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The map label for this gene is rbsK [H]

Identifier: 23100031

GI number: 23100031

Start: 2634458

End: 2635330

Strand: Reverse

Name: rbsK [H]

Synonym: OB2576

Alternate gene names: 23100031

Gene position: 2635330-2634458 (Counterclockwise)

Preceding gene: 23100032

Following gene: 23100030

Centisome position: 72.59

GC content: 37.46

Gene sequence:

>873_bases
ATGGTAAACATAACTGTAGTGGGAAGCTCATCAATAGATTTAGTCGTAACAGCTCCAACAAGACCTAAAGCCGGAGAAAC
GATTATTGGTGATGATTTTCAAACGGTGCCAGGTGGTAAAGGTGCAAATCAAGCAGTAGCTGCATCTCGATTAGGAGCGA
ATGTATCTATGATTGGTAGAGTAGGAAAGGATACGTTTGGCGAAGAAATTTTAAGCAATTTACAAGAAAATAAAGTTTCT
GTGGAATATGTGGAACCGGTTACCGATGTTGCTTCAGGAACTGCACATATTACGTTAGCAGAAGATGATAATAGCATTAT
TTTTGTAAAAGGTGCGAATGATTATGTTACACCAGACTATATAAAAAAATCGCTGGATAAGTTGATAAATGCGGACATTG
TATTAATTCAACAAGAAATTCCTGAAGAGACGGTAGAGTTTGTAATTGAAACTTGTCATACATACGAAGTTCCAATTTTA
TTAAATCCAGCTCCTGCAAGAGAAGTGTCCAATCAAGTAATAGAACGTACCACTTATCTTACTCCAAATGAACATGAATT
TTCGATTATGTTTGGCAATGAGAATAGAAGCGACGTATTAAAACGCTATCCCAATAAATTATTGATTACCGAGGGGAAAA
ATGGTGTACGTTACTTTGATGGTGAAGCAGAAATAGTTATTCCTTCTTATGAAGTAGTACCAGTAGATACAACAGGTGCA
GGAGATACTTTCAATGCTTCTTTCGCAATAGCGATTGCAGAAGGAAGATCCTTAGAGGATGCAATTCGTTTTGCGAATAA
GGCTGCATCGATATCAATTACAAAATTTGGTGCACAAGGCGGGATGCCAACTCGAACAGAGATGGAGGAATAA

Upstream 100 bases:

>100_bases
GATTATAAAACTTATCAGCAAAGAAAAACTAAATACGATACATGAACAATTACCTGTTTTCATAAAAGAAAGAAATTCAA
CAGTAAATGGAGGAATATAG

Downstream 100 bases:

>100_bases
AGTATATGAAGAAAAAAGGTATGTTAAACAGCGAAATATCAAAAGTTTTATCAGATTTGGGACATACCGATCAAATTGTT
ATTGCCGATGCAGGCTTACC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MVNITVVGSSSIDLVVTAPTRPKAGETIIGDDFQTVPGGKGANQAVAASRLGANVSMIGRVGKDTFGEEILSNLQENKVS
VEYVEPVTDVASGTAHITLAEDDNSIIFVKGANDYVTPDYIKKSLDKLINADIVLIQQEIPEETVEFVIETCHTYEVPIL
LNPAPAREVSNQVIERTTYLTPNEHEFSIMFGNENRSDVLKRYPNKLLITEGKNGVRYFDGEAEIVIPSYEVVPVDTTGA
GDTFNASFAIAIAEGRSLEDAIRFANKAASISITKFGAQGGMPTRTEMEE

Sequences:

>Translated_290_residues
MVNITVVGSSSIDLVVTAPTRPKAGETIIGDDFQTVPGGKGANQAVAASRLGANVSMIGRVGKDTFGEEILSNLQENKVS
VEYVEPVTDVASGTAHITLAEDDNSIIFVKGANDYVTPDYIKKSLDKLINADIVLIQQEIPEETVEFVIETCHTYEVPIL
LNPAPAREVSNQVIERTTYLTPNEHEFSIMFGNENRSDVLKRYPNKLLITEGKNGVRYFDGEAEIVIPSYEVVPVDTTGA
GDTFNASFAIAIAEGRSLEDAIRFANKAASISITKFGAQGGMPTRTEMEE
>Mature_290_residues
MVNITVVGSSSIDLVVTAPTRPKAGETIIGDDFQTVPGGKGANQAVAASRLGANVSMIGRVGKDTFGEEILSNLQENKVS
VEYVEPVTDVASGTAHITLAEDDNSIIFVKGANDYVTPDYIKKSLDKLINADIVLIQQEIPEETVEFVIETCHTYEVPIL
LNPAPAREVSNQVIERTTYLTPNEHEFSIMFGNENRSDVLKRYPNKLLITEGKNGVRYFDGEAEIVIPSYEVVPVDTTGA
GDTFNASFAIAIAEGRSLEDAIRFANKAASISITKFGAQGGMPTRTEMEE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=35.472972972973, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1790193, Length=298, Percent_Identity=35.9060402684564, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI87081971, Length=311, Percent_Identity=23.4726688102894, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI87082343, Length=291, Percent_Identity=24.7422680412371, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788491, Length=293, Percent_Identity=25.2559726962457, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789432, Length=302, Percent_Identity=25.1655629139073, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788484, Length=283, Percent_Identity=24.3816254416961, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=292, Percent_Identity=35.958904109589, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=31.044776119403, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=32.3333333333333, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24583886, Length=302, Percent_Identity=27.8145695364238, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31362; Mature: 31362

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNITVVGSSSIDLVVTAPTRPKAGETIIGDDFQTVPGGKGANQAVAASRLGANVSMIGR
CEEEEEECCCCEEEEEECCCCCCCCCEEECCCCEECCCCCCCCHHHHHHHHCCCCEEEEC
VGKDTFGEEILSNLQENKVSVEYVEPVTDVASGTAHITLAEDDNSIIFVKGANDYVTPDY
CCCCHHHHHHHHHHHHCCEEEEEECCHHHHCCCEEEEEEEECCCCEEEEECCCCCCCHHH
IKKSLDKLINADIVLIQQEIPEETVEFVIETCHTYEVPILLNPAPAREVSNQVIERTTYL
HHHHHHHHHCCCEEEEEHHCCHHHHHHHHHHHCEEECCEEECCCCHHHHHHHHHHHHCCC
TPNEHEFSIMFGNENRSDVLKRYPNKLLITEGKNGVRYFDGEAEIVIPSYEVVPVDTTGA
CCCCCEEEEEECCCCHHHHHHHCCCEEEEEECCCCCEEECCCEEEEECCEEEEEECCCCC
GDTFNASFAIAIAEGRSLEDAIRFANKAASISITKFGAQGGMPTRTEMEE
CCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MVNITVVGSSSIDLVVTAPTRPKAGETIIGDDFQTVPGGKGANQAVAASRLGANVSMIGR
CEEEEEECCCCEEEEEECCCCCCCCCEEECCCCEECCCCCCCCHHHHHHHHCCCCEEEEC
VGKDTFGEEILSNLQENKVSVEYVEPVTDVASGTAHITLAEDDNSIIFVKGANDYVTPDY
CCCCHHHHHHHHHHHHCCEEEEEECCHHHHCCCEEEEEEEECCCCEEEEECCCCCCCHHH
IKKSLDKLINADIVLIQQEIPEETVEFVIETCHTYEVPILLNPAPAREVSNQVIERTTYL
HHHHHHHHHCCCEEEEEHHCCHHHHHHHHHHHCEEECCEEECCCCHHHHHHHHHHHHCCC
TPNEHEFSIMFGNENRSDVLKRYPNKLLITEGKNGVRYFDGEAEIVIPSYEVVPVDTTGA
CCCCCEEEEEECCCCHHHHHHHCCCEEEEEECCCCCEEECCCEEEEECCEEEEEECCCCC
GDTFNASFAIAIAEGRSLEDAIRFANKAASISITKFGAQGGMPTRTEMEE
CCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]