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The map label for this gene is aaeB [H]

Identifier: 238024606

GI number: 238024606

Start: 1556802

End: 1558940

Strand: Direct

Name: aaeB [H]

Synonym: bglu_2g12210

Alternate gene names: 238024606

Gene position: 1556802-1558940 (Clockwise)

Preceding gene: 238024605

Following gene: 238024607

Centisome position: 55.06

GC content: 72.04

Gene sequence:

>2139_bases
ATGAGCTATCCGTCGATCCGCGACTGGCTGTTCTCGACCAAGACCTTCGCGGCGTCGATGCTCGCGCTCTATCTCGGCCT
CTATTTCCAGCTGCCGCGCCCCTACTGGGCGATGGCCAGCGTCTATATCGTCTCGAACCCGTTCGTCGGCGCCACGCGCT
CGAAGGCGCTGTACCGCGTGCTGGGCACCGCGCTCGGCGCGGCCGCGGCGATCCTGCTGGTGCCGCCCTTCGTCGAGACG
CCGTTCCTGTTCAGCGTGATCGTCGCGCTCTGGACCGGCACCCTCCTCTATCTGGCGATCTCCGATCGCACCGCGCGCAG
CTACGTGTTCATGCTGGCCGGCTATACGATGCCGCTGATCGCGCTGCCCACCGTGACCGATCCCGCCACGGTGTTCGACG
TCGCGATCGCGCGCACCGAGGAGATCACGCTCGGCATCGTCTGCGCGAGCGTGGTGGGCAGCGCGATCCTGCCGAACCGG
CTCGCGCCGACGCTGATCGAGCGCACCGACGCCTGGTTTCGCGACGCGGCGTTCTACGGCCGCGAAACGCTGTCGGGCCA
TCTGGCCGGCAAGGCGCTGTCCGCCTGCCGGCAGCGGCTCGCCTCCACCGTCTCCGCGCTGGAATTCCTGCTGAGCCAGC
TCGGCTACGATCATTCGTCGCCGCGCGTGCTCGCGCGCGCCGAGGCGCTGCGCGGGCGCATGCAGCTGTTCCTGCCGCTG
ATGTCGGCGCTGGCCGATCCGCTCGTCGCGCTGATGCGGGAGCTCGAGCAGTTGCCGGCCGAGCTCGAGGCACTGCTGGC
CGACGCGGCCCGCTGGTTCGACGCGCCGCTGCCGAGCGCCTCGGAGGCCAGCGGCGGCGTCCACGAACCGGAGGCCGACC
GGCTGCGCGCGCGGATCGCGGCGCTGCAGCCGCGCGGCGCGGCGCTCACGCGCTGGGACGGCGCGCTGCTGTCGAACGCG
CTGTGGCGGCTGCGCCAGGTGATCGACGTGTGGCAGGACTGCCGCGCGCTGCGCGCGCTGATCGCCAACGAATCGGGGGT
CTGGCAGCCGCGCTACCGGCACTGGCGGATCGGCGGCACCGAGCGCTATTTCGATCGCGGCATGATGCTGTTCTCCACGC
TGAGCGCGGGCGGCGCCATCGTGTTCGCGTGCTGGCTGTGGATCTCGTCGGGCTGGGCCGACGGCGCGGGCGCGGTCACG
CTGGCGGCGGTGGCCTGCTGCTTCTTCGCCGCGCTCGACGAACCGGCGCCGATGGTGTTCCGCTTCTTCACCGCCACCTG
CGCGAGCGTGGTGCTGGCCGGCCTCTACCTGTTCCTGGTGCTGCCGCACGTGCACGACTTCGCGATGCTGGTGGTGATGT
TCGCCGGGCCGTTCATCCTGATCGGCACGCTGATCCCGCGCCCGCAGTTCAATCTCGTGACGATGCTGGTGGCCGTCAAC
ACCGCCACCTTCATCAGCATCCAGGACGCCTACCAGGCCGACTTCCTGATCTTCCTGAACAGCAACATCGCCGGCGTGGC
GGGGTTGCTGTTCGCGTTCGTCTGGACCCGCGCGACGCGCCCGTTCGGCGCCGAACTCGCGGTGCGGCGGCTGCTGCGCT
CGAGCTGGCAGGACGTGGCGAAATCGGCCTCGGCGCAGCCGGTGCGCGACCAGCGCAACCACGCCTCGCGGATGCTCGAC
CGCGTCACCCAGCTGCTGCCGCGGCTGGCCGCCTCCGACGATCACCGCCATCCGTCGATCGAATCGTTCCGCGACCTGCG
CGTGGCGCTCAACGCGCTCGATCTGCAGCGCACGCGGCGCCGGCTCGGCGGCGAGCTGCCGGCCGCGATCGACCGCGTGC
TCGACGGCGTCAACGCGCATTTCACCGCCTGCGCCGACGCGAACGCGCGCCAGCCGGTGCCGCCCGCGCTGCTGGCCTCG
ATCGAGGCGGCGCTCGAGCGCCTGGCGCTGCGCCAGCCGGGCCAGGACGGCGCCTCGGCCGGCACCGAATCCGGCACCGC
GCCGCGCGAGGCGCGCCCGGCCGCCGCGCTGCAGCGCGGGCTGCGCGACGCGCTGCATGCGCTGGTGGGCCTGCGGCTGT
CGCTCAATCCCCTGCTGATGCAGCCCAAGCCGCCCGCAGCCGACGCCGCGCGGGCCTGA

