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The map label for this gene is yycG [H]

Identifier: 23100906

GI number: 23100906

Start: 3587559

End: 3589397

Strand: Reverse

Name: yycG [H]

Synonym: OB3451

Alternate gene names: 23100906

Gene position: 3589397-3587559 (Counterclockwise)

Preceding gene: 23100907

Following gene: 23100905

Centisome position: 98.87

GC content: 37.36

Gene sequence:

>1839_bases
ATGAATAAAGTAGGATTCTTTCGATCGATACAGTTAAAATTTATAATTATTTATATTTTACTCTTGATTATAGCTGTGCA
AGTGATAGGATCCTTCTTTACGGATCGCTTAAATGAAGAATTAACAAGAAATTTCAAGACTACGGTTGGCGAACGTGTAG
AAATGCTCAGTCATAATCTAGAGCAAGCATTTGCCAGAGATCGATCCGAGGAAAGTGGAACTATCGAGTCATTAGAGGAA
GAGATTCGACGGATTATTAACGATATAAATAGAGGAAATGCTTCGACGACCATCAATGTTGTGGATAATCAAAGTAGAGT
ACGAGGAACAAATGTATTGGATGACCAGAACCAAATTGGTCAAAAGCTTGCGCATCCAATGGTTCGTGATGCGCTTCTTT
TTAACTCTACGGATGATAGTATATTCTATGAAAAAGATACCGACAGTAGAGTTTATGTGTATGTCAAGCCAATATTAGGT
GAGGATAATATGGCTGTCGGGGCAATCTTTTATAAATCTTCCTTAGAAGAAGTGTATGGCCAAATTGAGGATATCAATAA
TATCTTCCTCCAAGGTTCTATTCTCGCTATTACGATTTCAGCTATTATTGGGATTTTGGTAGCACGTACAATCACAAAAC
CTATTATGGAGATGCGAGAACAAGCTTTAATAATGGCAAATGGAGATTTTACACAGAAAGTAAATGTATATGGTAGAGAT
GAAATCGGGCAACTAGCAGAGACGTTTAATGATCTCAATAGTAGGCTGAAGCATTCCTATGCCACCATTGAAGAAGAGCG
ACGAAAGCTCAGTTCGATACTAGCGAACATGTCGGATGGGGTCATTGCAACAGATAACGATGGCTCTGTTACATTAATGA
ACGATGCAGCTGCTAAGTTAATTGGTGAAAACCCAGAAGATTTAATAGGAGATTCTGTTATTGACGTCTTGCACTTAGAA
GGAAAAGAAATTGACCTAAGTGAATTGCATAGTAATGGTTCCATGATTATTGATTTTAGTAATGAGGATACACCATTCCT
TATTCGAGCCAATTTTTCAACAGTGGTTGATGAAGAAGAAGAAGTAACAGGATTTATTACCGTTATTAGTGATGTTACCG
AACAACAGAAAATGGAACAAGAACGTCGTGACTTTGTTTCCAATGTATCACATGAGCTGAGAACACCATTAACTACGATG
AAGAGTTATTTAGAGGCATTGTCGGATGGAGCTTGGGAAAACAAAGAAATTGCACCGCGATTTTTAGATGTGACTCAAAA
AGAGACGAACCGTATGATTCGTATGGTTAATGATTTACTTCAATTGTCCAAGATGGATTCGGATGAACTTCCTATGCATA
AACAACGAGAAGAGTTTACAAGTTATTTATACCAAGTATTAGATCGCTATGAAATGAATAAGCCAGAATCCATTCATATG
GAAAAAAATATCCCGAATACCAAAGCATATGTTTGGATGGACCGGGACAAGATTACACAAGTATTGGATAATGTCATAAC
GAATGCCATTAAGTATTCCCCAGACGGCGGGAAGATTAGGGTTAAATTAGATATTAGACGTCATTATTTATTAGTAAGCA
TACAAGACCAAGGAATGGGGATTGCTTACGATAAATTAGATAAAATATTTGAAAGGTTTTATCGTGTAGATAAAGCTAGA
AACCGAAAACTTGGAGGTACCGGTTTAGGACTAGCGATTACGAAAGAATTGGTTGAAGCACATCATGGTCAGATATGGGC
TCAGAGTAGTGAAGGGAAAGGCACAACAATTCTATTCACATTACCACTGATGAGCTCGAAGCGGGGGGATGTCAGATGA

Upstream 100 bases:

>100_bases
TCGTGAAAAAATTGAAGAAAACCCAAGTAATCCTTTATGGATTGTGACCCGAAGAGGTGTGGGCTATTATTTACGTAATC
CTGAGCAGGAGTAGTTGTAT

Downstream 100 bases:

>100_bases
AATTAGAGACTGCTAAATCATTACTTTTAGTCGTTTTAATTGGGACAAGTATGATTCTGACGTTCGGTATGTGGAATTAT
CAAGCTGACTATGACCCTTT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MNKVGFFRSIQLKFIIIYILLLIIAVQVIGSFFTDRLNEELTRNFKTTVGERVEMLSHNLEQAFARDRSEESGTIESLEE
EIRRIINDINRGNASTTINVVDNQSRVRGTNVLDDQNQIGQKLAHPMVRDALLFNSTDDSIFYEKDTDSRVYVYVKPILG
EDNMAVGAIFYKSSLEEVYGQIEDINNIFLQGSILAITISAIIGILVARTITKPIMEMREQALIMANGDFTQKVNVYGRD
EIGQLAETFNDLNSRLKHSYATIEEERRKLSSILANMSDGVIATDNDGSVTLMNDAAAKLIGENPEDLIGDSVIDVLHLE
GKEIDLSELHSNGSMIIDFSNEDTPFLIRANFSTVVDEEEEVTGFITVISDVTEQQKMEQERRDFVSNVSHELRTPLTTM
KSYLEALSDGAWENKEIAPRFLDVTQKETNRMIRMVNDLLQLSKMDSDELPMHKQREEFTSYLYQVLDRYEMNKPESIHM
EKNIPNTKAYVWMDRDKITQVLDNVITNAIKYSPDGGKIRVKLDIRRHYLLVSIQDQGMGIAYDKLDKIFERFYRVDKAR
NRKLGGTGLGLAITKELVEAHHGQIWAQSSEGKGTTILFTLPLMSSKRGDVR

Sequences:

>Translated_612_residues
MNKVGFFRSIQLKFIIIYILLLIIAVQVIGSFFTDRLNEELTRNFKTTVGERVEMLSHNLEQAFARDRSEESGTIESLEE
EIRRIINDINRGNASTTINVVDNQSRVRGTNVLDDQNQIGQKLAHPMVRDALLFNSTDDSIFYEKDTDSRVYVYVKPILG
EDNMAVGAIFYKSSLEEVYGQIEDINNIFLQGSILAITISAIIGILVARTITKPIMEMREQALIMANGDFTQKVNVYGRD
EIGQLAETFNDLNSRLKHSYATIEEERRKLSSILANMSDGVIATDNDGSVTLMNDAAAKLIGENPEDLIGDSVIDVLHLE
GKEIDLSELHSNGSMIIDFSNEDTPFLIRANFSTVVDEEEEVTGFITVISDVTEQQKMEQERRDFVSNVSHELRTPLTTM
KSYLEALSDGAWENKEIAPRFLDVTQKETNRMIRMVNDLLQLSKMDSDELPMHKQREEFTSYLYQVLDRYEMNKPESIHM
EKNIPNTKAYVWMDRDKITQVLDNVITNAIKYSPDGGKIRVKLDIRRHYLLVSIQDQGMGIAYDKLDKIFERFYRVDKAR
NRKLGGTGLGLAITKELVEAHHGQIWAQSSEGKGTTILFTLPLMSSKRGDVR
>Mature_612_residues
MNKVGFFRSIQLKFIIIYILLLIIAVQVIGSFFTDRLNEELTRNFKTTVGERVEMLSHNLEQAFARDRSEESGTIESLEE
EIRRIINDINRGNASTTINVVDNQSRVRGTNVLDDQNQIGQKLAHPMVRDALLFNSTDDSIFYEKDTDSRVYVYVKPILG
EDNMAVGAIFYKSSLEEVYGQIEDINNIFLQGSILAITISAIIGILVARTITKPIMEMREQALIMANGDFTQKVNVYGRD
EIGQLAETFNDLNSRLKHSYATIEEERRKLSSILANMSDGVIATDNDGSVTLMNDAAAKLIGENPEDLIGDSVIDVLHLE
GKEIDLSELHSNGSMIIDFSNEDTPFLIRANFSTVVDEEEEVTGFITVISDVTEQQKMEQERRDFVSNVSHELRTPLTTM
KSYLEALSDGAWENKEIAPRFLDVTQKETNRMIRMVNDLLQLSKMDSDELPMHKQREEFTSYLYQVLDRYEMNKPESIHM
EKNIPNTKAYVWMDRDKITQVLDNVITNAIKYSPDGGKIRVKLDIRRHYLLVSIQDQGMGIAYDKLDKIFERFYRVDKAR
NRKLGGTGLGLAITKELVEAHHGQIWAQSSEGKGTTILFTLPLMSSKRGDVR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=34.9344978165939, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786600, Length=340, Percent_Identity=30, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788549, Length=381, Percent_Identity=27.5590551181102, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786783, Length=259, Percent_Identity=32.4324324324324, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI48994928, Length=465, Percent_Identity=25.8064516129032, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790346, Length=243, Percent_Identity=30.4526748971193, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=303, Percent_Identity=25.4125412541254, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=31.981981981982, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789149, Length=246, Percent_Identity=26.4227642276423, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=28.3783783783784, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=25.7510729613734, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=28.6324786324786, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=29.5833333333333, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=348, Percent_Identity=22.9885057471264, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=25.7281553398058, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=265, Percent_Identity=27.9245283018868, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=22.4576271186441, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=28.755364806867, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=212, Percent_Identity=28.7735849056604, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789403, Length=213, Percent_Identity=28.169014084507, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787374, Length=234, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69628; Mature: 69628

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVGFFRSIQLKFIIIYILLLIIAVQVIGSFFTDRLNEELTRNFKTTVGERVEMLSHNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAFARDRSEESGTIESLEEEIRRIINDINRGNASTTINVVDNQSRVRGTNVLDDQNQIG
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHH
QKLAHPMVRDALLFNSTDDSIFYEKDTDSRVYVYVKPILGEDNMAVGAIFYKSSLEEVYG
HHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHH
QIEDINNIFLQGSILAITISAIIGILVARTITKPIMEMREQALIMANGDFTQKVNVYGRD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCH
EIGQLAETFNDLNSRLKHSYATIEEERRKLSSILANMSDGVIATDNDGSVTLMNDAAAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECHHHHHH
IGENPEDLIGDSVIDVLHLEGKEIDLSELHSNGSMIIDFSNEDTPFLIRANFSTVVDEEE
HCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCEEEEECCHHHCCCCH
EVTGFITVISDVTEQQKMEQERRDFVSNVSHELRTPLTTMKSYLEALSDGAWENKEIAPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHH
FLDVTQKETNRMIRMVNDLLQLSKMDSDELPMHKQREEFTSYLYQVLDRYEMNKPESIHM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
EKNIPNTKAYVWMDRDKITQVLDNVITNAIKYSPDGGKIRVKLDIRRHYLLVSIQDQGMG
CCCCCCCCEEEEECHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEEEEEEEEECCCCC
IAYDKLDKIFERFYRVDKARNRKLGGTGLGLAITKELVEAHHGQIWAQSSEGKGTTILFT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEE
LPLMSSKRGDVR
ECCCCCCCCCCC
>Mature Secondary Structure
MNKVGFFRSIQLKFIIIYILLLIIAVQVIGSFFTDRLNEELTRNFKTTVGERVEMLSHNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAFARDRSEESGTIESLEEEIRRIINDINRGNASTTINVVDNQSRVRGTNVLDDQNQIG
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHH
QKLAHPMVRDALLFNSTDDSIFYEKDTDSRVYVYVKPILGEDNMAVGAIFYKSSLEEVYG
HHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHH
QIEDINNIFLQGSILAITISAIIGILVARTITKPIMEMREQALIMANGDFTQKVNVYGRD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCH
EIGQLAETFNDLNSRLKHSYATIEEERRKLSSILANMSDGVIATDNDGSVTLMNDAAAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECHHHHHH
IGENPEDLIGDSVIDVLHLEGKEIDLSELHSNGSMIIDFSNEDTPFLIRANFSTVVDEEE
HCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCEEEEECCHHHCCCCH
EVTGFITVISDVTEQQKMEQERRDFVSNVSHELRTPLTTMKSYLEALSDGAWENKEIAPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHH
FLDVTQKETNRMIRMVNDLLQLSKMDSDELPMHKQREEFTSYLYQVLDRYEMNKPESIHM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
EKNIPNTKAYVWMDRDKITQVLDNVITNAIKYSPDGGKIRVKLDIRRHYLLVSIQDQGMG
CCCCCCCCEEEEECHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEEEEEEEEECCCCC
IAYDKLDKIFERFYRVDKARNRKLGGTGLGLAITKELVEAHHGQIWAQSSEGKGTTILFT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEE
LPLMSSKRGDVR
ECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]