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The map label for this gene is tcp [H]

Identifier: 238024571

GI number: 238024571

Start: 1501165

End: 1502748

Strand: Reverse

Name: tcp [H]

Synonym: bglu_2g11800

Alternate gene names: 238024571

Gene position: 1502748-1501165 (Counterclockwise)

Preceding gene: 238024572

Following gene: 238024570

Centisome position: 53.15

GC content: 64.14

Gene sequence:

>1584_bases
ATGGACTGGAAAAATTGGAAGATTGGAGTGCGCCTGGGCACCGGCTTTTTTATGGTGCTGGCACTCATGGTCACGCTGAT
TGCCGTGGTGGAAATACGCTTGGCGGGGATCGAGCAGATAAACGATGGAATCATCAAGCGGGATTGGATTAAGGCAAAGG
CGGCGCATAACATCAATGCGCTGACGCGCGCCAATGCGGCGCTGACGATGCAGCTGTTCATTACCACCGACCCGGCCAGG
CTCACCGGGATTCGCCAGGGCATCAACGCCAACAAGGCCGCCATCACCGCCTTTCTCGATACGCTCGACCGGCAGTCCGA
CAATACCGACAGCCAGGGCTTGCTCGCGAGAGTGAGAGCGACGCGCGAGGCCTACGTGCGCTCGTTCAGTCAGGTGTCGA
ATCTGCTGGCAGCCGGCCGGCATGACGAGGCAGTGGCCCTGATGAACGGCGAAACCCTAGGAGCCCTGAATGAACTGCAG
CAGTCGGTGGCCGCGCTGACTGAGCTACAGGACGCCCGGGTCGCTCAGGCGGGCGCCCGATCCCGGGAGAATATCTCCGA
GGTGCACGTCCTGATGCTCACGCTCGGCGCGGTCGCGCTGTTGATCGGGATCGGCTTCGCATACATGATCCTGCGCTCGA
TCACCCGCCCGCTGCACGAGGCGCTACGGATCGCCCAGACGATCGCGGCCGGAGATCTGACCGCTCATATTGATCCGCGA
TACCGTGACGAGACGGGCGAGCTGCTGCTTGCGTTGCGCGACATGAACCACAACCTGAAGAACGTGGTCGGAGAAGTGCG
GGCCAGCGCGGACACCATTGCCATCGCGTCGAGCCAGATTGCGTCGGGCAACGAGGATTTGTCCGCGCGCACCGAGGAGC
AGGCCGCTTCGCTCGAGGAAACTGCCGCGAGCATGGAGGAGCTGACCTCCATCGTCAAGCAGAACGCGGAGCATGCGAGG
CAGGCAAGCGAGTTGGCGGTGCGTGCGTCCGAGATCGCGCATCGCGGCAATGAGGTGGTGGGGCAGGTGGTGGGGGCCAT
GACCGAGATCAGCGAGAGGTCGTCGAAGATCGCCGACATCATCAGCATCATCGAAGGCATTGCCTTCCAGACCAATATCC
TTGCGCTAAACGCCGCCGTGGAGGCGGCCCGCGCCGGCGAGCAGGGGCGCAGCTTCGCGGTGGTTGCCGGCGAGGTGCGC
TCTCTTGCGCAGCGCTCGTCCGATGCTGCGCGGGAAATCAAGGCGCTCATCTCGACCTCCGTGCAGAAAATCGAAGACGG
CTCGGAACGAGCCGGCGACGCGGGCCGCACGATGGCCGAAGTGACGCAGGCGGTGAGGCGCGTGACCGACATCATGGGCG
AGATCGCGGCCGCCTCTGGCGAGCAGAGCCGCGGTATCGAGCAGGTCAACCGGGCGGTCGAGCAGATGGACGAGGTGACC
CAGCAAAACGCGGCGCTGGTCGAACAGGCGGCCGCTGCCTCGAAGTCGCTCGAGAACGAGGGCCGCTTGCTCACGGCGGC
AATGACCTTCTTCCGTCTCGACGAGGCGCCGCACCGAGGATTGCCGGCGCTGCGCGAAAGCTGA

Upstream 100 bases:

>100_bases
CGGGAAGACGCCTATCCCCTGAAGAATGGATGGCAGCGAGGCCGGGCGGCGCGGATGGGACGTTGTAACGGTATTGCAAC
ACCGACAGGGTGGTAACGGC

Downstream 100 bases:

>100_bases
GCGGCGCGCTTGATGGTGCCGGGCCGTCCTGGACCCGCCGCCAGGCAGTGCACGGCTCAGCGGCGCCTTGCAAGCCGGCA
AGCCGGCAAGCCGGCGACCG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MDWKNWKIGVRLGTGFFMVLALMVTLIAVVEIRLAGIEQINDGIIKRDWIKAKAAHNINALTRANAALTMQLFITTDPAR
LTGIRQGINANKAAITAFLDTLDRQSDNTDSQGLLARVRATREAYVRSFSQVSNLLAAGRHDEAVALMNGETLGALNELQ
QSVAALTELQDARVAQAGARSRENISEVHVLMLTLGAVALLIGIGFAYMILRSITRPLHEALRIAQTIAAGDLTAHIDPR
YRDETGELLLALRDMNHNLKNVVGEVRASADTIAIASSQIASGNEDLSARTEEQAASLEETAASMEELTSIVKQNAEHAR
QASELAVRASEIAHRGNEVVGQVVGAMTEISERSSKIADIISIIEGIAFQTNILALNAAVEAARAGEQGRSFAVVAGEVR
SLAQRSSDAAREIKALISTSVQKIEDGSERAGDAGRTMAEVTQAVRRVTDIMGEIAAASGEQSRGIEQVNRAVEQMDEVT
QQNAALVEQAAAASKSLENEGRLLTAAMTFFRLDEAPHRGLPALRES

Sequences:

>Translated_527_residues
MDWKNWKIGVRLGTGFFMVLALMVTLIAVVEIRLAGIEQINDGIIKRDWIKAKAAHNINALTRANAALTMQLFITTDPAR
LTGIRQGINANKAAITAFLDTLDRQSDNTDSQGLLARVRATREAYVRSFSQVSNLLAAGRHDEAVALMNGETLGALNELQ
QSVAALTELQDARVAQAGARSRENISEVHVLMLTLGAVALLIGIGFAYMILRSITRPLHEALRIAQTIAAGDLTAHIDPR
YRDETGELLLALRDMNHNLKNVVGEVRASADTIAIASSQIASGNEDLSARTEEQAASLEETAASMEELTSIVKQNAEHAR
QASELAVRASEIAHRGNEVVGQVVGAMTEISERSSKIADIISIIEGIAFQTNILALNAAVEAARAGEQGRSFAVVAGEVR
SLAQRSSDAAREIKALISTSVQKIEDGSERAGDAGRTMAEVTQAVRRVTDIMGEIAAASGEQSRGIEQVNRAVEQMDEVT
QQNAALVEQAAAASKSLENEGRLLTAAMTFFRLDEAPHRGLPALRES
>Mature_527_residues
MDWKNWKIGVRLGTGFFMVLALMVTLIAVVEIRLAGIEQINDGIIKRDWIKAKAAHNINALTRANAALTMQLFITTDPAR
LTGIRQGINANKAAITAFLDTLDRQSDNTDSQGLLARVRATREAYVRSFSQVSNLLAAGRHDEAVALMNGETLGALNELQ
QSVAALTELQDARVAQAGARSRENISEVHVLMLTLGAVALLIGIGFAYMILRSITRPLHEALRIAQTIAAGDLTAHIDPR
YRDETGELLLALRDMNHNLKNVVGEVRASADTIAIASSQIASGNEDLSARTEEQAASLEETAASMEELTSIVKQNAEHAR
QASELAVRASEIAHRGNEVVGQVVGAMTEISERSSKIADIISIIEGIAFQTNILALNAAVEAARAGEQGRSFAVVAGEVR
SLAQRSSDAAREIKALISTSVQKIEDGSERAGDAGRTMAEVTQAVRRVTDIMGEIAAASGEQSRGIEQVNRAVEQMDEVT
QQNAALVEQAAAASKSLENEGRLLTAAMTFFRLDEAPHRGLPALRES

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=402, Percent_Identity=51.4925373134328, Blast_Score=322, Evalue=5e-89,
Organism=Escherichia coli, GI1787690, Length=326, Percent_Identity=54.601226993865, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1788195, Length=315, Percent_Identity=55.8730158730159, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1788194, Length=339, Percent_Identity=49.5575221238938, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1789453, Length=323, Percent_Identity=36.5325077399381, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56565; Mature: 56565

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWKNWKIGVRLGTGFFMVLALMVTLIAVVEIRLAGIEQINDGIIKRDWIKAKAAHNINA
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHH
LTRANAALTMQLFITTDPARLTGIRQGINANKAAITAFLDTLDRQSDNTDSQGLLARVRA
HHHCCCEEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TREAYVRSFSQVSNLLAAGRHDEAVALMNGETLGALNELQQSVAALTELQDARVAQAGAR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRENISEVHVLMLTLGAVALLIGIGFAYMILRSITRPLHEALRIAQTIAAGDLTAHIDPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
YRDETGELLLALRDMNHNLKNVVGEVRASADTIAIASSQIASGNEDLSARTEEQAASLEE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHEEEHHHHCCCCCCHHHHHHHHHHHHHH
TAASMEELTSIVKQNAEHARQASELAVRASEIAHRGNEVVGQVVGAMTEISERSSKIADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ISIIEGIAFQTNILALNAAVEAARAGEQGRSFAVVAGEVRSLAQRSSDAAREIKALISTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHH
VQKIEDGSERAGDAGRTMAEVTQAVRRVTDIMGEIAAASGEQSRGIEQVNRAVEQMDEVT
HHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHH
QQNAALVEQAAAASKSLENEGRLLTAAMTFFRLDEAPHRGLPALRES
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHCCC
>Mature Secondary Structure
MDWKNWKIGVRLGTGFFMVLALMVTLIAVVEIRLAGIEQINDGIIKRDWIKAKAAHNINA
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHH
LTRANAALTMQLFITTDPARLTGIRQGINANKAAITAFLDTLDRQSDNTDSQGLLARVRA
HHHCCCEEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TREAYVRSFSQVSNLLAAGRHDEAVALMNGETLGALNELQQSVAALTELQDARVAQAGAR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRENISEVHVLMLTLGAVALLIGIGFAYMILRSITRPLHEALRIAQTIAAGDLTAHIDPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
YRDETGELLLALRDMNHNLKNVVGEVRASADTIAIASSQIASGNEDLSARTEEQAASLEE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHEEEHHHHCCCCCCHHHHHHHHHHHHHH
TAASMEELTSIVKQNAEHARQASELAVRASEIAHRGNEVVGQVVGAMTEISERSSKIADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ISIIEGIAFQTNILALNAAVEAARAGEQGRSFAVVAGEVRSLAQRSSDAAREIKALISTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHH
VQKIEDGSERAGDAGRTMAEVTQAVRRVTDIMGEIAAASGEQSRGIEQVNRAVEQMDEVT
HHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHH
QQNAALVEQAAAASKSLENEGRLLTAAMTFFRLDEAPHRGLPALRES
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]