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The map label for this gene is dapA2 [H]

Identifier: 238024872

GI number: 238024872

Start: 1916663

End: 1917559

Strand: Direct

Name: dapA2 [H]

Synonym: bglu_2g15130

Alternate gene names: 238024872

Gene position: 1916663-1917559 (Clockwise)

Preceding gene: 238024871

Following gene: 238024883

Centisome position: 67.79

GC content: 71.68

Gene sequence:

>897_bases
ATGCTCAAGGGCATCTGGCTTCCGCTCGTCACGCCGTTTCGCGGCGGCCGGCTCGATCTGGCCGCGCTCGAAGCGCTGAG
CGCCTCGTACCTCGACACCGGCATCGCCGGCTTCGTCGCACTCGGCACCACGGCCGAGGCCGCGCTGCTCGACGACGCGG
AGCGCGCCGCCGCGCTGAAGACCATCATCGGCGTCGCGGCCGGCCGCTTGCCGGTGTTCGTCGGCGTCGGCGGCATCGAC
ACGCGGGATTTCCTCGACCAGATCGACCGCCTGGAACTGCATGACGTGACCGGCTATCTGGTGCCGCCGCCTGCCTATCT
CTGCCCGAGTCAGGCCGGGCTGCTCTGGCATTTCGGGCAAATCGCGACACGCACGCGGCGCCCCGTGATGCTCTACGACG
TGCCGCATCGCTGCGGCGTGGCGATCGAGCCGGCCACCGTCGGGCAACTGGCACGCCATTCCAACCTCGTCGGCATCAAG
GAATGCGTGCCGGCTCACTTCGAACCACTGCGCGCCGCGCCGCTCGAGGTGCTGTGCGGCACCGACGACGCGTTCGCCGC
CTGCCTCGCGGCAGGCGGTGCAGGCGGCGTGCTGGCGAGCGCGCACGTCTGCGCCGACCTGTTCGTCGAGGTGCAGCAAT
TGCATGAGGCCGGCCGCGTGGCCGAGGCGCAGTCGCGCTTCGAGGCGCTACGGCCGGTGCTGCAGCTGCTGTTCTCGGCG
CCGAATCCGGCCGCGATCAAGGCGATGCTGTCGCTCACGCACGGCATCACGGCCGAGGTGCGCATGCCGATCACGCCGGC
TTCGCCGCCGCTCGTGACCGCGCTGCGGCACGCGCGGGCCGCGCTGGAGCGCCTGCGCGCCGAGCGGCCGACATCGCTCG
GCGCATCAGCCGCGTGA

Upstream 100 bases:

>100_bases
CGGGTCAAGGTCCATCGCATGAGCCACCGTCAGGCCGCCGTTCCTCCTTCCCACTCCCGCCCGCACGGCACCGTGGTCGG
TCAACGCGGGAGGCACTGAC

Downstream 100 bases:

>100_bases
CGCCGCGCCCGCGCGGGTCGGCTGCCGCGTCCGATGGGTCAGCGCAAACCAGGCGGATTCGCGCTTGCAGACCGGTCCGG
CAGGCGCAAACGAAACGACT

Product: putative dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS 2 [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLKGIWLPLVTPFRGGRLDLAALEALSASYLDTGIAGFVALGTTAEAALLDDAERAAALKTIIGVAAGRLPVFVGVGGID
TRDFLDQIDRLELHDVTGYLVPPPAYLCPSQAGLLWHFGQIATRTRRPVMLYDVPHRCGVAIEPATVGQLARHSNLVGIK
ECVPAHFEPLRAAPLEVLCGTDDAFAACLAAGGAGGVLASAHVCADLFVEVQQLHEAGRVAEAQSRFEALRPVLQLLFSA
PNPAAIKAMLSLTHGITAEVRMPITPASPPLVTALRHARAALERLRAERPTSLGASAA

Sequences:

>Translated_298_residues
MLKGIWLPLVTPFRGGRLDLAALEALSASYLDTGIAGFVALGTTAEAALLDDAERAAALKTIIGVAAGRLPVFVGVGGID
TRDFLDQIDRLELHDVTGYLVPPPAYLCPSQAGLLWHFGQIATRTRRPVMLYDVPHRCGVAIEPATVGQLARHSNLVGIK
ECVPAHFEPLRAAPLEVLCGTDDAFAACLAAGGAGGVLASAHVCADLFVEVQQLHEAGRVAEAQSRFEALRPVLQLLFSA
PNPAAIKAMLSLTHGITAEVRMPITPASPPLVTALRHARAALERLRAERPTSLGASAA
>Mature_298_residues
MLKGIWLPLVTPFRGGRLDLAALEALSASYLDTGIAGFVALGTTAEAALLDDAERAAALKTIIGVAAGRLPVFVGVGGID
TRDFLDQIDRLELHDVTGYLVPPPAYLCPSQAGLLWHFGQIATRTRRPVMLYDVPHRCGVAIEPATVGQLARHSNLVGIK
ECVPAHFEPLRAAPLEVLCGTDDAFAACLAAGGAGGVLASAHVCADLFVEVQQLHEAGRVAEAQSRFEALRPVLQLLFSA
PNPAAIKAMLSLTHGITAEVRMPITPASPPLVTALRHARAALERLRAERPTSLGASAA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=292, Percent_Identity=24.6575342465753, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788823, Length=289, Percent_Identity=32.5259515570934, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786463, Length=282, Percent_Identity=30.1418439716312, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082415, Length=297, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31316; Mature: 31316

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGIWLPLVTPFRGGRLDLAALEALSASYLDTGIAGFVALGTTAEAALLDDAERAAALK
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TIIGVAAGRLPVFVGVGGIDTRDFLDQIDRLELHDVTGYLVPPPAYLCPSQAGLLWHFGQ
HHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCHHHCCCEECCCCCCCCCCCCCHHHHHHH
IATRTRRPVMLYDVPHRCGVAIEPATVGQLARHSNLVGIKECVPAHFEPLRAAPLEVLCG
HHHHCCCCEEEEECCCCCCCEECCHHHHHHHHHCCCCCHHHHCCHHCCCHHCCCEEEEEC
TDDAFAACLAAGGAGGVLASAHVCADLFVEVQQLHEAGRVAEAQSRFEALRPVLQLLFSA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PNPAAIKAMLSLTHGITAEVRMPITPASPPLVTALRHARAALERLRAERPTSLGASAA
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLKGIWLPLVTPFRGGRLDLAALEALSASYLDTGIAGFVALGTTAEAALLDDAERAAALK
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TIIGVAAGRLPVFVGVGGIDTRDFLDQIDRLELHDVTGYLVPPPAYLCPSQAGLLWHFGQ
HHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCHHHCCCEECCCCCCCCCCCCCHHHHHHH
IATRTRRPVMLYDVPHRCGVAIEPATVGQLARHSNLVGIKECVPAHFEPLRAAPLEVLCG
HHHHCCCCEEEEECCCCCCCEECCHHHHHHHHHCCCCCHHHHCCHHCCCHHCCCEEEEEC
TDDAFAACLAAGGAGGVLASAHVCADLFVEVQQLHEAGRVAEAQSRFEALRPVLQLLFSA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PNPAAIKAMLSLTHGITAEVRMPITPASPPLVTALRHARAALERLRAERPTSLGASAA
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]