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The map label for this gene is hupB [C]

Identifier: 23501983

GI number: 23501983

Start: 1080652

End: 1080927

Strand: Reverse

Name: hupB [C]

Synonym: BR1105

Alternate gene names: 23501983

Gene position: 1080927-1080652 (Counterclockwise)

Preceding gene: 23501984

Following gene: 23501980

Centisome position: 51.28

GC content: 59.78

Gene sequence:

>276_bases
ATGAACAAGAACGAATTAGTCGCCGCAGTAGCGGAAAAGGGCGGTTTGACGAAGGCTGATGCCGGTACGGCTGTTGACGT
AGTGCTTGCTTCTGTGACCGCTGCCCTCAAGGCTGGTGAAGAAGTCCGTCTGCCTGGCTTCGGCGTTTTCTCCGTTTCGC
ATCGCGCCGCTTCGACCGGTCGCAACCCGTCGACCGGCAAGGAAGTTGCTATTCCCGCCCGCAACGTGCCGAAGTTCTCG
GCCGGCAAGGGCCTGAAGGACGCCGTTAACGGCTAA

Upstream 100 bases:

>100_bases
TTTTTAGTGTTGACAGGCTTGGTTTACGGCTCTTTTCGAATAAACTCCGCCCCATCCGGTCGCGTTATCCGTTCCGGTTT
AGAAAGAAAGGAAAATGCCT

Downstream 100 bases:

>100_bases
TCATGATCTGGAGAGTGAAAGCTCTTCAAACGGGTCGTGACGATAAATTTCCAGCCATCGCGACACGATCGCGAATGGCT
GTCGAGAAGGGCCCGGTTCA

Product: DNA-binding protein HU

Products: NA

Alternate protein names: HU-like protein; Px [H]

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MNKNELVAAVAEKGGLTKADAGTAVDVVLASVTAALKAGEEVRLPGFGVFSVSHRAASTGRNPSTGKEVAIPARNVPKFS
AGKGLKDAVNG

Sequences:

>Translated_91_residues
MNKNELVAAVAEKGGLTKADAGTAVDVVLASVTAALKAGEEVRLPGFGVFSVSHRAASTGRNPSTGKEVAIPARNVPKFS
AGKGLKDAVNG
>Mature_91_residues
MNKNELVAAVAEKGGLTKADAGTAVDVVLASVTAALKAGEEVRLPGFGVFSVSHRAASTGRNPSTGKEVAIPARNVPKFS
AGKGLKDAVNG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds to nod promoters and induces DNA binding [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=56.6666666666667, Blast_Score=102, Evalue=3e-24,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=55.0561797752809, Blast_Score=102, Evalue=5e-24,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=38.2022471910112, Blast_Score=69, Evalue=6e-14,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=37.3626373626374, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9102; Mature: 9102

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNELVAAVAEKGGLTKADAGTAVDVVLASVTAALKAGEEVRLPGFGVFSVSHRAASTG
CCCCCEEHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCEEECCCCHHCCC
RNPSTGKEVAIPARNVPKFSAGKGLKDAVNG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKNELVAAVAEKGGLTKADAGTAVDVVLASVTAALKAGEEVRLPGFGVFSVSHRAASTG
CCCCCEEHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCEEECCCCHHCCC
RNPSTGKEVAIPARNVPKFSAGKGLKDAVNG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 4038648; 9685414 [H]