Upstream 100 bases:

>100_bases
GCGCCAGGGTGCTGAAATCGGTCAGCCGCGCCGACCTGGAAGCCACGCTGCGCGTGCTGGCCGCCTTCAACGAGGCGGGA
AACCGCGATCACGCCGCCTC

Downstream 100 bases:

>100_bases
GCCGGCGCCTCCCCGTCCAACCCCAGGCAACCATGATCGGCGAACTCGACATCTTCGGCGTCTACGTACCCGCACCGCTG
GTGCTGATGCTGATCGCCTA

Product: putative fusaric acid resistance transporter protein

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MSYPSIRDWLFSTKTFAASMLALYLGLYFQLPRPYWAMASVYIVSNPFVGATRSKALYRVLGTALGAAAAILLVPPFVET
PFLFSVIVALWTGTLLYLAISDRTARSYVFMLAGYTMPLIALPTVTDPATVFDVAIARTEEITLGIVCASVVGSAILPNR
LAPTLIERTDAWFRDAAFYGRETLSGHLAGKALSACRQRLASTVSALEFLLSQLGYDHSSPRVLARAEALRGRMQLFLPL
MSALADPLVALMRELEQLPAELEALLADAARWFDAPLPSASEASGGVHEPEADRLRARIAALQPRGAALTRWDGALLSNA
LWRLRQVIDVWQDCRALRALIANESGVWQPRYRHWRIGGTERYFDRGMMLFSTLSAGGAIVFACWLWISSGWADGAGAVT
LAAVACCFFAALDEPAPMVFRFFTATCASVVLAGLYLFLVLPHVHDFAMLVVMFAGPFILIGTLIPRPQFNLVTMLVAVN
TATFISIQDAYQADFLIFLNSNIAGVAGLLFAFVWTRATRPFGAELAVRRLLRSSWQDVAKSASAQPVRDQRNHASRMLD
RVTQLLPRLAASDDHRHPSIESFRDLRVALNALDLQRTRRRLGGELPAAIDRVLDGVNAHFTACADANARQPVPPALLAS
IEAALERLALRQPGQDGASAGTESGTAPREARPAAALQRGLRDALHALVGLRLSLNPLLMQPKPPAADAARA

Sequences:

>Translated_712_residues
MSYPSIRDWLFSTKTFAASMLALYLGLYFQLPRPYWAMASVYIVSNPFVGATRSKALYRVLGTALGAAAAILLVPPFVET
PFLFSVIVALWTGTLLYLAISDRTARSYVFMLAGYTMPLIALPTVTDPATVFDVAIARTEEITLGIVCASVVGSAILPNR
LAPTLIERTDAWFRDAAFYGRETLSGHLAGKALSACRQRLASTVSALEFLLSQLGYDHSSPRVLARAEALRGRMQLFLPL
MSALADPLVALMRELEQLPAELEALLADAARWFDAPLPSASEASGGVHEPEADRLRARIAALQPRGAALTRWDGALLSNA
LWRLRQVIDVWQDCRALRALIANESGVWQPRYRHWRIGGTERYFDRGMMLFSTLSAGGAIVFACWLWISSGWADGAGAVT
LAAVACCFFAALDEPAPMVFRFFTATCASVVLAGLYLFLVLPHVHDFAMLVVMFAGPFILIGTLIPRPQFNLVTMLVAVN
TATFISIQDAYQADFLIFLNSNIAGVAGLLFAFVWTRATRPFGAELAVRRLLRSSWQDVAKSASAQPVRDQRNHASRMLD
RVTQLLPRLAASDDHRHPSIESFRDLRVALNALDLQRTRRRLGGELPAAIDRVLDGVNAHFTACADANARQPVPPALLAS
IEAALERLALRQPGQDGASAGTESGTAPREARPAAALQRGLRDALHALVGLRLSLNPLLMQPKPPAADAARA
>Mature_711_residues
SYPSIRDWLFSTKTFAASMLALYLGLYFQLPRPYWAMASVYIVSNPFVGATRSKALYRVLGTALGAAAAILLVPPFVETP
FLFSVIVALWTGTLLYLAISDRTARSYVFMLAGYTMPLIALPTVTDPATVFDVAIARTEEITLGIVCASVVGSAILPNRL
APTLIERTDAWFRDAAFYGRETLSGHLAGKALSACRQRLASTVSALEFLLSQLGYDHSSPRVLARAEALRGRMQLFLPLM
SALADPLVALMRELEQLPAELEALLADAARWFDAPLPSASEASGGVHEPEADRLRARIAALQPRGAALTRWDGALLSNAL
WRLRQVIDVWQDCRALRALIANESGVWQPRYRHWRIGGTERYFDRGMMLFSTLSAGGAIVFACWLWISSGWADGAGAVTL
AAVACCFFAALDEPAPMVFRFFTATCASVVLAGLYLFLVLPHVHDFAMLVVMFAGPFILIGTLIPRPQFNLVTMLVAVNT
ATFISIQDAYQADFLIFLNSNIAGVAGLLFAFVWTRATRPFGAELAVRRLLRSSWQDVAKSASAQPVRDQRNHASRMLDR
VTQLLPRLAASDDHRHPSIESFRDLRVALNALDLQRTRRRLGGELPAAIDRVLDGVNAHFTACADANARQPVPPALLASI
EAALERLALRQPGQDGASAGTESGTAPREARPAAALQRGLRDALHALVGLRLSLNPLLMQPKPPAADAARA

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=557, Percent_Identity=24.0574506283662, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1787933, Length=157, Percent_Identity=35.6687898089172, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 77516; Mature: 77385

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYPSIRDWLFSTKTFAASMLALYLGLYFQLPRPYWAMASVYIVSNPFVGATRSKALYRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCCCCCHHHHHHHHH
LGTALGAAAAILLVPPFVETPFLFSVIVALWTGTLLYLAISDRTARSYVFMLAGYTMPLI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHHHE
ALPTVTDPATVFDVAIARTEEITLGIVCASVVGSAILPNRLAPTLIERTDAWFRDAAFYG
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RETLSGHLAGKALSACRQRLASTVSALEFLLSQLGYDHSSPRVLARAEALRGRMQLFLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MSALADPLVALMRELEQLPAELEALLADAARWFDAPLPSASEASGGVHEPEADRLRARIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALQPRGAALTRWDGALLSNALWRLRQVIDVWQDCRALRALIANESGVWQPRYRHWRIGGT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCH
ERYFDRGMMLFSTLSAGGAIVFACWLWISSGWADGAGAVTLAAVACCFFAALDEPAPMVF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
RFFTATCASVVLAGLYLFLVLPHVHDFAMLVVMFAGPFILIGTLIPRPQFNLVTMLVAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHH
TATFISIQDAYQADFLIFLNSNIAGVAGLLFAFVWTRATRPFGAELAVRRLLRSSWQDVA
HHHEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KSASAQPVRDQRNHASRMLDRVTQLLPRLAASDDHRHPSIESFRDLRVALNALDLQRTRR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RLGGELPAAIDRVLDGVNAHFTACADANARQPVPPALLASIEAALERLALRQPGQDGASA
HHCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
GTESGTAPREARPAAALQRGLRDALHALVGLRLSLNPLLMQPKPPAADAARA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
SYPSIRDWLFSTKTFAASMLALYLGLYFQLPRPYWAMASVYIVSNPFVGATRSKALYRV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCCCCCHHHHHHHHH
LGTALGAAAAILLVPPFVETPFLFSVIVALWTGTLLYLAISDRTARSYVFMLAGYTMPLI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHHHE
ALPTVTDPATVFDVAIARTEEITLGIVCASVVGSAILPNRLAPTLIERTDAWFRDAAFYG
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RETLSGHLAGKALSACRQRLASTVSALEFLLSQLGYDHSSPRVLARAEALRGRMQLFLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MSALADPLVALMRELEQLPAELEALLADAARWFDAPLPSASEASGGVHEPEADRLRARIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALQPRGAALTRWDGALLSNALWRLRQVIDVWQDCRALRALIANESGVWQPRYRHWRIGGT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCH
ERYFDRGMMLFSTLSAGGAIVFACWLWISSGWADGAGAVTLAAVACCFFAALDEPAPMVF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
RFFTATCASVVLAGLYLFLVLPHVHDFAMLVVMFAGPFILIGTLIPRPQFNLVTMLVAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHH
TATFISIQDAYQADFLIFLNSNIAGVAGLLFAFVWTRATRPFGAELAVRRLLRSSWQDVA
HHHEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KSASAQPVRDQRNHASRMLDRVTQLLPRLAASDDHRHPSIESFRDLRVALNALDLQRTRR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RLGGELPAAIDRVLDGVNAHFTACADANARQPVPPALLASIEAALERLALRQPGQDGASA
HHCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
GTESGTAPREARPAAALQRGLRDALHALVGLRLSLNPLLMQPKPPAADAARA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA