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The map label for this gene is rbsR [H]

Identifier: 23100032

GI number: 23100032

Start: 2635331

End: 2636314

Strand: Reverse

Name: rbsR [H]

Synonym: OB2577

Alternate gene names: 23100032

Gene position: 2636314-2635331 (Counterclockwise)

Preceding gene: 23100035

Following gene: 23100031

Centisome position: 72.62

GC content: 37.3

Gene sequence:

>984_bases
ATGACAGTAACCATCAAAGATGTAGCTAAAGAAGCTGGTGTATCAGCTGCTACAGTCTCTAGAGTACTAAATAATAGTGG
GTATGTATATGAAGATACTCGGAAGGCAGTCATGGAAGCGATTAATCATTTGCAATATAAGCCTAATGAAGTGGCGCGAT
CGTTATATAAACGTACTTCTAAGTTAATTGGGCTTGTACTTCCTGATATTACCAATCCTTTTTTTCCTGCATTAGCAAGA
GGGGTGGAAGACAAGCTCCAACAGCTAGGCTATCGCGTTATTTTTGGGAATACGGATGGTGATGCTACAAAGGAAATGGA
CTATATTGATACATTTTTACAACATAACGTGGTTGGATTAATAGCTTCTGTTGATCGTTTACATCATGAAGTGCTAACTA
ATTTACGTGTGCCGGTTGTAACAGTCGATCGTACTACCGAAGAGCTTCCTGCAGTGTATGCAGACCATAAATCAGGAGGA
CGATTAGCTGCAGAAAAATTAGTACGATCGGCTTGTGAAAAAATAGTTGTTTTAAGAGGACCTCAAGACGCAAAACCGTT
ATATGACCGATTTCAATCAGCGACACAATATTTAAGTGAGAATAATGTTTCCTTCCATTATTTAGATTGTCAGCTATCTT
TTGAAGATGGGAGACAGAAAGCAAAAGAACTATTTGATCAATTCCCTGATACAGATGGTATTATTGCTTGTAATGATTTA
GTAGCTGCTGCAGTTTTACATGAGGCTGTAACAAGAGGAATTAGCGTACCAACTGATTTACAAGTAATCGGGTACGATAA
TATAACGATCAGTGAGATTGTTCATCCGAGTCTTACTACCATTCATCAGCCAACGTACGAGATGGGAATGAAAGCAGCAG
AAATGATTATAAAACTTATCAGCAAAGAAAAACTAAATACGATACATGAACAATTACCTGTTTTCATAAAAGAAAGAAAT
TCAACAGTAAATGGAGGAATATAG

Upstream 100 bases:

>100_bases
CTTCACAATAACAGGGGATATTTTCTATTGCTATCAAAACGCTTTCATGATAATATTTATCTGAAACCGGTTCCATATTT
TATTGAAGGAATGAATAAAA

Downstream 100 bases:

>100_bases
ATGGTAAACATAACTGTAGTGGGAAGCTCATCAATAGATTTAGTCGTAACAGCTCCAACAAGACCTAAAGCCGGAGAAAC
GATTATTGGTGATGATTTTC

Product: transcriptional repressor of ribose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTVTIKDVAKEAGVSAATVSRVLNNSGYVYEDTRKAVMEAINHLQYKPNEVARSLYKRTSKLIGLVLPDITNPFFPALAR
GVEDKLQQLGYRVIFGNTDGDATKEMDYIDTFLQHNVVGLIASVDRLHHEVLTNLRVPVVTVDRTTEELPAVYADHKSGG
RLAAEKLVRSACEKIVVLRGPQDAKPLYDRFQSATQYLSENNVSFHYLDCQLSFEDGRQKAKELFDQFPDTDGIIACNDL
VAAAVLHEAVTRGISVPTDLQVIGYDNITISEIVHPSLTTIHQPTYEMGMKAAEMIIKLISKEKLNTIHEQLPVFIKERN
STVNGGI

Sequences:

