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The map label for this gene is yycF [H]

Identifier: 23100907

GI number: 23100907

Start: 3589404

End: 3590105

Strand: Reverse

Name: yycF [H]

Synonym: OB3452

Alternate gene names: 23100907

Gene position: 3590105-3589404 (Counterclockwise)

Preceding gene: 23100908

Following gene: 23100906

Centisome position: 98.89

GC content: 39.03

Gene sequence:

>702_bases
ATGAGTCAAAAAATACTAGTAGTAGATGATGAGCAGCCAATTGCAGATATATTACAATTTAACTTAGAAAAAGAAGGCTA
CCAAGTTGTCGTAGCGAATGATGGAGATACAGCAATAGAATTAGCAGAAAGTGAAAAACCGAACCTAATTCTGTTAGATA
TTATGCTTCCGGGAAAAGACGGGAATGAAGTATTAAGAGAAGTAAGAAAAACACAAAACATACCTGTAATCATGCTTACA
GCAAAAGATGCAGAAATCGATAAAGTATTAGGACTGGAGCTTGGTGCGGATGATTACGTAACAAAGCCATTTAGTAATCG
AGAGCTTATTGCACGTGTTAAGGCGAATTTACGTCGTGAACAAGTACCTGATGAAACAGTGAAAACAACCAAAGACATCG
TTATTGGTGATCTTATCGTACACCCTGATGCGTATGTTGTATCGCGAAAAGGCGAAGAAATTGAGCTTACCCATCGTGAG
TTCGAGCTTCTACATTATCTGGCGCGTCATATAGGACAAGTAATGACAAGAGAACATCTATTAGAAACCGTATGGGGATA
TGATTATTTCGGTGATGTGCGTACAGTTGATGTGACTGTCCGTCGTCTTCGTGAAAAAATTGAAGAAAACCCAAGTAATC
CTTTATGGATTGTGACCCGAAGAGGTGTGGGCTATTATTTACGTAATCCTGAGCAGGAGTAG

Upstream 100 bases:

>100_bases
AAAGACAAATTATTATTCAGTGGACAAGACATTAATGTCATTTTGCGTTAAAATAGAAGAAAAGTTTGTGTAACTTTTGG
ATGAAAAGGATGTGGCTAAA

Downstream 100 bases:

>100_bases
TTGTATATGAATAAAGTAGGATTCTTTCGATCGATACAGTTAAAATTTATAATTATTTATATTTTACTCTTGATTATAGC
TGTGCAAGTGATAGGATCCT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSQKILVVDDEQPIADILQFNLEKEGYQVVVANDGDTAIELAESEKPNLILLDIMLPGKDGNEVLREVRKTQNIPVIMLT
AKDAEIDKVLGLELGADDYVTKPFSNRELIARVKANLRREQVPDETVKTTKDIVIGDLIVHPDAYVVSRKGEEIELTHRE
FELLHYLARHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEENPSNPLWIVTRRGVGYYLRNPEQE

Sequences:

>Translated_233_residues
MSQKILVVDDEQPIADILQFNLEKEGYQVVVANDGDTAIELAESEKPNLILLDIMLPGKDGNEVLREVRKTQNIPVIMLT
AKDAEIDKVLGLELGADDYVTKPFSNRELIARVKANLRREQVPDETVKTTKDIVIGDLIVHPDAYVVSRKGEEIELTHRE
FELLHYLARHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEENPSNPLWIVTRRGVGYYLRNPEQE
>Mature_232_residues
SQKILVVDDEQPIADILQFNLEKEGYQVVVANDGDTAIELAESEKPNLILLDIMLPGKDGNEVLREVRKTQNIPVIMLTA
KDAEIDKVLGLELGADDYVTKPFSNRELIARVKANLRREQVPDETVKTTKDIVIGDLIVHPDAYVVSRKGEEIELTHREF
ELLHYLARHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEENPSNPLWIVTRRGVGYYLRNPEQE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=42.5438596491228, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=41.8502202643172, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=37.7777777777778, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=39.6396396396396, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=38.7931034482759, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=38.6666666666667, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=38.3928571428571, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=38.2978723404255, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=36.4444444444444, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=36.2445414847162, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=35.6521739130435, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=34.6666666666667, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=33.9130434782609, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.390134529148, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=36.2903225806452, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.8943089430894, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=37.6237623762376, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26758; Mature: 26627

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKILVVDDEQPIADILQFNLEKEGYQVVVANDGDTAIELAESEKPNLILLDIMLPGKD
CCCEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCC
GNEVLREVRKTQNIPVIMLTAKDAEIDKVLGLELGADDYVTKPFSNRELIARVKANLRRE
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
QVPDETVKTTKDIVIGDLIVHPDAYVVSRKGEEIELTHREFELLHYLARHIGQVMTREHL
CCCCHHHHHHHHEEEEEEEECCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LETVWGYDYFGDVRTVDVTVRRLREKIEENPSNPLWIVTRRGVGYYLRNPEQE
HHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCC
>Mature Secondary Structure 
SQKILVVDDEQPIADILQFNLEKEGYQVVVANDGDTAIELAESEKPNLILLDIMLPGKD
CCEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCC
GNEVLREVRKTQNIPVIMLTAKDAEIDKVLGLELGADDYVTKPFSNRELIARVKANLRRE
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
QVPDETVKTTKDIVIGDLIVHPDAYVVSRKGEEIELTHREFELLHYLARHIGQVMTREHL
CCCCHHHHHHHHEEEEEEEECCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LETVWGYDYFGDVRTVDVTVRRLREKIEENPSNPLWIVTRRGVGYYLRNPEQE
HHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]