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The map label for this gene is luxQ [H]

Identifier: 238025196

GI number: 238025196

Start: 2327111

End: 2328790

Strand: Reverse

Name: luxQ [H]

Synonym: bglu_2g18670

Alternate gene names: 238025196

Gene position: 2328790-2327111 (Counterclockwise)

Preceding gene: 238025197

Following gene: 238025193

Centisome position: 82.37

GC content: 70.77

Gene sequence:

>1680_bases
ATGCACGACCGTCTCGACGACCCGGACGAACCCGCCGCGCAGCCGGCCCCGCAATTCGCCGCCCCGCCCGGCCCCGGCGC
GGCGGCGGCGGCCTTCGACTGCCTGCCGGACGCCTACCTGATCCTCAACGCGCGCCACGAAGTGGTGCTCGCGAACCGCC
GCTACCTGAAGCTGGTCGGCGCGGTGCGCGAGGCGATCCTCGGGCGCCGCGTGCAGGACATCAACCAGTTCGGCGCCGAT
GCACAGCGCGAGGCGCGCCGCGAATGGCTCGACGCCACGCTGGAGCAACTGCCGCGGCGCGAAGCGGTGTGGTCGCCGGT
GTTTCGCTACGAGATGCCGGTCGAGCACGAGAGCGGCGAATGGGTGACGGCGCCGCGCTACTGGCGCATCAAGGCGACGC
TGCTCGATTCGTCCGAGCCGGGGCTGGCCGGCGCCGTCGCGATTCTCGTCAGCGAGGTGACCGAGCACGTCGCCGAGTAC
GAACGCGACCAGCGCGAGCGCGCCAAGCTGCGCTCGCAGGCGCAGCTGCGCCAGCTGGTGGCCGAGGAAGCGCGCGCCCA
GCTGCGCGAGCACCAGGAGCGCCTGGAGATCGCCATGGCGTTCTCGCAGGTGGGCGCCTGGGAGCTCGAACCGCTCACGG
GCGGCATCCAGTGCACCGACCAGTGCCGGACCAATCTCGGGCTGGGCATCGACGACCTGCTCACGCGCGAACGCTGGTTC
GACGAGATCGTCCATCCCGACGACCGGGCTCGGCTGCACGAGGCGATGACGCAGGCGCTCGACATCCACGAGCCGTTCGA
GGTCGATTTCCGGATCGGCTGGGAGCATGGCCCGGTGCGCTGGATCCTGGTGCGCGGCGTGGGCCGCTATCAAACCAACG
GCGCGCTGAGCTCGGTGCACGGCTTCACGCTCGACATCACCGCGCGCAAGCAGGCCGAGCTCGAGACCCAGGCCAGCGCG
GCGGCCGACAAGCTCGCCCGCGAGCAGAGCGACCGGCTCGCCACCGCGATGGATCACTTCATCACCACCGTCAGCCATGA
GCTGCGCTCGCCGCTCAACGCGATCCTGAGCTGGTGCGAACTGATGCGGCGCTCGCCCGAGCCGTCGCTGGTCACGCGCG
CGGGGGAGGTGATCAACCGCAACGGGCGCCAACTCGCGCACATGGTGGACGACCTGCTCGACAGCGGCGCGATCGTGACG
GGCAAGCTGTCGGTGATCCCGCGGCCGATCGATCTCGGCGCGCTGGCCGGGATCGTGGTCGAGGACATGCGGATGATCGC
CGAGGCCAAGGGGCTCGCGCTGGTCGCCGACCGGCTGATGCCGGCGATGGTGATCGCCGACGAGAACCGCATGAAGCAGA
TCGTCTGGAACCTGCTGTCGAACGCGGTGAAGTTCTCGCCGCAGGGCAGCCTCATCGAGGTGGCGATCACGCCACTCGGC
GAGCGCGTCGAGCTGAGCGTGCGCGATACCGGGCGCGGCATCGATCCTTCGATGCTCGAACGCGTGTTCGAGCGCTTCCA
GCAGTCGGCGGCCGACGGCGAGGGGCGCGTGGCCGGCCTCGGGCTCGGCCTCTGGCTGGCGCGCAACCTGATGGAACGGC
AGGGGGGGGAGATCGTCGCCGAAAGCGCCGGGCTCGGCCACGGCTCGACCTTCCGCCTGTGGCTGCCGGAGTACCGCTGA

Upstream 100 bases:

>100_bases
CGGCCTGCCGTGGCGCGACCGACGCGTTCGACCACCTGGTCCGGCTGGCCAGCCTGGCCGACGCCGAGCGCGGCGTGCCT
GCCTGATGCGGACTGCCCCG

Downstream 100 bases:

>100_bases
GGCCCACGGCGGGCCGGCGGGCCGGGGCCGCCCGGCAATGCGCTTCGGCAGGGGACGGGGCGGCGTCAGCCGCTCGGGAT
TGCCCCGCGCGGCGTGCCGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MHDRLDDPDEPAAQPAPQFAAPPGPGAAAAAFDCLPDAYLILNARHEVVLANRRYLKLVGAVREAILGRRVQDINQFGAD
AQREARREWLDATLEQLPRREAVWSPVFRYEMPVEHESGEWVTAPRYWRIKATLLDSSEPGLAGAVAILVSEVTEHVAEY
ERDQRERAKLRSQAQLRQLVAEEARAQLREHQERLEIAMAFSQVGAWELEPLTGGIQCTDQCRTNLGLGIDDLLTRERWF
DEIVHPDDRARLHEAMTQALDIHEPFEVDFRIGWEHGPVRWILVRGVGRYQTNGALSSVHGFTLDITARKQAELETQASA
AADKLAREQSDRLATAMDHFITTVSHELRSPLNAILSWCELMRRSPEPSLVTRAGEVINRNGRQLAHMVDDLLDSGAIVT
GKLSVIPRPIDLGALAGIVVEDMRMIAEAKGLALVADRLMPAMVIADENRMKQIVWNLLSNAVKFSPQGSLIEVAITPLG
ERVELSVRDTGRGIDPSMLERVFERFQQSAADGEGRVAGLGLGLWLARNLMERQGGEIVAESAGLGHGSTFRLWLPEYR

Sequences:

>Translated_559_residues
MHDRLDDPDEPAAQPAPQFAAPPGPGAAAAAFDCLPDAYLILNARHEVVLANRRYLKLVGAVREAILGRRVQDINQFGAD
AQREARREWLDATLEQLPRREAVWSPVFRYEMPVEHESGEWVTAPRYWRIKATLLDSSEPGLAGAVAILVSEVTEHVAEY
ERDQRERAKLRSQAQLRQLVAEEARAQLREHQERLEIAMAFSQVGAWELEPLTGGIQCTDQCRTNLGLGIDDLLTRERWF
DEIVHPDDRARLHEAMTQALDIHEPFEVDFRIGWEHGPVRWILVRGVGRYQTNGALSSVHGFTLDITARKQAELETQASA
AADKLAREQSDRLATAMDHFITTVSHELRSPLNAILSWCELMRRSPEPSLVTRAGEVINRNGRQLAHMVDDLLDSGAIVT
GKLSVIPRPIDLGALAGIVVEDMRMIAEAKGLALVADRLMPAMVIADENRMKQIVWNLLSNAVKFSPQGSLIEVAITPLG
ERVELSVRDTGRGIDPSMLERVFERFQQSAADGEGRVAGLGLGLWLARNLMERQGGEIVAESAGLGHGSTFRLWLPEYR
>Mature_559_residues
MHDRLDDPDEPAAQPAPQFAAPPGPGAAAAAFDCLPDAYLILNARHEVVLANRRYLKLVGAVREAILGRRVQDINQFGAD
AQREARREWLDATLEQLPRREAVWSPVFRYEMPVEHESGEWVTAPRYWRIKATLLDSSEPGLAGAVAILVSEVTEHVAEY
ERDQRERAKLRSQAQLRQLVAEEARAQLREHQERLEIAMAFSQVGAWELEPLTGGIQCTDQCRTNLGLGIDDLLTRERWF
DEIVHPDDRARLHEAMTQALDIHEPFEVDFRIGWEHGPVRWILVRGVGRYQTNGALSSVHGFTLDITARKQAELETQASA
AADKLAREQSDRLATAMDHFITTVSHELRSPLNAILSWCELMRRSPEPSLVTRAGEVINRNGRQLAHMVDDLLDSGAIVT
GKLSVIPRPIDLGALAGIVVEDMRMIAEAKGLALVADRLMPAMVIADENRMKQIVWNLLSNAVKFSPQGSLIEVAITPLG
ERVELSVRDTGRGIDPSMLERVFERFQQSAADGEGRVAGLGLGLWLARNLMERQGGEIVAESAGLGHGSTFRLWLPEYR

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=275, Percent_Identity=30.1818181818182, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI145693157, Length=384, Percent_Identity=25.2604166666667, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87081816, Length=236, Percent_Identity=32.6271186440678, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=31.7596566523605, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=27.2, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=28.8888888888889, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=25.974025974026, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790861, Length=267, Percent_Identity=28.0898876404494, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788393, Length=262, Percent_Identity=26.3358778625954, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=26.5060240963855, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788549, Length=278, Percent_Identity=26.6187050359712, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=28.8793103448276, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=24.4725738396624, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62315; Mature: 62315

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDRLDDPDEPAAQPAPQFAAPPGPGAAAAAFDCLPDAYLILNARHEVVLANRRYLKLVG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCEEEEECHHHHHHHH
AVREAILGRRVQDINQFGADAQREARREWLDATLEQLPRREAVWSPVFRYEMPVEHESGE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHEECCCCCCCCC
WVTAPRYWRIKATLLDSSEPGLAGAVAILVSEVTEHVAEYERDQRERAKLRSQAQLRQLV
EEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEEARAQLREHQERLEIAMAFSQVGAWELEPLTGGIQCTDQCRTNLGLGIDDLLTRERWF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEHHHHHHCCCCCHHHHHHHHHHH
DEIVHPDDRARLHEAMTQALDIHEPFEVDFRIGWEHGPVRWILVRGVGRYQTNGALSSVH
HHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHCC
GFTLDITARKQAELETQASAAADKLAREQSDRLATAMDHFITTVSHELRSPLNAILSWCE
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMRRSPEPSLVTRAGEVINRNGRQLAHMVDDLLDSGAIVTGKLSVIPRPIDLGALAGIVV
HHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEHEECCCCCCHHHHHHHHH
EDMRMIAEAKGLALVADRLMPAMVIADENRMKQIVWNLLSNAVKFSPQGSLIEVAITPLG
HHHHHHHHHCCHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCC
ERVELSVRDTGRGIDPSMLERVFERFQQSAADGEGRVAGLGLGLWLARNLMERQGGEIVA
CEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEE
ESAGLGHGSTFRLWLPEYR
ECCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MHDRLDDPDEPAAQPAPQFAAPPGPGAAAAAFDCLPDAYLILNARHEVVLANRRYLKLVG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCEEEEECHHHHHHHH
AVREAILGRRVQDINQFGADAQREARREWLDATLEQLPRREAVWSPVFRYEMPVEHESGE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHEECCCCCCCCC
WVTAPRYWRIKATLLDSSEPGLAGAVAILVSEVTEHVAEYERDQRERAKLRSQAQLRQLV
EEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEEARAQLREHQERLEIAMAFSQVGAWELEPLTGGIQCTDQCRTNLGLGIDDLLTRERWF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEHHHHHHCCCCCHHHHHHHHHHH
DEIVHPDDRARLHEAMTQALDIHEPFEVDFRIGWEHGPVRWILVRGVGRYQTNGALSSVH
HHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHCC
GFTLDITARKQAELETQASAAADKLAREQSDRLATAMDHFITTVSHELRSPLNAILSWCE
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMRRSPEPSLVTRAGEVINRNGRQLAHMVDDLLDSGAIVTGKLSVIPRPIDLGALAGIVV
HHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEHEECCCCCCHHHHHHHHH
EDMRMIAEAKGLALVADRLMPAMVIADENRMKQIVWNLLSNAVKFSPQGSLIEVAITPLG
HHHHHHHHHCCHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCC
ERVELSVRDTGRGIDPSMLERVFERFQQSAADGEGRVAGLGLGLWLARNLMERQGGEIVA
CEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEE
ESAGLGHGSTFRLWLPEYR
ECCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA