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The map label for this gene is tcp [H]

Identifier: 238024577

GI number: 238024577

Start: 1510626

End: 1512191

Strand: Reverse

Name: tcp [H]

Synonym: bglu_2g11880

Alternate gene names: 238024577

Gene position: 1512191-1510626 (Counterclockwise)

Preceding gene: 238024578

Following gene: 238024576

Centisome position: 53.48

GC content: 64.3

Gene sequence:

>1566_bases
ATGCGCACACTCAGCTTCAAGCAGAAACTCTGGCTGCCCCTCATGGCAAGTCTCGCGGCACTGCTCGTCATTTCCACGTC
CGCTGCCTACCTGTCGTACGAGACGCGCCTGAAAGAGCGCAAAATCGACCTCGTCAACAGCGCGCAGATCGGCTTGAGCA
TCGTGAAGGAATATGCTGAGCTCGCACGTAACGGCAAGCTCAGCGAAGACGACGCTCGCAAACAGGCGCTCGAGCGGCTG
CGCGGCGTGCGCTACGGCAGCGACGGCTACTTCCTGGTACTCGACGGGAACGCGCGGATGGTCATGCATCCCATGAAGCC
GAAAACCGAAGGCACCGATCTGTCCGCCGTGGCGGACGTAGACGGCCGGCACCACTACGCCACGTTCGTGCAGGTCGCAA
CGGGGCCGCAGGGCGCAGGCTTCGTCGACTACGTGTTTCCGCGCCCCGGCGTGACGCCTGCCAAGGCCGTGCCGAAGCTC
GGGTACGTGCTGCGCTACGCGCCGTGGAACTGGATTCTTTCCACGGGCGCGTACCTGGACGACATCAAGGACGCCTTCTA
TCTCTCGCTCTATGTGACGGTCGGGCTGTTCGTCTCCGTCGCCGCGATGCTCGGACTGCTGGTGGCGCTCATCAATCGCA
GCATCGAACGCACCATAGGCGGCGATCCGGTTCATGCCATGCACGTGACGCACGAGATCGCCGCCGGCAACCTGGCGGTG
ACAGTCGTCACGCGTAGCGGCGACAAGGCGAGCCTCATGCAAGGCATTCACGTCATGCGCGAGGCGCTGGACGGCATGGT
GAAGCACATTCGGCGCACAGCGGGCGCGATCACCACGGCTACCAGCGAAATTGCGAGCGGCAACCTGGACCTTTCCGCGC
GCACGGAGGAACAGGCGGCATCGCTCCAGGAGACGGCGGCGAGTCTCACGCAACTGACGCAGACCGTGAAGCAAAACGCC
GACAACGCACGCGAGGCGAACCAGCTGGCGGCGCGCGCCACGCACATCACTGGCGAGGGCAACTCCGCGGTGCACCACAT
GGTCGACACGATCGAGCGGATCAACAGCAGTTCGGCGAAGATCTCCGAGATCACTAACGTGATCGAGGGAATCGCGTTTC
AGACCAACATACTGGCGCTCAATGCGGCGGTGGAAGCCGCGCGCGCGGGCGAGGACGGGCGCGGCTTCGCGGTGGTGGCA
GGGGAGGTGCGCAGCCTCGCCCAGCGATCGGCCTCGGCCGCCAAGGAGATCAAGGAACTGATCGGTTCGTCGGTGGCGAT
GATTCGCGACGGCGCGACCCAGGCCACCGAAGTGGGCGCGACCATGGACGAGATCAAGTCTTCCATCAAGCGGGTTTCGG
ATATCGTCGGAGAAATCGCCGCGGCATCCGAAGAACAAAGCCGCGGCATCGAGCAGGTGAGTCTTGCCGTTACGCAGATG
GACGAGGTCACGCAGCGCAATGCTGCCCTCGTCGAACAGGCCGCGGCCGCGGCGCAGTCGCTCGAAGAGCAGGCCACGTC
GCTGAAGGACGCAGTCGCGGTGTTCCATGTGGAAGACAGGGGCTGA

Upstream 100 bases:

>100_bases
CGTAATACAAAGAAGCGTTTGGCTCGGTCGCTTGCATGCGGCGCAAGCCAGCGCAAGTGGCGGTCCGGCCGTTCATGATG
CACACTCTCGCGAAAACATG

Downstream 100 bases:

>100_bases
GGGCGTGGCGACGCATGTGGCGGGCTATTGCCTGGCTAACGACGTGTCGGAGCGCGGCTGGCAGACGAAGCGCAACGGCC
AGTGGGGAAGGGGAAGAGCT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MRTLSFKQKLWLPLMASLAALLVISTSAAYLSYETRLKERKIDLVNSAQIGLSIVKEYAELARNGKLSEDDARKQALERL
RGVRYGSDGYFLVLDGNARMVMHPMKPKTEGTDLSAVADVDGRHHYATFVQVATGPQGAGFVDYVFPRPGVTPAKAVPKL
GYVLRYAPWNWILSTGAYLDDIKDAFYLSLYVTVGLFVSVAAMLGLLVALINRSIERTIGGDPVHAMHVTHEIAAGNLAV
TVVTRSGDKASLMQGIHVMREALDGMVKHIRRTAGAITTATSEIASGNLDLSARTEEQAASLQETAASLTQLTQTVKQNA
DNAREANQLAARATHITGEGNSAVHHMVDTIERINSSSAKISEITNVIEGIAFQTNILALNAAVEAARAGEDGRGFAVVA
GEVRSLAQRSASAAKEIKELIGSSVAMIRDGATQATEVGATMDEIKSSIKRVSDIVGEIAAASEEQSRGIEQVSLAVTQM
DEVTQRNAALVEQAAAAAQSLEEQATSLKDAVAVFHVEDRG

Sequences:

>Translated_521_residues
MRTLSFKQKLWLPLMASLAALLVISTSAAYLSYETRLKERKIDLVNSAQIGLSIVKEYAELARNGKLSEDDARKQALERL
RGVRYGSDGYFLVLDGNARMVMHPMKPKTEGTDLSAVADVDGRHHYATFVQVATGPQGAGFVDYVFPRPGVTPAKAVPKL
GYVLRYAPWNWILSTGAYLDDIKDAFYLSLYVTVGLFVSVAAMLGLLVALINRSIERTIGGDPVHAMHVTHEIAAGNLAV
TVVTRSGDKASLMQGIHVMREALDGMVKHIRRTAGAITTATSEIASGNLDLSARTEEQAASLQETAASLTQLTQTVKQNA
DNAREANQLAARATHITGEGNSAVHHMVDTIERINSSSAKISEITNVIEGIAFQTNILALNAAVEAARAGEDGRGFAVVA
GEVRSLAQRSASAAKEIKELIGSSVAMIRDGATQATEVGATMDEIKSSIKRVSDIVGEIAAASEEQSRGIEQVSLAVTQM
DEVTQRNAALVEQAAAAAQSLEEQATSLKDAVAVFHVEDRG
>Mature_521_residues
MRTLSFKQKLWLPLMASLAALLVISTSAAYLSYETRLKERKIDLVNSAQIGLSIVKEYAELARNGKLSEDDARKQALERL
RGVRYGSDGYFLVLDGNARMVMHPMKPKTEGTDLSAVADVDGRHHYATFVQVATGPQGAGFVDYVFPRPGVTPAKAVPKL
GYVLRYAPWNWILSTGAYLDDIKDAFYLSLYVTVGLFVSVAAMLGLLVALINRSIERTIGGDPVHAMHVTHEIAAGNLAV
TVVTRSGDKASLMQGIHVMREALDGMVKHIRRTAGAITTATSEIASGNLDLSARTEEQAASLQETAASLTQLTQTVKQNA
DNAREANQLAARATHITGEGNSAVHHMVDTIERINSSSAKISEITNVIEGIAFQTNILALNAAVEAARAGEDGRGFAVVA
GEVRSLAQRSASAAKEIKELIGSSVAMIRDGATQATEVGATMDEIKSSIKRVSDIVGEIAAASEEQSRGIEQVSLAVTQM
DEVTQRNAALVEQAAAAAQSLEEQATSLKDAVAVFHVEDRG

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=288, Percent_Identity=55.9027777777778, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=57.1428571428571, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI2367378, Length=394, Percent_Identity=50, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=52, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1789453, Length=335, Percent_Identity=33.7313432835821, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55684; Mature: 55684

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLSFKQKLWLPLMASLAALLVISTSAAYLSYETRLKERKIDLVNSAQIGLSIVKEYAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LARNGKLSEDDARKQALERLRGVRYGSDGYFLVLDGNARMVMHPMKPKTEGTDLSAVADV
HHHCCCCCCHHHHHHHHHHHHCCEECCCCEEEEECCCCEEEEECCCCCCCCCCCCEEECC
DGRHHYATFVQVATGPQGAGFVDYVFPRPGVTPAKAVPKLGYVLRYAPWNWILSTGAYLD
CCCCEEEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHEEECCHHHHHHCCCHHH
DIKDAFYLSLYVTVGLFVSVAAMLGLLVALINRSIERTIGGDPVHAMHVTHEIAAGNLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEE
TVVTRSGDKASLMQGIHVMREALDGMVKHIRRTAGAITTATSEIASGNLDLSARTEEQAA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
SLQETAASLTQLTQTVKQNADNAREANQLAARATHITGEGNSAVHHMVDTIERINSSSAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHH
ISEITNVIEGIAFQTNILALNAAVEAARAGEDGRGFAVVAGEVRSLAQRSASAAKEIKEL
HHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
IGSSVAMIRDGATQATEVGATMDEIKSSIKRVSDIVGEIAAASEEQSRGIEQVSLAVTQM
HCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHH
DEVTQRNAALVEQAAAAAQSLEEQATSLKDAVAVFHVEDRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
>Mature Secondary Structure
MRTLSFKQKLWLPLMASLAALLVISTSAAYLSYETRLKERKIDLVNSAQIGLSIVKEYAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LARNGKLSEDDARKQALERLRGVRYGSDGYFLVLDGNARMVMHPMKPKTEGTDLSAVADV
HHHCCCCCCHHHHHHHHHHHHCCEECCCCEEEEECCCCEEEEECCCCCCCCCCCCEEECC
DGRHHYATFVQVATGPQGAGFVDYVFPRPGVTPAKAVPKLGYVLRYAPWNWILSTGAYLD
CCCCEEEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHEEECCHHHHHHCCCHHH
DIKDAFYLSLYVTVGLFVSVAAMLGLLVALINRSIERTIGGDPVHAMHVTHEIAAGNLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEE
TVVTRSGDKASLMQGIHVMREALDGMVKHIRRTAGAITTATSEIASGNLDLSARTEEQAA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
SLQETAASLTQLTQTVKQNADNAREANQLAARATHITGEGNSAVHHMVDTIERINSSSAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHH
ISEITNVIEGIAFQTNILALNAAVEAARAGEDGRGFAVVAGEVRSLAQRSASAAKEIKEL
HHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
IGSSVAMIRDGATQATEVGATMDEIKSSIKRVSDIVGEIAAASEEQSRGIEQVSLAVTQM
HCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHH
DEVTQRNAALVEQAAAAAQSLEEQATSLKDAVAVFHVEDRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]