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The map label for this gene is ltaE [H]

Identifier: 238025453

GI number: 238025453

Start: 2663307

End: 2664326

Strand: Reverse

Name: ltaE [H]

Synonym: bglu_2g21450

Alternate gene names: 238025453

Gene position: 2664326-2663307 (Counterclockwise)

Preceding gene: 238025454

Following gene: 238025447

Centisome position: 94.23

GC content: 70.39

Gene sequence:

>1020_bases
ATGATCGATCTACGTAGCGATACCGTGACTCGCCCGAGTCAGCCGATGCTGGCCGCGATGAGCGCCGCCGAAGTCGGCGA
CGACGTCTGGGGCGACGATCCGACCGTCGCGCGCCTGCAGGCTGCGGTCGCGGAACGGGCCGGCAAGGAAGCGGGCCTGT
TCTTTCCGAGCGGCACGCAGAGCAATCTTGCCGCACTGATGGCGCATTGCGCGCGCGGCGACGAGTACATCGTCGGCCAG
CAGGCGCACACCTACAAGTACGAGGGCGGCGGCGCGGCCGTGCTCGGCAGCATCCAGCCCCAGCCGATCGACAACGCCGC
CGACGGCACGCTGCCGCTCGACCGCATCGCCGCCGCGATCAAGCCGATCGACAATCACTTCGCCCGCACGCGCCTGCTCG
CGCTCGAGAACACGATCGGCGGCAAGGTGCTGCCGGCCGGCTATGTCGGCGAGGCGACCGCGCTCGCGCGCCGCCGCGGC
CTGGCGACCCATCTCGACGGCGCGCGCGTCTGCAATGCCGCGGTCGCCTCGGGCAAGCCGCTCGCCGAGCTGTGCGCGCC
GTTCGATTCGGTGTCGATCTGCTTCTCGAAGGGGCTCGCCGCGCCGGTCGGCTCGGTGCTGGTCGGCAGCCGCGCGCTGA
TCGAGGTGGCCAACCGCTGGCGCAAGGTGCTCGGCGGCGGCATGCGCCAGTCCGGCGTGCTCGCGGCGGCGTGTCTGTAT
GCCTTCGATCACCACGTCGAGCGGCTCGTCGACGATCATGCCAACGCCGAGCGGCTTGCCGCCGGCCTCGCGCGGATCGA
CGAGGTGAAGGTGCTGTCGCAGGCCACCAACATGGTGTTCGCGCAGTTCCCCGACGCCGATTGCGCGCCGCTCGAAGCCT
GGCTGAAGGCACGCGGGATACTGACGCAGATGCTGTACGCCTCGCGCTTCGTCACGCATCGCGACGTGTCGGCCGACGGG
ATCGACACCTTCGTCGAGGCCGTGCGCGCCTATTTCGCGCAGAAGGCGCGAGCGGCCTGA

Upstream 100 bases:

>100_bases
AAGGGCGCGGCGGCACGCCGGATTGCGTACACTCGGTTTTTCCCGCCACCACGACGGCCGCACCGGCCTGCCGGCCCGGC
CGACACCGAGGACGCATTTC

Downstream 100 bases:

>100_bases
ATGGCCCCACGGGATGGCTGACGGGCACCGCGCGTGCCGGTGCGCGGCGTGATCGAGCCGCGCGAGTCCGGTCCGCCGCG
AGGCCCGCTTCGGCGAGATT

Product: Threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIDLRSDTVTRPSQPMLAAMSAAEVGDDVWGDDPTVARLQAAVAERAGKEAGLFFPSGTQSNLAALMAHCARGDEYIVGQ
QAHTYKYEGGGAAVLGSIQPQPIDNAADGTLPLDRIAAAIKPIDNHFARTRLLALENTIGGKVLPAGYVGEATALARRRG
LATHLDGARVCNAAVASGKPLAELCAPFDSVSICFSKGLAAPVGSVLVGSRALIEVANRWRKVLGGGMRQSGVLAAACLY
AFDHHVERLVDDHANAERLAAGLARIDEVKVLSQATNMVFAQFPDADCAPLEAWLKARGILTQMLYASRFVTHRDVSADG
IDTFVEAVRAYFAQKARAA

Sequences:

>Translated_339_residues
MIDLRSDTVTRPSQPMLAAMSAAEVGDDVWGDDPTVARLQAAVAERAGKEAGLFFPSGTQSNLAALMAHCARGDEYIVGQ
QAHTYKYEGGGAAVLGSIQPQPIDNAADGTLPLDRIAAAIKPIDNHFARTRLLALENTIGGKVLPAGYVGEATALARRRG
LATHLDGARVCNAAVASGKPLAELCAPFDSVSICFSKGLAAPVGSVLVGSRALIEVANRWRKVLGGGMRQSGVLAAACLY
AFDHHVERLVDDHANAERLAAGLARIDEVKVLSQATNMVFAQFPDADCAPLEAWLKARGILTQMLYASRFVTHRDVSADG
IDTFVEAVRAYFAQKARAA
>Mature_339_residues
MIDLRSDTVTRPSQPMLAAMSAAEVGDDVWGDDPTVARLQAAVAERAGKEAGLFFPSGTQSNLAALMAHCARGDEYIVGQ
QAHTYKYEGGGAAVLGSIQPQPIDNAADGTLPLDRIAAAIKPIDNHFARTRLLALENTIGGKVLPAGYVGEATALARRRG
LATHLDGARVCNAAVASGKPLAELCAPFDSVSICFSKGLAAPVGSVLVGSRALIEVANRWRKVLGGGMRQSGVLAAACLY
AFDHHVERLVDDHANAERLAAGLARIDEVKVLSQATNMVFAQFPDADCAPLEAWLKARGILTQMLYASRFVTHRDVSADG
IDTFVEAVRAYFAQKARAA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=334, Percent_Identity=57.7844311377245, Blast_Score=370, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI193206522, Length=346, Percent_Identity=41.907514450867, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI193206524, Length=346, Percent_Identity=42.7745664739884, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI193206520, Length=346, Percent_Identity=41.907514450867, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6320789, Length=335, Percent_Identity=37.3134328358209, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21355439, Length=298, Percent_Identity=47.6510067114094, Blast_Score=248, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 35791; Mature: 35791

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLRSDTVTRPSQPMLAAMSAAEVGDDVWGDDPTVARLQAAVAERAGKEAGLFFPSGTQ
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCH
SNLAALMAHCARGDEYIVGQQAHTYKYEGGGAAVLGSIQPQPIDNAADGTLPLDRIAAAI
HHHHHHHHHHHCCCCEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KPIDNHFARTRLLALENTIGGKVLPAGYVGEATALARRRGLATHLDGARVCNAAVASGKP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCC
LAELCAPFDSVSICFSKGLAAPVGSVLVGSRALIEVANRWRKVLGGGMRQSGVLAAACLY
HHHHHCCCHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AFDHHVERLVDDHANAERLAAGLARIDEVKVLSQATNMVFAQFPDADCAPLEAWLKARGI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHH
LTQMLYASRFVTHRDVSADGIDTFVEAVRAYFAQKARAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDLRSDTVTRPSQPMLAAMSAAEVGDDVWGDDPTVARLQAAVAERAGKEAGLFFPSGTQ
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCH
SNLAALMAHCARGDEYIVGQQAHTYKYEGGGAAVLGSIQPQPIDNAADGTLPLDRIAAAI
HHHHHHHHHHHCCCCEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KPIDNHFARTRLLALENTIGGKVLPAGYVGEATALARRRGLATHLDGARVCNAAVASGKP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCC
LAELCAPFDSVSICFSKGLAAPVGSVLVGSRALIEVANRWRKVLGGGMRQSGVLAAACLY
HHHHHCCCHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AFDHHVERLVDDHANAERLAAGLARIDEVKVLSQATNMVFAQFPDADCAPLEAWLKARGI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHH
LTQMLYASRFVTHRDVSADGIDTFVEAVRAYFAQKARAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]