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The map label for this gene is hfq

Identifier: 23099090

GI number: 23099090

Start: 1676835

End: 1677059

Strand: Direct

Name: hfq

Synonym: OB1635

Alternate gene names: 23099090

Gene position: 1676835-1677059 (Clockwise)

Preceding gene: 23099089

Following gene: 28563929

Centisome position: 46.19

GC content: 31.11

Gene sequence:

>225_bases
ATGGCTCAATCCGTTAATATTCAAGATCAGTACTTAAATCAGCTAAGAAAGAATCATATTTCCGTTACTGTATTTTTAAC
AAATGGATTTCAATTACGAGGCTTAGTAAAAGCATTTGATAATTTTACAGTTTTATTAGAAACGGATGGAAAACAGCAGC
TTATCTTTAAGCATGCTATATCCACGTTCTCACCGGTTAAAAATGTTTCACTCGATAAAGAATAA

Upstream 100 bases:

>100_bases
AATCGATGAAAAAATTGAATTTATTTTGAATGATTTAGCAGGAATTTTAGAAGAAAAATCGAATTAATTATTATAGATAG
AAAAGAGGAGGAACTTTCCC

Downstream 100 bases:

>100_bases
TGAAAAAGCCAGCAGCGATAAAGTGAACTGACCTAGTAATATGAGACAAGAAAAAGCACCTATGCTGCCTTTTCCCTGAA
TTGAACAGGGGAGAGGCAGT

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 74; Mature: 73

Protein sequence:

>74_residues
MAQSVNIQDQYLNQLRKNHISVTVFLTNGFQLRGLVKAFDNFTVLLETDGKQQLIFKHAISTFSPVKNVSLDKE

Sequences:

>Translated_74_residues
MAQSVNIQDQYLNQLRKNHISVTVFLTNGFQLRGLVKAFDNFTVLLETDGKQQLIFKHAISTFSPVKNVSLDKE
>Mature_73_residues
AQSVNIQDQYLNQLRKNHISVTVFLTNGFQLRGLVKAFDNFTVLLETDGKQQLIFKHAISTFSPVKNVSLDKE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=70, Percent_Identity=41.4285714285714, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_OCEIH (Q8EQQ9)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692556.1
- ProteinModelPortal:   Q8EQQ9
- SMR:   Q8EQQ9
- GeneID:   1018130
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1635
- NMPDR:   fig|221109.1.peg.1637
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- ProtClustDB:   PRK00395
- BioCyc:   OIHE221109:OB1635-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 8439; Mature: 8308

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSVNIQDQYLNQLRKNHISVTVFLTNGFQLRGLVKAFDNFTVLLETDGKQQLIFKHAI
CCCCCCCCHHHHHHHHHCCEEEEEEEECCEEEHHHHHHCCCEEEEEECCCCHHHHHHHHH
STFSPVKNVSLDKE
HHCCCCCCCCCCCC
>Mature Secondary Structure 
AQSVNIQDQYLNQLRKNHISVTVFLTNGFQLRGLVKAFDNFTVLLETDGKQQLIFKHAI
CCCCCCCHHHHHHHHHCCEEEEEEEECCEEEHHHHHHCCCEEEEEECCCCHHHHHHHHH
STFSPVKNVSLDKE
HHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376