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The map label for this gene is citT [H]

Identifier: 23100705

GI number: 23100705

Start: 3387612

End: 3388280

Strand: Reverse

Name: citT [H]

Synonym: OB3250

Alternate gene names: 23100705

Gene position: 3388280-3387612 (Counterclockwise)

Preceding gene: 23100706

Following gene: 23100704

Centisome position: 93.33

GC content: 37.07

Gene sequence:

>669_bases
ATGAATGTTCTTGTTGCAGAGGATGATTATCGGGTTGCCGATATTCATTGTCAATACTTAGAGAAGTTTCAAGATATACA
ATATATTGAAAGAGCTGCAACCGCGTATGAAACATTAGCCAAGTTAAAAGAAAACAAATTTGATTTATTATTATTGGATG
TATATTTGCCAGATGAGCTTGGTATTAATATGATTGAAACATATAAGCAAGAACACGCAGCACTGCAAATTATATTGATT
ACTGCAGCAACGGATATCGAAATGTTGAAGAAAGCATACCTTTCTGGTGTGATTGACTATTTAATAAAACCGATTGCGCT
TGATCGGCTAGCAGATGCGATAAATAAAGCAGTTAAAAATCACCAATTTATCCGTTCGCAAGGGGAATTTACGCAGCAAC
TGGCAGATCAGCTCTTTCAAAATCAACAAGAAATTATGGAAAAACAAGAATATCCAAAAGGAATTGATGAACTGACGCTT
AAGAAGGTGAACGAAGTATTGCAAAAACAATCCAGTGGCATGACAGCAGATCAAGTGGGAAAAGATATCGGCGTTTCCCG
CACTACTGCAAGAAGGTACTTGGAATACTTAATATCCGTTGGAAAAGCCAAAGCAGAATTGGAATATGGGATTGTAGGTC
GGCCAGAACGTAAATATGTCACGCAGTAA

Upstream 100 bases:

>100_bases
CAGCTTTATTAGAGTTACAAGGCTTTTTGGAAATAACAGCTAATGAACCGAATGGAACCGTATTTATCGTGTATATTCCG
AAAAAAGGGGGAGCGGAATC

Downstream 100 bases:

>100_bases
AAACAATGATCATTTAAATAGTAGAAGGAAAAATAGGCAATTTCTTCGGGTGCGAAGGTGAGCAATTTCTCGGAAAATCT
TATTTCCGAAAATGTTCCAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNVLVAEDDYRVADIHCQYLEKFQDIQYIERAATAYETLAKLKENKFDLLLLDVYLPDELGINMIETYKQEHAALQIILI
TAATDIEMLKKAYLSGVIDYLIKPIALDRLADAINKAVKNHQFIRSQGEFTQQLADQLFQNQQEIMEKQEYPKGIDELTL
KKVNEVLQKQSSGMTADQVGKDIGVSRTTARRYLEYLISVGKAKAELEYGIVGRPERKYVTQ

Sequences:

>Translated_222_residues
MNVLVAEDDYRVADIHCQYLEKFQDIQYIERAATAYETLAKLKENKFDLLLLDVYLPDELGINMIETYKQEHAALQIILI
TAATDIEMLKKAYLSGVIDYLIKPIALDRLADAINKAVKNHQFIRSQGEFTQQLADQLFQNQQEIMEKQEYPKGIDELTL
KKVNEVLQKQSSGMTADQVGKDIGVSRTTARRYLEYLISVGKAKAELEYGIVGRPERKYVTQ
>Mature_222_residues
MNVLVAEDDYRVADIHCQYLEKFQDIQYIERAATAYETLAKLKENKFDLLLLDVYLPDELGINMIETYKQEHAALQIILI
TAATDIEMLKKAYLSGVIDYLIKPIALDRLADAINKAVKNHQFIRSQGEFTQQLADQLFQNQQEIMEKQEYPKGIDELTL
KKVNEVLQKQSSGMTADQVGKDIGVSRTTARRYLEYLISVGKAKAELEYGIVGRPERKYVTQ

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=219, Percent_Identity=35.6164383561644, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790566, Length=233, Percent_Identity=27.8969957081545, Blast_Score=100, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25455; Mature: 25455

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVAEDDYRVADIHCQYLEKFQDIQYIERAATAYETLAKLKENKFDLLLLDVYLPDEL
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHH
GINMIETYKQEHAALQIILITAATDIEMLKKAYLSGVIDYLIKPIALDRLADAINKAVKN
CHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQFIRSQGEFTQQLADQLFQNQQEIMEKQEYPKGIDELTLKKVNEVLQKQSSGMTADQVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
KDIGVSRTTARRYLEYLISVGKAKAELEYGIVGRPERKYVTQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVLVAEDDYRVADIHCQYLEKFQDIQYIERAATAYETLAKLKENKFDLLLLDVYLPDEL
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHH
GINMIETYKQEHAALQIILITAATDIEMLKKAYLSGVIDYLIKPIALDRLADAINKAVKN
CHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQFIRSQGEFTQQLADQLFQNQQEIMEKQEYPKGIDELTLKKVNEVLQKQSSGMTADQVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
KDIGVSRTTARRYLEYLISVGKAKAELEYGIVGRPERKYVTQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]