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The map label for this gene is yhdT [H]

Identifier: 238024971

GI number: 238024971

Start: 2050368

End: 2051708

Strand: Direct

Name: yhdT [H]

Synonym: bglu_2g16280

Alternate gene names: 238024971

Gene position: 2050368-2051708 (Clockwise)

Preceding gene: 238024970

Following gene: 238024973

Centisome position: 72.52

GC content: 67.41

Gene sequence:

>1341_bases
TTGATACAGATCATCGCGCTAATCGGCGCGTTGCTGCTGGTAGCCCTGAACGGATTTTTCGTGGCCGCCGAGTTCGGCCT
GGTCAAGCTGCGCGCCACGCGCGTGAAGACGCTGGCCCGCCAGCACGGCCTGCGCGGCCGCATCCTGCGCATCGTGCATG
CGCGGCTCGACGCCTACCTGTCGGCCTGCCAGCTCGGCATCACGCTCGCCTCGCTCGGCCTCGGCTGGATCGGCGAGCCG
GCCTTCGCCGACCTGCTCGCACCATTGCTCGACGCGCTCGGCATCCACTCCGCCGAACTCGTCCACGGCATCTCGCTGGT
GTTCGCGTTCTCGGTGATCTCGTTCCTGCACATCGTGGTGGGCGAACTCGCGCCGAAATCAATGGCGATCCGCCAGCCGG
AGCAGGTCGGCCTCTGGCTCGCCCTGCCGCTCTATGCGTTCTACTGGGTGATGTATCCGGCGATCTGGGTGCTCAACACG
AGCGCCAACGCGGTGCTGCGCATCGTCGGCCTGACGGCCGATCACGGCGGCGACTCGCACTACTCCACCGACGAGCTGAA
GCTGATCCTGCGCAGCCGGCGCAACGCGACGGGCGCCTCGAAGGCTCCGGTGGCGGCCTACAGCCGCGACGAATGGAACA
CGCTCGCGCATTCGCTCGACTTCACCTCGATGACGGTGTCGGACCTGATGCGCCCGGCCAACGAAATGGTCGGCCTGCGT
TGCGACCTGCCGCTCGTCGACAACATGGAAGTGGTGGCGCGCCATCGCTTCAGCCGCTACCCGCTCTTCACCGACGCCTC
GCGCGAGCAGGTGTCCGGCCTGATCCATCTGAAGGACCTGCTGCTCGCGCGCCACGCGGGCGCCGCGCTGGAGGATCTGT
CCGACTACGTGCGCCCGGTGCAGTACGTGAAGCCCGACATGCCCGCGCTCGAGCTGTTCCGGCGCTTTCGCAAGGGCGCG
CCGCATTTCGCGCTGGTGGGCAACAAGCACGAGAAGCCGATCGGCTTTCTCACGCTCGACAACCTGCTCGGCGCGCTGGT
CGGCCAGATCCACGACGAATTCCGCCAGGGCGACGCCGACTGGGCGCGCCTGGACGACGGCACGCTGATGGGCAAGGGCA
GCCTGCCCGTGGTCTCGCTGGAACAGGCGCTCGGCATCGACATCGACGAAGGCCGCGCCGAATCGGTGGGCGGCCTCGTG
ATCCAGGCGCTCGGCGATCTGCCCACCGAGGGCCAGCGCGTGTCGTTCGAGCGCTTCGACGTGGTGGTCAAGAAAATGAA
CGGGCCGCGCATCGTGCTGGTGCGCGTCTATCCGAAGGCGTTCAAGGAAGCCGACGAGTAG

Upstream 100 bases:

>100_bases
CCGCGCACGGCCTCGGTATGACGGTTTATCCGAACGGCGAAGTTTACGTTCGCCTTTCCGCCTCTATACTGACACTTCCC
TTATTACCGGAGTCGTTGCG

Downstream 100 bases:

>100_bases
GCGCGGCGGCAGCGCGGCCGCCACCCACCCTGGTCCTGGTTGGTTCGCGGCGCGGCCCGCCGCCGCTCGCTCAGGCGCCG
CGCATCATCTCGCCCGTGAT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MIQIIALIGALLLVALNGFFVAAEFGLVKLRATRVKTLARQHGLRGRILRIVHARLDAYLSACQLGITLASLGLGWIGEP
AFADLLAPLLDALGIHSAELVHGISLVFAFSVISFLHIVVGELAPKSMAIRQPEQVGLWLALPLYAFYWVMYPAIWVLNT
SANAVLRIVGLTADHGGDSHYSTDELKLILRSRRNATGASKAPVAAYSRDEWNTLAHSLDFTSMTVSDLMRPANEMVGLR
CDLPLVDNMEVVARHRFSRYPLFTDASREQVSGLIHLKDLLLARHAGAALEDLSDYVRPVQYVKPDMPALELFRRFRKGA
PHFALVGNKHEKPIGFLTLDNLLGALVGQIHDEFRQGDADWARLDDGTLMGKGSLPVVSLEQALGIDIDEGRAESVGGLV
IQALGDLPTEGQRVSFERFDVVVKKMNGPRIVLVRVYPKAFKEADE

Sequences:

>Translated_446_residues
MIQIIALIGALLLVALNGFFVAAEFGLVKLRATRVKTLARQHGLRGRILRIVHARLDAYLSACQLGITLASLGLGWIGEP
AFADLLAPLLDALGIHSAELVHGISLVFAFSVISFLHIVVGELAPKSMAIRQPEQVGLWLALPLYAFYWVMYPAIWVLNT
SANAVLRIVGLTADHGGDSHYSTDELKLILRSRRNATGASKAPVAAYSRDEWNTLAHSLDFTSMTVSDLMRPANEMVGLR
CDLPLVDNMEVVARHRFSRYPLFTDASREQVSGLIHLKDLLLARHAGAALEDLSDYVRPVQYVKPDMPALELFRRFRKGA
PHFALVGNKHEKPIGFLTLDNLLGALVGQIHDEFRQGDADWARLDDGTLMGKGSLPVVSLEQALGIDIDEGRAESVGGLV
IQALGDLPTEGQRVSFERFDVVVKKMNGPRIVLVRVYPKAFKEADE
>Mature_446_residues
MIQIIALIGALLLVALNGFFVAAEFGLVKLRATRVKTLARQHGLRGRILRIVHARLDAYLSACQLGITLASLGLGWIGEP
AFADLLAPLLDALGIHSAELVHGISLVFAFSVISFLHIVVGELAPKSMAIRQPEQVGLWLALPLYAFYWVMYPAIWVLNT
SANAVLRIVGLTADHGGDSHYSTDELKLILRSRRNATGASKAPVAAYSRDEWNTLAHSLDFTSMTVSDLMRPANEMVGLR
CDLPLVDNMEVVARHRFSRYPLFTDASREQVSGLIHLKDLLLARHAGAALEDLSDYVRPVQYVKPDMPALELFRRFRKGA
PHFALVGNKHEKPIGFLTLDNLLGALVGQIHDEFRQGDADWARLDDGTLMGKGSLPVVSLEQALGIDIDEGRAESVGGLV
IQALGDLPTEGQRVSFERFDVVVKKMNGPRIVLVRVYPKAFKEADE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=395, Percent_Identity=33.4177215189873, Blast_Score=241, Evalue=1e-63,
Organism=Escherichia coli, GI1790664, Length=441, Percent_Identity=24.0362811791383, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693175, Length=438, Percent_Identity=21.9178082191781, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082033, Length=235, Percent_Identity=22.5531914893617, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786879, Length=235, Percent_Identity=24.2553191489362, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48990; Mature: 48990

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIIALIGALLLVALNGFFVAAEFGLVKLRATRVKTLARQHGLRGRILRIVHARLDAYL
CCHHHHHHHHHHHHHHCCHHEEEHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SACQLGITLASLGLGWIGEPAFADLLAPLLDALGIHSAELVHGISLVFAFSVISFLHIVV
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GELAPKSMAIRQPEQVGLWLALPLYAFYWVMYPAIWVLNTSANAVLRIVGLTADHGGDSH
HHCCCCHHHCCCHHHHCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEEECCCCCCC
YSTDELKLILRSRRNATGASKAPVAAYSRDEWNTLAHSLDFTSMTVSDLMRPANEMVGLR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCHHHHCCCE
CDLPLVDNMEVVARHRFSRYPLFTDASREQVSGLIHLKDLLLARHAGAALEDLSDYVRPV
ECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QYVKPDMPALELFRRFRKGAPHFALVGNKHEKPIGFLTLDNLLGALVGQIHDEFRQGDAD
HHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCC
WARLDDGTLMGKGSLPVVSLEQALGIDIDEGRAESVGGLVIQALGDLPTEGQRVSFERFD
HHCCCCCEEECCCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHH
VVVKKMNGPRIVLVRVYPKAFKEADE
HHHHCCCCCEEEEEEECCHHHCCCCC
>Mature Secondary Structure
MIQIIALIGALLLVALNGFFVAAEFGLVKLRATRVKTLARQHGLRGRILRIVHARLDAYL
CCHHHHHHHHHHHHHHCCHHEEEHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SACQLGITLASLGLGWIGEPAFADLLAPLLDALGIHSAELVHGISLVFAFSVISFLHIVV
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GELAPKSMAIRQPEQVGLWLALPLYAFYWVMYPAIWVLNTSANAVLRIVGLTADHGGDSH
HHCCCCHHHCCCHHHHCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEEECCCCCCC
YSTDELKLILRSRRNATGASKAPVAAYSRDEWNTLAHSLDFTSMTVSDLMRPANEMVGLR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCHHHHCCCE
CDLPLVDNMEVVARHRFSRYPLFTDASREQVSGLIHLKDLLLARHAGAALEDLSDYVRPV
ECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QYVKPDMPALELFRRFRKGAPHFALVGNKHEKPIGFLTLDNLLGALVGQIHDEFRQGDAD
HHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCC
WARLDDGTLMGKGSLPVVSLEQALGIDIDEGRAESVGGLVIQALGDLPTEGQRVSFERFD
HHCCCCCEEECCCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHH
VVVKKMNGPRIVLVRVYPKAFKEADE
HHHHCCCCCEEEEEEECCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]