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The map label for this gene is lysN [H]

Identifier: 238025202

GI number: 238025202

Start: 2334200

End: 2335426

Strand: Reverse

Name: lysN [H]

Synonym: bglu_2g18730

Alternate gene names: 238025202

Gene position: 2335426-2334200 (Counterclockwise)

Preceding gene: 238025203

Following gene: 238025201

Centisome position: 82.6

GC content: 74.9

Gene sequence:

>1227_bases
ATGTATGACTTCACCATGCCGTTTCGCGAGCCGGCCGGCTCGCCGATTCGCGAACTGTTCAAGTACCTCGGCCAGCCGGG
GATGATCTCGCTGGCGGGCGGCTACCCGGCCGCCGGCCTGTTCGATACCGAGGGCCTGGCGGCCGCGGCCGAGCGCGCCT
GGCGCCACCCGGTGCGCTGCCTGCAATACGGGCCGACCGACGGCCTGCCCGAGCTGAAGGCCGCGCTGGCCGCGCGGATG
GCCGCGCGCGGCGCGCCCTGCAGGCCCGACGAGCTGGTGGTGACCACCGGCTCGCAGCAGGGGCTCGACCTGCTGCTGCG
CGTGCTGGTGGCGCCCGGCGACGTGGTGCTGACCGAGCAGCCGGCCTATCCGGCCACGCTCGCGGCCCTGCGGCTGCAGC
AGGCCAGCATCGTCACGCTGCCCACCGACCGCGACGGGCTCGACGTGCACGCGCTCGCCGCGCTGCTCGAATCGGGCCGC
TGCGCGCGGCCCAAGCTGCTCTACACGGTGCCGACCTTCGCCAACCCCACCGGCGCCACGCTCACGCGCGAACGGCGCCT
CGCGCTGCTCGCGCTCGCGGTGCGCCACGGCTTCGTGATCGTCGAGGACGATCCCTATGCCGAGCTGCGCTTCGCCGGCG
CGCCGCTGCCCTCGCTGCTCGCGCTCGCCGCCGAGGTGCCGGGCGCGCGCGCGCACGTCGTGCATTTCGCGAGCCTGTCG
AAGATCGTCGCGCCGGGGCTGCGGATCGGCTGGTGCGTCGCGCCCGCCGAGGTCGCGCGGCGCTGCACGGTGGCCAAGCA
GACCGTCGATCTGTGCAGTTCGCCGTGGACCCAGGCGATCGCGGCCGAGTATCTGGACGGCGGCGCGCTCGACTCTCATC
TGCCGCGCGTGGCGGCGGCCTATCGCGACAAGTGCGATGCGCTCTGCGACGCGCTCGACGCGGCGTTCGACGGTGCCATC
ACGTTTCACCGTCCCGAGGGCGGGCTGTTCGTCTGGGCGCGTGCCGCCGCGGTGGAGGCGGCGGCCTGGCTCGCGCAGGC
GCTCGAGCGCAACGTGATGTTCGTGCCGGGCGGCGCGTTCTTCGCCGATCACGCCGATCCCGCGGCGCTGCGGCTGTCGT
TCGCCGCGCCGGCGGCCGACGAGATCCGCGAGGGCGTGCGGCGGCTCAGGCTCGCGTTCGACGCGACGCTCGCGCAGGCG
GGCGGCGCCAGCGCCGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
GCTACACCTCGCTCGATCTGTCCGAACTCGACTGGCGGCGCGTGCTGGAGCGGCGCCCGATCGTCGAGAAGAACGTGGTG
TAACGGGAGCGCGGGCGATG

Downstream 100 bases:

>100_bases
GCGCGGCCGCCGCCGACACGGCTTCATGCCGGCGCGGACGGTGGCCGCCCGTCGCGTTCACGCCGTATAGCGCGAGGCGG
CTCCGCGCGTGGACGGCGCC

Product: putative GntR family transcriptional regulator

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MYDFTMPFREPAGSPIRELFKYLGQPGMISLAGGYPAAGLFDTEGLAAAAERAWRHPVRCLQYGPTDGLPELKAALAARM
AARGAPCRPDELVVTTGSQQGLDLLLRVLVAPGDVVLTEQPAYPATLAALRLQQASIVTLPTDRDGLDVHALAALLESGR
CARPKLLYTVPTFANPTGATLTRERRLALLALAVRHGFVIVEDDPYAELRFAGAPLPSLLALAAEVPGARAHVVHFASLS
KIVAPGLRIGWCVAPAEVARRCTVAKQTVDLCSSPWTQAIAAEYLDGGALDSHLPRVAAAYRDKCDALCDALDAAFDGAI
TFHRPEGGLFVWARAAAVEAAAWLAQALERNVMFVPGGAFFADHADPAALRLSFAAPAADEIREGVRRLRLAFDATLAQA
GGASAAPR

Sequences:

>Translated_408_residues
MYDFTMPFREPAGSPIRELFKYLGQPGMISLAGGYPAAGLFDTEGLAAAAERAWRHPVRCLQYGPTDGLPELKAALAARM
AARGAPCRPDELVVTTGSQQGLDLLLRVLVAPGDVVLTEQPAYPATLAALRLQQASIVTLPTDRDGLDVHALAALLESGR
CARPKLLYTVPTFANPTGATLTRERRLALLALAVRHGFVIVEDDPYAELRFAGAPLPSLLALAAEVPGARAHVVHFASLS
KIVAPGLRIGWCVAPAEVARRCTVAKQTVDLCSSPWTQAIAAEYLDGGALDSHLPRVAAAYRDKCDALCDALDAAFDGAI
TFHRPEGGLFVWARAAAVEAAAWLAQALERNVMFVPGGAFFADHADPAALRLSFAAPAADEIREGVRRLRLAFDATLAQA
GGASAAPR
>Mature_408_residues
MYDFTMPFREPAGSPIRELFKYLGQPGMISLAGGYPAAGLFDTEGLAAAAERAWRHPVRCLQYGPTDGLPELKAALAARM
AARGAPCRPDELVVTTGSQQGLDLLLRVLVAPGDVVLTEQPAYPATLAALRLQQASIVTLPTDRDGLDVHALAALLESGR
CARPKLLYTVPTFANPTGATLTRERRLALLALAVRHGFVIVEDDPYAELRFAGAPLPSLLALAAEVPGARAHVVHFASLS
KIVAPGLRIGWCVAPAEVARRCTVAKQTVDLCSSPWTQAIAAEYLDGGALDSHLPRVAAAYRDKCDALCDALDAAFDGAI
TFHRPEGGLFVWARAAAVEAAAWLAQALERNVMFVPGGAFFADHADPAALRLSFAAPAADEIREGVRRLRLAFDATLAQA
GGASAAPR

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=399, Percent_Identity=31.077694235589, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI33469970, Length=399, Percent_Identity=31.077694235589, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1790797, Length=346, Percent_Identity=29.1907514450867, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787710, Length=325, Percent_Identity=28.9230769230769, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=27.3480662983425, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=26.6483516483516, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321236, Length=487, Percent_Identity=23.8193018480493, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321929, Length=384, Percent_Identity=23.4375, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321000, Length=242, Percent_Identity=26.8595041322314, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356535, Length=394, Percent_Identity=24.6192893401015, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43155; Mature: 43155

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDFTMPFREPAGSPIRELFKYLGQPGMISLAGGYPAAGLFDTEGLAAAAERAWRHPVRC
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHH
LQYGPTDGLPELKAALAARMAARGAPCRPDELVVTTGSQQGLDLLLRVLVAPGDVVLTEQ
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECC
PAYPATLAALRLQQASIVTLPTDRDGLDVHALAALLESGRCARPKLLYTVPTFANPTGAT
CCCHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
LTRERRLALLALAVRHGFVIVEDDPYAELRFAGAPLPSLLALAAEVPGARAHVVHFASLS
HHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHH
KIVAPGLRIGWCVAPAEVARRCTVAKQTVDLCSSPWTQAIAAEYLDGGALDSHLPRVAAA
HHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHH
YRDKCDALCDALDAAFDGAITFHRPEGGLFVWARAAAVEAAAWLAQALERNVMFVPGGAF
HHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEECCCCE
FADHADPAALRLSFAAPAADEIREGVRRLRLAFDATLAQAGGASAAPR
ECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYDFTMPFREPAGSPIRELFKYLGQPGMISLAGGYPAAGLFDTEGLAAAAERAWRHPVRC
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHH
LQYGPTDGLPELKAALAARMAARGAPCRPDELVVTTGSQQGLDLLLRVLVAPGDVVLTEQ
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECC
PAYPATLAALRLQQASIVTLPTDRDGLDVHALAALLESGRCARPKLLYTVPTFANPTGAT
CCCHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
LTRERRLALLALAVRHGFVIVEDDPYAELRFAGAPLPSLLALAAEVPGARAHVVHFASLS
HHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHH
KIVAPGLRIGWCVAPAEVARRCTVAKQTVDLCSSPWTQAIAAEYLDGGALDSHLPRVAAA
HHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHH
YRDKCDALCDALDAAFDGAITFHRPEGGLFVWARAAAVEAAAWLAQALERNVMFVPGGAF
HHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEECCCCE
FADHADPAALRLSFAAPAADEIREGVRRLRLAFDATLAQAGGASAAPR
ECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA