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The map label for this gene is hmgA [H]

Identifier: 238025191

GI number: 238025191

Start: 2320144

End: 2321535

Strand: Reverse

Name: hmgA [H]

Synonym: bglu_2g18620

Alternate gene names: 238025191

Gene position: 2321535-2320144 (Counterclockwise)

Preceding gene: 238025192

Following gene: 238025190

Centisome position: 82.11

GC content: 71.84

Gene sequence:

>1392_bases
ATGACGCCCGGCCCGATGCACGGCATGAAGTCCGACCTGAAGCCCGGCCTGGCATCCGCCATCGAGGCTGCCGGCCGCGC
CGGCTACCAGTGCGGCTTCGCGAACCATTTCGCCACCGAGGCGCTGCCGGGCGCGCTGCCCGAGGGGCGCAACTCGCCGC
AGCGCGCGCCCTACGGGCTCTATGCCGAGCAGCTGTCCGGCACCGCCTTCACGGCGCCGCGCGCCCATAACCGCCGCAGC
TGGCTGTACCGGATTCGCCCGGCCGCCGTGCACGGGCCGTTCGCGCCGCTTGCGCGGCCGCAGGCCCCGGCCGCGCTGGT
GGCGGACTTCGCCGATTCGGCCGAGGTGCCGCCGACGCCGCCCGACCCGTTGCGCTGGGACCCGCTGCCGATGCCGGAGG
CGCCGACCGATTTCGTCGACGGCTGGGTGACGATGGCCGGCAACGGCTCGGCGGCCGCCATGAACGGCTGCGCGATTCAT
CTGTACGCCGCCAACCGGTCGATGCAGGGGCGCTTCTTCTACGACGCCGACGGCGAACTGCTGATCGTGCCGCAGCAGGG
GCGCCTCGCGATCGCCACCGAGCTGGGCCGGCTCGAGGTCGAGCCGCAGCAGATCGCCGTGATCCCGCGCGGCGTGCGCT
TCAGCGTGACGCTGCCCGACGGCGAGGCGCGCGGCTACCTCTGCGAGAACTTCGGCCAGCCCTTGCAGCTGCCCGATCTC
GGGCCGATCGGCTCGAACGGCCTCGCGAACCCGCGCGATTTCGAAACGCCGCACGCGGCCTACGAGGATCGCGAGGGCGA
GTTCGAGCTGGTGGCGAAACTCAACGGCCGGCTCTGGCGTGCGCCGATCGGCCATTCGCCGCTCGACGTGGTGGCCTGGC
ACGGCAACTACGCGCCATACCGCTACGATCTGCGCCGCTTCAACACCATCGGCTCGATCAGCTACGACCATCCCGATCCG
TCGATCTTCCTCGTGCTGCAGGCGCCGAGCGACACGCCCGGCGTGGACACGCTCGACTTCGTGATCTTCCCGCCGCGCTG
GCTCGCGGCCGAGGCCACGTTCCGCCCGCCCTGGTTCCACCGCAACGTGGCGAGCGAGTTCATGGGGCTCGTCCACGGCG
CCTACGACGCGAAGGCGGCCGGCTTCGTGCCGGGCGGCGCGAGCCTGCACAACTGCATGGCCGGGCACGGACCGGACGCC
GGCACGTTCGAGAAGGCGTCGGCGGCCGACACCTCGGTGCCGCACAAGCTCGACGACACCATGGCCTTCATGTTCGAGAC
GCGCGCGCTGCTGCGGCCCACCCGCTTCGCGCTGGGCGGCCCGCAGCGGCAGGCCGATTACGCGCGCTGCTGGCAGGGGC
TCGCCAAACATTTCAACCCGGAGCAACGATGA

Upstream 100 bases:

>100_bases
CCCGCATGATGGTGTTCGATGACCGGCGGCGTTGCGCCGCCCGGCTGCCCAGCGCCCGGCGCCGCGCCGCGCGCCCGGGC
CGCCCGACCGGAGCCGTGGC

Downstream 100 bases:

>100_bases
CGCCCGTCACCGATCTCGACGCGACGCGCTCGCCCGCGCTGCGCAGCTGGCTGGACAGCGCCAACCACGCGGCCTGCGAT
TTCCCGATCCAGAACCTGCC

Product: homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTPGPMHGMKSDLKPGLASAIEAAGRAGYQCGFANHFATEALPGALPEGRNSPQRAPYGLYAEQLSGTAFTAPRAHNRRS
WLYRIRPAAVHGPFAPLARPQAPAALVADFADSAEVPPTPPDPLRWDPLPMPEAPTDFVDGWVTMAGNGSAAAMNGCAIH
LYAANRSMQGRFFYDADGELLIVPQQGRLAIATELGRLEVEPQQIAVIPRGVRFSVTLPDGEARGYLCENFGQPLQLPDL
GPIGSNGLANPRDFETPHAAYEDREGEFELVAKLNGRLWRAPIGHSPLDVVAWHGNYAPYRYDLRRFNTIGSISYDHPDP
SIFLVLQAPSDTPGVDTLDFVIFPPRWLAAEATFRPPWFHRNVASEFMGLVHGAYDAKAAGFVPGGASLHNCMAGHGPDA
GTFEKASAADTSVPHKLDDTMAFMFETRALLRPTRFALGGPQRQADYARCWQGLAKHFNPEQR

Sequences:

