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The map label for this gene is ktrA [H]

Identifier: 23099117

GI number: 23099117

Start: 1706304

End: 1706981

Strand: Direct

Name: ktrA [H]

Synonym: OB1662

Alternate gene names: 23099117

Gene position: 1706304-1706981 (Clockwise)

Preceding gene: 23099116

Following gene: 23099118

Centisome position: 47.0

GC content: 32.74

Gene sequence:

>678_bases
ATGCCAAGAAGAATTAGTGGGAAGAAGAAACAATTTATTGTCATTGGATTAGGTAGTTTTGGAGGAAGTATTACCAGAGA
GCTTTATTATTTAGGGTGTGATGTTTTAGCTATTGATAAAGACATCGAAAAAGTTAAAAAGTATATGCCGTATACGATCC
ATGCTGTCCAATTAGATAGTACAGACGAAGAAGCGTTAAATAGTCTTGGAGTATCCAATTTTGACCATGTTGTTGTAGCA
ATTGGAGATAATATTCAATCAAGTGTACTAACCACTTTAATCCTTAAAGAATTAGGGACAGATAAAGTATGGGTTAAAGC
TGAGAATAGACATCATCAAAATGTCCTTACTAAAATCGGAGCAGATTTAGTTATACACCCTGAATCAGATATGGGTTTAA
GAGTAGCACATAACATGGCGTCGGAGAAAATTGTTGATTATATAAATTTATCAAATGAATATAGTATTGTAGAATTAGTT
GCTTCTAAAAAAATTCACAATAAAAGTCTATTAGAATTAGATTTAAGAGCAAAATTCGGTGTGACTATCCTAGCAATAAA
AACAAAGGAGGGAATTAATGTCTCTCCGCATCCTGATGAGATTATTCCAGAGGGATCTATTCTAGTAACTATGGGAAGTA
ATCAATCTATACGAAAATTTGAGGAAAAGGGGATATAA

Upstream 100 bases:

>100_bases
CTAATCCGACAGCTAACCTCGTAAGCGTCATAGGGAGAAAAGGTCTTATTTCTAGACCATTTCTTTGTAATGGTTTTTTA
ATGTCAAAGGAGTGGTGAAA

Downstream 100 bases:

>100_bases
ATGATGAGTCGCTTTCCAATATTTTGGAAACTTTCACTAAATCCTCCTCAGATTTTAACATTAGGGTTTATAGCAGTAAT
AATAGTAGGTACATTTTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: K(+)-uptake protein ktrA [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MPRRISGKKKQFIVIGLGSFGGSITRELYYLGCDVLAIDKDIEKVKKYMPYTIHAVQLDSTDEEALNSLGVSNFDHVVVA
IGDNIQSSVLTTLILKELGTDKVWVKAENRHHQNVLTKIGADLVIHPESDMGLRVAHNMASEKIVDYINLSNEYSIVELV
ASKKIHNKSLLELDLRAKFGVTILAIKTKEGINVSPHPDEIIPEGSILVTMGSNQSIRKFEEKGI

Sequences:

>Translated_225_residues
MPRRISGKKKQFIVIGLGSFGGSITRELYYLGCDVLAIDKDIEKVKKYMPYTIHAVQLDSTDEEALNSLGVSNFDHVVVA
IGDNIQSSVLTTLILKELGTDKVWVKAENRHHQNVLTKIGADLVIHPESDMGLRVAHNMASEKIVDYINLSNEYSIVELV
ASKKIHNKSLLELDLRAKFGVTILAIKTKEGINVSPHPDEIIPEGSILVTMGSNQSIRKFEEKGI
>Mature_224_residues
PRRISGKKKQFIVIGLGSFGGSITRELYYLGCDVLAIDKDIEKVKKYMPYTIHAVQLDSTDEEALNSLGVSNFDHVVVAI
GDNIQSSVLTTLILKELGTDKVWVKAENRHHQNVLTKIGADLVIHPESDMGLRVAHNMASEKIVDYINLSNEYSIVELVA
SKKIHNKSLLELDLRAKFGVTILAIKTKEGINVSPHPDEIIPEGSILVTMGSNQSIRKFEEKGI

Specific function: Catalytic subunit of the ktrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and ktrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 24934; Mature: 24803

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRRISGKKKQFIVIGLGSFGGSITRELYYLGCDVLAIDKDIEKVKKYMPYTIHAVQLDS
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHCCEEEEEEEECC
TDEEALNSLGVSNFDHVVVAIGDNIQSSVLTTLILKELGTDKVWVKAENRHHQNVLTKIG
CHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCC
ADLVIHPESDMGLRVAHNMASEKIVDYINLSNEYSIVELVASKKIHNKSLLELDLRAKFG
CCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCC
VTILAIKTKEGINVSPHPDEIIPEGSILVTMGSNQSIRKFEEKGI
EEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCC
>Mature Secondary Structure 
PRRISGKKKQFIVIGLGSFGGSITRELYYLGCDVLAIDKDIEKVKKYMPYTIHAVQLDS
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHCCEEEEEEEECC
TDEEALNSLGVSNFDHVVVAIGDNIQSSVLTTLILKELGTDKVWVKAENRHHQNVLTKIG
CHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCC
ADLVIHPESDMGLRVAHNMASEKIVDYINLSNEYSIVELVASKKIHNKSLLELDLRAKFG
CCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCC
VTILAIKTKEGINVSPHPDEIIPEGSILVTMGSNQSIRKFEEKGI
EEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 12086676 [H]