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The map label for this gene is yrbE [H]

Identifier: 23100876

GI number: 23100876

Start: 3558748

End: 3559761

Strand: Reverse

Name: yrbE [H]

Synonym: OB3421

Alternate gene names: 23100876

Gene position: 3559761-3558748 (Counterclockwise)

Preceding gene: 23100877

Following gene: 23100875

Centisome position: 98.05

GC content: 35.21

Gene sequence:

>1014_bases
ATGCTTAATGTATTAGTTATCGGTTCGGGTACGATGGGGGGAACACATGCTAATGCTTATTCCAACTTACCCAATGTGAA
TCTTGTTGGAATTGTAGATGTGCAGTTGGAGAAAGCGTCGTTATTAGCTAAGGAACTAGGAACCAATTCGTATAAGACAT
ATGAAGAGGCTATAGAGGAAATCGGAGAAGTAGATATTGTATCTATATGCTTGCCTACGCCTCTTCATTTGGAATTTGTT
AAAAAAATCGCAGATACCAAGACTCATATTATTTGTGAAAAACCTTTAGCCAGAACATTAGAAGACGCTAAGGAGATAAT
AGACTATTGTAATTCCAAAGGTGTGAAGTTATTTGTAGGACATGTAGTACGCTTTTTTAAAGAATATAGTCGAGCAAAAC
AGTTAATAGAGGGTGGAAAGATTGGAAAGCCTGCGGTTGTTAATACAAGTAGAATAGGTGGTTTTCCTGATGCTTCAAAT
GACTGGTACTCAAATTATTCAAAAAGTGGTGGGTTAGTTCTAGATATGATTATTCATGATTTCGACTTCTTGAGATGGTG
TTTTGGAGAAGTTGATCATGTATATGCTAAAAGTTCAAAAGGAAGAGTTAATTCTAAGTTAGAGTACGCTTTAGTAACTT
TAAAATTCAATAATGGAGTTATCGCTCATGTTGAAGGATCTTGGGCACATCAAAAGTTTACTACTAAATTTGATATTGCA
GGAACGGAAGGAATATTAAATTATGATAGTTCGAAAGTGAGTCCAGTCTTTAAGAGTATCAAAGAGTTGGAAGGATCTCA
TACAGGAGTAGCAGTGCCTGAAAGTCCTTTAAAAGCAACTCCTTATCAGATTCAATTAGAACATTTTATAAATTGTGTTA
TTGAAGAAGAAAAACCGATTGTAACAGCAATAGATGCATATAAAGCCATGGAAATCGCTCTAGCGGCCCTTAAGTCAATT
GATACAGGAAAGGTTGTAGAAATCTCGAATAAAGAAATGGGGATTTTATTATGA

Upstream 100 bases:

>100_bases
GCTGATGTTTATATTCTTACAAAAATACTTATTAGCTGGAATTGCATTAGGTGGGGTCAGAAGATAGTCTATAAGTTTAA
TTAAATGGAGGTTTTAGAAA

Downstream 100 bases:

>100_bases
AAATAGGAATTATTAGTTTCGCACATTCTCATGCACATAGCTATGCACATGCATTGCAATCAATAGAAAACATTGAAATT
GTTGGCATATATGATGACAA

Product: NADH-dependent dyhydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLNVLVIGSGTMGGTHANAYSNLPNVNLVGIVDVQLEKASLLAKELGTNSYKTYEEAIEEIGEVDIVSICLPTPLHLEFV
KKIADTKTHIICEKPLARTLEDAKEIIDYCNSKGVKLFVGHVVRFFKEYSRAKQLIEGGKIGKPAVVNTSRIGGFPDASN
DWYSNYSKSGGLVLDMIIHDFDFLRWCFGEVDHVYAKSSKGRVNSKLEYALVTLKFNNGVIAHVEGSWAHQKFTTKFDIA
GTEGILNYDSSKVSPVFKSIKELEGSHTGVAVPESPLKATPYQIQLEHFINCVIEEEKPIVTAIDAYKAMEIALAALKSI
DTGKVVEISNKEMGILL

Sequences:

>Translated_337_residues
MLNVLVIGSGTMGGTHANAYSNLPNVNLVGIVDVQLEKASLLAKELGTNSYKTYEEAIEEIGEVDIVSICLPTPLHLEFV
KKIADTKTHIICEKPLARTLEDAKEIIDYCNSKGVKLFVGHVVRFFKEYSRAKQLIEGGKIGKPAVVNTSRIGGFPDASN
DWYSNYSKSGGLVLDMIIHDFDFLRWCFGEVDHVYAKSSKGRVNSKLEYALVTLKFNNGVIAHVEGSWAHQKFTTKFDIA
GTEGILNYDSSKVSPVFKSIKELEGSHTGVAVPESPLKATPYQIQLEHFINCVIEEEKPIVTAIDAYKAMEIALAALKSI
DTGKVVEISNKEMGILL
>Mature_337_residues
MLNVLVIGSGTMGGTHANAYSNLPNVNLVGIVDVQLEKASLLAKELGTNSYKTYEEAIEEIGEVDIVSICLPTPLHLEFV
KKIADTKTHIICEKPLARTLEDAKEIIDYCNSKGVKLFVGHVVRFFKEYSRAKQLIEGGKIGKPAVVNTSRIGGFPDASN
DWYSNYSKSGGLVLDMIIHDFDFLRWCFGEVDHVYAKSSKGRVNSKLEYALVTLKFNNGVIAHVEGSWAHQKFTTKFDIA
GTEGILNYDSSKVSPVFKSIKELEGSHTGVAVPESPLKATPYQIQLEHFINCVIEEEKPIVTAIDAYKAMEIALAALKSI
DTGKVVEISNKEMGILL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=266, Percent_Identity=27.8195488721804, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787574, Length=194, Percent_Identity=28.3505154639175, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24581117, Length=233, Percent_Identity=28.755364806867, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37056; Mature: 37056

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNVLVIGSGTMGGTHANAYSNLPNVNLVGIVDVQLEKASLLAKELGTNSYKTYEEAIEE
CEEEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHH
IGEVDIVSICLPTPLHLEFVKKIADTKTHIICEKPLARTLEDAKEIIDYCNSKGVKLFVG
HCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEHHH
HVVRFFKEYSRAKQLIEGGKIGKPAVVNTSRIGGFPDASNDWYSNYSKSGGLVLDMIIHD
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCHHHCCCCCCCEEEHHHHHH
FDFLRWCFGEVDHVYAKSSKGRVNSKLEYALVTLKFNNGVIAHVEGSWAHQKFTTKFDIA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCCCCEEEECC
GTEGILNYDSSKVSPVFKSIKELEGSHTGVAVPESPLKATPYQIQLEHFINCVIEEEKPI
CCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCE
VTAIDAYKAMEIALAALKSIDTGKVVEISNKEMGILL
EEEHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MLNVLVIGSGTMGGTHANAYSNLPNVNLVGIVDVQLEKASLLAKELGTNSYKTYEEAIEE
CEEEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHH
IGEVDIVSICLPTPLHLEFVKKIADTKTHIICEKPLARTLEDAKEIIDYCNSKGVKLFVG
HCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEHHH
HVVRFFKEYSRAKQLIEGGKIGKPAVVNTSRIGGFPDASNDWYSNYSKSGGLVLDMIIHD
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCHHHCCCCCCCEEEHHHHHH
FDFLRWCFGEVDHVYAKSSKGRVNSKLEYALVTLKFNNGVIAHVEGSWAHQKFTTKFDIA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCCCCEEEECC
GTEGILNYDSSKVSPVFKSIKELEGSHTGVAVPESPLKATPYQIQLEHFINCVIEEEKPI
CCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCE
VTAIDAYKAMEIALAALKSIDTGKVVEISNKEMGILL
EEEHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]