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The map label for this gene is hpmB [H]

Identifier: 238025126

GI number: 238025126

Start: 2230239

End: 2231978

Strand: Reverse

Name: hpmB [H]

Synonym: bglu_2g17880

Alternate gene names: 238025126

Gene position: 2231978-2230239 (Counterclockwise)

Preceding gene: 238025127

Following gene: 238025125

Centisome position: 78.94

GC content: 63.74

Gene sequence:

>1740_bases
ATGAAAACCATTCGCCGGGGAAATTCCGCAGTGGCGGCGCTGCTATTCGTTGCGGCCAGCGTGTCGGCGCAAGAAGCGCC
GCGCCTGATCATTCCGGGCAACGACCAGCAAACCCGACAGCAGGAAGAGGCGCGTGAGCGCGAACGCACCGTCTCCGCGC
CGGGAGTACGCTCGACCGCAACGGCGAGCACCCGGTTTCCAATGCTGCCACCGGAAACGCCGTGCTTTCGCATCGATCGT
TTCTCCCTCGACGTTCCCGATGCACTGTCCGCTTCCCTGAAATCGCAAGGCGCGTCGGCATTGCTGCTCGATCGCTTCGC
CTTCGCGCGCGAATGGCTCGCGCATTACGCCGGCCAGTGCGTCGGCAAGCAAGGCATTGACGTGCTGGTCAAAGGCCTGT
CGCAGGCGATCCTGTCACGCGGGTACGTCACGACGCGCGTGCTCGTGCCCGAACAGGATCTGTCGACCGGTGCCCTCAAG
TTTTCGCTGATTCCCGGCGTAATCCGCCACGTGCGCTTCGCCGACGAGAAACTGCGCGGCACCTGGAAGACGGCCTTTTC
GACCCGCGACGGGGACCTGCTGAACCTGCGCGATCTGGAACAGGGCCTCGAGCAGATGAAGCGCGTGTCGAGCCAGGACG
TGTCGATGAAAATCGTGCCAGCTGACCTACCCGGCGAAAGCGACGTCGTGCTCGACGTCAGGCGCGGCAAGCCGTGGACC
GTCGTCGCCTCGATCGACAACTCGGGGACGCGGGCGACCGGCCGCCTGCAGGGCAGCCTGTCGCTCGGCATCGACAATCT
CTTCGGCCTGAACGACATCTTCAACATCGGCGTGAACCAGGACCTGCAGTTTGGCGACAAGCGCCTGGGCTCGCACGGCT
GGAACGGCTTTTATTCGATCCCGTGGGGCTACTGGACCGCGACGCTGTCCGCTTACACGAACACCTATTACCAGCAGATC
GCCGGCGTGAACCAGACGTTCATTGCGAGCGGCAATTCGAAGACGATCGATTTCAAGCTGAACCGCGTGCTGTCGCGCAG
CCAGAACGACGTGTTCGGTGCGCAGTTCAGGCTGTCGCGCCGGTTCGGGCAGAGCTTTATCGAAGATACGGAAATCCCGC
AGCAGCGCCGAAACAACACGTTCATCGAGTTTGGCCTGACCGATCGCCACTACTTCGGCAATGCGCAGTTCGACGGCACG
CTCGCATACCGGCAGGGTATGGGCGCATTCGGCGCGCAGGACGACAGGCTCGCCGCCGATGGCGGCCCGACCTACCGCTA
TCAGATGGCCGTGCTCGACGCCAACCTGTCGGCGCCGTTCGCGATCGCGCAGCAGCCGTTCCGGTACGTGACGACGTTCC
ACGGCCAATACACCGGCAACACGCTGTACTACATCGACGACCTGACGATTGGCAGCCGCTACACGGTGCGAGGATTCGAC
GGCGAAACGATGCTGGCGGCATCGCGCGGCTTTTATTGGCGCAACGAACTGCAGGCGTCGATCGGACAGACCGGACAGGT
GATCTATGTGGGCCTCGATTACGGCCGCGTGTGGGGTGCACAGCCGATTGCCCTGTTGGGCACGCAACTCGCGGGCGCAG
TGATCGGCGTCAAGGGCAGCGTCGCCACACACTTCGGTGCCTACGGCTACGACCTGTTCGCCGGCACGCCGGTCTACAAG
CCGTCCGGGTTTCCGACCGCGCGGGTCACGGTCGGATTCCAGGCGATGGCGCAGTTCTGA

Upstream 100 bases:

>100_bases
GATTTTCGCTTTTGTGGAATGGCCTGCACTCGATCGAAAGTGACACGCCGACCGCATGCGCGACCGAATCGTAGTCCACG
AGTACATATCTAAAAAATAC

Downstream 100 bases:

>100_bases
TGGCAAAGTCTCCCTTCGTGCCGGGTCACGCCGTCTCGGCTGAGTCGATGAAGGTTCGGCGCTGACGGCATTTCTGCGTG
CGCGGATTGAGGCGATCTTG

Product: outer membrane hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MKTIRRGNSAVAALLFVAASVSAQEAPRLIIPGNDQQTRQQEEARERERTVSAPGVRSTATASTRFPMLPPETPCFRIDR
FSLDVPDALSASLKSQGASALLLDRFAFAREWLAHYAGQCVGKQGIDVLVKGLSQAILSRGYVTTRVLVPEQDLSTGALK
FSLIPGVIRHVRFADEKLRGTWKTAFSTRDGDLLNLRDLEQGLEQMKRVSSQDVSMKIVPADLPGESDVVLDVRRGKPWT
VVASIDNSGTRATGRLQGSLSLGIDNLFGLNDIFNIGVNQDLQFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQI
AGVNQTFIASGNSKTIDFKLNRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRNNTFIEFGLTDRHYFGNAQFDGT
LAYRQGMGAFGAQDDRLAADGGPTYRYQMAVLDANLSAPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFD
GETMLAASRGFYWRNELQASIGQTGQVIYVGLDYGRVWGAQPIALLGTQLAGAVIGVKGSVATHFGAYGYDLFAGTPVYK
PSGFPTARVTVGFQAMAQF

Sequences:

>Translated_579_residues
MKTIRRGNSAVAALLFVAASVSAQEAPRLIIPGNDQQTRQQEEARERERTVSAPGVRSTATASTRFPMLPPETPCFRIDR
FSLDVPDALSASLKSQGASALLLDRFAFAREWLAHYAGQCVGKQGIDVLVKGLSQAILSRGYVTTRVLVPEQDLSTGALK
FSLIPGVIRHVRFADEKLRGTWKTAFSTRDGDLLNLRDLEQGLEQMKRVSSQDVSMKIVPADLPGESDVVLDVRRGKPWT
VVASIDNSGTRATGRLQGSLSLGIDNLFGLNDIFNIGVNQDLQFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQI
AGVNQTFIASGNSKTIDFKLNRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRNNTFIEFGLTDRHYFGNAQFDGT
LAYRQGMGAFGAQDDRLAADGGPTYRYQMAVLDANLSAPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFD
GETMLAASRGFYWRNELQASIGQTGQVIYVGLDYGRVWGAQPIALLGTQLAGAVIGVKGSVATHFGAYGYDLFAGTPVYK
PSGFPTARVTVGFQAMAQF
>Mature_579_residues
MKTIRRGNSAVAALLFVAASVSAQEAPRLIIPGNDQQTRQQEEARERERTVSAPGVRSTATASTRFPMLPPETPCFRIDR
FSLDVPDALSASLKSQGASALLLDRFAFAREWLAHYAGQCVGKQGIDVLVKGLSQAILSRGYVTTRVLVPEQDLSTGALK
FSLIPGVIRHVRFADEKLRGTWKTAFSTRDGDLLNLRDLEQGLEQMKRVSSQDVSMKIVPADLPGESDVVLDVRRGKPWT
VVASIDNSGTRATGRLQGSLSLGIDNLFGLNDIFNIGVNQDLQFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQI
AGVNQTFIASGNSKTIDFKLNRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRNNTFIEFGLTDRHYFGNAQFDGT
LAYRQGMGAFGAQDDRLAADGGPTYRYQMAVLDANLSAPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFD
GETMLAASRGFYWRNELQASIGQTGQVIYVGLDYGRVWGAQPIALLGTQLAGAVIGVKGSVATHFGAYGYDLFAGTPVYK
PSGFPTARVTVGFQAMAQF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 63681; Mature: 63681

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIRRGNSAVAALLFVAASVSAQEAPRLIIPGNDQQTRQQEEARERERTVSAPGVRSTA
CCCCCCCCHHHHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TASTRFPMLPPETPCFRIDRFSLDVPDALSASLKSQGASALLLDRFAFAREWLAHYAGQC
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VGKQGIDVLVKGLSQAILSRGYVTTRVLVPEQDLSTGALKFSLIPGVIRHVRFADEKLRG
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
TWKTAFSTRDGDLLNLRDLEQGLEQMKRVSSQDVSMKIVPADLPGESDVVLDVRRGKPWT
CHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCEE
VVASIDNSGTRATGRLQGSLSLGIDNLFGLNDIFNIGVNQDLQFGDKRLGSHGWNGFYSI
EEEEECCCCCEEEEEEEEEEEECCHHHCCCHHHHCCCCCCCCHHHHHHHCCCCCCCEEEC
PWGYWTATLSAYTNTYYQQIAGVNQTFIASGNSKTIDFKLNRVLSRSQNDVFGAQFRLSR
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHCCCCCCCCHHHHHHHH
RFGQSFIEDTEIPQQRRNNTFIEFGLTDRHYFGNAQFDGTLAYRQGMGAFGAQDDRLAAD
HHHHHHHHCCCCCHHHCCCCEEEECCCCCEEECCCCCCCEEHHHCCCCCCCCCCCCEECC
GGPTYRYQMAVLDANLSAPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFD
CCCCEEEEEEEEECCCCCCHHHHHCCCEEEEEECCEECCCEEEEEEEEEECCEEEEECCC
GETMLAASRGFYWRNELQASIGQTGQVIYVGLDYGRVWGAQPIALLGTQLAGAVIGVKGS
CCEEEEECCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCEEEECCCC
VATHFGAYGYDLFAGTPVYKPSGFPTARVTVGFQAMAQF
HHHHCCCCCEEHHCCCCCCCCCCCCEEEEEECHHHHHCC
>Mature Secondary Structure
MKTIRRGNSAVAALLFVAASVSAQEAPRLIIPGNDQQTRQQEEARERERTVSAPGVRSTA
CCCCCCCCHHHHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TASTRFPMLPPETPCFRIDRFSLDVPDALSASLKSQGASALLLDRFAFAREWLAHYAGQC
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VGKQGIDVLVKGLSQAILSRGYVTTRVLVPEQDLSTGALKFSLIPGVIRHVRFADEKLRG
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
TWKTAFSTRDGDLLNLRDLEQGLEQMKRVSSQDVSMKIVPADLPGESDVVLDVRRGKPWT
CHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCEE
VVASIDNSGTRATGRLQGSLSLGIDNLFGLNDIFNIGVNQDLQFGDKRLGSHGWNGFYSI
EEEEECCCCCEEEEEEEEEEEECCHHHCCCHHHHCCCCCCCCHHHHHHHCCCCCCCEEEC
PWGYWTATLSAYTNTYYQQIAGVNQTFIASGNSKTIDFKLNRVLSRSQNDVFGAQFRLSR
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHCCCCCCCCHHHHHHHH
RFGQSFIEDTEIPQQRRNNTFIEFGLTDRHYFGNAQFDGTLAYRQGMGAFGAQDDRLAAD
HHHHHHHHCCCCCHHHCCCCEEEECCCCCEEECCCCCCCEEHHHCCCCCCCCCCCCEECC
GGPTYRYQMAVLDANLSAPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFD
CCCCEEEEEEEEECCCCCCHHHHHCCCEEEEEECCEECCCEEEEEEEEEECCEEEEECCC
GETMLAASRGFYWRNELQASIGQTGQVIYVGLDYGRVWGAQPIALLGTQLAGAVIGVKGS
CCEEEEECCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCEEEECCCC
VATHFGAYGYDLFAGTPVYKPSGFPTARVTVGFQAMAQF
HHHHCCCCCEEHHCCCCCCCCCCCCEEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]