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The map label for this gene is camA [H]

Identifier: 238025186

GI number: 238025186

Start: 2313427

End: 2314668

Strand: Reverse

Name: camA [H]

Synonym: bglu_2g18570

Alternate gene names: 238025186

Gene position: 2314668-2313427 (Counterclockwise)

Preceding gene: 238025188

Following gene: 238025185

Centisome position: 81.87

GC content: 73.27

Gene sequence:

>1242_bases
ATGGACGTACTGGATGTGGTGATCGTCGGGGCGGGGCATGCGGGCGCGAACTGCGCGGCCGAACTGCGCAAGTCCGGCTT
CGAGGGCAGCGTCGCGCTGCTGTCGGACGAGACCGAGCCGCCCTACGAGCGGCCGCCGCTGACGAAGGACTATCTGACGG
GTGAGCGCGGCACCGAGCAGATCCGCTTCCGCACGCCGGAGGCCTGGCTCGAACGCGCGATCGACGTGCGCCTCGCGCAT
CGCGTCGAGGCCGTCGATCCGCAGGCGCACCTGCTGCGCCTGGCCGATGGCCGCAGCTTGCGTTACGGCAAGCTGGTATG
GGCCGCGGGCGGCACGCCGCGCCGGCTCGCCTGCGAGGGCGCGATGCTCGACGGCGTCCACGTGATCCGCGCCAAGCGCG
ACATCGATGCGCTGAAGGCGGATCTCGCCGGACGTGAGCAGGTGGTGGTGGTGGGCGGCGGCTACGTGGGGCTCGAGGCG
GCCGCGGCGCTGACCAAGCTGGGCGGTGTGCGCGTGACGGTGGTCGAGGCGCAGGCGCGCCTGCTCGCACGCGTGGCCGG
CGAGGCGCTGTCGGCATTCGTCGAGGCCGAGCATCGCGGCCGCGGCGTGGAGATCGTGACGGGGGCGCAGGTCGCCGCGC
TCGCGGGCCGCGACGGGCGCGTGGCCTCGGTCGAGCTGGCCGACGGCCGCTCGATCGCCGCTGACCTCGTGATCGTCGGC
ATCGGCATCGTGCCGAACGCACAGCCGCTGCTCGACGCGGGCGCGCGGGGCAGCAACGGCGTGGACGTGGACGAGGCGTG
CCTGACCAGCTTGCCCGACGTCTACGCGATCGGCGATTGCGCGTGCCGCGCGCATCCGCTCGTGGCGGGCGGCGCACGGC
GCATCGAGAGCGTGCCGAACGCGGTCGAGCAGGCCGGCATCGTGGCCGCGGCGATCACCGGCAAGCCGGCGCCGAAGCCG
GGCGTACCGTGGTTCTGGTCGACCCAATACGACCTGCGCATCCAGATGGCCGGGATTGCCGACGGCCATGACGAGGTGGT
GGTGCGCGGCGACGTGGCCGCGCGTGCGTTCGTGGTGCTCTATCTGCGCGGCGGCCGCGTGATCGCGCTCGACGCCGTGA
ACGCGACCAAGGAGTACGTGCAGGGGCGCGCCTTGATCGCGGCCGACGTCGTGCTGACGCGCGAGCAGCTCGAGGACGTG
TCGGTGCCGCTGCAGGCGCGCATGCCGGCCGCGAGCGTCTGA

Upstream 100 bases:

>100_bases
GTTAGGCCTGCCGCCGCGGTGCACCGGATGCGCCGGCGCGCGCTGCCGCCGGGATCGCGTCCGGCCGGACCACGGACGCA
ACTGAACAAAGGAACGAAGC

Downstream 100 bases:

>100_bases
GTGCCGGCGGCGGCGTGGCGGGCGCCGGCCGCGTGCGAGGCGGCCGGTGCATGGCGCCGTCTGCCCCGGCCTCGCGGCCG
CGCCGTCGCGGGTCGCGCGG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: oxidized ferredoxin; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MDVLDVVIVGAGHAGANCAAELRKSGFEGSVALLSDETEPPYERPPLTKDYLTGERGTEQIRFRTPEAWLERAIDVRLAH
RVEAVDPQAHLLRLADGRSLRYGKLVWAAGGTPRRLACEGAMLDGVHVIRAKRDIDALKADLAGREQVVVVGGGYVGLEA
AAALTKLGGVRVTVVEAQARLLARVAGEALSAFVEAEHRGRGVEIVTGAQVAALAGRDGRVASVELADGRSIAADLVIVG
IGIVPNAQPLLDAGARGSNGVDVDEACLTSLPDVYAIGDCACRAHPLVAGGARRIESVPNAVEQAGIVAAAITGKPAPKP
GVPWFWSTQYDLRIQMAGIADGHDEVVVRGDVAARAFVVLYLRGGRVIALDAVNATKEYVQGRALIAADVVLTREQLEDV
SVPLQARMPAASV

Sequences:

