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The map label for this gene is udg [H]

Identifier: 238024995

GI number: 238024995

Start: 2075070

End: 2076506

Strand: Reverse

Name: udg [H]

Synonym: bglu_2g16520

Alternate gene names: 238024995

Gene position: 2076506-2075070 (Counterclockwise)

Preceding gene: 238024996

Following gene: 238024994

Centisome position: 73.44

GC content: 71.89

Gene sequence:

>1437_bases
ATGAACCTGACCATCATCGGCAGCGGCTACGTGGGCCTCGTCACGGGCGCGTGCCTGGCCGACATCGGACACGACGTATT
CTGCCTCGACGTGGATCCCGTGAAGATCGGCATCCTCAACGACGGCGGCGTGCCGATTCACGAGCCGGGCCTGGCCGAAC
TGATCGCGCGCAACCGCGCGGCGGGCCGGCTGCGCTTTTCGACCGACGTCGAGGCGGCCGTGGCGCATGGGGACGTGCAG
TTCATCGCGGTGGGCACGCCGCCCGACGAGGACGGCTCGGCCGACCTGCAGTACGTGCTGGCGGCGGCGCGCAACATCGG
CCGCCACATGAGCGGCTTCAAGGTGATCGTCGACAAGTCCACGGTGCCGGTCGGCACCGCCGAGCGCGTGCGCGCGACGG
TGGCCGCCGAGCTGGCCGCACGCGGCGCCGACACCATGTTCTCGGTGGTCTCCAACCCGGAATTCCTCAAGGAAGGCGCG
GCGATCGACGATTTCGCGCGGCCCGACCGGATCGTGATCGGCTGCGACGACGACGTGCCGGGCGAGCGCGCGCGCGAGCT
GATGAAGAAGCTCTACGCGCCGTTTAACCGCAACCACGAGCGCACGCTCTACATGGACGTGCGCTCGGCCGAGTTCACCA
AGTACGCGGCCAACGCGATGCTGGCCACGCGCATCTCGTTCATGAACGAGCTGGCCAACTTCGCCGACCGCGTGGGCGCC
GACATCGAGGCGGTGCGGCGCGGCATCGGTTCCGATCCGCGCATCGGCTATCACTTCCTGTACGCCGGTGCCGGCTACGG
CGGCTCGTGCTTCCCGAAGGACGTCGAGGCGCTGATCCGCACCGCCGACGCGAGCGGCCAGTCGCTGCGGATCCTGCGCG
CGGTGTCGGACGTCAACGCCGCGCAGAAGCACGTGCTGGCCGCGAAGATCGTCGCGCGCTTCGGCGCGGACCTGAGCGGG
CGCCGCTTCGGCGTGTGGGGCCTGGCGTTCAAGCCGAACACCGACGACATGCGCGAGGCGCCCAGCCGCGCGCTGATCGG
CGAGCTGCTCGCGCGCGGCGCGCAGGTCAGCGCCTACGATCCGGTGGCCACCGCCGAGGCGCGCCGCGTGTTCGCGCTCG
ATCTGGCCGGCGCGCCCGGGCAGCTCGCGCGCCTGCGCTTCGCCGAGGATGCCGGCGACGCGGCCGACGGCGCGGATGCG
CTCGTGATCGTCACCGAATGGACCGCGTTCAAGAGCCCCGATTTCGCGGCGCTCGCCGCGCGCTGGAAGACGCCCGTGAT
CTTCGATGGGCGCAACCTGTACGAGCCGCTCGCGATGCGCGAGCTCGGCATCGAATACCACGCGATCGGCCGCGCCGGCG
CGCAGCGCGGCGCACCGGCCGCGGCGGCCGGCACCGAGGGCGGCGCCGCTCGCCCGGCCGCGCGGGTCCGCCTCTGA

Upstream 100 bases:

>100_bases
ACCGGCAGCAATGCCTACTGAGCGCGGCGCGCCGCTCCTTCTCATTTTCCGATTGACCGATCAACGAGTGGCGGCCGGCA
GCGGCCGCAAGGGCTGACAA

Downstream 100 bases:

>100_bases
GCGGCGTGCCAACCGAGAGGAGGAGGGTCCGATGTTCCAGAAGGTGCTGATCGTCTGCCACGCCAACGTGTGCCGCAGCC
CGACCGCCGAAATGCTGTTT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDPVKIGILNDGGVPIHEPGLAELIARNRAAGRLRFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMSGFKVIVDKSTVPVGTAERVRATVAAELAARGADTMFSVVSNPEFLKEGA
AIDDFARPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANFADRVGA
DIEAVRRGIGSDPRIGYHFLYAGAGYGGSCFPKDVEALIRTADASGQSLRILRAVSDVNAAQKHVLAAKIVARFGADLSG
RRFGVWGLAFKPNTDDMREAPSRALIGELLARGAQVSAYDPVATAEARRVFALDLAGAPGQLARLRFAEDAGDAADGADA
LVIVTEWTAFKSPDFAALAARWKTPVIFDGRNLYEPLAMRELGIEYHAIGRAGAQRGAPAAAAGTEGGAARPAARVRL

