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The map label for this gene is alsR [H]

Identifier: 238024871

GI number: 238024871

Start: 1915522

End: 1916415

Strand: Direct

Name: alsR [H]

Synonym: bglu_2g15120

Alternate gene names: 238024871

Gene position: 1915522-1916415 (Clockwise)

Preceding gene: 238024870

Following gene: 238024872

Centisome position: 67.75

GC content: 72.04

Gene sequence:

>894_bases
ATGGAACTGAAACACCTCGTCGCCTTCGTCGCGCTTGCCGAGGAACTGCACTTCGGCCGCGCGGCCGGGCGCCTCTGCAT
CGTGCAGCCCGCGCTGAGCATGCAGATCAAGGCGCTCGAGACGGCTCTCGGCGTGCGGCTGTTCGATCGCGACCGTCACA
AGGTGGCACTGAGCACCGCGGGCAGCCTGTTCCTGCCCGAGGCGCGCGCCACGCTCGAACAGGCCGCCCGCGCCGCGCAG
GTCGCACGGCTGTCGGCGCAGGGAGAGATCGGGACGCTGCGGCTCGGCTTCGTCTCGTCGGTGCTGCCGAAGTTGCTGCC
GACGCTGATCCGCACCATGCATGCGCGCTACCCGCGTATCGCGCTCGATCTGAAGGACATGCCGACGCCGGACCAGATCG
CCGCGCTGCAGGGCGGCACGCTCGACTTCGGCATCGCGCGGCTGCCGGTTGCCGCCAGCGGCCTGGCCTCGCGCGTGGTG
CTGGAAGAATCGTTCGTGGTGGCCGTGCCGGCCTCGCACGCGCTCGCCCGGCAGACGCAAATCGAGCCGGCACAGCTGCG
CGGCCAGCACGCCTTCGTGCTCGCGCGCCGCTACGCGCCCGGCTTCTTCGACGCGTTGCTGGTGGCGCTCGGCGCGCGCG
GGGTCACGCTCGACATCGCACGCGAACTCGGCGAATACACCACCATGCTCGCGCTCGTCGCGGCCGGCCTCGGGATCGGC
CTGATCCCCGCCGAGGCGGCCGCGGCCGTGCCGCCGAACGTGGTCGCGCGGCCGCTGGCGCTGCCCTCGCATCGCGCGCT
GCTCGGCCTGATCTGGGTCGAGGACGGCAGCGCCCTCAAGCACGTGTTCCTCGACGTGGTGGAACAGGGCACGGCGAACG
GCTGGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCGTGCCGCCGCAACGCTCCGCCTCGATTCGCCCGTTGTCGGCGCACCGCGCCCGGCCTAACATGCCGGCATCCTGATT
TCGCCCGTCGTCACGATCGG

Downstream 100 bases:

>100_bases
GCAAACACCGGCGCGCCGCGGGCGGCCAGCACCGGCATCCGGTCCCGCGGGCGGCCCCAGCCGCCCCTTGCTGATGCGAG
CCGTCCGGTTTTTTTATACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MELKHLVAFVALAEELHFGRAAGRLCIVQPALSMQIKALETALGVRLFDRDRHKVALSTAGSLFLPEARATLEQAARAAQ
VARLSAQGEIGTLRLGFVSSVLPKLLPTLIRTMHARYPRIALDLKDMPTPDQIAALQGGTLDFGIARLPVAASGLASRVV
LEESFVVAVPASHALARQTQIEPAQLRGQHAFVLARRYAPGFFDALLVALGARGVTLDIARELGEYTTMLALVAAGLGIG
LIPAEAAAAVPPNVVARPLALPSHRALLGLIWVEDGSALKHVFLDVVEQGTANGWAA

Sequences:

>Translated_297_residues
MELKHLVAFVALAEELHFGRAAGRLCIVQPALSMQIKALETALGVRLFDRDRHKVALSTAGSLFLPEARATLEQAARAAQ
VARLSAQGEIGTLRLGFVSSVLPKLLPTLIRTMHARYPRIALDLKDMPTPDQIAALQGGTLDFGIARLPVAASGLASRVV
LEESFVVAVPASHALARQTQIEPAQLRGQHAFVLARRYAPGFFDALLVALGARGVTLDIARELGEYTTMLALVAAGLGIG
LIPAEAAAAVPPNVVARPLALPSHRALLGLIWVEDGSALKHVFLDVVEQGTANGWAA
>Mature_297_residues
MELKHLVAFVALAEELHFGRAAGRLCIVQPALSMQIKALETALGVRLFDRDRHKVALSTAGSLFLPEARATLEQAARAAQ
VARLSAQGEIGTLRLGFVSSVLPKLLPTLIRTMHARYPRIALDLKDMPTPDQIAALQGGTLDFGIARLPVAASGLASRVV
LEESFVVAVPASHALARQTQIEPAQLRGQHAFVLARRYAPGFFDALLVALGARGVTLDIARELGEYTTMLALVAAGLGIG
LIPAEAAAAVPPNVVARPLALPSHRALLGLIWVEDGSALKHVFLDVVEQGTANGWAA

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=245, Percent_Identity=38.7755102040816, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1788887, Length=295, Percent_Identity=34.9152542372881, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367136, Length=263, Percent_Identity=34.6007604562738, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790399, Length=301, Percent_Identity=32.890365448505, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693105, Length=277, Percent_Identity=32.129963898917, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=32.9317269076305, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI157672245, Length=196, Percent_Identity=32.6530612244898, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787806, Length=275, Percent_Identity=28.3636363636364, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081904, Length=181, Percent_Identity=30.939226519337, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790262, Length=243, Percent_Identity=26.7489711934156, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=25.6916996047431, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789506, Length=253, Percent_Identity=23.7154150197628, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=32.1917808219178, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787530, Length=265, Percent_Identity=28.6792452830189, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788481, Length=242, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=254, Percent_Identity=24.8031496062992, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789204, Length=282, Percent_Identity=25.531914893617, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31448; Mature: 31448

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKHLVAFVALAEELHFGRAAGRLCIVQPALSMQIKALETALGVRLFDRDRHKVALSTA
CCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEECC
GSLFLPEARATLEQAARAAQVARLSAQGEIGTLRLGFVSSVLPKLLPTLIRTMHARYPRI
CCEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEE
ALDLKDMPTPDQIAALQGGTLDFGIARLPVAASGLASRVVLEESFVVAVPASHALARQTQ
EEECCCCCCCHHHHHHCCCCCCCCHHHCCHHHHHHHHHHEEECCEEEEECCHHHHHHHCC
IEPAQLRGQHAFVLARRYAPGFFDALLVALGARGVTLDIARELGEYTTMLALVAAGLGIG
CCHHHHCCCHHEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
LIPAEAAAAVPPNVVARPLALPSHRALLGLIWVEDGSALKHVFLDVVEQGTANGWAA
CCCCCHHHCCCCHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MELKHLVAFVALAEELHFGRAAGRLCIVQPALSMQIKALETALGVRLFDRDRHKVALSTA
CCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEECC
GSLFLPEARATLEQAARAAQVARLSAQGEIGTLRLGFVSSVLPKLLPTLIRTMHARYPRI
CCEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEE
ALDLKDMPTPDQIAALQGGTLDFGIARLPVAASGLASRVVLEESFVVAVPASHALARQTQ
EEECCCCCCCHHHHHHCCCCCCCCHHHCCHHHHHHHHHHEEECCEEEEECCHHHHHHHCC
IEPAQLRGQHAFVLARRYAPGFFDALLVALGARGVTLDIARELGEYTTMLALVAAGLGIG
CCHHHHCCCHHEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
LIPAEAAAAVPPNVVARPLALPSHRALLGLIWVEDGSALKHVFLDVVEQGTANGWAA
CCCCCHHHCCCCHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]