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The map label for this gene is clpX [H]

Identifier: 23501986

GI number: 23501986

Start: 1083978

End: 1085252

Strand: Reverse

Name: clpX [H]

Synonym: BR1108

Alternate gene names: 23501986

Gene position: 1085252-1083978 (Counterclockwise)

Preceding gene: 23501987

Following gene: 23501984

Centisome position: 51.49

GC content: 56.39

Gene sequence:

>1275_bases
ATGAGCAAAGTCAGCAACGGCGGCGGCGATTCCAAGAATACGCTTTATTGCTCGTTCTGTGGCAAAAGCCAGCATGAAGT
GCGCAAGCTGATTGCAGGCCCGACCGTTTTCATCTGCGACGAATGCGTCGAACTCTGCATGGACATCATCCGTGAGGAAA
ACAAATCCTCCATGGTGAAGTCGCGTGAGGGAGTGCCGACGCCGCAGGAAATCATGGCCGTCCTTGACGATTACGTCATC
GGCCAGAAGGATGCCAAGCGCGTTCTGTCGGTTGCGGTTCACAATCATTACAAGCGTCTGGCGCATCAGTCCAAGAACAG
CGATATCGAACTGGCGAAGTCGAACATTCTGCTCGTCGGCCCGACGGGCTGCGGCAAGACCTATCTTGCCCAGACGCTTG
CCCGCATCATCGATGTGCCGTTCATCATGGCGGATGCGACGACGCTGACGGAAGCCGGCTATGTCGGCGAAGATGTGGAG
AACATCATCCTGAAGCTGCTTCAGGCCGCCGATTATAATGTGGAGCGCGCGCAGCGCGGCATCGTCTATATTGATGAAGT
GGACAAGATCAGCCGCAAGTCGGACAATCCATCCATTACCCGTGACGTATCGGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGATCATGGAAGGCACTGTCGCTTCCGTGCCGCCGCAGGGTGGGCGCAAGCATCCGCAGCAGGAATTCCTGCAGGTGGAT
ACGACAAACATCCTGTTTATCTGCGGTGGTGCTTTTGCGGGTCTCGACCGTATCATTTCCGCTCGCGGCGAGAAGACCTC
CATCGGCTTTGGCGCTACGGTCAAGTCCGTCGATGAGCGTCGTATCGGTGAAGTCTTCAAGGAACTGGAACCGGAAGACC
TGTTGAAATTCGGCCTGATTCCGGAATTTGTCGGTCGTCTGCCTGTCATCGCTACGCTCGAAGACCTCGACGTCGATGCT
CTGGTCCAGATTCTGACCGAGCCGAAGAATGCGCTCGTGAAGCAGTATCAGCGCCTGTTCGACATGGAAAATGTCGAACT
GGTGTTCCATGACGATGCGTTGCGCGCGATTGCCAACAAGGCTGTCGAACACAAGACGGGTGCACGCGGCCTGCGTTCGA
TCATGGAAAAGATTCTGCTCGATACCATGTTTGAACTGCCGACGCTGGAAGGCGTTCGCGAAGTTGTGATTTCGGGCGAT
GTGGTGGATGGAAGCGCCCGCCCGCTATACATCTACGCCGAGCGGCAGGACGAAAAGGGCAACGTTTCAGCCTGA

Upstream 100 bases:

>100_bases
GGCGGGAGGCGCGTTTTCCCTCCCGGACCGGGTCCGAACCGGAAGAAACGATTGATCTGGACGCCCAAGGTCCATTTCGG
TCAATTGAAAGGAAACTGCG

Downstream 100 bases:

>100_bases
ATGGCATGAAATGTCCCTGAAAAGGCCGCGAAAGCGGCCTTTTTCATGTCCTAACCTTGCGTCAGCTTTTGCTCCCACCA
GGGCGGCGGCAACAGGGGCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVI
GQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVE
NIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDA
LVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVEHKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGD
VVDGSARPLYIYAERQDEKGNVSA

Sequences:

>Translated_424_residues
MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVI
GQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVE
NIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDA
LVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVEHKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGD
VVDGSARPLYIYAERQDEKGNVSA
>Mature_423_residues
SKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIG
QKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVEN
IILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDT
TNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDAL
VQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVEHKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDV
VDGSARPLYIYAERQDEKGNVSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=336, Percent_Identity=53.5714285714286, Blast_Score=327, Evalue=1e-89,
Organism=Escherichia coli, GI1786642, Length=414, Percent_Identity=69.5652173913043, Blast_Score=586, Evalue=1e-169,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=44.3396226415094, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=328, Percent_Identity=46.3414634146341, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=321, Percent_Identity=47.0404984423676, Blast_Score=277, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=39.2307692307692, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=38.7596899224806, Blast_Score=168, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=417, Percent_Identity=37.6498800959233, Blast_Score=259, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24648291, Length=323, Percent_Identity=51.0835913312694, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24648289, Length=323, Percent_Identity=51.0835913312694, Blast_Score=317, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46637; Mature: 46506

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVK
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
SREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVG
HCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEC
PTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRG
CCCCCHHHHHHHHHHHHCCCHHEECCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCC
IVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
CEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHEEC
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLI
CCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCC
PEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANK
HHHHCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHH
AVEHKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCCC
NVSA
CCCC
>Mature Secondary Structure 
SKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVK
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
SREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVG
HCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEC
PTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRG
CCCCCHHHHHHHHHHHHCCCHHEECCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCC
IVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
CEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHEEC
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLI
CCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCC
PEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANK
HHHHCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHH
AVEHKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCCC
NVSA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA