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The map label for this gene is cobF [H]

Identifier: 238024586

GI number: 238024586

Start: 1532033

End: 1532806

Strand: Reverse

Name: cobF [H]

Synonym: bglu_2g11970

Alternate gene names: 238024586

Gene position: 1532806-1532033 (Counterclockwise)

Preceding gene: 238024587

Following gene: 238024584

Centisome position: 54.21

GC content: 70.41

Gene sequence:

>774_bases
GTGAAACGCATTCTCGTGATCGGCATCGGTGCCGGCAATCCCGACTACCTGACCGTGCAGGCCATCAAGGCGCTGAATCG
CGCCGACGTGTTCTTCGTGATGGACAAGGGCGCGGCCAAGAGCAAGCTGATCGCGCTGCGCCGCGAGATCGTCGAGCGCT
ACGCCACCGAGCGCCCCTACCGCATGGTCGAGGCCACCAGCCCCGAGCGCGGCCCCGACGGCGCCAGCTACGTGGGCGCG
GTCGAGACGCTCAACCGCGACAAGCAGGCCGTGTTCGAGCGGCTGATCGCCGAGGAACTGCGCGACGGCGAATGCGGCGC
GTTCCTGGTGTGGGGCGATCCCGCGCTCTACGACAGCACGCTGCGCATCCTCGACGCGATCCTCGCCGACGGCCGGCTTC
GCTTCGACTACGAGGTGATCCCGGGCATCAGCAGCGTGCAGGCGCTCGCCGCGCGGCATCGCGTGCCGCTCAACGCGATC
GGCCGCGCGTTCGAGGTCACCAACGGCCGCGGGCTCGCCGAGGCCGGTTTCCCGCCGCGGGCGGACAGCGTGGTGGTGAT
GCTCGACGCGCAGAACGCGTTCACGCGCCTGGACGGCGAGGCCCTCGAGATCTTCTGGGGCGCCTACGTCGGCACGCCCG
ACGAGATCCTCGTGTCCGGCCCGCTGGGCGAGGTGCGCGACGAGATCGTGCGGGTCCGCGCCGAGGCGCGCGAGCGGCAC
GGCTGGATCATGGATACCTATCTGCTCAGGAAGCGCGCGCGCAGCGGCGAGTGA

Upstream 100 bases:

>100_bases
CACGGCGGGGCGGGCGGCACGGGCCGCGGCGGGTCCGTGCGGGCGGCCGGCGAAAGCGGGTAGACTCCGCAGCTTCGTCG
TCCGCGATAGGGAGCAACTC

Downstream 100 bases:

>100_bases
GCCGCCGCCCGGCCCTCAAGCGAACCAGCGGTTGGTGCGCGCCCAGCGCGCGAACAGCTTCGGCCACGAGGCCGGCTCGC
TGTCCGGCACGCCGAGCGAC

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKRILVIGIGAGNPDYLTVQAIKALNRADVFFVMDKGAAKSKLIALRREIVERYATERPYRMVEATSPERGPDGASYVGA
VETLNRDKQAVFERLIAEELRDGECGAFLVWGDPALYDSTLRILDAILADGRLRFDYEVIPGISSVQALAARHRVPLNAI
GRAFEVTNGRGLAEAGFPPRADSVVVMLDAQNAFTRLDGEALEIFWGAYVGTPDEILVSGPLGEVRDEIVRVRAEARERH
GWIMDTYLLRKRARSGE

Sequences:

>Translated_257_residues
MKRILVIGIGAGNPDYLTVQAIKALNRADVFFVMDKGAAKSKLIALRREIVERYATERPYRMVEATSPERGPDGASYVGA
VETLNRDKQAVFERLIAEELRDGECGAFLVWGDPALYDSTLRILDAILADGRLRFDYEVIPGISSVQALAARHRVPLNAI
GRAFEVTNGRGLAEAGFPPRADSVVVMLDAQNAFTRLDGEALEIFWGAYVGTPDEILVSGPLGEVRDEIVRVRAEARERH
GWIMDTYLLRKRARSGE
>Mature_257_residues
MKRILVIGIGAGNPDYLTVQAIKALNRADVFFVMDKGAAKSKLIALRREIVERYATERPYRMVEATSPERGPDGASYVGA
VETLNRDKQAVFERLIAEELRDGECGAFLVWGDPALYDSTLRILDAILADGRLRFDYEVIPGISSVQALAARHRVPLNAI
GRAFEVTNGRGLAEAGFPPRADSVVVMLDAQNAFTRLDGEALEIFWGAYVGTPDEILVSGPLGEVRDEIVRVRAEARERH
GWIMDTYLLRKRARSGE

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 28432; Mature: 28432

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILVIGIGAGNPDYLTVQAIKALNRADVFFVMDKGAAKSKLIALRREIVERYATERPY
CCEEEEEEECCCCCCEEHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCE
RMVEATSPERGPDGASYVGAVETLNRDKQAVFERLIAEELRDGECGAFLVWGDPALYDST
EEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHH
LRILDAILADGRLRFDYEVIPGISSVQALAARHRVPLNAIGRAFEVTNGRGLAEAGFPPR
HHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHCCCCHHHHCCEEEECCCCCCCCCCCCCC
ADSVVVMLDAQNAFTRLDGEALEIFWGAYVGTPDEILVSGPLGEVRDEIVRVRAEARERH
CCCEEEEEECCCHHHHCCCCCEEEEEEHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHC
GWIMDTYLLRKRARSGE
CCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRILVIGIGAGNPDYLTVQAIKALNRADVFFVMDKGAAKSKLIALRREIVERYATERPY
CCEEEEEEECCCCCCEEHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCE
RMVEATSPERGPDGASYVGAVETLNRDKQAVFERLIAEELRDGECGAFLVWGDPALYDST
EEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHH
LRILDAILADGRLRFDYEVIPGISSVQALAARHRVPLNAIGRAFEVTNGRGLAEAGFPPR
HHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHCCCCHHHHCCEEEECCCCCCCCCCCCCC
ADSVVVMLDAQNAFTRLDGEALEIFWGAYVGTPDEILVSGPLGEVRDEIVRVRAEARERH
CCCEEEEEECCCHHHHCCCCCEEEEEEHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHC
GWIMDTYLLRKRARSGE
CCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]