>Translated_327_residues
MTVTIKDVAKEAGVSAATVSRVLNNSGYVYEDTRKAVMEAINHLQYKPNEVARSLYKRTSKLIGLVLPDITNPFFPALAR
GVEDKLQQLGYRVIFGNTDGDATKEMDYIDTFLQHNVVGLIASVDRLHHEVLTNLRVPVVTVDRTTEELPAVYADHKSGG
RLAAEKLVRSACEKIVVLRGPQDAKPLYDRFQSATQYLSENNVSFHYLDCQLSFEDGRQKAKELFDQFPDTDGIIACNDL
VAAAVLHEAVTRGISVPTDLQVIGYDNITISEIVHPSLTTIHQPTYEMGMKAAEMIIKLISKEKLNTIHEQLPVFIKERN
STVNGGI
>Mature_326_residues
TVTIKDVAKEAGVSAATVSRVLNNSGYVYEDTRKAVMEAINHLQYKPNEVARSLYKRTSKLIGLVLPDITNPFFPALARG
VEDKLQQLGYRVIFGNTDGDATKEMDYIDTFLQHNVVGLIASVDRLHHEVLTNLRVPVVTVDRTTEELPAVYADHKSGGR
LAAEKLVRSACEKIVVLRGPQDAKPLYDRFQSATQYLSENNVSFHYLDCQLSFEDGRQKAKELFDQFPDTDGIIACNDLV
AAAVLHEAVTRGISVPTDLQVIGYDNITISEIVHPSLTTIHQPTYEMGMKAAEMIIKLISKEKLNTIHEQLPVFIKERNS
TVNGGI

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=327, Percent_Identity=31.4984709480122, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1790369, Length=303, Percent_Identity=31.3531353135314, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=30.6306306306306, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=32.2368421052632, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=31.2080536912752, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=28.8888888888889, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789068, Length=319, Percent_Identity=26.6457680250784, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786540, Length=331, Percent_Identity=27.190332326284, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI48994940, Length=309, Percent_Identity=25.5663430420712, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=25.2365930599369, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786268, Length=308, Percent_Identity=22.4025974025974, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787906, Length=333, Percent_Identity=24.024024024024, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790192, Length=282, Percent_Identity=25.177304964539, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36356; Mature: 36225

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTIKDVAKEAGVSAATVSRVLNNSGYVYEDTRKAVMEAINHLQYKPNEVARSLYKRTS
CEEEHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KLIGLVLPDITNPFFPALARGVEDKLQQLGYRVIFGNTDGDATKEMDYIDTFLQHNVVGL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IASVDRLHHEVLTNLRVPVVTVDRTTEELPAVYADHKSGGRLAAEKLVRSACEKIVVLRG
HHHHHHHHHHHHHCCCCCEEEECCCHHHHCHHHCCCCCCCHHHHHHHHHHHHHHEEEEEC
PQDAKPLYDRFQSATQYLSENNVSFHYLDCQLSFEDGRQKAKELFDQFPDTDGIIACNDL
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCEEEHHHH
VAAAVLHEAVTRGISVPTDLQVIGYDNITISEIVHPSLTTIHQPTYEMGMKAAEMIIKLI
HHHHHHHHHHHCCCCCCCCEEEEECCCEEHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHH
SKEKLNTIHEQLPVFIKERNSTVNGGI
HHHHHHHHHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
TVTIKDVAKEAGVSAATVSRVLNNSGYVYEDTRKAVMEAINHLQYKPNEVARSLYKRTS
EEEHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KLIGLVLPDITNPFFPALARGVEDKLQQLGYRVIFGNTDGDATKEMDYIDTFLQHNVVGL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IASVDRLHHEVLTNLRVPVVTVDRTTEELPAVYADHKSGGRLAAEKLVRSACEKIVVLRG
HHHHHHHHHHHHHCCCCCEEEECCCHHHHCHHHCCCCCCCHHHHHHHHHHHHHHEEEEEC
PQDAKPLYDRFQSATQYLSENNVSFHYLDCQLSFEDGRQKAKELFDQFPDTDGIIACNDL
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCEEEHHHH
VAAAVLHEAVTRGISVPTDLQVIGYDNITISEIVHPSLTTIHQPTYEMGMKAAEMIIKLI
HHHHHHHHHHHCCCCCCCCEEEEECCCEEHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHH
SKEKLNTIHEQLPVFIKERNSTVNGGI
HHHHHHHHHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]