Sequences:

>Translated_478_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDPVKIGILNDGGVPIHEPGLAELIARNRAAGRLRFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMSGFKVIVDKSTVPVGTAERVRATVAAELAARGADTMFSVVSNPEFLKEGA
AIDDFARPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANFADRVGA
DIEAVRRGIGSDPRIGYHFLYAGAGYGGSCFPKDVEALIRTADASGQSLRILRAVSDVNAAQKHVLAAKIVARFGADLSG
RRFGVWGLAFKPNTDDMREAPSRALIGELLARGAQVSAYDPVATAEARRVFALDLAGAPGQLARLRFAEDAGDAADGADA
LVIVTEWTAFKSPDFAALAARWKTPVIFDGRNLYEPLAMRELGIEYHAIGRAGAQRGAPAAAAGTEGGAARPAARVRL
>Mature_478_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDPVKIGILNDGGVPIHEPGLAELIARNRAAGRLRFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMSGFKVIVDKSTVPVGTAERVRATVAAELAARGADTMFSVVSNPEFLKEGA
AIDDFARPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANFADRVGA
DIEAVRRGIGSDPRIGYHFLYAGAGYGGSCFPKDVEALIRTADASGQSLRILRAVSDVNAAQKHVLAAKIVARFGADLSG
RRFGVWGLAFKPNTDDMREAPSRALIGELLARGAQVSAYDPVATAEARRVFALDLAGAPGQLARLRFAEDAGDAADGADA
LVIVTEWTAFKSPDFAALAARWKTPVIFDGRNLYEPLAMRELGIEYHAIGRAGAQRGAPAAAAGTEGGAARPAARVRL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=480, Percent_Identity=35.8333333333333, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI296040438, Length=383, Percent_Identity=36.2924281984334, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI296040443, Length=338, Percent_Identity=36.6863905325444, Blast_Score=198, Evalue=1e-50,
Organism=Escherichia coli, GI1788340, Length=406, Percent_Identity=30.0492610837438, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI48994968, Length=430, Percent_Identity=28.1395348837209, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17560350, Length=470, Percent_Identity=35.3191489361702, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17136908, Length=470, Percent_Identity=34.6808510638298, Blast_Score=252, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 50764; Mature: 50764

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDPVKIGILNDGGVPIHEPGLAELIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLRFSTDVEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRHMSGFKVIVDKS
CCEEEECCCCHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTAERVRATVAAELAARGADTMFSVVSNPEFLKEGAAIDDFARPDRIVIGCDDDVP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEECCCCCC
GERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANFADRVGA
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGIGSDPRIGYHFLYAGAGYGGSCFPKDVEALIRTADASGQSLRILRAVSDVNA
CHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AQKHVLAAKIVARFGADLSGRRFGVWGLAFKPNTDDMREAPSRALIGELLARGAQVSAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCCCCCCC
PVATAEARRVFALDLAGAPGQLARLRFAEDAGDAADGADALVIVTEWTAFKSPDFAALAA
CCHHHCCCEEEEEEECCCCCHHHEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
RWKTPVIFDGRNLYEPLAMRELGIEYHAIGRAGAQRGAPAAAAGTEGGAARPAARVRL
HCCCCEEECCCCHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDPVKIGILNDGGVPIHEPGLAELIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLRFSTDVEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRHMSGFKVIVDKS
CCEEEECCCCHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTAERVRATVAAELAARGADTMFSVVSNPEFLKEGAAIDDFARPDRIVIGCDDDVP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEECCCCCC
GERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANFADRVGA
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGIGSDPRIGYHFLYAGAGYGGSCFPKDVEALIRTADASGQSLRILRAVSDVNA
CHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AQKHVLAAKIVARFGADLSGRRFGVWGLAFKPNTDDMREAPSRALIGELLARGAQVSAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCCCCCCC
PVATAEARRVFALDLAGAPGQLARLRFAEDAGDAADGADALVIVTEWTAFKSPDFAALAA
CCHHHCCCEEEEEEECCCCCHHHEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
RWKTPVIFDGRNLYEPLAMRELGIEYHAIGRAGAQRGAPAAAAGTEGGAARPAARVRL
HCCCCEEECCCCHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]