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The map label for this gene is lgt

Identifier: 23099936

GI number: 23099936

Start: 2537525

End: 2538388

Strand: Reverse

Name: lgt

Synonym: OB2481

Alternate gene names: 23099936

Gene position: 2538388-2537525 (Counterclockwise)

Preceding gene: 23099937

Following gene: 23099935

Centisome position: 69.92

GC content: 34.38

Gene sequence:

>864_bases
ATGCTACATACTGCGGCACCAATTGATAGAGTAGCTATTGAAATTGGCCCTCTTTCAATATATTGGTATGGTATAATTAT
TGCATTTGGCGCTATATTAGCAATTTATCTTGCTTCTAAAGAAGCAGATCGACTTGGTTTAACAAAGGATTTAATGTTAG
ATTTTGTCATGTTTGCAGTGCCAATCGCAATAATCTTTGCAAGAATTTATTATGTGTTTTTTGAATTTGATCAATATGCT
AATGGTCCTTGGTGGAAAGTTTTTGCGATCTGGGAAGGCGGAATTGCAATCCATGGGGCGGTAATTGGAGGCGTAATAAC
TGCGATTGTTTTTGCTAAAGTAAGAAAGGTTTCTTTTTGGCAAATAGCTGATATTGTTGCCCCTAGCCTCATATTAGGAC
AGGCGATTGGAAGATGGGGGAATTTTGTAAACCAAGAAGCTCATGGTGGACCAATTTCACAAGCTACATATGAAAGCTTT
CATCAATACTTGCCTGATTTTATCATGAATCAAATGACCATTAATGGGGTTATGTATCATCCGACCTTCTTATATGAATC
GGTTTGGAATATATTAATCTTTGTGGGGTTATTGCTCCTACGTAAGTACAATCCTGTACGAGGTGAAGTATTCTTAACTT
ATGCTATTACGTATTCGATTGGTAGGTATTTTATTGAAGGATTACGTACAGACAGTCTGTATATGTTCGATATAATTCGT
ACAGCACAATTTATTTCTATATTAATTATCATTGTATCTATTATTTTCATTATTTATCGTCGTAAAACAGTTAGTGAGCG
ATATTTAGACGCACCACCTAGTAACAAAAAGAAAAATAAAAAGTCAACTAAAAAGAAAAAATAA

Upstream 100 bases:

>100_bases
TTCGTCTAAAGCGAATGGGAGTCAATACAGCAGAAGAATTCTCAGAAAGATTGTCTACCATGATTGAAAAAGGTGAGCTT
GAATAGAGGAGGAATAGACT

Downstream 100 bases:

>100_bases
AGGTTCAACATGACTAGTCAGGGGATGAAAAACATGTCTGGCACTTTACAAAGAGGGTTTCGGGAAGGAATTAATACTAC
ATGGAAATTAGGGAAAATTA

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLHTAAPIDRVAIEIGPLSIYWYGIIIAFGAILAIYLASKEADRLGLTKDLMLDFVMFAVPIAIIFARIYYVFFEFDQYA
NGPWWKVFAIWEGGIAIHGAVIGGVITAIVFAKVRKVSFWQIADIVAPSLILGQAIGRWGNFVNQEAHGGPISQATYESF
HQYLPDFIMNQMTINGVMYHPTFLYESVWNILIFVGLLLLRKYNPVRGEVFLTYAITYSIGRYFIEGLRTDSLYMFDIIR
TAQFISILIIIVSIIFIIYRRKTVSERYLDAPPSNKKKNKKSTKKKK

Sequences:

>Translated_287_residues
MLHTAAPIDRVAIEIGPLSIYWYGIIIAFGAILAIYLASKEADRLGLTKDLMLDFVMFAVPIAIIFARIYYVFFEFDQYA
NGPWWKVFAIWEGGIAIHGAVIGGVITAIVFAKVRKVSFWQIADIVAPSLILGQAIGRWGNFVNQEAHGGPISQATYESF
HQYLPDFIMNQMTINGVMYHPTFLYESVWNILIFVGLLLLRKYNPVRGEVFLTYAITYSIGRYFIEGLRTDSLYMFDIIR
TAQFISILIIIVSIIFIIYRRKTVSERYLDAPPSNKKKNKKSTKKKK
>Mature_287_residues
MLHTAAPIDRVAIEIGPLSIYWYGIIIAFGAILAIYLASKEADRLGLTKDLMLDFVMFAVPIAIIFARIYYVFFEFDQYA
NGPWWKVFAIWEGGIAIHGAVIGGVITAIVFAKVRKVSFWQIADIVAPSLILGQAIGRWGNFVNQEAHGGPISQATYESF
HQYLPDFIMNQMTINGVMYHPTFLYESVWNILIFVGLLLLRKYNPVRGEVFLTYAITYSIGRYFIEGLRTDSLYMFDIIR
TAQFISILIIIVSIIFIIYRRKTVSERYLDAPPSNKKKNKKSTKKKK

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=276, Percent_Identity=31.1594202898551, Blast_Score=104, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_OCEIH (Q8CX97)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693402.1
- GeneID:   1015342
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2481
- NMPDR:   fig|221109.1.peg.2480
- HOGENOM:   HBG450278
- OMA:   TSHIRVA
- BioCyc:   OIHE221109:OB2481-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 32763; Mature: 32763

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x108364b8)-; HASH(0xd5b7eec)-; HASH(0xd5b7cd0)-; HASH(0x107ba414)-; HASH(0x10b89e5c)-; HASH(0x10b7f274)-; HASH(0x10b7136c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHTAAPIDRVAIEIGPLSIYWYGIIIAFGAILAIYLASKEADRLGLTKDLMLDFVMFAV
CCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHH
PIAIIFARIYYVFFEFDQYANGPWWKVFAIWEGGIAIHGAVIGGVITAIVFAKVRKVSFW
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHH
QIADIVAPSLILGQAIGRWGNFVNQEAHGGPISQATYESFHQYLPDFIMNQMTINGVMYH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEC
PTFLYESVWNILIFVGLLLLRKYNPVRGEVFLTYAITYSIGRYFIEGLRTDSLYMFDIIR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHH
TAQFISILIIIVSIIFIIYRRKTVSERYLDAPPSNKKKNKKSTKKKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MLHTAAPIDRVAIEIGPLSIYWYGIIIAFGAILAIYLASKEADRLGLTKDLMLDFVMFAV
CCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHH
PIAIIFARIYYVFFEFDQYANGPWWKVFAIWEGGIAIHGAVIGGVITAIVFAKVRKVSFW
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHH
QIADIVAPSLILGQAIGRWGNFVNQEAHGGPISQATYESFHQYLPDFIMNQMTINGVMYH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEC
PTFLYESVWNILIFVGLLLLRKYNPVRGEVFLTYAITYSIGRYFIEGLRTDSLYMFDIIR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHH
TAQFISILIIIVSIIFIIYRRKTVSERYLDAPPSNKKKNKKSTKKKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376