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The map label for this gene is bioI [H]

Identifier: 238025425

GI number: 238025425

Start: 2618662

End: 2619873

Strand: Reverse

Name: bioI [H]

Synonym: bglu_2g21150

Alternate gene names: 238025425

Gene position: 2619873-2618662 (Counterclockwise)

Preceding gene: 238025426

Following gene: 238025424

Centisome position: 92.66

GC content: 71.53

Gene sequence:

>1212_bases
ATGTCCGATCCCGAGATTCAGCAGGTTTCCCTCTACGATCTGTTCCAGCCGCGCTGGCGTGCCGATCCCTATCCGCTGTA
CCGCCGCCTGCGTGACGAGAGCCCGGTCCACGCGGACCCGAACGGCAACGGCTGGATCGTCTCGCGCCACGCCGACGTGG
TGGCGGTGCTCGACGACGCGCGTTTCTCGGCCGCGCGCCTGGGCGGCATCGAGGACCCGGGCGGCGCCGAGCAGCTGATC
CGCCGCACGCTGTCGAGGCAGATGCTGTTCCTCGACGGTGCCGATCACACGCGCCTGCGCAAGCTGTTCGCGAAGGCCTT
CACGCCGCGCCGGCTCGACACCTTCCGGCCGCGCATCGAGGCACTCGCGCAGCGGATGCTGGCGGCCCGGAAGGGGCACA
CGATCGACTTCATCGGCGAGTTCGCGGTGCCGTTGCCGGTGATGGTGATCGCCCTGGTGCTCGGCGTGCCGATGGACGCG
CATGCGCAACTGCACGACTGGTCGCTCGCGTTCGGCAGCGTGATCAGCGGCCGGATGCTGTCGGAGGCGGAGACGGCGCA
CGCGGAGGCCGGCATCGCCGCGTTCGGTGCGTATTTCGCGGCGCTGATCCGCGAGCGCCGGCGCGAGCCCTGCGACGACA
TGCTCAGCGATCTGCTCGCGGCCGAGGAGGCCGGCGACCGCCTGGACGAGCCGGAGCTGATCGCGAACCTGATCCTGCTG
CTGGCGGCGGGGCACGCCACCACCACCCACCTGCTCGGCAACGGCCTGCTCGCGCTGTCGCGCGAGCGCGAGCAGTGGCG
GCTGCTGGCCGACGACCCCGCCATCGCGCCGGCTGCCGTCAACGAGCTGCTGCGCTTCGACGCGCCGGTGCAGCTGACGG
GGCGCGCCGCGCGGGAAGACGTCGAACTGGGCGGACAGCGGCTGCCGAAGGGCGCCTATGTCTATACGCTGCTGGGCGCG
GCGAACCGCGACGAGCGCCATTTCGCGGCGCCGGACACGCTCGACGTGCGGCGGCCCGTGTCGCGCGTGCTCTCGTTCGG
GCACGGCGTGCATACCTGCCTCGGCGCGCTGCTCGCGCGCATCGAGGCGCAGATCGTGTTCACTTCGCTGGCCGCGCTGT
ATCCCGGCATCGAGGTGGATGCGCAACAGGCGCAGCGCACCGAGAGCCTGTCGTTCCGCGGGCTGCGCAGCCTGCCGGTA
CGGCTGGTGTGA

Upstream 100 bases:

>100_bases
AGCGAGACACCGGCACGCGGCTCGCGTAGGATCGTCGACTCCGGCGAAGCGCCGTCCCGCGATTCGCCCAGCTTCTTCGT
TCGGCACCTCCGGAGCCCCC

Downstream 100 bases:

>100_bases
GCGGCCCGTGCCGTCGGGGTTGCGCCCGCGAACACCCTCGACTGGCCTGAAGGTCGAAGCCGGCGCGCGCCTGGGGCGGG
CGGCTCGCAACGATGCTGCC

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSDPEIQQVSLYDLFQPRWRADPYPLYRRLRDESPVHADPNGNGWIVSRHADVVAVLDDARFSAARLGGIEDPGGAEQLI
RRTLSRQMLFLDGADHTRLRKLFAKAFTPRRLDTFRPRIEALAQRMLAARKGHTIDFIGEFAVPLPVMVIALVLGVPMDA
HAQLHDWSLAFGSVISGRMLSEAETAHAEAGIAAFGAYFAALIRERRREPCDDMLSDLLAAEEAGDRLDEPELIANLILL
LAAGHATTTHLLGNGLLALSREREQWRLLADDPAIAPAAVNELLRFDAPVQLTGRAAREDVELGGQRLPKGAYVYTLLGA
ANRDERHFAAPDTLDVRRPVSRVLSFGHGVHTCLGALLARIEAQIVFTSLAALYPGIEVDAQQAQRTESLSFRGLRSLPV
RLV

