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The map label for this gene is fppS [H]

Identifier: 238024940

GI number: 238024940

Start: 2015630

End: 2016514

Strand: Reverse

Name: fppS [H]

Synonym: bglu_2g15950

Alternate gene names: 238024940

Gene position: 2016514-2015630 (Counterclockwise)

Preceding gene: 238024941

Following gene: 238024939

Centisome position: 71.32

GC content: 69.83

Gene sequence:

>885_bases
ATGACATTCCAACAATGGATGCGCGCGGTGCTGGCGCGCGTCGAAGATGCGCTTGGCCACTATCTGCCGGCCGACACGGT
GGTTCCCGGCACGCTGCACGAAGCGATGCGCTATGCGGTGATGGGTGGGGGCAAACGCGTGAGGCCGCTGCTGTGCCATG
CGGCCGGTGAGCTGACGGGCGCGAGCGAGGCGGCCAGCAATGCCGCGTCGGCCGCGCTGGAGATGATCCACGTCTATTCG
CTTGTTCACGACGACATGCCGTGCATGGACGACGATGCGCTGCGCCGTGGCAAGCCGACCGTCCACGTGCAGTATGACGA
GCCGACGGCGCTGCTGGTCGGCGACGCGCTGCAGTCGCAGGCGTTCGTGGCGCTGACCGACGCGGCCGCGCTCTCGCCGC
AGCAGCAGGCCGCGCTCGTGCGCGAGCTGGCGCTCGCGAGCGGCTCGATCGGCATGGCCGGCGGGCAGGCGATCGACCTC
GCCAGCGTCGGCCAGATGCTGACGCGCGAGCAGCTTGAGACGATGCACCGGATGAAGACGGGGGCGCTGCTGCGTGCCTC
GGTGCGCATGGGGGCGCTGGCCGGCGAGACGCCGACCGCGGACACCATGCGCGCGCTCGACGCCTATGCAGCCGCGGTCG
GTCTCGCGTTCCAGGTGGTCGACGACATTCTCGACGTCACCACCGATTCGGCCACGCTCGGCAAGACGGCTGGCAAGGAC
GCGGCAGCCAACAAGCCCACTTACGTGTCGATCATCGGTCTCGATGCGTCGCGCGAGCTGGCCGCGCAGTTGCGCGCCGA
TGCGCACGCGGCGCTGCAACCGTTCGGCGCGCGCGCGCAACGCCTTGCCGAACTCGCCGACCTGGTGGTGAACCGGGTCA
GCTGA

Upstream 100 bases:

>100_bases
AGCTCGACAAGGTGGAGCAGCAGGTGCGCGTGCTCGACGGGGCCGCGCTGAAGCCGCACTCCACCGGCGTGGCCGCTACG
GACGGCGAAGACGACGATCT

Downstream 100 bases:

>100_bases
CGCGAAAGCCCGCCGCCGCGCCTGGCCTTGCAAGAAGGCGCGCGAAGGAGTGCGGGCGCGTTTGATTTCCTACAATGGAA
CGACGATGTACGACCTGCTG

Product: polyprenyl synthetase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTFQQWMRAVLARVEDALGHYLPADTVVPGTLHEAMRYAVMGGGKRVRPLLCHAAGELTGASEAASNAASAALEMIHVYS
LVHDDMPCMDDDALRRGKPTVHVQYDEPTALLVGDALQSQAFVALTDAAALSPQQQAALVRELALASGSIGMAGGQAIDL
ASVGQMLTREQLETMHRMKTGALLRASVRMGALAGETPTADTMRALDAYAAAVGLAFQVVDDILDVTTDSATLGKTAGKD
AAANKPTYVSIIGLDASRELAAQLRADAHAALQPFGARAQRLAELADLVVNRVS

Sequences:

>Translated_294_residues
MTFQQWMRAVLARVEDALGHYLPADTVVPGTLHEAMRYAVMGGGKRVRPLLCHAAGELTGASEAASNAASAALEMIHVYS
LVHDDMPCMDDDALRRGKPTVHVQYDEPTALLVGDALQSQAFVALTDAAALSPQQQAALVRELALASGSIGMAGGQAIDL
ASVGQMLTREQLETMHRMKTGALLRASVRMGALAGETPTADTMRALDAYAAAVGLAFQVVDDILDVTTDSATLGKTAGKD
AAANKPTYVSIIGLDASRELAAQLRADAHAALQPFGARAQRLAELADLVVNRVS
>Mature_293_residues
TFQQWMRAVLARVEDALGHYLPADTVVPGTLHEAMRYAVMGGGKRVRPLLCHAAGELTGASEAASNAASAALEMIHVYSL
VHDDMPCMDDDALRRGKPTVHVQYDEPTALLVGDALQSQAFVALTDAAALSPQQQAALVRELALASGSIGMAGGQAIDLA
SVGQMLTREQLETMHRMKTGALLRASVRMGALAGETPTADTMRALDAYAAAVGLAFQVVDDILDVTTDSATLGKTAGKDA
AANKPTYVSIIGLDASRELAAQLRADAHAALQPFGARAQRLAELADLVVNRVS

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=223, Percent_Identity=31.390134529148, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI1786623, Length=297, Percent_Identity=43.7710437710438, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1789578, Length=213, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 30829; Mature: 30697

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFQQWMRAVLARVEDALGHYLPADTVVPGTLHEAMRYAVMGGGKRVRPLLCHAAGELTG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
ASEAASNAASAALEMIHVYSLVHDDMPCMDDDALRRGKPTVHVQYDEPTALLVGDALQSQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCEEEECHHHHCC
AFVALTDAAALSPQQQAALVRELALASGSIGMAGGQAIDLASVGQMLTREQLETMHRMKT
EEEEEECHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
GALLRASVRMGALAGETPTADTMRALDAYAAAVGLAFQVVDDILDVTTDSATLGKTAGKD
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
AAANKPTYVSIIGLDASRELAAQLRADAHAALQPFGARAQRLAELADLVVNRVS
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFQQWMRAVLARVEDALGHYLPADTVVPGTLHEAMRYAVMGGGKRVRPLLCHAAGELTG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
ASEAASNAASAALEMIHVYSLVHDDMPCMDDDALRRGKPTVHVQYDEPTALLVGDALQSQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCEEEECHHHHCC
AFVALTDAAALSPQQQAALVRELALASGSIGMAGGQAIDLASVGQMLTREQLETMHRMKT
EEEEEECHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
GALLRASVRMGALAGETPTADTMRALDAYAAAVGLAFQVVDDILDVTTDSATLGKTAGKD
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
AAANKPTYVSIIGLDASRELAAQLRADAHAALQPFGARAQRLAELADLVVNRVS
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9655913; 12597275 [H]