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The map label for this gene is malR [H]

Identifier: 23100022

GI number: 23100022

Start: 2625185

End: 2626207

Strand: Reverse

Name: malR [H]

Synonym: OB2567

Alternate gene names: 23100022

Gene position: 2626207-2625185 (Counterclockwise)

Preceding gene: 23100023

Following gene: 23100021

Centisome position: 72.34

GC content: 32.26

Gene sequence:

>1023_bases
GTGTCGGTTACTATAAAAGACGTCGCAAAGGAAGCAAATGTATCGCCTTCTACCGTTTCTCGAGTTCTTTCTGATAGTGA
TAAGATAAGTGAAAAGACGAAAAGAAAAGTAAGAAAAGTTATGAATGAATTAGGTTATCATATTAATTACAATGCGAGAG
TACTTGTTCAAAAATCTACCAAAACAATAGGAATTGTGATGAAACACTCAGCTACTCATTCTTGGCATAATCCATTTTTT
CCTGAAGTGTTAAGGGGGATTAGTACCTATTGTCACAAACTAGATTATAGTATTTCTTTAACTACCGGAGAATCAGAGGA
ATCTATCTATAAAGAGGTAGTGAAGATGGTACACGGAAAACGAATAGACGGCATCATCGTACTTTATTCAAAGAAAGATG
ATAAAGTTGTACCGTTTTTGATAGAACAACAAGTACCTTTTGTTGTCATTGGGAAGCCAATGGAGCATACAAATGAAATT
ATGTATGTTGATAATGATAATGTTCAAGCAGGAAAAGAAGCAGCTGAATTTCTTATCGATCTTGGTCATGAAGAAATAGG
TTTTATTGGAGATAATCCAGATTTCCAAGTTATTCAAGATAGAATGAATGGATTTAAAGAAGCTTTGTTATCAAACGATT
TATTTTATCGTGATGAATACATTAAATACGTAGATGATAATAATAATCGGAAAATCGTTACGGAATTATTTAATCAAGAG
ATTACTCCAACTGCACTTGTTATTTCTTCTGATATTCAAGCTATTGGTATATTAAAATTATTGCATGAAATAGGTTATCG
TGTTCCTGATGATATTAGTATCGTGACATTCAATAAAACGTTTATTACGGAATTATCGATACCATCATTAACAACGGTCA
ATACGCAAACATATCAATTAGGTTATGAATCATCCAGATGTTTAATAGAGCTAATCAATGAACCCGAAATGTTTAAACGA
AGCGTGATTATACCTACAGTCATAGAGGTAAATGATTCACATCAGAAGGTATTAAAAGTGTAA

Upstream 100 bases:

>100_bases
ATTATAATTTACTTTATTGCACAGAAACATATTATTAAAGGAGTATCAGATGGAGCTGTTAAGGTAATCCCTAGAAATAA
ATGAAAGGAGGCTGATTACC

Downstream 100 bases:

>100_bases
TAATATTTTTTATTTTGATAGCGCATGCATTAATTATCAATAAGGAGAGGTTAGAAATGAACGTAGTTGTTTGGAATGAA
AATCGACATGAAAAACAAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSVTIKDVAKEANVSPSTVSRVLSDSDKISEKTKRKVRKVMNELGYHINYNARVLVQKSTKTIGIVMKHSATHSWHNPFF
PEVLRGISTYCHKLDYSISLTTGESEESIYKEVVKMVHGKRIDGIIVLYSKKDDKVVPFLIEQQVPFVVIGKPMEHTNEI
MYVDNDNVQAGKEAAEFLIDLGHEEIGFIGDNPDFQVIQDRMNGFKEALLSNDLFYRDEYIKYVDDNNNRKIVTELFNQE
ITPTALVISSDIQAIGILKLLHEIGYRVPDDISIVTFNKTFITELSIPSLTTVNTQTYQLGYESSRCLIELINEPEMFKR
SVIIPTVIEVNDSHQKVLKV

Sequences:

>Translated_340_residues
MSVTIKDVAKEANVSPSTVSRVLSDSDKISEKTKRKVRKVMNELGYHINYNARVLVQKSTKTIGIVMKHSATHSWHNPFF
PEVLRGISTYCHKLDYSISLTTGESEESIYKEVVKMVHGKRIDGIIVLYSKKDDKVVPFLIEQQVPFVVIGKPMEHTNEI
MYVDNDNVQAGKEAAEFLIDLGHEEIGFIGDNPDFQVIQDRMNGFKEALLSNDLFYRDEYIKYVDDNNNRKIVTELFNQE
ITPTALVISSDIQAIGILKLLHEIGYRVPDDISIVTFNKTFITELSIPSLTTVNTQTYQLGYESSRCLIELINEPEMFKR
SVIIPTVIEVNDSHQKVLKV
>Mature_339_residues
SVTIKDVAKEANVSPSTVSRVLSDSDKISEKTKRKVRKVMNELGYHINYNARVLVQKSTKTIGIVMKHSATHSWHNPFFP
EVLRGISTYCHKLDYSISLTTGESEESIYKEVVKMVHGKRIDGIIVLYSKKDDKVVPFLIEQQVPFVVIGKPMEHTNEIM
YVDNDNVQAGKEAAEFLIDLGHEEIGFIGDNPDFQVIQDRMNGFKEALLSNDLFYRDEYIKYVDDNNNRKIVTELFNQEI
TPTALVISSDIQAIGILKLLHEIGYRVPDDISIVTFNKTFITELSIPSLTTVNTQTYQLGYESSRCLIELINEPEMFKRS
VIIPTVIEVNDSHQKVLKV

Specific function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=29.6529968454259, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1790369, Length=315, Percent_Identity=29.2063492063492, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=27.4924471299094, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=27.027027027027, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=27.9863481228669, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789068, Length=298, Percent_Identity=29.5302013422819, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786540, Length=336, Percent_Identity=27.0833333333333, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788474, Length=295, Percent_Identity=26.7796610169492, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=23.5820895522388, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789456, Length=342, Percent_Identity=26.0233918128655, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI48994940, Length=315, Percent_Identity=24.1269841269841, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790715, Length=324, Percent_Identity=25, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790689, Length=335, Percent_Identity=23.8805970149254, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38719; Mature: 38588

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTIKDVAKEANVSPSTVSRVLSDSDKISEKTKRKVRKVMNELGYHINYNARVLVQKST
CCEEHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECC
KTIGIVMKHSATHSWHNPFFPEVLRGISTYCHKLDYSISLTTGESEESIYKEVVKMVHGK
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCC
RIDGIIVLYSKKDDKVVPFLIEQQVPFVVIGKPMEHTNEIMYVDNDNVQAGKEAAEFLID
CCCEEEEEEECCCCCCCCEEECCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHH
LGHEEIGFIGDNPDFQVIQDRMNGFKEALLSNDLFYRDEYIKYVDDNNNRKIVTELFNQE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCHHHHHHCCC
ITPTALVISSDIQAIGILKLLHEIGYRVPDDISIVTFNKTFITELSIPSLTTVNTQTYQL
CCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCEEEECCEEEEE
GYESSRCLIELINEPEMFKRSVIIPTVIEVNDSHQKVLKV
CCCCCHHHHHHHCCHHHHHCCEECCEEEEECCCHHHHHCC
>Mature Secondary Structure 
SVTIKDVAKEANVSPSTVSRVLSDSDKISEKTKRKVRKVMNELGYHINYNARVLVQKST
CEEHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECC
KTIGIVMKHSATHSWHNPFFPEVLRGISTYCHKLDYSISLTTGESEESIYKEVVKMVHGK
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCC
RIDGIIVLYSKKDDKVVPFLIEQQVPFVVIGKPMEHTNEIMYVDNDNVQAGKEAAEFLID
CCCEEEEEEECCCCCCCCEEECCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHH
LGHEEIGFIGDNPDFQVIQDRMNGFKEALLSNDLFYRDEYIKYVDDNNNRKIVTELFNQE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCHHHHHHCCC
ITPTALVISSDIQAIGILKLLHEIGYRVPDDISIVTFNKTFITELSIPSLTTVNTQTYQL
CCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCEEEECCEEEEE
GYESSRCLIELINEPEMFKRSVIIPTVIEVNDSHQKVLKV
CCCCCHHHHHHHCCHHHHHCCEECCEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]