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The map label for this gene is gap [H]

Identifier: 23099615

GI number: 23099615

Start: 2192155

End: 2193180

Strand: Reverse

Name: gap [H]

Synonym: OB2160

Alternate gene names: 23099615

Gene position: 2193180-2192155 (Counterclockwise)

Preceding gene: 23099616

Following gene: 23099614

Centisome position: 60.41

GC content: 35.19

Gene sequence:

>1026_bases
ATGAATACAAAACGTATCGCAATTACTGGATTTGGTCGAATAGGGAGAATGATTTTTCGACAAGCAATACAAAATGATCA
GTTTGAAGTTGTCGCTATCAATGCTAGTTATCCAGCTGAAACATTAGCACACATGGTGAAATATGATAGTGTCCATGGAA
TTTTTGATGGAGATGTGAAAGCGCTTGAAGGATATTTAGAAATAGATGGTAAAAAAGTGGAAATTGTAAACAATAGACAG
CCTGAACTTCTCCCTTGGAAGAAGTTAGATATTGATATTGTTATTGAAGCTACCGGGAAATTTAATTCTAAAGAAGCAGC
TGGATTGCATATTAAAGCAGGTGCAAAAAAAGTAATTATAACTGCTCCAGGCAAACAAGTAGATAAAACAATTGTAATGG
GAGTTAATGAAGCTGCATATATTCCTGAAAGTGATGATGTCATTTCAAATGCATCATGTACAACGAATTGTTTGGCCCCC
GTTGTAAAAGTGATAGATGATCATTTTACGATAAAAAATGGCTTAATGACAACCGTCCATGCTTTTACGAATGATCAAAA
GAATTTAGATAACCCACATAAAGATTTACGAAGAGCAAGAGGATGCACACAATCAATTATTCCGACAACAACAGGTGCTG
CAAAGGCACTTGGGGAAGTTTTGCCGCACTTAAATGGAAAATTACATGGTATGGCTTTAAGAGTGCCAACCCCAAACGTA
TCTTTGGTAGATTTAGTCATTGATGTAGAAGAAAATGTTACAGTAGAACAACTAAACCAATTATTTAAGGATGCTTCAAA
AGGATATATGAAGGGAGTATTGGAATACTCGGATGAACCTCTCGTATCTATTGATTATACAACAAGTGATTTTTCCGCTA
TAATTGATGGGTTATCCACCATTGTAATGGAAGGCAAAAAAATAAAGGTAATTGCTTGGTATGATAATGAATGGGGATAC
TCTAAACGTGTTCTTGATTTAGCTCTTTATGTAGGGGACCGCTTAAAAAAAGAAATGAAAGTATGA

Upstream 100 bases:

>100_bases
GCCTCTTTTTCGTTGTTTTTAACACATTAACGATAATTTGTGTTATACTAATTATGCATAAAAGGTTATGAGTATATCAT
AATTAGGGGGATTATTTCTT

Downstream 100 bases:

>100_bases
AGAAATATATAAACAATAAATAGAAACGAACAATGAATAGGAGAAGATTATTTATTCTCTACCATTGTTCGTTTTTTATT
TTTGGAATCTATACCGTGAT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNTKRIAITGFGRIGRMIFRQAIQNDQFEVVAINASYPAETLAHMVKYDSVHGIFDGDVKALEGYLEIDGKKVEIVNNRQ
PELLPWKKLDIDIVIEATGKFNSKEAAGLHIKAGAKKVIITAPGKQVDKTIVMGVNEAAYIPESDDVISNASCTTNCLAP
VVKVIDDHFTIKNGLMTTVHAFTNDQKNLDNPHKDLRRARGCTQSIIPTTTGAAKALGEVLPHLNGKLHGMALRVPTPNV
SLVDLVIDVEENVTVEQLNQLFKDASKGYMKGVLEYSDEPLVSIDYTTSDFSAIIDGLSTIVMEGKKIKVIAWYDNEWGY
SKRVLDLALYVGDRLKKEMKV

Sequences:

>Translated_341_residues
MNTKRIAITGFGRIGRMIFRQAIQNDQFEVVAINASYPAETLAHMVKYDSVHGIFDGDVKALEGYLEIDGKKVEIVNNRQ
PELLPWKKLDIDIVIEATGKFNSKEAAGLHIKAGAKKVIITAPGKQVDKTIVMGVNEAAYIPESDDVISNASCTTNCLAP
VVKVIDDHFTIKNGLMTTVHAFTNDQKNLDNPHKDLRRARGCTQSIIPTTTGAAKALGEVLPHLNGKLHGMALRVPTPNV
SLVDLVIDVEENVTVEQLNQLFKDASKGYMKGVLEYSDEPLVSIDYTTSDFSAIIDGLSTIVMEGKKIKVIAWYDNEWGY
SKRVLDLALYVGDRLKKEMKV
>Mature_341_residues
MNTKRIAITGFGRIGRMIFRQAIQNDQFEVVAINASYPAETLAHMVKYDSVHGIFDGDVKALEGYLEIDGKKVEIVNNRQ
PELLPWKKLDIDIVIEATGKFNSKEAAGLHIKAGAKKVIITAPGKQVDKTIVMGVNEAAYIPESDDVISNASCTTNCLAP
VVKVIDDHFTIKNGLMTTVHAFTNDQKNLDNPHKDLRRARGCTQSIIPTTTGAAKALGEVLPHLNGKLHGMALRVPTPNV
SLVDLVIDVEENVTVEQLNQLFKDASKGYMKGVLEYSDEPLVSIDYTTSDFSAIIDGLSTIVMEGKKIKVIAWYDNEWGY
SKRVLDLALYVGDRLKKEMKV

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=45.5357142857143, Blast_Score=296, Evalue=1e-80,
Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=44.4444444444444, Blast_Score=292, Evalue=3e-79,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=50, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=40.4833836858006, Blast_Score=273, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI17534677, Length=341, Percent_Identity=45.7478005865103, Blast_Score=310, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI17534679, Length=341, Percent_Identity=46.0410557184751, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=45.4545454545455, Blast_Score=301, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=45.4545454545455, Blast_Score=301, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=49.5440729483283, Blast_Score=318, Evalue=6e-88,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=48.1818181818182, Blast_Score=312, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=47.7203647416413, Blast_Score=309, Evalue=5e-85,
Organism=Drosophila melanogaster, GI85725000, Length=329, Percent_Identity=47.7203647416413, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI22023983, Length=329, Percent_Identity=47.7203647416413, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=46.5045592705167, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=46.5045592705167, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=46.177370030581, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 37614; Mature: 37614

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKRIAITGFGRIGRMIFRQAIQNDQFEVVAINASYPAETLAHMVKYDSVHGIFDGDVK
CCCCEEEEEECHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHH
ALEGYLEIDGKKVEIVNNRQPELLPWKKLDIDIVIEATGKFNSKEAAGLHIKAGAKKVII
HHCCEEEECCEEEEEECCCCCCCCCCEECCEEEEEEECCCCCCCCCCCEEEECCCCEEEE
TAPGKQVDKTIVMGVNEAAYIPESDDVISNASCTTNCLAPVVKVIDDHFTIKNGLMTTVH
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCEEEEH
AFTNDQKNLDNPHKDLRRARGCTQSIIPTTTGAAKALGEVLPHLNGKLHGMALRVPTPNV
HHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCC
SLVDLVIDVEENVTVEQLNQLFKDASKGYMKGVLEYSDEPLVSIDYTTSDFSAIIDGLST
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHH
IVMEGKKIKVIAWYDNEWGYSKRVLDLALYVGDRLKKEMKV
HHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTKRIAITGFGRIGRMIFRQAIQNDQFEVVAINASYPAETLAHMVKYDSVHGIFDGDVK
CCCCEEEEEECHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHH
ALEGYLEIDGKKVEIVNNRQPELLPWKKLDIDIVIEATGKFNSKEAAGLHIKAGAKKVII
HHCCEEEECCEEEEEECCCCCCCCCCEECCEEEEEEECCCCCCCCCCCEEEECCCCEEEE
TAPGKQVDKTIVMGVNEAAYIPESDDVISNASCTTNCLAPVVKVIDDHFTIKNGLMTTVH
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCEEEEH
AFTNDQKNLDNPHKDLRRARGCTQSIIPTTTGAAKALGEVLPHLNGKLHGMALRVPTPNV
HHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCC
SLVDLVIDVEENVTVEQLNQLFKDASKGYMKGVLEYSDEPLVSIDYTTSDFSAIIDGLST
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHH
IVMEGKKIKVIAWYDNEWGYSKRVLDLALYVGDRLKKEMKV
HHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]