Click here to switch to the map view.

The map label for this gene is dapG [H]

Identifier: 23099066

GI number: 23099066

Start: 1649100

End: 1650335

Strand: Direct

Name: dapG [H]

Synonym: OB1611

Alternate gene names: 23099066

Gene position: 1649100-1650335 (Clockwise)

Preceding gene: 23099065

Following gene: 23099067

Centisome position: 45.42

GC content: 39.4

Gene sequence:

>1236_bases
GTGCAAGTGATGGTCCAAAAATTTGGAGGAACTTCGGTGCAATCCTCAGAAAATAGAGAGCATGTCATTCGTCATATTCG
TGAGGCATTAGTTCAAGAATATAAACTAGTTGTTGTAGTATCTGCTTTAGGTAGAAAACCAGATCCTTATGCGACGGATA
GCTTACTTGGACTTGTAGACTTCCCAACGAATACGAATTCATCACGTGAACTTGACTTGCTTATGTCTTGTGGAGAGGTG
ATTTCTTCTGTCGTTTTATCGAATGAACTTCAAAAAAATCATATTTCTGCGGTTGCTTTAACTGGAGCACAGGCAGGCTT
TGTTACGAATGAAGATTTCAATCGAGCAAAAATAAAAGAAGTGAATCCTACTAGAATCTTAAAAGAATTGGAAACACATG
ATGTTGTAGTCGTAGCCGGGTTCCAAGGGCAAAGTGAGTCTGGTGAAATAACAACGATAGGACGCGGAGGTAGTGACACA
TCTGCTGCAGCTCTGGGTGTTGCTTTATCTGCAGAAAGAATTGAAATTTTTACAGATGTGGAAGGTATTATGACAGCTGA
TCCGCGTGTTGTAAAAAATGCTAGACCACTCGATGTTGTAACGTATACAGAGATATGTAACTTGGCCTATCAAGGAGCAA
AAGTAATTCATCCACGAGCGGTAGAGATTGCGATGCAAGGTAAAATACCGATGCGTATTCGGTCAACTTATTCCGAACAG
TTAGGTACATTAGTTACTTCATCTCGAGTACATGAACTTGGAATGGATATACCTGATCGAATGATAACTGGTATTGCACA
TATCTCTCCAGTAACGCAAATTAAAGTTCAGACAAAAGAATCAGCTTATCGTGTTCAATCAGAAGTATTTAAAGCGATGG
CTGAAGCAGGTATATCGGTAGATTTTATTAATATATCTCCGACCGGTGTTGTCTATACAGTTCCAGATACTTTAACAACT
AAAGCAATAGAGATATTAGAAATGTTAGGATTTCATCCTGAGGTAACCAAAGGATGTGCCAAAGTATCTGCAGTAGGAGC
TGGAATGAGTGGTGTTCCAGGTGTTGCATCTAAAATCGTGCAGGCATTAACCGATTCTGGTGTGCAAATTCTGCAGTCTG
CAGATAGTCATACCACGATTTGGGTATTAGTGCATAATGATGATTTAATTACTGCAGTGAATGCATTGCATGATGTTTTT
GGACTTAGTATTACCGAGGAACTACTGGAAAGTTAA

Upstream 100 bases:

>100_bases
CACAAACTTTAATTGAGAAAGATTGGTTAAAAAAATAACCCAATACAAAAATACAATCATCCAATAGTCAAACTTGGATA
GCTTATAGAGGTGTTTTAAA

Downstream 100 bases:

>100_bases
GTGAATAAAACGAAGCAAATAACAGCTGGGCGATAGTCAGAAAATATCTGGATCGTTCAGCTGTTTTTAAATATTGACGA
TTTAATACCGTTCGGAATAT

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MQVMVQKFGGTSVQSSENREHVIRHIREALVQEYKLVVVVSALGRKPDPYATDSLLGLVDFPTNTNSSRELDLLMSCGEV
ISSVVLSNELQKNHISAVALTGAQAGFVTNEDFNRAKIKEVNPTRILKELETHDVVVVAGFQGQSESGEITTIGRGGSDT
SAAALGVALSAERIEIFTDVEGIMTADPRVVKNARPLDVVTYTEICNLAYQGAKVIHPRAVEIAMQGKIPMRIRSTYSEQ
LGTLVTSSRVHELGMDIPDRMITGIAHISPVTQIKVQTKESAYRVQSEVFKAMAEAGISVDFINISPTGVVYTVPDTLTT
KAIEILEMLGFHPEVTKGCAKVSAVGAGMSGVPGVASKIVQALTDSGVQILQSADSHTTIWVLVHNDDLITAVNALHDVF
GLSITEELLES

Sequences:

>Translated_411_residues
MQVMVQKFGGTSVQSSENREHVIRHIREALVQEYKLVVVVSALGRKPDPYATDSLLGLVDFPTNTNSSRELDLLMSCGEV
ISSVVLSNELQKNHISAVALTGAQAGFVTNEDFNRAKIKEVNPTRILKELETHDVVVVAGFQGQSESGEITTIGRGGSDT
SAAALGVALSAERIEIFTDVEGIMTADPRVVKNARPLDVVTYTEICNLAYQGAKVIHPRAVEIAMQGKIPMRIRSTYSEQ
LGTLVTSSRVHELGMDIPDRMITGIAHISPVTQIKVQTKESAYRVQSEVFKAMAEAGISVDFINISPTGVVYTVPDTLTT
KAIEILEMLGFHPEVTKGCAKVSAVGAGMSGVPGVASKIVQALTDSGVQILQSADSHTTIWVLVHNDDLITAVNALHDVF
GLSITEELLES
>Mature_411_residues
MQVMVQKFGGTSVQSSENREHVIRHIREALVQEYKLVVVVSALGRKPDPYATDSLLGLVDFPTNTNSSRELDLLMSCGEV
ISSVVLSNELQKNHISAVALTGAQAGFVTNEDFNRAKIKEVNPTRILKELETHDVVVVAGFQGQSESGEITTIGRGGSDT
SAAALGVALSAERIEIFTDVEGIMTADPRVVKNARPLDVVTYTEICNLAYQGAKVIHPRAVEIAMQGKIPMRIRSTYSEQ
LGTLVTSSRVHELGMDIPDRMITGIAHISPVTQIKVQTKESAYRVQSEVFKAMAEAGISVDFINISPTGVVYTVPDTLTT
KAIEILEMLGFHPEVTKGCAKVSAVGAGMSGVPGVASKIVQALTDSGVQILQSADSHTTIWVLVHNDDLITAVNALHDVF
GLSITEELLES

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=292, Percent_Identity=34.5890410958904, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790455, Length=341, Percent_Identity=28.7390029325513, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790376, Length=328, Percent_Identity=23.780487804878, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320893, Length=372, Percent_Identity=29.3010752688172, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44177; Mature: 44177

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVMVQKFGGTSVQSSENREHVIRHIREALVQEYKLVVVVSALGRKPDPYATDSLLGLVD
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCCCCEEEEEE
FPTNTNSSRELDLLMSCGEVISSVVLSNELQKNHISAVALTGAQAGFVTNEDFNRAKIKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCEECC
VNPTRILKELETHDVVVVAGFQGQSESGEITTIGRGGSDTSAAALGVALSAERIEIFTDV
CCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHEECHHHEEEEECC
EGIMTADPRVVKNARPLDVVTYTEICNLAYQGAKVIHPRAVEIAMQGKIPMRIRSTYSEQ
CHHCCCCCHHHCCCCCCEEEHHHHHHHHHHCCCEEECCCEEEEEECCCCCHHHHHHHHHH
LGTLVTSSRVHELGMDIPDRMITGIAHISPVTQIKVQTKESAYRVQSEVFKAMAEAGISV
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCEE
DFINISPTGVVYTVPDTLTTKAIEILEMLGFHPEVTKGCAKVSAVGAGMSGVPGVASKIV
EEEEECCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QALTDSGVQILQSADSHTTIWVLVHNDDLITAVNALHDVFGLSITEELLES
HHHHHCCHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MQVMVQKFGGTSVQSSENREHVIRHIREALVQEYKLVVVVSALGRKPDPYATDSLLGLVD
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCCCCEEEEEE
FPTNTNSSRELDLLMSCGEVISSVVLSNELQKNHISAVALTGAQAGFVTNEDFNRAKIKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCEECC
VNPTRILKELETHDVVVVAGFQGQSESGEITTIGRGGSDTSAAALGVALSAERIEIFTDV
CCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHEECHHHEEEEECC
EGIMTADPRVVKNARPLDVVTYTEICNLAYQGAKVIHPRAVEIAMQGKIPMRIRSTYSEQ
CHHCCCCCHHHCCCCCCEEEHHHHHHHHHHCCCEEECCCEEEEEECCCCCHHHHHHHHHH
LGTLVTSSRVHELGMDIPDRMITGIAHISPVTQIKVQTKESAYRVQSEVFKAMAEAGISV
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCEE
DFINISPTGVVYTVPDTLTTKAIEILEMLGFHPEVTKGCAKVSAVGAGMSGVPGVASKIV
EEEEECCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QALTDSGVQILQSADSHTTIWVLVHNDDLITAVNALHDVFGLSITEELLES
HHHHHCCHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]