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The map label for this gene is dxs [H]

Identifier: 238024939

GI number: 238024939

Start: 2013640

End: 2015544

Strand: Reverse

Name: dxs [H]

Synonym: bglu_2g15940

Alternate gene names: 238024939

Gene position: 2015544-2013640 (Counterclockwise)

Preceding gene: 238024940

Following gene: 238024938

Centisome position: 71.29

GC content: 68.19

Gene sequence:

>1905_bases
ATGTACGACCTGCTGAAAACCATCGACGATCCGGCGGATCTGCGCCGCCTCGATCGCCGCCAACTGCAACCGCTCGCCGA
CGAGCTGCGCGCCTTCGTGCTCGACAGCGTGTCGAAGACGGGTGGCCATTTGTCGTCCAACCTCGGCACCGTCGAACTGA
CGCTGGCGTTGCACTACGTGTTCAACACGCCGGACGATCGCATCGTGTGGGATGTCGGCCACCAGACCTATCCTCACAAG
ATCCTGACCGGCCGTCGCGAGCAGATGGCCACGCTGCGCCAGTTCGACGGCATCTCGGGCTTCCCGCGCCGCTCGGAGTC
GGTCTACGACACGTTCGGCACCGCGCACTCGAGCACCTCGATCTCGGCCGCGCTCGGCATGGCGATCGGCAGCCAGCTGA
ACGGCGACGACCGGTTCTCGATCGCCGTGATCGGTGACGGCGCGATGACGGCCGGCATGGCCTTCGAGGCGATGAACAAC
GCCGGCGTGTCGGAGCATGCCAAGCTGCTCGTGATCCTCAACGACAACGACATGTCGATCTCGCCGCCCGTGGGCGCGCT
CAACCGCCATCTCGCGCGCCTGATGTCGGGCCGCTTCTACGCGGCCGCGCGCGCCGGCGTGGAGCGCGTGCTGAGCGTCG
CGCCGCCCGTGCTCGAACTCGCGCGCAAGCTCGAGGAGCACGCCAAGGGCATGGTCGTGCCGGCCACGCTGTTCGAGGAG
TTCGGCTTCAACTACATCGGCCCGATCGACGGTCACGACCTCGATTCGCTGATCCCGACGCTGCAGAACATCAAGGAACT
GCGCGGCCCGCAGTTCCTGCACGTGGTCACGAAGAAGGGCCAGGGCTACAAGCTCGCCGAGGCCGACCCGGTGCTCTACC
ACGGCCCGGGCAAGTTCAACCCGGCCGAAGGCATCAAGCCGTCGGCGGCGCCCGCCAAGAAGACCTACACGCAGGTGTTC
GGCGAGTGGCTTTGCGACATGGCCGAGCTCGATGCGCGGGTGGTCGGCATCACGCCGGCGATGCGCGAGGGCTCGGGCAT
GGTCGAGTTCGAGAAGCGCTTCCCCGCGCGCTACTACGACGTCGGCATCGCCGAGCAGCACGCCGTGACGTTCGCGGGCG
GCCTCGCCACCGAAGGGCTCAAGCCGGTGGTGGCGATCTATTCGACGTTCCTGCAGCGCGCCTACGATCAGTTGATCCAC
GACATCGCGCTGCAGAACCTGCCGGTGGTGTTCGCGATCGACCGGGCCGGCCTGGTCGGCGCCGACGGCGCGACGCACGC
GGGCGCCTACGATCTCGCGTTTCTGCGCTGCATCCCGAACATGACCGTCATGGCCGCGTCCGACGAGGACGAGTGCCGTC
AGATGCTCTACACGGCGGTGCAGCAGCCCAACCCGACGGCGGTGCGCTATCCGCGCGGCGCCGGTGCCGGCGTGCCCACC
GTGAAGGCGATGACGGCGCTGCCGGTCGGCAAGGGCGAAGTGCGCCGCCGTTCGGCGCAGCCCGAGGGCAAGCGCGTGGC
GATCCTCGCGTTCGGCACGATGGTCGCGCCGTCGCTCGCGGCGGCCGAGCAGATCGACGCCACCGTGGCCAACATGCGCT
TCGTGAAGCCGGTGGACGCGGAGCTGATCCGCGAGCTCGCCGAGACGCACGACTACCTCGTGACGGTCGAGGAAGGCTGC
GTGCAGGGCGGGGCCGGTTCGGCCTGCGTGGAAGCCCTGATGGAAAGTGGGGTTATCCGGCCCGTACTACAATTGGGCCT
GCCCGATCGCTTCATCGATCATGGCGAGCCGGCCAAGCTGCTGTCGCTGTGCGGCCTCGATGCGGCGGGCATCGCGAAGT
CGATTCGCGAGCGTTTCCTGAGCCAGTCCGCCGAGCTTGCCCGGCAGGCGAAGCGGGTGGCCTGA

Upstream 100 bases:

>100_bases
AACCGGGTCAGCTGACGCGAAAGCCCGCCGCCGCGCCTGGCCTTGCAAGAAGGCGCGCGAAGGAGTGCGGGCGCGTTTGA
TTTCCTACAATGGAACGACG

Downstream 100 bases:

>100_bases
CGCAGTGGACGGCTGGGCCGCCGGGCGGCCTGGCCGTCGTGTCCGGAACTGGCGTCCGGATCCGAAAACATGGGCCTGCG
GGCCCATGTTGCATTTCCGG

Product: 1-deoxy-D-xylulose-5-phosphate synthase

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MYDLLKTIDDPADLRRLDRRQLQPLADELRAFVLDSVSKTGGHLSSNLGTVELTLALHYVFNTPDDRIVWDVGHQTYPHK
ILTGRREQMATLRQFDGISGFPRRSESVYDTFGTAHSSTSISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNN
AGVSEHAKLLVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPVLELARKLEEHAKGMVVPATLFEE
FGFNYIGPIDGHDLDSLIPTLQNIKELRGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFNPAEGIKPSAAPAKKTYTQVF
GEWLCDMAELDARVVGITPAMREGSGMVEFEKRFPARYYDVGIAEQHAVTFAGGLATEGLKPVVAIYSTFLQRAYDQLIH
DIALQNLPVVFAIDRAGLVGADGATHAGAYDLAFLRCIPNMTVMAASDEDECRQMLYTAVQQPNPTAVRYPRGAGAGVPT
VKAMTALPVGKGEVRRRSAQPEGKRVAILAFGTMVAPSLAAAEQIDATVANMRFVKPVDAELIRELAETHDYLVTVEEGC
VQGGAGSACVEALMESGVIRPVLQLGLPDRFIDHGEPAKLLSLCGLDAAGIAKSIRERFLSQSAELARQAKRVA

Sequences:

>Translated_634_residues
MYDLLKTIDDPADLRRLDRRQLQPLADELRAFVLDSVSKTGGHLSSNLGTVELTLALHYVFNTPDDRIVWDVGHQTYPHK
ILTGRREQMATLRQFDGISGFPRRSESVYDTFGTAHSSTSISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNN
AGVSEHAKLLVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPVLELARKLEEHAKGMVVPATLFEE
FGFNYIGPIDGHDLDSLIPTLQNIKELRGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFNPAEGIKPSAAPAKKTYTQVF
GEWLCDMAELDARVVGITPAMREGSGMVEFEKRFPARYYDVGIAEQHAVTFAGGLATEGLKPVVAIYSTFLQRAYDQLIH
DIALQNLPVVFAIDRAGLVGADGATHAGAYDLAFLRCIPNMTVMAASDEDECRQMLYTAVQQPNPTAVRYPRGAGAGVPT
VKAMTALPVGKGEVRRRSAQPEGKRVAILAFGTMVAPSLAAAEQIDATVANMRFVKPVDAELIRELAETHDYLVTVEEGC
VQGGAGSACVEALMESGVIRPVLQLGLPDRFIDHGEPAKLLSLCGLDAAGIAKSIRERFLSQSAELARQAKRVA
>Mature_634_residues
MYDLLKTIDDPADLRRLDRRQLQPLADELRAFVLDSVSKTGGHLSSNLGTVELTLALHYVFNTPDDRIVWDVGHQTYPHK
ILTGRREQMATLRQFDGISGFPRRSESVYDTFGTAHSSTSISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNN
AGVSEHAKLLVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPVLELARKLEEHAKGMVVPATLFEE
FGFNYIGPIDGHDLDSLIPTLQNIKELRGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFNPAEGIKPSAAPAKKTYTQVF
GEWLCDMAELDARVVGITPAMREGSGMVEFEKRFPARYYDVGIAEQHAVTFAGGLATEGLKPVVAIYSTFLQRAYDQLIH
DIALQNLPVVFAIDRAGLVGADGATHAGAYDLAFLRCIPNMTVMAASDEDECRQMLYTAVQQPNPTAVRYPRGAGAGVPT
VKAMTALPVGKGEVRRRSAQPEGKRVAILAFGTMVAPSLAAAEQIDATVANMRFVKPVDAELIRELAETHDYLVTVEEGC
VQGGAGSACVEALMESGVIRPVLQLGLPDRFIDHGEPAKLLSLCGLDAAGIAKSIRERFLSQSAELARQAKRVA

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) [H]

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=638, Percent_Identity=24.1379310344828, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4507521, Length=638, Percent_Identity=24.1379310344828, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI225637463, Length=309, Percent_Identity=25.2427184466019, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI225637459, Length=309, Percent_Identity=25.2427184466019, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI225637461, Length=309, Percent_Identity=25.2427184466019, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI133778974, Length=427, Percent_Identity=24.824355971897, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI156564403, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1786622, Length=616, Percent_Identity=56.8181818181818, Blast_Score=731, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=661, Percent_Identity=23.9031770045386, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538422, Length=249, Percent_Identity=26.5060240963855, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319698, Length=309, Percent_Identity=26.537216828479, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24666278, Length=645, Percent_Identity=25.4263565891473, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45551847, Length=667, Percent_Identity=24.287856071964, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45550715, Length=667, Percent_Identity=24.287856071964, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24645119, Length=580, Percent_Identity=24.6551724137931, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21358145, Length=246, Percent_Identity=28.0487804878049, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650940, Length=246, Percent_Identity=28.0487804878049, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005477
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.7 [H]

Molecular weight: Translated: 68433; Mature: 68433

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLLKTIDDPADLRRLDRRQLQPLADELRAFVLDSVSKTGGHLSSNLGTVELTLALHYV
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEE
FNTPDDRIVWDVGHQTYPHKILTGRREQMATLRQFDGISGFPRRSESVYDTFGTAHSSTS
ECCCCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCH
ISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEHAKLLVILNDNDMSI
HHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
SPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPVLELARKLEEHAKGMVVPATLFEE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEHHHHHHH
FGFNYIGPIDGHDLDSLIPTLQNIKELRGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFN
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCEEEECCCCCC
PAEGIKPSAAPAKKTYTQVFGEWLCDMAELDARVVGITPAMREGSGMVEFEKRFPARYYD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHCCCCCCHHHHHCCCHHEE
VGIAEQHAVTFAGGLATEGLKPVVAIYSTFLQRAYDQLIHDIALQNLPVVFAIDRAGLVG
CCCCCHHHHEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEC
ADGATHAGAYDLAFLRCIPNMTVMAASDEDECRQMLYTAVQQPNPTAVRYPRGAGAGVPT
CCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCH
VKAMTALPVGKGEVRRRSAQPEGKRVAILAFGTMVAPSLAAAEQIDATVANMRFVKPVDA
HHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCEECCCCCH
ELIRELAETHDYLVTVEEGCVQGGAGSACVEALMESGVIRPVLQLGLPDRFIDHGEPAKL
HHHHHHHHCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHH
LSLCGLDAAGIAKSIRERFLSQSAELARQAKRVA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYDLLKTIDDPADLRRLDRRQLQPLADELRAFVLDSVSKTGGHLSSNLGTVELTLALHYV
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEE
FNTPDDRIVWDVGHQTYPHKILTGRREQMATLRQFDGISGFPRRSESVYDTFGTAHSSTS
ECCCCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCH
ISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEHAKLLVILNDNDMSI
HHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
SPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPVLELARKLEEHAKGMVVPATLFEE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEHHHHHHH
FGFNYIGPIDGHDLDSLIPTLQNIKELRGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFN
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCEEEECCCCCC
PAEGIKPSAAPAKKTYTQVFGEWLCDMAELDARVVGITPAMREGSGMVEFEKRFPARYYD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHCCCCCCHHHHHCCCHHEE
VGIAEQHAVTFAGGLATEGLKPVVAIYSTFLQRAYDQLIHDIALQNLPVVFAIDRAGLVG
CCCCCHHHHEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEC
ADGATHAGAYDLAFLRCIPNMTVMAASDEDECRQMLYTAVQQPNPTAVRYPRGAGAGVPT
CCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCH
VKAMTALPVGKGEVRRRSAQPEGKRVAILAFGTMVAPSLAAAEQIDATVANMRFVKPVDA
HHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCEECCCCCH
ELIRELAETHDYLVTVEEGCVQGGAGSACVEALMESGVIRPVLQLGLPDRFIDHGEPAKL
HHHHHHHHCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHH
LSLCGLDAAGIAKSIRERFLSQSAELARQAKRVA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA