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The map label for this gene is yggV [C]

Identifier: 23099560

GI number: 23099560

Start: 2139743

End: 2140336

Strand: Reverse

Name: yggV [C]

Synonym: OB2105

Alternate gene names: 23099560

Gene position: 2140336-2139743 (Counterclockwise)

Preceding gene: 23099561

Following gene: 23099559

Centisome position: 58.95

GC content: 34.51

Gene sequence:

>594_bases
ATGAAAAAAATAATTGTTGCTACTAAAAATAAAGGAAAGGCAAAAGAATTTAAAGAATTTTTTGCTAGCTTTGATATAGA
AGCAATATCACTATTGGATTTACCTGAATCTATTCCCGATATTGAGGAAACAGGTACCACTTTTGAAGAAAATGCAGCCT
TAAAAGCAGAGCAAATTAGTGAACGCTTTAATACAGCTGTTATTGCAGATGATTCAGGTTTGTTAATCGATGCTCTAGAT
GGACGACCTGGGCTATATTCTGCACGGTATGCCGGTGAGCCGACTAATGATCAAGCAAATATCGAGAAGGTACTAAAAGA
AATGCAGGATGTTCCCGATAATGATCGAAGTGCAAGATTTATTTGTGTATTAGCTATAGCTCAACCAGGTAAAGAAACTA
ACTTTTGTACAGGTTATTGTGAAGGACACATTCATAGTAAACAAAAAGGCGATCATGGATTTGGATACGATCCTATCTTT
ATTCCAAAAAAGTATGATGTGACAATGGCTGAATTAGATCCAGCTAAAAAGAATCAAATTAGTCATCGTAAAAATGCGAT
TGATCAGCTAGAAAAATGGTTACATACAATATAA

Upstream 100 bases:

>100_bases
AGAAGAAGGTATTCAACAGTTGGTGAAAATACAAAAGGAACTATTAGCAGATAAATTACTTATAGATTGAAAAGTGAATG
ATAAGGGTGTGCTCAATCAT

Downstream 100 bases:

>100_bases
GTCACCAAATGGAGGGATTACGATGACTCGTGTATTAATAACTAGTGATAGTCATGGTTTGACACAGGAGTTAACGGAAA
TTATGAATCAACACGAGGTT

Product: hypothetical protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKKIIVATKNKGKAKEFKEFFASFDIEAISLLDLPESIPDIEETGTTFEENAALKAEQISERFNTAVIADDSGLLIDALD
GRPGLYSARYAGEPTNDQANIEKVLKEMQDVPDNDRSARFICVLAIAQPGKETNFCTGYCEGHIHSKQKGDHGFGYDPIF
IPKKYDVTMAELDPAKKNQISHRKNAIDQLEKWLHTI

Sequences:

>Translated_197_residues
MKKIIVATKNKGKAKEFKEFFASFDIEAISLLDLPESIPDIEETGTTFEENAALKAEQISERFNTAVIADDSGLLIDALD
GRPGLYSARYAGEPTNDQANIEKVLKEMQDVPDNDRSARFICVLAIAQPGKETNFCTGYCEGHIHSKQKGDHGFGYDPIF
IPKKYDVTMAELDPAKKNQISHRKNAIDQLEKWLHTI
>Mature_197_residues
MKKIIVATKNKGKAKEFKEFFASFDIEAISLLDLPESIPDIEETGTTFEENAALKAEQISERFNTAVIADDSGLLIDALD
GRPGLYSARYAGEPTNDQANIEKVLKEMQDVPDNDRSARFICVLAIAQPGKETNFCTGYCEGHIHSKQKGDHGFGYDPIF
IPKKYDVTMAELDPAKKNQISHRKNAIDQLEKWLHTI

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=192, Percent_Identity=43.2291666666667, Blast_Score=154, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17556833, Length=197, Percent_Identity=26.3959390862944, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920712, Length=187, Percent_Identity=31.0160427807487, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_OCEIH (Q8EPJ6)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693026.1
- ProteinModelPortal:   Q8EPJ6
- SMR:   Q8EPJ6
- GeneID:   1017738
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2105
- NMPDR:   fig|221109.1.peg.2103
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- BioCyc:   OIHE221109:OB2105-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 22020; Mature: 22020

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIVATKNKGKAKEFKEFFASFDIEAISLLDLPESIPDIEETGTTFEENAALKAEQIS
CCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCHHCCCHHHHHHH
ERFNTAVIADDSGLLIDALDGRPGLYSARYAGEPTNDQANIEKVLKEMQDVPDNDRSARF
HHHCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEE
ICVLAIAQPGKETNFCTGYCEGHIHSKQKGDHGFGYDPIFIPKKYDVTMAELDPAKKNQI
EEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCCCEEHHHCCCHHHHHH
SHRKNAIDQLEKWLHTI
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIIVATKNKGKAKEFKEFFASFDIEAISLLDLPESIPDIEETGTTFEENAALKAEQIS
CCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCHHCCCHHHHHHH
ERFNTAVIADDSGLLIDALDGRPGLYSARYAGEPTNDQANIEKVLKEMQDVPDNDRSARF
HHHCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEE
ICVLAIAQPGKETNFCTGYCEGHIHSKQKGDHGFGYDPIFIPKKYDVTMAELDPAKKNQI
EEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCCCEEHHHCCCHHHHHH
SHRKNAIDQLEKWLHTI
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376