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The map label for this gene is guaA [H]

Identifier: 238024891

GI number: 238024891

Start: 1943020

End: 1943655

Strand: Reverse

Name: guaA [H]

Synonym: bglu_2g15340

Alternate gene names: 238024891

Gene position: 1943655-1943020 (Counterclockwise)

Preceding gene: 238024892

Following gene: 238024888

Centisome position: 68.75

GC content: 68.08

Gene sequence:

>636_bases
GTGACGCAACACAATCCGGGGCTGATTCACGATCGGCATGGCGTGCCGCGCTGCTATTGGCAGCCGGACATGCCCGACTA
TCACGACGCCGAATGGGGCCTGCCGGTGGACGACGAACGGCGGCTGTTCGAGAAGATCTGCCTGGAAGGCTTCCAGTCCG
GCATGGCCTGGATCACGATCCTGCGCAAGCGCGAGAACTTCCGCGCGGCGTTCGACGATTTCGATTTCCGGCGCATCGCC
GGCTACGGCGAACCCGACATCGAGCGCCTGATGGCCGATGCCGGCATCGTGCGCAATCGCGCCAAGATCCGCTCGGTGAT
CAACAACGCGCGGCGTGCCATCGAGGCCGTGGACGCATTCGGTTCGCTGGCCGGCTGGCTCTGGCAATACGAGCCGGCGC
CGGGTGCGCGGCCCGCCACGATCGATCTCGACTACTGGCGGGGCAACCCGACCTCGCCCGAGTCGCATGCGCTGTCGGCG
GCGATGAAGCGGCGCGGCTGGACCTTCGTCGGGCCGACCAACATCCATGCGCTGATGCAGGCGGTCGGCATGGTCAACGA
TCACCTGACGGGCTGCGCCTGCCGCGAGACGGTCGAACGCGCGCGCCGCGAGTTCCGGCGGCCGGCCTGCCGCTGA

Upstream 100 bases:

>100_bases
TATTCACGTTCGCGCTGCAGGCGGCCGGGACCGCCGCGCGTTAGCGCCGCCGGTGGCCGGAACTTCAATGGCTATTTCGA
GAACGGGAGCGGACACCAGC

Downstream 100 bases:

>100_bases
GCCGCGCCGCCCGGGCCCGGCCGGCCGCCGGTTTGATCGGCCGGTCGGTCGGCGCGCTGGTCCGTCCCGCTCGGCCGCCT
CGCTCGTCTGCGCCGCTCGG

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTQHNPGLIHDRHGVPRCYWQPDMPDYHDAEWGLPVDDERRLFEKICLEGFQSGMAWITILRKRENFRAAFDDFDFRRIA
GYGEPDIERLMADAGIVRNRAKIRSVINNARRAIEAVDAFGSLAGWLWQYEPAPGARPATIDLDYWRGNPTSPESHALSA
AMKRRGWTFVGPTNIHALMQAVGMVNDHLTGCACRETVERARREFRRPACR

Sequences:

>Translated_211_residues
MTQHNPGLIHDRHGVPRCYWQPDMPDYHDAEWGLPVDDERRLFEKICLEGFQSGMAWITILRKRENFRAAFDDFDFRRIA
GYGEPDIERLMADAGIVRNRAKIRSVINNARRAIEAVDAFGSLAGWLWQYEPAPGARPATIDLDYWRGNPTSPESHALSA
AMKRRGWTFVGPTNIHALMQAVGMVNDHLTGCACRETVERARREFRRPACR
>Mature_210_residues
TQHNPGLIHDRHGVPRCYWQPDMPDYHDAEWGLPVDDERRLFEKICLEGFQSGMAWITILRKRENFRAAFDDFDFRRIAG
YGEPDIERLMADAGIVRNRAKIRSVINNARRAIEAVDAFGSLAGWLWQYEPAPGARPATIDLDYWRGNPTSPESHALSAA
MKRRGWTFVGPTNIHALMQAVGMVNDHLTGCACRETVERARREFRRPACR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=182, Percent_Identity=44.5054945054945, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 24209; Mature: 24078

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHNPGLIHDRHGVPRCYWQPDMPDYHDAEWGLPVDDERRLFEKICLEGFQSGMAWITI
CCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRKRENFRAAFDDFDFRRIAGYGEPDIERLMADAGIVRNRAKIRSVINNARRAIEAVDAF
HHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLAGWLWQYEPAPGARPATIDLDYWRGNPTSPESHALSAAMKRRGWTFVGPTNIHALMQ
HHHHHHHEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHHHH
AVGMVNDHLTGCACRETVERARREFRRPACR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TQHNPGLIHDRHGVPRCYWQPDMPDYHDAEWGLPVDDERRLFEKICLEGFQSGMAWITI
CCCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRKRENFRAAFDDFDFRRIAGYGEPDIERLMADAGIVRNRAKIRSVINNARRAIEAVDAF
HHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLAGWLWQYEPAPGARPATIDLDYWRGNPTSPESHALSAAMKRRGWTFVGPTNIHALMQ
HHHHHHHEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHHHH
AVGMVNDHLTGCACRETVERARREFRRPACR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]