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The map label for this gene is frzE [H]

Identifier: 238025038

GI number: 238025038

Start: 2123937

End: 2126432

Strand: Reverse

Name: frzE [H]

Synonym: bglu_2g16950

Alternate gene names: 238025038

Gene position: 2126432-2123937 (Counterclockwise)

Preceding gene: 238025039

Following gene: 238025037

Centisome position: 75.21

GC content: 73.36

Gene sequence:

>2496_bases
ATGAGCCAAGACGACGACCTGAGCCGCCAGTCGCTGCTCGAGCTGTACCAGGAGGAGACCCAGACCCAGACCGAGGCGCT
GTCGCGGCAGTTGCTCGCGCTCGAACATGGCGCGCAGGACGCGGCCGCATTCGAGGCCTGCATGCGCGCGGCGCATTCCC
TGAAGGGCGCCGCGCGCATCGTCGGCGTGCCGCAGGGCGTGGAGATCGCCGGGCGCATGGAGGATTGCTTCGTCGGCGCG
CAGCGCGGCGAGCGCGTGCTCGGCGCGAGCCACATCGACGCGCTGCTGATGGGCGTGGACCTGCTGGTGCGGGTCGGCGA
TCCGCGCCGCGCCGCGTCGGTCACGCCGATCGAGATCGACGCGTTCGCGGTCGCGCTTGCCCATGCCGACGGTGCCGGCG
ATGCCGGGCGCGCGGCGCCGGATGCGGCCGCGCCGCTGCCGCCGGGCTTCGCCTCGGGGGCCGTCTCGGCGCTGTCGGCC
GACGCGCCGGGCAGCGCCGATTTCCCGGCGCTGGCGGATCTGTCCGCGCTGCTGCGGCTCGACGCGCCGGGCGCCGGGGC
GTCCGACACAGCCGGCGTGCCGGGCGGATCGTTGGCCGCCGGCGCCGGGCCGCGCGAGGCCGAAGCGGCGCGGCCGGCCG
ATCTGGCCGCCCAGCTGCGGCTGGCCGCCGACGCGGCGCCGGCCGCGAGGCCGCCGGCACCGCCGGCACCGCCGTCCGAG
GCGCCGGCGGCGCCCGAGCCGGGCGGCGACGCCGGCCAGATGCGCCGCGTGCGCGCCGACAGCCTGAACCGGCTGCTGAG
CCTGGCGGGCGAATCGCTGGTGGAATCGCGCTGGCTCAAGCCGTTCGCCGAATCGATGCAACGCATGCGGCGCACCCAGC
GCGACGCGGCCCGCGCGCTCGATGCCTTGTACGACGCGCTCGCCGACGATCTCGACCCGGCCCGCGAGGCCGCGATGAGC
GAGGTCCGGCAGATGCTCAACGACCTGCAGCGCACGTTCGCGGCCCGCATGGACGACCTGGACCGCTTCGAGCGGCGCAG
CATGCACATCGCCGAGCAGCTCTACGACGAGGCGCTGCAGTGCCGGATGCGCCCGTTCGGCGATGCCACGCGCGCCTATC
CGCGCATGGTCCGCGATCTGGCGCGCTCGCTCGGCAAGCGCGTGCGCTTCGCGATCGTCGGCGAGACCACCCAGGTCGAT
CGCGACCTGCTCGACCTGCTCGACGCGCCGCTCGGCCACCTGCTGCGCAACGCGCTCGACCATGGCGTCGAGCCGCCCGA
GACGCGGCTCGCGCGCGGCAAGCCGGCCGAGGCCGTCATCACGCTCGAGGCGCGCCACAGTGCCGGCTCGCTGCTCGTCA
GCGTGACCGACGACGGCCCCGGTGCCGATCTCGCGGCGGTGCGCGCCGCGATCGTGCGCCAGCGGCTCACCGACGCCGAG
ACGGCCGCGCGGCTGACCGATGCCGAGGTGCTCGAATTCCTGCTGCTGCCGGGCTTCTCGATGCGCGAGCAGGTGACCGA
CGTGTCGGGCCGCGGCGTCGGCCTCGACGCGGTCCACGAGATGGTCAAGCGCGTGCGCGGCGCGGTGCGGATCTTCAACG
AGCCGGGCCAGGGCATGCGCTTCGTGCTGCAGCTGCCGCTCACGCTGTCGGTGATCCGCAGCCTGCTGGTCGAGGTGGGC
GGCGAGCCCTATGCGTTCCCGCTGGTCCACGTGCGGCGCGCGCTGCAGCTCGAACGCGGCTCGATCGACGTGCTCGAGGG
CCAGCAGCACTTCTCGCTCGACGAGCGCCGCGTCGGGCTGGTCACCGCGCACCAGCTGTTCGACGCGGGCGAGCCCGAGG
GCGTGCGCGCGAACACGGCCGTGGTGGTGGTCGGCACCGAGCCGGAGACCTACGGCGTGGCGGTGGACCGCTTCCTCGGC
GAGCGCATGCTGGTGGTGCAGCCGCTCGATGCCCGGCTGCAGAAGATCCGCAACGTCGCGGCCGGCGCGCTGCTCGAGAA
CGGCGATCCGGTGCTGATCGTCGATGTCGAGGATCTGGTGCGCTCGATCGACAAGCTGATTCGCGGCGGCCAGCTGACCA
AGCTGCGCAGCGGCGCCGACGGCGCGCTCGCGCGGCGCCGCAAGCAGGTGCTGGTGGTGGACGATTCGCTGACGGTGCGC
GAGCTCGAACGCAAGCTGCTCGAGAAGCGCGGCTACGCGGTGACGATCGCCGTCGACGGCATGGACGGCTGGAACGCGAT
CCGCAGCGACACCTTCGACCTCGTCGTGACCGACATCGACATGCCGCGCATGGACGGCATCGAGCTCGTCACGCTGATCA
AGCGCGACCCGCTGCTGCAAGGCGTGCCGGTCATGATCGTGTCGTACAAGGACCGCGACGAGGACCGCCGGCGCGGGCTC
GACGCCGGCGCCGACTATTATCTGGCGAAGGGCAGCTTCCACGACGAGGCGCTGCTCGACGCCGTCCACGATCTGATCGG
AGAGGCGACGTCATGA

Upstream 100 bases:

>100_bases
CCGGCAGCGCGCACACGCGCGGCGTGTTCGTCTGGCGCGAGCGGATCGTCGGGCTGATCGACGAGGAGCGGCTGTTCGAA
TCGTTGTTGCGGAGCCTGCG

Downstream 100 bases:

>100_bases
ACATCGGCATCGTCAACGATTTACCGCTCGCCGTCGCCGCGCTGCGCCGCGCCATCGCGCACCGGCCCGACCATCGCGTG
CTGTGGGTGGCCGCCGACGG

Product: chemotaxis histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 831; Mature: 830

Protein sequence:

>831_residues
MSQDDDLSRQSLLELYQEETQTQTEALSRQLLALEHGAQDAAAFEACMRAAHSLKGAARIVGVPQGVEIAGRMEDCFVGA
QRGERVLGASHIDALLMGVDLLVRVGDPRRAASVTPIEIDAFAVALAHADGAGDAGRAAPDAAAPLPPGFASGAVSALSA
DAPGSADFPALADLSALLRLDAPGAGASDTAGVPGGSLAAGAGPREAEAARPADLAAQLRLAADAAPAARPPAPPAPPSE
APAAPEPGGDAGQMRRVRADSLNRLLSLAGESLVESRWLKPFAESMQRMRRTQRDAARALDALYDALADDLDPAREAAMS
EVRQMLNDLQRTFAARMDDLDRFERRSMHIAEQLYDEALQCRMRPFGDATRAYPRMVRDLARSLGKRVRFAIVGETTQVD
RDLLDLLDAPLGHLLRNALDHGVEPPETRLARGKPAEAVITLEARHSAGSLLVSVTDDGPGADLAAVRAAIVRQRLTDAE
TAARLTDAEVLEFLLLPGFSMREQVTDVSGRGVGLDAVHEMVKRVRGAVRIFNEPGQGMRFVLQLPLTLSVIRSLLVEVG
GEPYAFPLVHVRRALQLERGSIDVLEGQQHFSLDERRVGLVTAHQLFDAGEPEGVRANTAVVVVGTEPETYGVAVDRFLG
ERMLVVQPLDARLQKIRNVAAGALLENGDPVLIVDVEDLVRSIDKLIRGGQLTKLRSGADGALARRRKQVLVVDDSLTVR
ELERKLLEKRGYAVTIAVDGMDGWNAIRSDTFDLVVTDIDMPRMDGIELVTLIKRDPLLQGVPVMIVSYKDRDEDRRRGL
DAGADYYLAKGSFHDEALLDAVHDLIGEATS

Sequences:

>Translated_831_residues
MSQDDDLSRQSLLELYQEETQTQTEALSRQLLALEHGAQDAAAFEACMRAAHSLKGAARIVGVPQGVEIAGRMEDCFVGA
QRGERVLGASHIDALLMGVDLLVRVGDPRRAASVTPIEIDAFAVALAHADGAGDAGRAAPDAAAPLPPGFASGAVSALSA
DAPGSADFPALADLSALLRLDAPGAGASDTAGVPGGSLAAGAGPREAEAARPADLAAQLRLAADAAPAARPPAPPAPPSE
APAAPEPGGDAGQMRRVRADSLNRLLSLAGESLVESRWLKPFAESMQRMRRTQRDAARALDALYDALADDLDPAREAAMS
EVRQMLNDLQRTFAARMDDLDRFERRSMHIAEQLYDEALQCRMRPFGDATRAYPRMVRDLARSLGKRVRFAIVGETTQVD
RDLLDLLDAPLGHLLRNALDHGVEPPETRLARGKPAEAVITLEARHSAGSLLVSVTDDGPGADLAAVRAAIVRQRLTDAE
TAARLTDAEVLEFLLLPGFSMREQVTDVSGRGVGLDAVHEMVKRVRGAVRIFNEPGQGMRFVLQLPLTLSVIRSLLVEVG
GEPYAFPLVHVRRALQLERGSIDVLEGQQHFSLDERRVGLVTAHQLFDAGEPEGVRANTAVVVVGTEPETYGVAVDRFLG
ERMLVVQPLDARLQKIRNVAAGALLENGDPVLIVDVEDLVRSIDKLIRGGQLTKLRSGADGALARRRKQVLVVDDSLTVR
ELERKLLEKRGYAVTIAVDGMDGWNAIRSDTFDLVVTDIDMPRMDGIELVTLIKRDPLLQGVPVMIVSYKDRDEDRRRGL
DAGADYYLAKGSFHDEALLDAVHDLIGEATS
>Mature_830_residues
SQDDDLSRQSLLELYQEETQTQTEALSRQLLALEHGAQDAAAFEACMRAAHSLKGAARIVGVPQGVEIAGRMEDCFVGAQ
RGERVLGASHIDALLMGVDLLVRVGDPRRAASVTPIEIDAFAVALAHADGAGDAGRAAPDAAAPLPPGFASGAVSALSAD
APGSADFPALADLSALLRLDAPGAGASDTAGVPGGSLAAGAGPREAEAARPADLAAQLRLAADAAPAARPPAPPAPPSEA
PAAPEPGGDAGQMRRVRADSLNRLLSLAGESLVESRWLKPFAESMQRMRRTQRDAARALDALYDALADDLDPAREAAMSE
VRQMLNDLQRTFAARMDDLDRFERRSMHIAEQLYDEALQCRMRPFGDATRAYPRMVRDLARSLGKRVRFAIVGETTQVDR
DLLDLLDAPLGHLLRNALDHGVEPPETRLARGKPAEAVITLEARHSAGSLLVSVTDDGPGADLAAVRAAIVRQRLTDAET
AARLTDAEVLEFLLLPGFSMREQVTDVSGRGVGLDAVHEMVKRVRGAVRIFNEPGQGMRFVLQLPLTLSVIRSLLVEVGG
EPYAFPLVHVRRALQLERGSIDVLEGQQHFSLDERRVGLVTAHQLFDAGEPEGVRANTAVVVVGTEPETYGVAVDRFLGE
RMLVVQPLDARLQKIRNVAAGALLENGDPVLIVDVEDLVRSIDKLIRGGQLTKLRSGADGALARRRKQVLVVDDSLTVRE
LERKLLEKRGYAVTIAVDGMDGWNAIRSDTFDLVVTDIDMPRMDGIELVTLIKRDPLLQGVPVMIVSYKDRDEDRRRGLD
AGADYYLAKGSFHDEALLDAVHDLIGEATS

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=330, Percent_Identity=35.4545454545455, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=34.8623853211009, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786599, Length=103, Percent_Identity=32.0388349514563, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89218; Mature: 89086

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDDDLSRQSLLELYQEETQTQTEALSRQLLALEHGAQDAAAFEACMRAAHSLKGAARI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHE
VGVPQGVEIAGRMEDCFVGAQRGERVLGASHIDALLMGVDLLVRVGDPRRAASVTPIEID
ECCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHH
AFAVALAHADGAGDAGRAAPDAAAPLPPGFASGAVSALSADAPGSADFPALADLSALLRL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
DAPGAGASDTAGVPGGSLAAGAGPREAEAARPADLAAQLRLAADAAPAARPPAPPAPPSE
CCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
APAAPEPGGDAGQMRRVRADSLNRLLSLAGESLVESRWLKPFAESMQRMRRTQRDAARAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALYDALADDLDPAREAAMSEVRQMLNDLQRTFAARMDDLDRFERRSMHIAEQLYDEALQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CRMRPFGDATRAYPRMVRDLARSLGKRVRFAIVGETTQVDRDLLDLLDAPLGHLLRNALD
HHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHH
HGVEPPETRLARGKPAEAVITLEARHSAGSLLVSVTDDGPGADLAAVRAAIVRQRLTDAE
CCCCCCHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
TAARLTDAEVLEFLLLPGFSMREQVTDVSGRGVGLDAVHEMVKRVRGAVRIFNEPGQGMR
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
FVLQLPLTLSVIRSLLVEVGGEPYAFPLVHVRRALQLERGSIDVLEGQQHFSLDERRVGL
EEHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHCCCCHHHHHH
VTAHQLFDAGEPEGVRANTAVVVVGTEPETYGVAVDRFLGERMLVVQPLDARLQKIRNVA
HHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
AGALLENGDPVLIVDVEDLVRSIDKLIRGGQLTKLRSGADGALARRRKQVLVVDDSLTVR
HHHHEECCCCEEEEEHHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCEEEECCCCHHH
ELERKLLEKRGYAVTIAVDGMDGWNAIRSDTFDLVVTDIDMPRMDGIELVTLIKRDPLLQ
HHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCC
GVPVMIVSYKDRDEDRRRGLDAGADYYLAKGSFHDEALLDAVHDLIGEATS
CCCEEEEEECCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQDDDLSRQSLLELYQEETQTQTEALSRQLLALEHGAQDAAAFEACMRAAHSLKGAARI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHE
VGVPQGVEIAGRMEDCFVGAQRGERVLGASHIDALLMGVDLLVRVGDPRRAASVTPIEID
ECCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHH
AFAVALAHADGAGDAGRAAPDAAAPLPPGFASGAVSALSADAPGSADFPALADLSALLRL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
DAPGAGASDTAGVPGGSLAAGAGPREAEAARPADLAAQLRLAADAAPAARPPAPPAPPSE
CCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
APAAPEPGGDAGQMRRVRADSLNRLLSLAGESLVESRWLKPFAESMQRMRRTQRDAARAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALYDALADDLDPAREAAMSEVRQMLNDLQRTFAARMDDLDRFERRSMHIAEQLYDEALQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CRMRPFGDATRAYPRMVRDLARSLGKRVRFAIVGETTQVDRDLLDLLDAPLGHLLRNALD
HHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHH
HGVEPPETRLARGKPAEAVITLEARHSAGSLLVSVTDDGPGADLAAVRAAIVRQRLTDAE
CCCCCCHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
TAARLTDAEVLEFLLLPGFSMREQVTDVSGRGVGLDAVHEMVKRVRGAVRIFNEPGQGMR
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
FVLQLPLTLSVIRSLLVEVGGEPYAFPLVHVRRALQLERGSIDVLEGQQHFSLDERRVGL
EEHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHCCCCHHHHHH
VTAHQLFDAGEPEGVRANTAVVVVGTEPETYGVAVDRFLGERMLVVQPLDARLQKIRNVA
HHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
AGALLENGDPVLIVDVEDLVRSIDKLIRGGQLTKLRSGADGALARRRKQVLVVDDSLTVR
HHHHEECCCCEEEEEHHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCEEEECCCCHHH
ELERKLLEKRGYAVTIAVDGMDGWNAIRSDTFDLVVTDIDMPRMDGIELVTLIKRDPLLQ
HHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCC
GVPVMIVSYKDRDEDRRRGLDAGADYYLAKGSFHDEALLDAVHDLIGEATS
CCCEEEEEECCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]