Sequences:

>Translated_403_residues
MSDPEIQQVSLYDLFQPRWRADPYPLYRRLRDESPVHADPNGNGWIVSRHADVVAVLDDARFSAARLGGIEDPGGAEQLI
RRTLSRQMLFLDGADHTRLRKLFAKAFTPRRLDTFRPRIEALAQRMLAARKGHTIDFIGEFAVPLPVMVIALVLGVPMDA
HAQLHDWSLAFGSVISGRMLSEAETAHAEAGIAAFGAYFAALIRERRREPCDDMLSDLLAAEEAGDRLDEPELIANLILL
LAAGHATTTHLLGNGLLALSREREQWRLLADDPAIAPAAVNELLRFDAPVQLTGRAAREDVELGGQRLPKGAYVYTLLGA
ANRDERHFAAPDTLDVRRPVSRVLSFGHGVHTCLGALLARIEAQIVFTSLAALYPGIEVDAQQAQRTESLSFRGLRSLPV
RLV
>Mature_402_residues
SDPEIQQVSLYDLFQPRWRADPYPLYRRLRDESPVHADPNGNGWIVSRHADVVAVLDDARFSAARLGGIEDPGGAEQLIR
RTLSRQMLFLDGADHTRLRKLFAKAFTPRRLDTFRPRIEALAQRMLAARKGHTIDFIGEFAVPLPVMVIALVLGVPMDAH
AQLHDWSLAFGSVISGRMLSEAETAHAEAGIAAFGAYFAALIRERRREPCDDMLSDLLAAEEAGDRLDEPELIANLILLL
AAGHATTTHLLGNGLLALSREREQWRLLADDPAIAPAAVNELLRFDAPVQLTGRAAREDVELGGQRLPKGAYVYTLLGAA
NRDERHFAAPDTLDVRRPVSRVLSFGHGVHTCLGALLARIEAQIVFTSLAALYPGIEVDAQQAQRTESLSFRGLRSLPVR
LV

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 44412; Mature: 44281

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPEIQQVSLYDLFQPRWRADPYPLYRRLRDESPVHADPNGNGWIVSRHADVVAVLDDA
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEEECCC
RFSAARLGGIEDPGGAEQLIRRTLSRQMLFLDGADHTRLRKLFAKAFTPRRLDTFRPRIE
HHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHH
ALAQRMLAARKGHTIDFIGEFAVPLPVMVIALVLGVPMDAHAQLHDWSLAFGSVISGRML
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SEAETAHAEAGIAAFGAYFAALIRERRREPCDDMLSDLLAAEEAGDRLDEPELIANLILL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LAAGHATTTHLLGNGLLALSREREQWRLLADDPAIAPAAVNELLRFDAPVQLTGRAARED
HHCCCHHHHHHHHCCHHEECCCHHHCEEECCCCCCCHHHHHHHHHCCCCCEECCHHHHHH
VELGGQRLPKGAYVYTLLGAANRDERHFAAPDTLDVRRPVSRVLSFGHGVHTCLGALLAR
HHHCHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
IEAQIVFTSLAALYPGIEVDAQQAQRTESLSFRGLRSLPVRLV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure 
SDPEIQQVSLYDLFQPRWRADPYPLYRRLRDESPVHADPNGNGWIVSRHADVVAVLDDA
CCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEEECCC
RFSAARLGGIEDPGGAEQLIRRTLSRQMLFLDGADHTRLRKLFAKAFTPRRLDTFRPRIE
HHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHH
ALAQRMLAARKGHTIDFIGEFAVPLPVMVIALVLGVPMDAHAQLHDWSLAFGSVISGRML
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SEAETAHAEAGIAAFGAYFAALIRERRREPCDDMLSDLLAAEEAGDRLDEPELIANLILL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LAAGHATTTHLLGNGLLALSREREQWRLLADDPAIAPAAVNELLRFDAPVQLTGRAARED
HHCCCHHHHHHHHCCHHEECCCHHHCEEECCCCCCCHHHHHHHHHCCCCCEECCHHHHHH
VELGGQRLPKGAYVYTLLGAANRDERHFAAPDTLDVRRPVSRVLSFGHGVHTCLGALLAR
HHHCHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
IEAQIVFTSLAALYPGIEVDAQQAQRTESLSFRGLRSLPVRLV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]