gene sequence:

>1284_bases
ATGTCTCAGTCCCAGTTGGAAAGCCGGCTGCGCTACGAATTTCGCAATGCGGAATTGCTGCGTCAGGCTTTGACCCACCG
TAGCCATAGCGCCACGCATAACGAACGGCTCGAGTTCCTTGGCGACTCCGTTCTGAATTGCGCGGTGGCGGCCCTTTTGT
TCCAGCGCTTCGGCAAGCTGGACGAAGGCGACCTGTCGCGGGTGCGGGCGAACCTCGTCAAGCAGCAGTCGCTGTACGAA
ATCGCACAGGCCCTCAATATTGCCGACGGCCTGCGGCTCGGCGAAGGGGAACTGCGCAGCGGCGGGTTCCGCCGGCCGTC
GATCCTCGCGGACGCGTTCGAAGCCATCATCGGGGCGGTGTTCCTCGATGGGGGCTTCGAAGCCGCCCAGGGGGTGATCA
AGCGCCTCTATGTCCCGATTCTCGACCACATCGATCCGCGCACGCTCGGCAAGGACGCCAAGACGCTGCTGCAGGAATAC
CTGCAGGGGCACAAGATCGCGCTGCCGACCTATACCGTGGTGGCGACGCATGGTGCGGCGCACAATCAGCAGTTCGAGGT
GGAATGCACGGTGCCGAAGCTCGACGTCAAGGTGTCTGGCTCCGGGGCGAGCCGCCGCGCGGCCGAGCAGGCCGCCGCGA
AGAAGGCGCTCGACGAGGTGATGGCGCGCCCGATGGCGGCCGCCAAGTCGAAGCGCTCGAAGAGCGCGCGTGCCTCGAAG
AGCGAGCCCGAGATCGTGCCGGGCGTGAAGGGGGTGCAGGAGGCGCTCGATCTGCGCGCGGCGCCCGAGCACAAGGAACG
CGCCATGAGCCCGGCCCAGGGTGCAGCGAAGGCGTCGGCGGCCGGCGAACGCGGTGCGCCGCCGGTGGCCGTGATTCGTG
CGGCCGCGCATGCCGACACGTTGCCGCACAAGCCCGAGCGCGGCGCCAAGCCGCCCGCCGCCGACAAGTCCGCGAGCGTC
GACAAGCCGGCCGCACCTGCCGCGCCGGCCGAGCCGGAGAAGCCGGCTTCGTCGCAGCCGCCCGGCGAGCGGCCGACGGC
ACACGCGGCCTCCGTGGCCCCCGTGGCCCCCGTGGCCGAGCCGCCGGTTGCCGCCGACAAGCCCGCCGCCGATAAATCCG
CGCCCGCCGGCCAGCCGGGCGCCGCCGACAACCCCGATGCCGCGCCGCGCGGCGCCGGCGCGCCGGACCGCACGTTGCGC
GCGCGCGACATCGCGAGCGCGGCGCCCGACCCGGACGACGAGCTCTCCGTCACGCCGTTGCGCGTGGTCGATGTCGGCCG
TTGA

Upstream 100 bases:

>100_bases
AAATCACTTCAAGAACCGGCGGTAACACCGCTTCGACACGCCTTTTCGAGCCCGGCGTCCGCCGCTAGACGGAACCGGCG
CCCGCGTTATACTCCTGCTC

Downstream 100 bases:

>100_bases
ACGCCTGATCCTATCCGCGGGCCGCGTCGTGCGGCCCGCCTCGAATCGCAGCAGCCTGATATGAACGCAACCGCCACCCC
CGCATTCCGTTGCGGCATGA

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSQSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFGKLDEGDLSRVRANLVKQQSLYE
IAQALNIADGLRLGEGELRSGGFRRPSILADAFEAIIGAVFLDGGFEAAQGVIKRLYVPILDHIDPRTLGKDAKTLLQEY
LQGHKIALPTYTVVATHGAAHNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVMARPMAAAKSKRSKSARASK
SEPEIVPGVKGVQEALDLRAAPEHKERAMSPAQGAAKASAAGERGAPPVAVIRAAAHADTLPHKPERGAKPPAADKSASV
DKPAAPAAPAEPEKPASSQPPGERPTAHAASVAPVAPVAEPPVAADKPAADKSAPAGQPGAADNPDAAPRGAGAPDRTLR
ARDIASAAPDPDDELSVTPLRVVDVGR

Sequences:

>Translated_427_residues
MSQSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFGKLDEGDLSRVRANLVKQQSLYE
IAQALNIADGLRLGEGELRSGGFRRPSILADAFEAIIGAVFLDGGFEAAQGVIKRLYVPILDHIDPRTLGKDAKTLLQEY
LQGHKIALPTYTVVATHGAAHNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVMARPMAAAKSKRSKSARASK
SEPEIVPGVKGVQEALDLRAAPEHKERAMSPAQGAAKASAAGERGAPPVAVIRAAAHADTLPHKPERGAKPPAADKSASV
DKPAAPAAPAEPEKPASSQPPGERPTAHAASVAPVAPVAEPPVAADKPAADKSAPAGQPGAADNPDAAPRGAGAPDRTLR
ARDIASAAPDPDDELSVTPLRVVDVGR
>Mature_426_residues
SQSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFGKLDEGDLSRVRANLVKQQSLYEI
AQALNIADGLRLGEGELRSGGFRRPSILADAFEAIIGAVFLDGGFEAAQGVIKRLYVPILDHIDPRTLGKDAKTLLQEYL
QGHKIALPTYTVVATHGAAHNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVMARPMAAAKSKRSKSARASKS
EPEIVPGVKGVQEALDLRAAPEHKERAMSPAQGAAKASAAGERGAPPVAVIRAAAHADTLPHKPERGAKPPAADKSASVD
KPAAPAAPAEPEKPASSQPPGERPTAHAASVAPVAPVAEPPVAADKPAADKSAPAGQPGAADNPDAAPRGAGAPDRTLRA
RDIASAAPDPDDELSVTPLRVVDVGR

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=274, Percent_Identity=25.5474452554745, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI155030234, Length=274, Percent_Identity=25.5474452554745, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788920, Length=203, Percent_Identity=52.7093596059113, Blast_Score=214, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI193202651, Length=247, Percent_Identity=29.9595141700405, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17506883, Length=197, Percent_Identity=32.48730964467, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323895, Length=218, Percent_Identity=30.2752293577982, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137682, Length=232, Percent_Identity=28.8793103448276, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 44764; Mature: 44633

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFGKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEGDLSRVRANLVKQQSLYEIAQALNIADGLRLGEGELRSGGFRRPSILADAFEAIIGAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLDGGFEAAQGVIKRLYVPILDHIDPRTLGKDAKTLLQEYLQGHKIALPTYTVVATHGAA
HHCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCCEEECCEEEEEEECCCC
HNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVMARPMAAAKSKRSKSARASK
CCCEEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEPEIVPGVKGVQEALDLRAAPEHKERAMSPAQGAAKASAAGERGAPPVAVIRAAAHADT
CCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
LPHKPERGAKPPAADKSASVDKPAAPAAPAEPEKPASSQPPGERPTAHAASVAPVAPVAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPVAADKPAADKSAPAGQPGAADNPDAAPRGAGAPDRTLRARDIASAAPDPDDELSVTPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCE
RVVDVGR
EEEECCC
>Mature Secondary Structure 
SQSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFGKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEGDLSRVRANLVKQQSLYEIAQALNIADGLRLGEGELRSGGFRRPSILADAFEAIIGAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLDGGFEAAQGVIKRLYVPILDHIDPRTLGKDAKTLLQEYLQGHKIALPTYTVVATHGAA
HHCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCCEEECCEEEEEEECCCC
HNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVMARPMAAAKSKRSKSARASK
CCCEEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEPEIVPGVKGVQEALDLRAAPEHKERAMSPAQGAAKASAAGERGAPPVAVIRAAAHADT
CCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
LPHKPERGAKPPAADKSASVDKPAAPAAPAEPEKPASSQPPGERPTAHAASVAPVAPVAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPVAADKPAADKSAPAGQPGAADNPDAAPRGAGAPDRTLRARDIASAAPDPDDELSVTPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCE
RVVDVGR
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]