>Translated_413_residues
MDVLDVVIVGAGHAGANCAAELRKSGFEGSVALLSDETEPPYERPPLTKDYLTGERGTEQIRFRTPEAWLERAIDVRLAH
RVEAVDPQAHLLRLADGRSLRYGKLVWAAGGTPRRLACEGAMLDGVHVIRAKRDIDALKADLAGREQVVVVGGGYVGLEA
AAALTKLGGVRVTVVEAQARLLARVAGEALSAFVEAEHRGRGVEIVTGAQVAALAGRDGRVASVELADGRSIAADLVIVG
IGIVPNAQPLLDAGARGSNGVDVDEACLTSLPDVYAIGDCACRAHPLVAGGARRIESVPNAVEQAGIVAAAITGKPAPKP
GVPWFWSTQYDLRIQMAGIADGHDEVVVRGDVAARAFVVLYLRGGRVIALDAVNATKEYVQGRALIAADVVLTREQLEDV
SVPLQARMPAASV
>Mature_413_residues
MDVLDVVIVGAGHAGANCAAELRKSGFEGSVALLSDETEPPYERPPLTKDYLTGERGTEQIRFRTPEAWLERAIDVRLAH
RVEAVDPQAHLLRLADGRSLRYGKLVWAAGGTPRRLACEGAMLDGVHVIRAKRDIDALKADLAGREQVVVVGGGYVGLEA
AAALTKLGGVRVTVVEAQARLLARVAGEALSAFVEAEHRGRGVEIVTGAQVAALAGRDGRVASVELADGRSIAADLVIVG
IGIVPNAQPLLDAGARGSNGVDVDEACLTSLPDVYAIGDCACRAHPLVAGGARRIESVPNAVEQAGIVAAAITGKPAPKP
GVPWFWSTQYDLRIQMAGIADGHDEVVVRGDVAARAFVVLYLRGGRVIALDAVNATKEYVQGRALIAADVVLTREQLEDV
SVPLQARMPAASV

Specific function: The oxidation of camphor by cytochrome P450-CAM requires the participation of a flavoprotein, putidaredoxin reductase, and an iron-sulfur protein, putidaredoxin, to mediate the transfer of electrons from NADH to P450 for oxygen activation [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI21389617, Length=377, Percent_Identity=31.8302387267904, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI65787454, Length=377, Percent_Identity=31.8302387267904, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI226437568, Length=377, Percent_Identity=31.8302387267904, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI4757732, Length=335, Percent_Identity=25.3731343283582, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI22202629, Length=335, Percent_Identity=25.3731343283582, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788892, Length=402, Percent_Identity=32.5870646766169, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789065, Length=276, Percent_Identity=25.7246376811594, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789765, Length=309, Percent_Identity=26.8608414239482, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559934, Length=402, Percent_Identity=28.6069651741293, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24639257, Length=407, Percent_Identity=27.5184275184275, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281359715, Length=407, Percent_Identity=27.5184275184275, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281359713, Length=407, Percent_Identity=27.5184275184275, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24639250, Length=407, Percent_Identity=27.5184275184275, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI18543267, Length=407, Percent_Identity=27.5184275184275, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24639252, Length=407, Percent_Identity=27.5184275184275, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24581020, Length=362, Percent_Identity=25.6906077348066, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI28573993, Length=362, Percent_Identity=25.6906077348066, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585130, Length=366, Percent_Identity=26.2295081967213, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: 1.18.1.3

Molecular weight: Translated: 43283; Mature: 43283

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLDVVIVGAGHAGANCAAELRKSGFEGSVALLSDETEPPYERPPLTKDYLTGERGTEQ
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCE
IRFRTPEAWLERAIDVRLAHRVEAVDPQAHLLRLADGRSLRYGKLVWAAGGTPRRLACEG
EEEECCHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCEEECEEEEECCCCCCEEEECC
AMLDGVHVIRAKRDIDALKADLAGREQVVVVGGGYVGLEAAAALTKLGGVRVTVVEAQAR
CEECCEEEEEEHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEHHHHH
LLARVAGEALSAFVEAEHRGRGVEIVTGAQVAALAGRDGRVASVELADGRSIAADLVIVG
HHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCEEEEEECCCCCCEEEEEEEE
IGIVPNAQPLLDAGARGSNGVDVDEACLTSLPDVYAIGDCACRAHPLVAGGARRIESVPN
ECCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCHHHCCCCEECCCHHHHHHHHH
AVEQAGIVAAAITGKPAPKPGVPWFWSTQYDLRIQMAGIADGHDEVVVRGDVAARAFVVL
HHHHCCEEEEEECCCCCCCCCCCEEECCCEEEEEEEEECCCCCCCEEEECCHHHEEEEEE
YLRGGRVIALDAVNATKEYVQGRALIAADVVLTREQLEDVSVPLQARMPAASV
EEECCEEEEEECCHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MDVLDVVIVGAGHAGANCAAELRKSGFEGSVALLSDETEPPYERPPLTKDYLTGERGTEQ
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCE
IRFRTPEAWLERAIDVRLAHRVEAVDPQAHLLRLADGRSLRYGKLVWAAGGTPRRLACEG
EEEECCHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCEEECEEEEECCCCCCEEEECC
AMLDGVHVIRAKRDIDALKADLAGREQVVVVGGGYVGLEAAAALTKLGGVRVTVVEAQAR
CEECCEEEEEEHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEHHHHH
LLARVAGEALSAFVEAEHRGRGVEIVTGAQVAALAGRDGRVASVELADGRSIAADLVIVG
HHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCEEEEEECCCCCCEEEEEEEE
IGIVPNAQPLLDAGARGSNGVDVDEACLTSLPDVYAIGDCACRAHPLVAGGARRIESVPN
ECCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCHHHCCCCEECCCHHHHHHHHH
AVEQAGIVAAAITGKPAPKPGVPWFWSTQYDLRIQMAGIADGHDEVVVRGDVAARAFVVL
HHHHCCEEEEEECCCCCCCCCCCEEECCCEEEEEEEEECCCCCCCEEEECCHHHEEEEEE
YLRGGRVIALDAVNATKEYVQGRALIAADVVLTREQLEDVSVPLQARMPAASV
EEECCEEEEEECCHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced ferredoxin; NAD+

Specific reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180940; 2613690; 3003058; 12011076; 11524002 [H]