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The map label for this gene is zwf [H]

Identifier: 238024588

GI number: 238024588

Start: 1533830

End: 1535527

Strand: Reverse

Name: zwf [H]

Synonym: bglu_2g11990

Alternate gene names: 238024588

Gene position: 1535527-1533830 (Counterclockwise)

Preceding gene: 238024589

Following gene: 238024587

Centisome position: 54.31

GC content: 71.5

Gene sequence:

>1698_bases
ATGCCGCTCAACGATGCCACCCGCGCCCCCTCCGACCAAGCGCGCCAGCCGGCCGGCGCGAAGGTGCCCGCGCCGTCGCG
CGGCGCGCCCGCGGCGCCGGCCGGCCGGCACCCCGCGCCGCCCTGCACGCTGGTGATCTTCGGCGCCGGCGGTGACCTGA
CGAGCCGGCTGCTGATGCCCGCGCTCTACAACCTCGCGGCGGACGGCCTGCTCGACGAGGGCACGAAGATCATCGGCGTC
AATCACGGCGAGCGCGAGACCGAGGCCTGGCGCGACGATTTACACAGCGCATTGCAAAAGCTCGCCGCCGACAAGGCCAG
CACCTTTCACGCCGGCAAGCTCGACGAGCACGCCTGGCGCTGGGTCGCGCAGCGCCTGCAATACCTGGCCGGCGACTTCG
AGGACGAGGGCACCTACCGGCGTCTCGCGCAGCAGCTCGGCGCAGGCGGGCCCGGCGCCGCGCACGGCAGCGTGGCGTTC
TACCTCGCGGTGAGCGGGCGCTTCTTCAAGCCGATCGTCGAGCGCCTGGGCAAGGCCGGCCTGCTCGAGCAAGCCGGCGA
CGGCGGGCCGTTCCGCCGCGTGGTGATCGAAAAGCCGTTCGGCACCGATCTGGCCTCGGCACGCGACCTGAACCGGCACC
TGCTCGGCTTCATGAAGGAATCGCAGATCTACCGGATCGACCACTTCCTCGGCAAGGAGACGGTGCAGAGCATCCTGGCC
GTGCGCTTCGCCAACGCGCTGTTCGAGCCGATCTGGCGGCGCGAGTACATCGACAGCGTGCAGATCGCGGCTTCCGAGGT
GATCGGCGTCGAGCGCCGCGGCAGCTTCTACGAGCAGACCGGCGCGTTCCGCGACATGGTGCCGAACCATCTGTTCCAAC
TGCTCGGCATGGTCGCGATGGAGCCGCCGAACTCGTTCGACGCGCGGGCCGTGCGCGACAAGAAGGCCGAGGTCTTCGAC
GCGCTGAAGCCGCTCGCGCCGCGCGACGTGGTGTTCGGCCAGTACGCGGCGGGGCCGGGCGGTGCGGCCTATCGCGACGA
GCCCGACGTGGCGCCCGACAGCACGACCGAGACCTACGCGGCGGCGCGCGTGCAGATCGACAACTGGCGCTGGGCCGGCG
TGCCGTTCTACCTGCGCACCGGCAAGCGGCTGGCCGAGCGGCGCACCGAAATCGCCGTGCAGCTGAAACCGGTGCCGTTC
CGGCTGTTCCGCGACACGCCCACCGACGCCCTGACGCCGAACGTGCTGACGCTGCGCATCGACCCCTCGCACGGCACCAG
CTTCGATTTCAACGTGAAGACGCCGGGGCCGGTCATGCGGGTCGGCGCGGTGCGCTCGTCGTTCGATTACGATGCGTTTT
TCCCCGAGCGCGCCAACGTCGGCTACGAGACGCTGCTCTACGATTGCCTGCTCGGCGACGAGACGCTGTTCCAGCGCGCC
GACAGCATCGAATCGACTTGGCAGGCCGCCGAGGGCGTGCTGCACCCGCGTGACGGCGCCGCGATCCCGGTGCAGGCTTA
CCCGGCCGGCAGCGAGGGGCCGGCCGAGGCCGCCGCGCTGATCGAGCGCGACGGGCGCGCGTGGCGGCCGCTCGCGGCGC
GGCAGGCAGGGGCCGAAGCGCAGGCGAAGGCGGCGTCGCATTCCGCTTCGAAGCCGAAGCCGAAGCCGAAGCCGCAGGCG
GACGCCGGCAAGCCGTGA

Upstream 100 bases:

>100_bases
GGGCCGGAACCAGGCGCGTGGCTCGGCCGCCGCGATGGCGCGCCCCGCGCGGGCATCGCGCTTGCTGCCTCGTTGTGTTT
CAGCCGATACGGACGAGATC

Downstream 100 bases:

>100_bases
CGCCCGGCCGATCACGCCGATCACGAGTGGCCGGCGGCGTGTCGCGAGGCCGGCACAACCAGAACCCGCACCACGAGACG
AACTTCATGAAACCGAGCCA

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MPLNDATRAPSDQARQPAGAKVPAPSRGAPAAPAGRHPAPPCTLVIFGAGGDLTSRLLMPALYNLAADGLLDEGTKIIGV
NHGERETEAWRDDLHSALQKLAADKASTFHAGKLDEHAWRWVAQRLQYLAGDFEDEGTYRRLAQQLGAGGPGAAHGSVAF
YLAVSGRFFKPIVERLGKAGLLEQAGDGGPFRRVVIEKPFGTDLASARDLNRHLLGFMKESQIYRIDHFLGKETVQSILA
VRFANALFEPIWRREYIDSVQIAASEVIGVERRGSFYEQTGAFRDMVPNHLFQLLGMVAMEPPNSFDARAVRDKKAEVFD
ALKPLAPRDVVFGQYAAGPGGAAYRDEPDVAPDSTTETYAAARVQIDNWRWAGVPFYLRTGKRLAERRTEIAVQLKPVPF
RLFRDTPTDALTPNVLTLRIDPSHGTSFDFNVKTPGPVMRVGAVRSSFDYDAFFPERANVGYETLLYDCLLGDETLFQRA
DSIESTWQAAEGVLHPRDGAAIPVQAYPAGSEGPAEAAALIERDGRAWRPLAARQAGAEAQAKAASHSASKPKPKPKPQA
DAGKP

Sequences:

>Translated_565_residues
MPLNDATRAPSDQARQPAGAKVPAPSRGAPAAPAGRHPAPPCTLVIFGAGGDLTSRLLMPALYNLAADGLLDEGTKIIGV
NHGERETEAWRDDLHSALQKLAADKASTFHAGKLDEHAWRWVAQRLQYLAGDFEDEGTYRRLAQQLGAGGPGAAHGSVAF
YLAVSGRFFKPIVERLGKAGLLEQAGDGGPFRRVVIEKPFGTDLASARDLNRHLLGFMKESQIYRIDHFLGKETVQSILA
VRFANALFEPIWRREYIDSVQIAASEVIGVERRGSFYEQTGAFRDMVPNHLFQLLGMVAMEPPNSFDARAVRDKKAEVFD
ALKPLAPRDVVFGQYAAGPGGAAYRDEPDVAPDSTTETYAAARVQIDNWRWAGVPFYLRTGKRLAERRTEIAVQLKPVPF
RLFRDTPTDALTPNVLTLRIDPSHGTSFDFNVKTPGPVMRVGAVRSSFDYDAFFPERANVGYETLLYDCLLGDETLFQRA
DSIESTWQAAEGVLHPRDGAAIPVQAYPAGSEGPAEAAALIERDGRAWRPLAARQAGAEAQAKAASHSASKPKPKPKPQA
DAGKP
>Mature_564_residues
PLNDATRAPSDQARQPAGAKVPAPSRGAPAAPAGRHPAPPCTLVIFGAGGDLTSRLLMPALYNLAADGLLDEGTKIIGVN
HGERETEAWRDDLHSALQKLAADKASTFHAGKLDEHAWRWVAQRLQYLAGDFEDEGTYRRLAQQLGAGGPGAAHGSVAFY
LAVSGRFFKPIVERLGKAGLLEQAGDGGPFRRVVIEKPFGTDLASARDLNRHLLGFMKESQIYRIDHFLGKETVQSILAV
RFANALFEPIWRREYIDSVQIAASEVIGVERRGSFYEQTGAFRDMVPNHLFQLLGMVAMEPPNSFDARAVRDKKAEVFDA
LKPLAPRDVVFGQYAAGPGGAAYRDEPDVAPDSTTETYAAARVQIDNWRWAGVPFYLRTGKRLAERRTEIAVQLKPVPFR
LFRDTPTDALTPNVLTLRIDPSHGTSFDFNVKTPGPVMRVGAVRSSFDYDAFFPERANVGYETLLYDCLLGDETLFQRAD
SIESTWQAAEGVLHPRDGAAIPVQAYPAGSEGPAEAAALIERDGRAWRPLAARQAGAEAQAKAASHSASKPKPKPKPQAD
AGKP

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=498, Percent_Identity=33.5341365461847, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI109389365, Length=498, Percent_Identity=33.5341365461847, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI52145310, Length=498, Percent_Identity=30.3212851405622, Blast_Score=160, Evalue=4e-39,
Organism=Escherichia coli, GI1788158, Length=506, Percent_Identity=36.9565217391304, Blast_Score=315, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI17538218, Length=495, Percent_Identity=34.1414141414141, Blast_Score=280, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6324088, Length=485, Percent_Identity=35.0515463917526, Blast_Score=270, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24643350, Length=496, Percent_Identity=33.4677419354839, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24643352, Length=496, Percent_Identity=33.4677419354839, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI221513548, Length=550, Percent_Identity=26.3636363636364, Blast_Score=184, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 61454; Mature: 61323

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNDATRAPSDQARQPAGAKVPAPSRGAPAAPAGRHPAPPCTLVIFGAGGDLTSRLLMP
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
ALYNLAADGLLDEGTKIIGVNHGERETEAWRDDLHSALQKLAADKASTFHAGKLDEHAWR
HHHHHHHCCHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
WVAQRLQYLAGDFEDEGTYRRLAQQLGAGGPGAAHGSVAFYLAVSGRFFKPIVERLGKAG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCC
LLEQAGDGGPFRRVVIEKPFGTDLASARDLNRHLLGFMKESQIYRIDHFLGKETVQSILA
CHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEHHHHHHCHHHHHHHHH
VRFANALFEPIWRREYIDSVQIAASEVIGVERRGSFYEQTGAFRDMVPNHLFQLLGMVAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHC
EPPNSFDARAVRDKKAEVFDALKPLAPRDVVFGQYAAGPGGAAYRDEPDVAPDSTTETYA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHE
AARVQIDNWRWAGVPFYLRTGKRLAERRTEIAVQLKPVPFRLFRDTPTDALTPNVLTLRI
EEEEEECCEEECCCCCEEHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCEEEEEE
DPSHGTSFDFNVKTPGPVMRVGAVRSSFDYDAFFPERANVGYETLLYDCLLGDETLFQRA
ECCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
DSIESTWQAAEGVLHPRDGAAIPVQAYPAGSEGPAEAAALIERDGRAWRPLAARQAGAEA
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCHH
QAKAASHSASKPKPKPKPQADAGKP
HHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLNDATRAPSDQARQPAGAKVPAPSRGAPAAPAGRHPAPPCTLVIFGAGGDLTSRLLMP
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
ALYNLAADGLLDEGTKIIGVNHGERETEAWRDDLHSALQKLAADKASTFHAGKLDEHAWR
HHHHHHHCCHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
WVAQRLQYLAGDFEDEGTYRRLAQQLGAGGPGAAHGSVAFYLAVSGRFFKPIVERLGKAG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCC
LLEQAGDGGPFRRVVIEKPFGTDLASARDLNRHLLGFMKESQIYRIDHFLGKETVQSILA
CHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEHHHHHHCHHHHHHHHH
VRFANALFEPIWRREYIDSVQIAASEVIGVERRGSFYEQTGAFRDMVPNHLFQLLGMVAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHC
EPPNSFDARAVRDKKAEVFDALKPLAPRDVVFGQYAAGPGGAAYRDEPDVAPDSTTETYA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHE
AARVQIDNWRWAGVPFYLRTGKRLAERRTEIAVQLKPVPFRLFRDTPTDALTPNVLTLRI
EEEEEECCEEECCCCCEEHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCEEEEEE
DPSHGTSFDFNVKTPGPVMRVGAVRSSFDYDAFFPERANVGYETLLYDCLLGDETLFQRA
ECCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
DSIESTWQAAEGVLHPRDGAAIPVQAYPAGSEGPAEAAALIERDGRAWRPLAARQAGAEA
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCHH
QAKAASHSASKPKPKPKPQADAGKP
HHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]