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The map label for this gene is cat1 [H]

Identifier: 23501936

GI number: 23501936

Start: 1027268

End: 1028758

Strand: Reverse

Name: cat1 [H]

Synonym: BR1058

Alternate gene names: 23501936

Gene position: 1028758-1027268 (Counterclockwise)

Preceding gene: 23501937

Following gene: 23501935

Centisome position: 48.81

GC content: 55.33

Gene sequence:

>1491_bases
ATGTTGGAAGCACGTATCCGTAACAGTTCACTGCGAAACAAGGTTATCACTGCGGAGCAAGCGGCAAGCTTTATCAAGGA
TGGCATGATTGTTGGCATGAGCGGCTTTACGCGCGCGGGCGATGCCAAGGCCGTTCCGGTCGCCATGGCCGCGCGGGCGG
CAACCGATCCATTCCAGATCACCCTGATTACAGGGGCCTCCCTCGGACATGACGTCGATAAACTGTTGACCGAAGCGCAT
ATTCTTTCTCGCCGTATGCCGTTTCAGGCCGACCGCACATTGCGCAGCGCGATCAACCGCGGCGAAGTCATGTTTATCGA
CCAGCATCTTTCCGAAACAGTCGAGCAACTTCGTTCCAACCAGATCGGCCCCATCGACTGTGCCGTGGTAGAGGCATTGG
CGATTACCGAAAGCGGCGGAATCATCCCGACGACTTCGGTCGGCAATTCGGCCAGCCTCGCCATTCTTGCCGAAAAGGTT
ATCGTCGAGGTCAATCTGAACCAGCCCATGGCGCTGGAAGGCCTGCACGATATTTATATACCGACGAAGCGCCCTTCCCG
CGATCCTATCCCGATCATGGCTTGCGATAGCCGGATCGGACTGCCCTATATTCCCATCGCGCCGGAAAAAATCGCCGGTA
TCGTCATCACGCAGGAAAATGACAGTGCGTCACCTGTCGAGCCCGCAGATCACGAAACGGTTGCGATTGCCGGGCATCTG
ATCGAATTCTTCAAGGGGGAAGTCGTAAAGGGTCGTCTGGATCTGGCGCTTAATCCATTGCAGGCGGGCATCGGCACCAT
TGCCAATGCGGTTTTGACCGGCTTTGCAGATAGTCCTTTCCACAATCTGCGCATGTATAGCGAGGTATTGCAGGATAGCA
CGTTCGATCTGTTCGATGCGGGCAAGCTGGATTTTGCCTCCGGCTCATCGATCACTCTCAGCCCCGCTTGCGGCGAGCGC
GTTTTCAATAATATAGACCGCTATCGTGACAGGCTTGTCCTGCGCCCGCAGGAAATCAGCAACCATCCGGAAGTCATCCG
CCGTCTTGGTATTATCGGCATCAATACCGCACTCGAATTCGATATCTACGGCAACGTCAACTCAACCCATGTTGATGGAA
CCAATATGATGAACGGCATTGGCGGTTCCGGCGATTTTGCGCGCAACGCCTATATTTCGATCTTCGTCAGCAAGTCGGAA
GCCAAGAATGGCGCGATCTCCTCGGTCGTGCCCATGGTAACACATGTGGACCACACGGAACATGACGTGGATATCCTCGT
GACGGAACAGGGACTTGCCGATTTGCGCGGGCTTGCACCACGCGAGCGAGCGCCCGTTATCATTGAAAATTGCGCACATC
CCGATTACCGGGACCAGCTCATGGATTATTACGAGCGAGCCTGCAAACGCGGCGGCCACACGCCTCATCTTCTGGAAGAG
GCATTCAGTTGGCACCTGCGCCGTCAGGAAAATGGCAGTATGCGCAAATAA

Upstream 100 bases:

>100_bases
GGGGTATTACCCTGTCTGTGGGGTACGGGCGGATAAATTGATATTCGTTCGGATTATACCATTTCCGGCTTAGCGCCGGT
CGGGAAAGAAGGTAGATTAT

Downstream 100 bases:

>100_bases
CCCACAATTCCCCTGCCCCGGTATGCAATATATCGGGGCAGATTTATTTTCAGCCTTCGCCATTCTAGCTTTCAAAGCGG
AATTTTATTTTGTTCCGCGC

Product: acetyl-CoA hydrolase/transferase family protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MLEARIRNSSLRNKVITAEQAASFIKDGMIVGMSGFTRAGDAKAVPVAMAARAATDPFQITLITGASLGHDVDKLLTEAH
ILSRRMPFQADRTLRSAINRGEVMFIDQHLSETVEQLRSNQIGPIDCAVVEALAITESGGIIPTTSVGNSASLAILAEKV
IVEVNLNQPMALEGLHDIYIPTKRPSRDPIPIMACDSRIGLPYIPIAPEKIAGIVITQENDSASPVEPADHETVAIAGHL
IEFFKGEVVKGRLDLALNPLQAGIGTIANAVLTGFADSPFHNLRMYSEVLQDSTFDLFDAGKLDFASGSSITLSPACGER
VFNNIDRYRDRLVLRPQEISNHPEVIRRLGIIGINTALEFDIYGNVNSTHVDGTNMMNGIGGSGDFARNAYISIFVSKSE
AKNGAISSVVPMVTHVDHTEHDVDILVTEQGLADLRGLAPRERAPVIIENCAHPDYRDQLMDYYERACKRGGHTPHLLEE
AFSWHLRRQENGSMRK

Sequences:

>Translated_496_residues
MLEARIRNSSLRNKVITAEQAASFIKDGMIVGMSGFTRAGDAKAVPVAMAARAATDPFQITLITGASLGHDVDKLLTEAH
ILSRRMPFQADRTLRSAINRGEVMFIDQHLSETVEQLRSNQIGPIDCAVVEALAITESGGIIPTTSVGNSASLAILAEKV
IVEVNLNQPMALEGLHDIYIPTKRPSRDPIPIMACDSRIGLPYIPIAPEKIAGIVITQENDSASPVEPADHETVAIAGHL
IEFFKGEVVKGRLDLALNPLQAGIGTIANAVLTGFADSPFHNLRMYSEVLQDSTFDLFDAGKLDFASGSSITLSPACGER
VFNNIDRYRDRLVLRPQEISNHPEVIRRLGIIGINTALEFDIYGNVNSTHVDGTNMMNGIGGSGDFARNAYISIFVSKSE
AKNGAISSVVPMVTHVDHTEHDVDILVTEQGLADLRGLAPRERAPVIIENCAHPDYRDQLMDYYERACKRGGHTPHLLEE
AFSWHLRRQENGSMRK
>Mature_496_residues
MLEARIRNSSLRNKVITAEQAASFIKDGMIVGMSGFTRAGDAKAVPVAMAARAATDPFQITLITGASLGHDVDKLLTEAH
ILSRRMPFQADRTLRSAINRGEVMFIDQHLSETVEQLRSNQIGPIDCAVVEALAITESGGIIPTTSVGNSASLAILAEKV
IVEVNLNQPMALEGLHDIYIPTKRPSRDPIPIMACDSRIGLPYIPIAPEKIAGIVITQENDSASPVEPADHETVAIAGHL
IEFFKGEVVKGRLDLALNPLQAGIGTIANAVLTGFADSPFHNLRMYSEVLQDSTFDLFDAGKLDFASGSSITLSPACGER
VFNNIDRYRDRLVLRPQEISNHPEVIRRLGIIGINTALEFDIYGNVNSTHVDGTNMMNGIGGSGDFARNAYISIFVSKSE
AKNGAISSVVPMVTHVDHTEHDVDILVTEQGLADLRGLAPRERAPVIIENCAHPDYRDQLMDYYERACKRGGHTPHLLEE
AFSWHLRRQENGSMRK

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=485, Percent_Identity=45.5670103092784, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17538151, Length=217, Percent_Identity=29.4930875576037, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=517, Percent_Identity=43.7137330754352, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54059; Mature: 54059

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEARIRNSSLRNKVITAEQAASFIKDGMIVGMSGFTRAGDAKAVPVAMAARAATDPFQI
CCCCCCCCCHHHHHHEEHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEE
TLITGASLGHDVDKLLTEAHILSRRMPFQADRTLRSAINRGEVMFIDQHLSETVEQLRSN
EEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QIGPIDCAVVEALAITESGGIIPTTSVGNSASLAILAEKVIVEVNLNQPMALEGLHDIYI
CCCCCHHHHHHHHHEECCCCEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEC
PTKRPSRDPIPIMACDSRIGLPYIPIAPEKIAGIVITQENDSASPVEPADHETVAIAGHL
CCCCCCCCCCEEEEECCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCCCCCCEEHHHHHH
IEFFKGEVVKGRLDLALNPLQAGIGTIANAVLTGFADSPFHNLRMYSEVLQDSTFDLFDA
HHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
GKLDFASGSSITLSPACGERVFNNIDRYRDRLVLRPQEISNHPEVIRRLGIIGINTALEF
CCEEECCCCCEEECCHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVDGTNMMNGIGGSGDFARNAYISIFVSKSEAKNGAISSVVPMVTHVDHTE
EEECCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEQGLADLRGLAPRERAPVIIENCAHPDYRDQLMDYYERACKRGGHTPHLLEE
CCEEEEEECCCHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
AFSWHLRRQENGSMRK
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLEARIRNSSLRNKVITAEQAASFIKDGMIVGMSGFTRAGDAKAVPVAMAARAATDPFQI
CCCCCCCCCHHHHHHEEHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEE
TLITGASLGHDVDKLLTEAHILSRRMPFQADRTLRSAINRGEVMFIDQHLSETVEQLRSN
EEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QIGPIDCAVVEALAITESGGIIPTTSVGNSASLAILAEKVIVEVNLNQPMALEGLHDIYI
CCCCCHHHHHHHHHEECCCCEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEC
PTKRPSRDPIPIMACDSRIGLPYIPIAPEKIAGIVITQENDSASPVEPADHETVAIAGHL
CCCCCCCCCCEEEEECCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCCCCCCEEHHHHHH
IEFFKGEVVKGRLDLALNPLQAGIGTIANAVLTGFADSPFHNLRMYSEVLQDSTFDLFDA
HHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
GKLDFASGSSITLSPACGERVFNNIDRYRDRLVLRPQEISNHPEVIRRLGIIGINTALEF
CCEEECCCCCEEECCHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVDGTNMMNGIGGSGDFARNAYISIFVSKSEAKNGAISSVVPMVTHVDHTE
EEECCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEQGLADLRGLAPRERAPVIIENCAHPDYRDQLMDYYERACKRGGHTPHLLEE
CCEEEEEECCCHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
AFSWHLRRQENGSMRK
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]