>Translated_463_residues
MTPGPMHGMKSDLKPGLASAIEAAGRAGYQCGFANHFATEALPGALPEGRNSPQRAPYGLYAEQLSGTAFTAPRAHNRRS
WLYRIRPAAVHGPFAPLARPQAPAALVADFADSAEVPPTPPDPLRWDPLPMPEAPTDFVDGWVTMAGNGSAAAMNGCAIH
LYAANRSMQGRFFYDADGELLIVPQQGRLAIATELGRLEVEPQQIAVIPRGVRFSVTLPDGEARGYLCENFGQPLQLPDL
GPIGSNGLANPRDFETPHAAYEDREGEFELVAKLNGRLWRAPIGHSPLDVVAWHGNYAPYRYDLRRFNTIGSISYDHPDP
SIFLVLQAPSDTPGVDTLDFVIFPPRWLAAEATFRPPWFHRNVASEFMGLVHGAYDAKAAGFVPGGASLHNCMAGHGPDA
GTFEKASAADTSVPHKLDDTMAFMFETRALLRPTRFALGGPQRQADYARCWQGLAKHFNPEQR
>Mature_462_residues
TPGPMHGMKSDLKPGLASAIEAAGRAGYQCGFANHFATEALPGALPEGRNSPQRAPYGLYAEQLSGTAFTAPRAHNRRSW
LYRIRPAAVHGPFAPLARPQAPAALVADFADSAEVPPTPPDPLRWDPLPMPEAPTDFVDGWVTMAGNGSAAAMNGCAIHL
YAANRSMQGRFFYDADGELLIVPQQGRLAIATELGRLEVEPQQIAVIPRGVRFSVTLPDGEARGYLCENFGQPLQLPDLG
PIGSNGLANPRDFETPHAAYEDREGEFELVAKLNGRLWRAPIGHSPLDVVAWHGNYAPYRYDLRRFNTIGSISYDHPDPS
IFLVLQAPSDTPGVDTLDFVIFPPRWLAAEATFRPPWFHRNVASEFMGLVHGAYDAKAAGFVPGGASLHNCMAGHGPDAG
TFEKASAADTSVPHKLDDTMAFMFETRALLRPTRFALGGPQRQADYARCWQGLAKHFNPEQR

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

Organism=Homo sapiens, GI115527117, Length=443, Percent_Identity=50.5643340857788, Blast_Score=441, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17507969, Length=433, Percent_Identity=52.1939953810624, Blast_Score=442, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24583650, Length=438, Percent_Identity=49.7716894977169, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR022950 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: =1.13.11.5 [H]

Molecular weight: Translated: 50311; Mature: 50180

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPGPMHGMKSDLKPGLASAIEAAGRAGYQCGFANHFATEALPGALPEGRNSPQRAPYGL
CCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCH
YAEQLSGTAFTAPRAHNRRSWLYRIRPAAVHGPFAPLARPQAPAALVADFADSAEVPPTP
HHHHHCCCEEECCCCCCCCCEEEEECCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
PDPLRWDPLPMPEAPTDFVDGWVTMAGNGSAAAMNGCAIHLYAANRSMQGRFFYDADGEL
CCCCCCCCCCCCCCCHHHHCCEEEEECCCCCEEECCCEEEEEECCCCCCCEEEECCCCCE
LIVPQQGRLAIATELGRLEVEPQQIAVIPRGVRFSVTLPDGEARGYLCENFGQPLQLPDL
EEEECCCCEEEEEECCCEEECCCEEEEEECCEEEEEECCCCCCCCHHHHHCCCCCCCCCC
GPIGSNGLANPRDFETPHAAYEDREGEFELVAKLNGRLWRAPIGHSPLDVVAWHGNYAPY
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCEEEEECCCCCCE
RYDLRRFNTIGSISYDHPDPSIFLVLQAPSDTPGVDTLDFVIFPPRWLAAEATFRPPWFH
EHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCHHEECCCCCCCCCHH
RNVASEFMGLVHGAYDAKAAGFVPGGASLHNCMAGHGPDAGTFEKASAADTSVPHKLDDT
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
MAFMFETRALLRPTRFALGGPQRQADYARCWQGLAKHFNPEQR
HHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TPGPMHGMKSDLKPGLASAIEAAGRAGYQCGFANHFATEALPGALPEGRNSPQRAPYGL
CCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCH
YAEQLSGTAFTAPRAHNRRSWLYRIRPAAVHGPFAPLARPQAPAALVADFADSAEVPPTP
HHHHHCCCEEECCCCCCCCCEEEEECCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
PDPLRWDPLPMPEAPTDFVDGWVTMAGNGSAAAMNGCAIHLYAANRSMQGRFFYDADGEL
CCCCCCCCCCCCCCCHHHHCCEEEEECCCCCEEECCCEEEEEECCCCCCCEEEECCCCCE
LIVPQQGRLAIATELGRLEVEPQQIAVIPRGVRFSVTLPDGEARGYLCENFGQPLQLPDL
EEEECCCCEEEEEECCCEEECCCEEEEEECCEEEEEECCCCCCCCHHHHHCCCCCCCCCC
GPIGSNGLANPRDFETPHAAYEDREGEFELVAKLNGRLWRAPIGHSPLDVVAWHGNYAPY
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCEEEEECCCCCCE
RYDLRRFNTIGSISYDHPDPSIFLVLQAPSDTPGVDTLDFVIFPPRWLAAEATFRPPWFH
EHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCHHEECCCCCCCCCHH
RNVASEFMGLVHGAYDAKAAGFVPGGASLHNCMAGHGPDAGTFEKASAADTSVPHKLDDT
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
MAFMFETRALLRPTRFALGGPQRQADYARCWQGLAKHFNPEQR
HHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA