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The map label for this gene is lepB [H]

Identifier: 238026616

GI number: 238026616

Start: 1038675

End: 1039571

Strand: Direct

Name: lepB [H]

Synonym: bglu_1g09630

Alternate gene names: 238026616

Gene position: 1038675-1039571 (Clockwise)

Preceding gene: 238026615

Following gene: 238026617

Centisome position: 26.59

GC content: 63.21

Gene sequence:

>897_bases
ATGAATTTCGCATTGATTCTTTTTGTGCTCGTCGTCTTGACGGGTATCGCGTGGGTGCTGGACAAGCTGGTGTTCCTGCC
GCGCCGGCGCAAGGCGGCCGACGCGGCGGTCGCCGAGTTCGACCGCCAGCAGGCCCGCGTCGGCGAGCGCTTCGCCGACG
AGAACGCGGCCGAGACGCGCGCCAAGCTGCGCGACGACAAGCTGCGCCAGCCTTGGTGGCTCGAATACACGGCCAGCTTC
TTCCCGGTGATCCTGGCGGTGTTCGTGGTGCGCTCGTTCGTGGTCGAGCCGTTCAAGATCCCGTCGGGCTCGATGGTGCC
GACGCTGCTGGTCGGCGATTTCATTCTCGTGAACAAGTTCGAATACGGCCTGCGCCTGCCGATCGGCAACCAGAAGATCA
CCAAGGGCAGCCCGCTCCAGCGCGGCGACGTGGTGGTGTTCCGCTACCCGAAGGACGAATCGGTCGACTACATCAAGCGC
GTGATCGGCCTGCCCGGCGACACCGTCCAATACCTCGACAAGAAGCTAACGATCAACGGCCAGCCGGTGCCGGAGACGCC
GCTGCCCGACTTCTTCGACGAAGAGCGCATGAACTATGCGAAACAGTATGAGGAGACCATCGACGGCACGCGCAAGAACG
CGATCCTGAACAATCCGGCCGTGCCGCCGTACGTGATGGGCGCCTACGATTTCCCGTACAAGAGCAACTGCACGTACAAC
GAGCACGGCGTGATCTGCAAGGTGCCGCCCGGCCACTACTTCATGATGGGCGACAACCGCGACAACAGCGCGGACAGCCG
CTACTGGGGCTTCGTGCCCGACCGCGACATCGTCGGTCGCGCGTTCTTCATCTGGATGAACTTCAGCGACCTCAAGCGGA
TCGGCCCGTTCCACTGA

Upstream 100 bases:

>100_bases
GGCAAAAAGCGCATGAAGCAGGTGGGTTCGGTCGAGATCCCGCAGGAAGCGTTCCTCGCGATCTTGCGTGTCGAAGACAA
ATAACAGGACTGATCCTTTT

Downstream 100 bases:

>100_bases
GCCGCGCTCGCCAGCATCGCGCCATGGCCGCGCGCGATGCTGGCAAATCACTTCAAGAACCGGCGGTAACACCGCTTCGA
CACGCCTTTTCGAGCCCGGC

Product: peptidase S26A, signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNFALILFVLVVLTGIAWVLDKLVFLPRRRKAADAAVAEFDRQQARVGERFADENAAETRAKLRDDKLRQPWWLEYTASF
FPVILAVFVVRSFVVEPFKIPSGSMVPTLLVGDFILVNKFEYGLRLPIGNQKITKGSPLQRGDVVVFRYPKDESVDYIKR
VIGLPGDTVQYLDKKLTINGQPVPETPLPDFFDEERMNYAKQYEETIDGTRKNAILNNPAVPPYVMGAYDFPYKSNCTYN
EHGVICKVPPGHYFMMGDNRDNSADSRYWGFVPDRDIVGRAFFIWMNFSDLKRIGPFH

Sequences:

>Translated_298_residues
MNFALILFVLVVLTGIAWVLDKLVFLPRRRKAADAAVAEFDRQQARVGERFADENAAETRAKLRDDKLRQPWWLEYTASF
FPVILAVFVVRSFVVEPFKIPSGSMVPTLLVGDFILVNKFEYGLRLPIGNQKITKGSPLQRGDVVVFRYPKDESVDYIKR
VIGLPGDTVQYLDKKLTINGQPVPETPLPDFFDEERMNYAKQYEETIDGTRKNAILNNPAVPPYVMGAYDFPYKSNCTYN
EHGVICKVPPGHYFMMGDNRDNSADSRYWGFVPDRDIVGRAFFIWMNFSDLKRIGPFH
>Mature_298_residues
MNFALILFVLVVLTGIAWVLDKLVFLPRRRKAADAAVAEFDRQQARVGERFADENAAETRAKLRDDKLRQPWWLEYTASF
FPVILAVFVVRSFVVEPFKIPSGSMVPTLLVGDFILVNKFEYGLRLPIGNQKITKGSPLQRGDVVVFRYPKDESVDYIKR
VIGLPGDTVQYLDKKLTINGQPVPETPLPDFFDEERMNYAKQYEETIDGTRKNAILNNPAVPPYVMGAYDFPYKSNCTYN
EHGVICKVPPGHYFMMGDNRDNSADSRYWGFVPDRDIVGRAFFIWMNFSDLKRIGPFH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=344, Percent_Identity=40.9883720930233, Blast_Score=211, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 34179; Mature: 34179

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFALILFVLVVLTGIAWVLDKLVFLPRRRKAADAAVAEFDRQQARVGERFADENAAETR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AKLRDDKLRQPWWLEYTASFFPVILAVFVVRSFVVEPFKIPSGSMVPTLLVGDFILVNKF
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEEE
EYGLRLPIGNQKITKGSPLQRGDVVVFRYPKDESVDYIKRVIGLPGDTVQYLDKKLTING
CCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCEEEECC
QPVPETPLPDFFDEERMNYAKQYEETIDGTRKNAILNNPAVPPYVMGAYDFPYKSNCTYN
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCC
EHGVICKVPPGHYFMMGDNRDNSADSRYWGFVPDRDIVGRAFFIWMNFSDLKRIGPFH
CCCEEEEECCCCEEEEECCCCCCCCCCEECCCCCCHHHCEEEEEEECHHHHHHCCCCC
>Mature Secondary Structure
MNFALILFVLVVLTGIAWVLDKLVFLPRRRKAADAAVAEFDRQQARVGERFADENAAETR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AKLRDDKLRQPWWLEYTASFFPVILAVFVVRSFVVEPFKIPSGSMVPTLLVGDFILVNKF
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEEE
EYGLRLPIGNQKITKGSPLQRGDVVVFRYPKDESVDYIKRVIGLPGDTVQYLDKKLTING
CCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCEEEECC
QPVPETPLPDFFDEERMNYAKQYEETIDGTRKNAILNNPAVPPYVMGAYDFPYKSNCTYN
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCC
EHGVICKVPPGHYFMMGDNRDNSADSRYWGFVPDRDIVGRAFFIWMNFSDLKRIGPFH
CCCEEEEECCCCEEEEECCCCCCCCCCEECCCCCCHHHCEEEEEEECHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1546969 [H]